Researchers discovered a new gene mutation linked to myopathy, which causes muscle weakness, movement problems, and learning difficulties. The discovery provides better understanding of the genetic causes of the condition and will enable clinicians to give individuals more precise diagnoses.
Researchers found that women with fewer financial resources are more likely to delay seeking medical attention for breast abnormalities, leading to potential delays in diagnosis and treatment. The study suggests that reducing copays and other 'hidden' costs may improve timeliness of diagnosis in this population.
HS-AGING affects older adults, causing cognitive decline and memory impairment. Recent studies reveal around 20% of dementia cases are misdiagnosed as HS-Aging, highlighting the need for accurate diagnosis and exploration of new therapeutic targets to alter disease progression.
Scientists from the University of Sheffield have partnered with an Indian team to develop a new technology that can rapidly diagnose and treat corneal infections, potentially saving thousands of patients' eyesight. The technology uses polymers that trap bacteria or fungi in place, allowing for easy removal.
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A Swedish study found that teenagers and young adults diagnosed with cancer are at a 60% increased risk of suicide or attempted suicide. The risk is highest during the first year after diagnosis, with suicidal behavior being 1.5-fold higher among cancer patients compared to the general population.
A new smartphone-enabled otoscope attachment and app has been shown to accurately diagnose acute otitis media (ear infections) in children. The device provides high-quality video images of the ear drum, allowing for better understanding of the child's diagnosis and treatment.
A new study found that women experiencing breast cancer often experience positive outcomes, including enhanced interpersonal relationships, increased appreciation for life, and greater spirituality. Increased social support was also linked to more post-traumatic growth in these women.
Researchers found that trauma-related psychophysiologic reactivity is a strong predictor of PTSD diagnosis in the general adult population. This biological marker shows promise for diagnosing PTSD, which affects approximately seven to 12 percent of US adults who have experienced trauma.
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Scientists have developed a new method to visualize gene activity in single cells, revealing strong variability in gene expression and spatial organization between cells. The method allows for the parallel measurement of gene activity and transcript molecules in thousands of single cells, providing novel insights into cell behavior.
A study by Harvard Medical School researchers found that most Massachusetts primary care malpractice claims (72.1%) are related to diagnosis errors, primarily failures to diagnose or delays in cancer diagnosis. Primary care malpractice cases tend to be more difficult to defend and result in more settlements.
Treating strep throat with penicillin can reduce ARF/RHD risk by 70-80%, and including primary prevention in overall strategy is crucial. Global efforts to combat RHD control have shown success through comprehensive strategies involving syndromic treatment, education, and awareness campaigns.
Researchers found that early diagnosis of HIV increases lifetime costs but improves length and quality of life. Activated B cells are identified as an early sign of AIDS-related lymphoma, while new circumcision devices need further development to increase circumcision rates in Africa.
A study found that using electronic health records (EHRs) with computerized and automated growth monitoring led to a higher detection rate of growth disorders in children. The system referred abnormal data for review, resulting in 28 new diagnoses compared to 4 in the control period.
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A multinational study of over 140,000 participants from 17 countries found a significant gap in hypertension detection and control, with only half aware of their diagnosis and one-third being treated effectively. The study highlights the need for substantial improvement in hypertension diagnosis and treatment.
A long-term study found that infants and children with congestive heart failure and genetic disorders have the lowest transplant-free survival rates. Children diagnosed after one year old with unknown cause have the best outcome, a 97% rate of transplant-free survival.
Patients with dementia have a higher rate of urinary and fecal incontinence diagnoses, which can affect treatment decisions. The study analyzed data from 54,816 people with dementia and found that those with both dementia and incontinence were more likely to receive medications and indwelling catheters.
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A review of three recent concussion guidelines highlights areas of consensus, including a definition of concussion, diagnosis, and acute care recommendations. The guidelines emphasize the importance of proper diagnosis and treatment to prevent long-term neurological consequences.
Patients with severe mitral valve regurgitation who undergo surgery early after diagnosis have improved long-term survival and lower risk of heart failure. Long-term survival rates were significantly higher for those who had surgery within three months of diagnosis compared to those who avoided surgery.
UPV/EHU researchers have developed an algorithm capable of diagnosing heart rhythm with just 3 seconds' worth of signal and a methodology to quantify how often massage is interrupted when applying interference-cutting systems. This allows for reliable diagnosis without stopping compressions, improving cardiac resuscitation procedures.
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New study reveals stable survival rates for HIV-associated lymphoma patients during the antiretroviral therapy era. Despite increased incidence and changing demographics, recent diagnosis years are not associated with decreased mortality. The study highlights an ongoing need to improve treatments for this challenging population.
