A new study sheds light on fatty liver disease MASH's pathology, revealing T cell activation and growth in response to poor diet. The research holds promise for developing a biomarker test to track disease progression before it's at a late stage.
A recent study published in JAMA Pediatrics found that meal-replacement therapy paired with financial incentives resulted in a greater reduction in body mass index compared to MRT alone. The study enrolled 126 adolescents and found that the combination treatment led to a significant decrease in BMI and total body fat mass.
A new study found that prenatal ozone exposure significantly raises BMI and weight-for-age Z scores in children, increasing the risk of obesity. The research suggests that stringent air quality regulations are needed to protect children's health and development.
A recent study found that for every same increase of BMI, fat mass and type 2 diabetes risk are increased in taller people. The authors hypothesize that the cardiometabolic risk of a higher BMI may be underestimated in taller grown populations worldwide.
Researchers discovered that young adults with higher levels of inflammation were more likely to experience reduced cognitive function in midlife. Higher inflammation was associated with lower performance on skills testing and differences in executive functioning.
Researchers have discovered that alterations in the human gene TRPC5 cause obesity and postpartum depression. Studies using cells, animal models, and humans showed TRPC5 acts on distinct neuronal populations in the hypothalamus, a brain region regulating feeding, anxiety, socialization, and maternal care.
A genetic study discovered a gene, TRPC5, associated with obesity, behavioral problems, and postnatal depression in mothers. Oxytocin may alleviate symptoms, suggesting it as a potential treatment for postnatal depression.
A recent study published by American Society for Nutrition found that paternal fish oil supplementation can lead to lower body weight and improved metabolic health in offspring. Researchers gave male mice a high-fat diet with or without added fish oil, then mated them with female mice on a healthy low-fat diet.
A survey of pediatric bariatric surgeons found significant variation in the use of weight loss medications, particularly GLP-1As, in young patients. Most respondents prescribe GLP-1As for patients considering MBS, but preoperative and postoperative practices vary widely.
A study of 4,782 Sri Lankan children aged 10-18 with dengue found that obese individuals were more than twice as likely to be hospitalized due to the disease. The research highlights the potential consequences of rising childhood obesity rates on public health.
Research highlights need for prevention and treatment approaches for children with obesity born underweight, finding links between low birth weight and cardiometabolic disease risks. Visceral fat storage issues contribute to type 2 diabetes risk.
The USPSTF recommends providing or referring children and adolescents with a high body mass index (BMI) to comprehensive behavioral interventions. Approximately 19.7% of US children aged 2-19 have a BMI at or above the 95th percentile, with higher prevalence among Hispanic/Latino, Native American/Alaska Native, and lower-income families.
The study found that 1 in 5 children and adolescents experience excess weight, with rates varying by region. Excess weight is linked to multiple factors, including inherent, behavioral, environmental, and sociocultural influences.
Research published in the Stroke journal found that teenage women who were overweight or obese had a higher risk of ischemic stroke before age 55. The study analyzed data from over 50 years and suggested that even temporary excess weight may have long-term health effects.
By 2050, at least 61% of US adults (184 million people) are projected to have some type of cardiovascular disease, with total costs tripling to $1.8 trillion. Population shifts, high blood pressure, and obesity will drive this increase.
Longitudinal study finds that higher baseline body mass index is associated with more depressive symptoms over time. Children's cognitive performance also declines as they enter adolescence, highlighting the importance of monitoring children with overweight or obesity for depression problems.
A study suggests that women who underwent sleeve gastrectomy before pregnancy had children who gained more weight per month in the first three years of life. In contrast, those born to mothers who had Roux-en-Y gastric bypass surgery experienced slower weight gain. Researchers found this difference after adjusting for various factors, ...
A new study found that children who are sedentary for more than six hours a day have a significantly increased risk of severe fatty liver disease and liver cirrhosis by young adulthood. Engaging in light-intensity physical activity for at least 3 hours a day can reverse premature liver damage.
The SELECT Trial found semaglutide to significantly reduce the risk of kidney-related complications and improve kidney function in individuals with overweight or obesity and cardiovascular disease. The study revealed that semaglutide's ability to prevent macroalbuminuria was a key factor in reducing kidney-related events.
The Endocrine Society will unveil new research on male birth control and anti-obesity medications during ENDO 2024 news conferences. The society's Vitamin D Clinical Practice Guideline is also being shared publicly for the first time, featuring discussions on its recommendations.
