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American College of Cardiology issues scientific statement on inflammation and cardiovascular disease

The American College of Cardiology has released a scientific statement on inflammation and its connection to various cardiovascular diseases, including coronary artery disease and heart failure. The statement confirms years of research confirming the importance of inflammation as an underlying contributor to CVDs.

SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateSep 29, 2025

Family Heart Foundation announces recommendations to improve universal screening for underdiagnosed genetic condition in children, which causes early onset cardiovascular disease

A multidisciplinary panel published in the Journal of Pediatrics advocates for accelerated diagnosis of familial hypercholesterolemia, a life-threatening genetic condition. Universal lipid screening is recommended to identify affected children at high risk of heart disease decades earlier than those without the condition.

SourceFamily Heart Foundation·JournalThe Journal of Pediatrics·TypeSystematic review·DateSep 23, 2025

Valentin Fuster, MD, Ph.D., given prestigious honor of presenting the inaugural World Heart Federation oration lecture

Dr. Valentin Fuster, a renowned cardiovascular expert, has been awarded the inaugural World Heart Federation oration lecture for his groundbreaking work in promoting global cardiovascular health. He will discuss early detection and education as key strategies for preventing heart disease, focusing on low- and middle-income countries.

New Study identifies early signs of valve failure one year after TAVI, raising durability concerns in younger patients

A new study published in The Annals of Thoracic Surgery found that over 6% of patients experienced early hemodynamic valve deterioration just one year after undergoing TAVI. Smaller implanted valve sizes were significantly associated with the development of HVD, while larger valves appeared to be protective.

SourceThe Society of Thoracic Surgeons·JournalThe Annals of Thoracic Surgery·DateAug 18, 2025

Safflower yellow pigments in coronary heart disease: Mechanisms, applications, and future perspectives

Safflower yellow pigments have demonstrated clear clinical efficacy in the treatment of coronary heart disease, with anti-myocardial ischemia, mitigation of ischemia-reperfusion injury, and reduction of atherosclerotic damage. Their mechanisms involve inhibition of inflammatory responses, oxidative stress, and platelet aggregation.

SourceXia & He Publishing Inc.·JournalFuture Integrative Medicine·DateJul 28, 2025

Still top cause of death, the types of heart disease people are dying from is changing

Research reveals significant drop in heart attack deaths, while increases observed in deaths from heart failure, arrhythmias, and hypertensive heart disease over the past 50 years. Studies suggest advancements in medical treatment, bystander CPR, and public health initiatives have contributed to these findings.

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateJun 25, 2025

Living near an ocean polluted by microplastics may increase cardiometabolic disease risk

A new study published in the Journal of the American Heart Association found that residents in U.S. coastal counties near ocean waters with high concentrations of microplastics are at higher risk for Type 2 diabetes, coronary artery disease, and stroke. The study analyzed data from 152 counties and found a significant association betwe...

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateJun 18, 2025

Family Heart Foundation announces results of real-world study in 273,770 individuals with cardiovascular disease demonstrating that risk of subsequent cardiovascular event increases with rising lipoprotein(a) levels

A study of 273,770 individuals with cardiovascular disease found that increasing lipoprotein(a) levels significantly increases the risk of subsequent cardiovascular events. Treatment with high-impact LDL-C lowering therapies may help reduce this risk.

SourceFamily Heart Foundation·JournalEuropean Heart Journal·TypeData/statistical analysis·DateMay 7, 2025

Simple test could better predict your risk of heart disease

Researchers found that measuring lipoprotein markers in a simple blood test can identify individuals at high risk of cardiovascular disease more effectively. The study analyzed data from over 200,000 people and showed that the total number of 'bad cholesterol' particles is the most important factor to consider when testing for future h...

SourceChalmers University of Technology·JournalEuropean Heart Journal·TypeObservational study·DateApr 28, 2025

Drug candidate successfully treats atherosclerosis, fatty liver disease in large mammals

Researchers successfully treated atherosclerosis and fatty liver disease using DT-109 in nonhuman primates, which has potential as a dual therapy for two common conditions. The compound reduced the formation of atherosclerotic plaques and stopped critical processes that lead to vascular calcification.

SourceMichigan Medicine - University of Michigan·JournalSignal Transduction and Targeted Therapy·TypeExperimental study·DateApr 23, 2025

Extensive mapping of genes behind cardiovascular disease

Swedish researchers have identified 20 genetic variants associated with an increased risk of atherosclerosis, a leading cause of cardiovascular disease. The study used advanced imaging techniques to examine millions of genetic variants, providing new insights into the disease process and potential ways to prevent it.

SourceUniversity of Gothenburg·JournalNature Communications·TypeObservational study·DateMar 31, 2025

Oral semaglutide vastly reduces heart attacks, strokes in people with type 2 diabetes

A new clinical trial found that oral semaglutide can significantly reduce cardiovascular events in people with type 2 diabetes and pre-existing cardiovascular disease. The medication decreased the risk of major cardiac events by 14% compared to placebo, with nonfatal myocardial infarction seeing the greatest reductions in risk.

SourceUniversity of North Carolina Health Care·JournalNew England Journal of Medicine·DateMar 29, 2025

Remote booster program after cardiac rehabilitation reduces daily sitting time

A remote booster program after cardiac rehabilitation significantly reduces daily sitting time and increases light physical activity, lowering the risk of cardiovascular diseases. Participants who received coaching via phone and digital communication showed a clear improvement in sedentary behavior and increased physical activity.

SourceRadboud University Medical Center·JournalEuropean Journal of Preventive Cardiology·TypeRandomized controlled/clinical trial·DateMar 25, 2025

HIV not associated with higher risk for coronary artery disease in Uganda, challenging prior notions of health risks among regional populations with HIV

A cross-sectional study of Ugandan adults with and without HIV found the prevalence of coronary atherosclerosis disease to be much lower than expected in similar populations in the Global North. The study's results refute prior notions that well-controlled HIV infection is associated with increased CAD risk.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeNews article·DateMar 12, 2025

Attitude towards a moderate aortic valve dysfunction during rheumatic mitral valve surgery: a retrospective cohort study

Research on treating moderate aortic valve dysfunction during rheumatic mitral valve surgery shows concomitant aortic valve surgery may improve echocardiographic outcomes. The study suggests delaying aortic valve surgery may be a viable option for patients with moderate predominant aortic regurgitation.

SourceNational Center for Respiratory Medicine·JournalJournal of Thoracic Disease·TypeObservational study·DateFeb 25, 2025

Kennesaw State researcher earns American Heart Association award for innovative study on heart disease diagnostics

Kennesaw State researcher Chen Zhao has earned the 2025 American Heart Association Institutional Research Enhancement Award for his innovative study on non-invasive blood flow prediction in cardiovascular disease diagnosis. His technology uses coronary computed tomography angiography (CCTA) scans to measure Fractional Flow Reserve (FFR...

A patient’s ability to perform a cardiac stress test offers a critical window on their mortality risk

A study published in Mayo Clinic Proceedings found that patients who can exercise during cardiac stress testing have a lower mortality rate than those who cannot. The researchers discovered that assessing a patient's ability to exercise during testing provides a stronger distinction between high- and low-risk patients.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalMayo Clinic Proceedings·TypeObservational study·DateFeb 19, 2025