A study of 5-year survival rates among black and white women with breast cancer found that black women continued to have a lower rate of survival. The difference was largely attributed to factors such as poorer health at diagnosis and more advanced disease, rather than treatment differences.
Researchers identified fungal meningitis cases with ischemic stroke after contaminated methylprednisolone injections. The condition presents with varying incubation periods, requiring better recognition of clinical characteristics for efficient care.
Prehabilitation interventions, including physical and psychological support, can reduce treatment-related complications, improve physical and mental health outcomes, and increase treatment options. Benefits include lower complication rates, reduced hospital readmissions, and improved healthcare costs.
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Researchers found that adding foods rich in amino and fatty acids, such as leucine and omega-3 fatty acids, may help youth with Type 1 diabetes produce some of their own insulin for up to two years after diagnosis. This approach could benefit the lives of these children by reducing the risk of diabetes complications.
A Vanderbilt research program trains community pediatricians to diagnose autism, leading to a significant increase in diagnoses within their practices. The training improved diagnostic accuracy and shifted the comfort level of discussing ASD diagnoses with caregivers.
A study published in CMAJ found that 13.5% of Canadian Forces personnel who served in support of the Afghanistan mission between 2001-08 had a mental health disorder related to their deployment. The most common disorders were posttraumatic stress disorder (PTSD) and depression, with PTSD being found in 8% of personnel.
The study found that it took a mean of 5.2 physician visits to obtain the correct diagnosis of cervical spondylotic myelopathy (CSM), highlighting delays in diagnosis due to lack of awareness among primary care physicians and community-based orthopedic surgeons.
Every year, around 700 women with urinary cancers are missing out on prompt diagnosis due to initial misattribution by family doctors. Women were twice as likely to have visited their GP multiple times before being referred to a specialist, leading to delayed diagnoses and poorer survival rates.
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The collaboration aims to lower the average age of diagnosis from four to five years to six to 12 months in the African American community. Autism Speaks will provide materials and guidance to churches and parents on recognizing signs of autism and accessing services.
The National Osteoporosis Guideline Group (NOGG) Update 2013 provides updated guidance on the diagnosis and management of osteoporosis. The new recommendations cover glucocorticoid-induced osteoporosis, calcium and vitamin D therapy, and long-term bisphosphonate therapy.
Replacing carbohydrates with vegetable fat may be associated with a lower risk of death in men with nonmetastatic prostate cancer, according to a study published in JAMA Internal Medicine. The study found that men who consumed more vegetable fat had a lower risk of lethal prostate cancer and all-cause mortality.
A recent study reveals that rare mitochondrial mutations are more prevalent than previously thought, affecting 7.1% of patients with a respiratory chain disorder. Comprehensive analysis of all mitochondrial DNA is crucial for early diagnosis and treatment.
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A recent study reveals that cancer survivors are significantly more likely to experience anxiety, with partners experiencing even more anxiety than survivors. The findings highlight the need for improved screening and follow-up support for both survivors and their families.
A study found statin use may be associated with an increased likelihood of diagnoses of musculoskeletal conditions, arthropathies, and injuries. Statin users had a higher odds ratio for these conditions compared to non-users, but the association was not significant for osteoarthritis/arthropathy.
A clinical study demonstrates the durability of NeuroStar TMS Therapy in patients with Major Depressive Disorder (MDD) who have failed to respond to prior antidepressant medication. After acute treatment, patients maintained significant improvement and remission through 12 months, suggesting a long-term benefit of the therapy.
The Intelligent Clinician's Guide to the DSM-5 explores revisions to the Diagnostic and Statistics Manual, highlighting both strengths and weaknesses. The book provides a balanced assessment of psychiatric diagnosis and treatment, essential reading for mental health professionals navigating the post-DSM-5 era.
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A new study from Fred Hutchinson Cancer Research Center found that cancer patients are more than two-and-a-half times more likely to declare bankruptcy than those without cancer. Younger cancer patients faced the highest bankruptcy rates, particularly in their early 20s and 30s.
A new study published in Journal of Psychiatric Practice reports a hybrid categorical-dimensional diagnostic model proposed for DSM-5 aligns well with the current approach to personality disorder diagnoses. The findings support the adoption of this alternative model, which combines core dimensions of personality disorder with various m...
The guidelines provide evidence-based tools for primary care physicians to diagnose and manage fibromyalgia, recommending exercise, relaxation techniques, and cognitive behavioral therapy. The main goal is to alleviate pain and improve quality of life, with medications tailored to individual patients.
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The American Thoracic Society has released new official guidelines for the diagnosis and management of exercise-induced bronchoconstriction (EIB), a common condition affecting subjects with and without asthma. The guidelines provide practical guidance for clinicians, including treatment recommendations and preventive measures.