Researchers are studying the early brain development of babies born to mothers with diabetes to understand the link between prenatal exposure and later childhood obesity. They aim to identify key differences in brain structure and function that may contribute to the increased risk of obesity.
A new study found that rates of obesity and severe obesity increased among Black, Hispanic, and foreign-born students in NYC public schools. Despite overall decline in obesity prevalence, these groups saw significant increases, with Black students experiencing a larger relative increase.
A new study quantifies the impact of childhood obesity on long-term health and life expectancy. Childhood obesity was found to have a profound effect, with a child living with severe obesity at age 4 having a life expectancy of just 39 years. Weight loss can give back decades of life.
Research suggests that the source of sugar, rather than the amount consumed, is crucial in developing obesity in children. A study found that children who got their sugar from unsweetened dairy products and fruit had a lower risk of becoming overweight or obese.
A UK Biobank study suggests that adults living with obesity who were underweight or average weight in childhood may be at increased risk of all-cause mortality. The study found that adult men and women who reported being thinner as children had higher mortality risks, with a 63% and 60% increase respectively.
Researchers from Children's Hospital of Philadelphia have identified a causal genetic variant strongly associated with childhood obesity. The study highlights the importance of the hypothalamus in regulating food intake and provides new insights into potential therapeutic targets.
Scientists at St. Jude Children's Research Hospital found that improving metabolic health in obese mice before flu vaccination but not after, protects against influenza virus. A healthy diet improved T-cell function and a robust anti-flu response during later exposure.
A new series of studies will test the effectiveness of PATCH, a USC-designed wearable device that accurately captures everyday activities. The device integrates multiple sensors to measure physical activity, sedentary time, and sleep in children.
A new study found that increased childhood sedentary time is associated with higher blood insulin concentration and a greater risk of excess insulin and insulin resistance. Light physical activity was shown to reduce the risk of excess insulin by 20%, while moderate-to-vigorous physical activity had a smaller effect.
Healthcare professionals express frustration with limited time and training to support families in addressing childhood obesity. They highlight the need for dedicated services and practical advice to help parents make healthy lifestyle changes.
Research finds children's weight at age 8 and pubertal BMI changes independently predict high blood pressure in mid-life. Targeted initiatives for preventing childhood obesity may reduce disease burden.
A study found that children and adolescents with obesity are at a significantly higher risk of developing multiple sclerosis, with the risk being more than two-fold. The study also suggests that the persistent low-grade inflammatory state associated with obesity may be mediating this association.
The study found that obesity rates have nearly tripled in adult men and doubled in women since 1990. The prevalence of malnutrition is now the most common form of malnutrition globally, affecting nearly 880 million adults and 160 million children. Obesity can lead to comorbidities like high blood pressure, heart disease, and diabetes.
A study published in JAMA Pediatrics found that the prevalence of overweight and obesity among 3- and 4-year-olds in Sweden has decreased after the pandemic. The researchers observed a reversal of unhealthy weight trends, indicating that an unhealthy weight status can be reversed.
A researcher is studying patterns of weight gain and BMI increases in children based on behavioral, social, environmental, and biological factors. The study aims to identify monthly patterns in BMI change and associated behaviors.
Research in Canada found that kids perceive sponsored sports as 'generous' and 'cool', increasing their desire to purchase unhealthy products. The study suggests regulatory actions are necessary to protect children from unhealthy food marketing.
A new study found that short-term very low calorie diets are safe and acceptable for teenagers with moderate to severe obesity, with most experiencing rapid weight loss and some reporting side effects. The diets were closely monitored by an experienced dietitian and included meal replacements to ensure essential nutrient requirements.
A new study from the University of Illinois found that changes in home food availability between 2 to 4 years old are associated with changes in nutrient intake. The researchers used the Home Food Inventory (HFI) to measure food availability and found significant changes in several food categories over time.
Research by Norwegian University of Science and Technology finds that high-intensity interval training increases breast milk's adiponectin levels, a hormone linked to insulin resistance and type 2 diabetes. This could help prevent childhood obesity.
Research by Queen Mary University of London found that girls with obesity are 1.7 times more likely than those with a healthy weight to have at least one GP consultation for musculoskeletal symptoms or diagnosis in childhood. Knee pain was the most common symptom reported, and researchers hope their findings will raise awareness about ...
A study found that maternal obesity increases the risk of developing liver disease and liver cancer in offspring, due to the transmission of an altered gut microbiota. The risk is significantly higher in mice fed a junk food diet, highlighting the importance of microbiome health.
A new study finds that Latinx children with unreliable access to food at age 4 are nearly four times more likely to develop fatty liver disease later. The researchers recommend earlier screening for metabolic dysfunction-associated steatotic liver disease (MASLD) and ensuring public meal programs offer nutritious meals.
A study published in Public Health Nutrition found that unhealthy food retailers and advertisements dominate urban school neighborhoods in Greater Tunis, contributing to high rates of childhood obesity. The researchers analyzed over 3600 retailers and nearly 2100 advertisements, revealing that two-thirds were classified as unhealthy, w...
A new study found that waist circumference-to-height ratio detects excess fat mass and distinguishes it from muscle mass in children and adolescents significantly better than body mass index (BMI). The measure is inexpensive and accurate, making it a promising alternative to BMI for diagnosing childhood obesity.
A study published in Pediatric Research found that waist circumference-to-height ratio accurately detects fat obesity in children and adolescents, distinguishing it from muscle mass. This method is more effective than BMI in predicting premature death and could replace BMI as an assessment tool for childhood obesity.
Researchers found unique bacteria taxa in normal-weight children vs overweight/obese children, suggesting BPA promotes different microbial communities. Gut microbiota responds differently to BPA exposure depending on BMI.
Researchers at Pennington Biomedical confirmed the accuracy of remotely gathered physical measurements for children in a weight management study. The findings support the value of remote height and weight measurements for both research and clinical purposes.
The study highlights the urgent need to tackle obesity and underweight globally, particularly in poor countries. Obesity rates have surpassed one billion, with combined rates of underweight and obesity being more common than malnutrition in many countries.
A new study published in the American Journal of Respiratory and Critical Care Medicine found that childhood tonsillectomy is not associated with an increased risk of obesity in adulthood. The research followed 132 children who underwent tonsillectomy for obstructive sleep apnea and found no link to weight gain in adulthood.
A longitudinal study of 5,000 Australian children found a strong correlation between parents who smoke and their children's consumption of high-calorie, unhealthy foods. The link between parental smoking and childhood obesity transcends socio-economic classes.
A study published in Obesity Facts found that reducing sedentary time in the classroom led to a significant reduction in waist-to-height ratio and an increase in sport participation among primary school children. The approach, called Active Movement, integrates non-sedentary behavior and low-level physical activity into daily routine.
Rats fed high-fructose diets exhibit disturbances in autonomic nervous and cardiovascular systems, increasing risk of chronic diseases like diabetes and obesity. Fructose consumption by parents is also associated with impaired physiological regulation of their offspring's cardiovascular system.
Research suggests that high aerobic fitness in children with overweight or obesity is linked to improved executive functions, academic performance, and larger brain volume. The 20-meter shuttle run test is a reliable predictor of brain health outcomes in this population.
The COVID-19 pandemic caused a 45% increase in childhood obesity among 4-5-year-olds in England, persisting into 2022. The study found that this group will incur an additional £800 million in healthcare costs over their lifetimes.
A new analysis of health data found that prenatal and infant nurse home visits significantly reduced the likelihood of daughters being obese by 55% and mothers experiencing hypertension by 39%. The study also showed a decrease in severe obesity and Stage 1-2 hypertension in adolescence. Early intervention through public programs like n...
A new NIH study finds that consistently breastfeeding infants in their first three months is associated with a lower risk of childhood obesity, regardless of the mother's pre-pregnancy BMI. The study suggests that health professionals can encourage and promote breastfeeding among all women, especially those who have obesity.
A study of 620,000 children found that maternal type 1 diabetes was associated with increased risk for most types of congenital heart defects in offspring. Obesity and overweight were linked to increased risk for complex defects, such as outflow tract obstruction, while decreasing the risk for ventricular septal defects.
A new study found that light physical activity can completely reverse the adverse process of childhood obesity linked to sedentary time. Children who engaged in at least 3 hours a day of light physical activity had a 9.5-15% decrease in overall fat mass gain during adolescence.
A new study published in PLOS Medicine found no association between assisted reproductive technologies and body mass index in children, except when using frozen embryos. The study analyzed data from Denmark and other countries, providing insights into the health outcomes of children born through assisted reproductive technologies.
Research suggests that childhood sedentariness contributes to elevated cholesterol levels and premature heart attack or stroke in mid-life. Engaging in light physical activity for 3-4 hours/day may be effective in reducing high cholesterol.