A new study found that only 38.4% of adults with clinician-identified depression met the 12-month criteria for depression. Many participants used prescription psychiatric medication despite not meeting the criteria, highlighting the need for improved diagnosis and treatment targeting in community settings.
A new study by the University of Leicester found that women from deprived areas have poorer breast cancer survival rates due to late-stage diagnoses. The research suggests that prioritizing early detection in these areas can significantly improve survival chances and reduce deaths.
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Researchers at Yale University have discovered a key marker to identify newborns at risk for autism: abnormal placental folds and cell growths called trophoblast inclusions. This breakthrough allows for earlier diagnosis and treatment, potentially improving outcomes.
A new study at Rhode Island Hospital found that many older women are overdiagnosed and overtreated for urinary tract infections (UTIs), highlighting the importance of accurate diagnosis. The study suggests that collecting urine by inserting a temporary catheter may reduce false-positive results and unnecessary antibiotic exposure.
A new algorithm optimizes tube potential for patients undergoing lumbar spine CT exams, resulting in a 41% reduction in radiation dose. The study found that lower kilovoltage images maintained diagnostic quality despite increased image noise.
A new study from the University of Wisconsin-Madison found that age at diagnosis for children with autism depends on specific behavioral symptoms. Children exhibiting impairments in nonverbal communication and repetitive behaviors were more likely to be diagnosed earlier.
Despite a decline in spontaneous stillbirths, stillbirth rates in British Columbia, Canada, have increased by 31% over the past decade, according to a study published in CMAJ. The increase was mainly due to prenatal diagnosis and pregnancy terminations of fetuses with congenital anomalies.
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A new study published in the Journal of Clinical Oncology found that alcohol consumption before and after diagnosis has no impact on breast cancer survival. However, moderate drinkers may have a reduced risk of dying from cardiovascular disease, with moderate wine consumption associated with a lower risk.
A large observational follow-up study found that women with lung cancer who consumed more soy food prior to diagnosis lived longer. Soy contains isoflavones that may affect molecular pathways involved in tumor development and growth.
The new Guidance emphasizes the importance of early diagnosis and treatment for postmenopausal osteoporosis, citing high fracture rates and low treatment adherence. The report provides updated guidelines for assessing fracture risk, management algorithms, and nutritional recommendations to prevent fractures.
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Researchers at Thomas Jefferson University have created a new anatomically-based classification for diagnosing cervical spinal stenosis, which helps identify patients requiring urgent surgical intervention. The study found that patients with higher grades of stenosis were more likely to receive spinal decompression recommendations.
A new UCSF study shows that using discharge diagnoses to determine ER visit validity could dissuade patients from seeking emergency care for serious conditions. The research highlights the complexity of the issue, suggesting strategies to narrow ER use may not improve health or lower costs.
A study found that only 6.3% of emergency department visits with primary care-treatable diagnoses also had nonemergency complaints, highlighting the flaws in using discharge diagnosis to predict ED use. Patients with nonemergency-complaint ED visits often required immediate emergency care or hospital admission.
A new study analyzed 6.2 million patients and found that 74.6% of men with erectile dysfunction remained untreated, highlighting the need for improved treatment access and awareness. The study also showed that treatment frequency varied by co-morbidities, with hypogonadism being a key factor in treatment usage.
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A recent study published in the Journal of the National Cancer Institute found that consuming high-fat dairy products following breast cancer diagnosis increases the risk of dying from the disease. The study tracked over 1,800 women and found an association between high-fat dairy intake and poorer breast cancer survival.
A study of over 1,100 women found that nearly a quarter developed post-traumatic stress disorder (PTSD) symptoms within two to three months after breast cancer diagnosis. Younger women and those from Asian and black backgrounds were at higher risk.
A recent review of 400 patients with Wolfram syndrome reveals that 15% do not meet current diagnostic criteria, highlighting the need for revision. The study proposes expanding the diagnostic criteria to identify two of four clinical features, which would diagnose up to 98% of patients.
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A large study of nearly 60,000 patients found that stage at diagnosis only partly explains the wide variation in lung cancer survival rates among different developed countries. Treatment differences also played a key role, with some countries experiencing lower survival rates due to delays in diagnosis or suboptimal staging.
Research suggests that sedentary behavior is not an independent risk factor for death among breast cancer survivors, contrary to previous suggestions. Regular moderate-to-vigorous intensity physical activity may reduce the risk of death in this population.
A study published in JNCI Journal of the National Cancer Institute found that median out-of-pocket costs for Canadian breast cancer patients were $1,002, with higher costs among more educated women and those living far from hospitals. Wage losses had a greater impact on family finances than out-of-pocket costs.