Articles tagged with Coronary Artery Disease
Researchers successfully treated atherosclerosis and fatty liver disease using DT-109 in nonhuman primates, which has potential as a dual therapy for two common conditions. The compound reduced the formation of atherosclerotic plaques and stopped critical processes that lead to vascular calcification.
Scientists developed a machine learning model that incorporates factors such as genetics, lifestyle, and medical history to predict CAD risk. The new model outperformed the standard clinical model, identifying individuals at highest risk of developing CAD more accurately.
Using intravascular imaging (IVI) to guide stent implantation reduces death, stent thrombosis, and repeat procedures in severely calcified lesions. IVI outperforms conventional angiography in improving patient outcomes.
A new study from Intermountain Health shows the gap in heart disease outcomes between men and women is narrowing, with no significant differences by sex from 2015-2019. Women tend to have more comorbidities and stable chest pain, but less severe blockage and revascularization compared to men.
Swedish researchers have identified 20 genetic variants associated with an increased risk of atherosclerosis, a leading cause of cardiovascular disease. The study used advanced imaging techniques to examine millions of genetic variants, providing new insights into the disease process and potential ways to prevent it.
Despite a rise in long distance running participation, cardiac arrests during US marathons and half-marathons have shown no significant increase, indicating improved emergency response measures are at play.
Researchers studied women with ischemia symptoms without blockages in their heart arteries. The five-year trial found no significant difference between intensive medical therapy and usual care for serious cardiovascular events.
A new clinical trial found that oral semaglutide can significantly reduce cardiovascular events in people with type 2 diabetes and pre-existing cardiovascular disease. The medication decreased the risk of major cardiac events by 14% compared to placebo, with nonfatal myocardial infarction seeing the greatest reductions in risk.
A growing body of evidence suggests a significant link between human papillomavirus (HPV) and heart disease. Researchers pooled data from nearly 250,000 patients in seven studies, finding HPV-positive individuals had a 40% higher likelihood of developing cardiovascular disease.
A remote booster program after cardiac rehabilitation significantly reduces daily sitting time and increases light physical activity, lowering the risk of cardiovascular diseases. Participants who received coaching via phone and digital communication showed a clear improvement in sedentary behavior and increased physical activity.
A cross-sectional study of Ugandan adults with and without HIV found the prevalence of coronary atherosclerosis disease to be much lower than expected in similar populations in the Global North. The study's results refute prior notions that well-controlled HIV infection is associated with increased CAD risk.
The study found that combining coronary calcium score with a primary prevention strategy in intermediate-risk patients with a family history of coronary artery disease reduces atherogenic lipids and slows plaque progression compared to usual care. This data supports the use of CAC scores to assist intensive preventive strategies.
Preoperative anemia is a recognized risk factor for adverse outcomes in CABG, but it does not affect the long-term survival advantage associated with CABG. This study provides evidence that surgical intervention can still be beneficial for ICM patients despite preoperative anemia.
A novel LASSO-derived model was developed to predict coagulation disorders after coronary artery bypass grafting (CABG) in elderly individuals. The model demonstrated good prediction performance, identifying preoperative and intraoperative variables associated with coagulation disorders.
Research on treating moderate aortic valve dysfunction during rheumatic mitral valve surgery shows concomitant aortic valve surgery may improve echocardiographic outcomes. The study suggests delaying aortic valve surgery may be a viable option for patients with moderate predominant aortic regurgitation.
Kennesaw State researcher Chen Zhao has earned the 2025 American Heart Association Institutional Research Enhancement Award for his innovative study on non-invasive blood flow prediction in cardiovascular disease diagnosis. His technology uses coronary computed tomography angiography (CCTA) scans to measure Fractional Flow Reserve (FFR...
A study published in Mayo Clinic Proceedings found that patients who can exercise during cardiac stress testing have a lower mortality rate than those who cannot. The researchers discovered that assessing a patient's ability to exercise during testing provides a stronger distinction between high- and low-risk patients.
A new deep learning technique called CTLESS enhances myocardial perfusion imaging accuracy without requiring additional radiation scans. This method leverages deep learning to estimate attenuation maps, improving diagnostic interpretation and potentially boosting technological health equality across the U.S. and worldwide.
A cross-sectional study found that TV football game food ads are often high in sodium, calories, and fat content. This can pose a risk to adults with pre-existing heart conditions, who may be vulnerable to dietary deviations due to frequent exposure to advertising.
Dr. Joseph F. Sabik III, MD, has been elected as the President of The Society of Thoracic Surgeons for the 2025 term, aiming to enhance data quality, support innovative studies, and provide cutting-edge training for cardiothoracic surgeons.
A study published in European Heart Journal found that face-to-face supervised exercise programs offer the greatest benefits for patients' mental health and quality of life. Home-based programs showed more modest results, highlighting the importance of professional supervision.
Researchers document five cases of parvovirus B19-induced myocarditis in preschoolers from northern Greece, highlighting the virus's unique impact on endothelial cells. The study emphasizes the importance of quick diagnosis and treatment to reduce mortality and morbidity in children.
The American Heart Association has released its list of top cardiovascular research for 2024, focusing on prevention, treatment and the benefits of anti-obesity medications. The research highlights improvements in assessing cardiovascular risk, identifying early prevention opportunities and treating heart failure.
A systematic review and meta-analysis found CAD is common in cirrhotic patients, but cirrhosis itself may not be associated with increased CAD risk. Non-alcoholic steatohepatitis and hepatitis C virus infection are also linked to CAD presence.
A new study reveals that lung cancer screening CTs can detect coronary artery disease in 83% of cases, with high levels found in 30%. This finding highlights the potential benefits of lung cancer screening for identifying and managing cardiovascular risk factors.
Researchers found that ablation reduced ICD shocks for ventricular tachycardia and episodes of VT not detected by the ICD. This minimally invasive procedure destroys abnormal heart tissue causing VT, offering a better alternative to long-term medication side effects.
A new scientific statement highlights improvements in diagnosis, initial treatment, and long-term management of patients with Kawasaki Disease, emphasizing the need for tailored management strategies. Advances in cardiac imaging techniques and risk categorization have led to better patient outcomes.
A new hourglass-shaped stent could improve blood flow and alleviate severe chest pain in people with microvascular disease. The study found that 76% of participants experienced improvement in their daily activities, including walking and climbing stairs without pain.
A new study suggests that adding physical activity into daily life can help lower blood pressure. Replacing sedentary behaviors with 20-27 minutes of exercise per day was estimated to lead to a clinically meaningful reduction in blood pressure, while just five minutes of activity a day was also associated with reduced levels.
Cardiovascular diseases like heart failure and atrial fibrillation are linked to cognitive impairment and increased risk of dementia. Adopting a healthy lifestyle and identifying vascular risk factors early may help preserve brain function and reduce the burden of Alzheimer's disease.
A history of COVID-19 can double the risk of heart attack, stroke or death for up to three years after diagnosis. Genetic analysis revealed individuals with non-O blood types were twice as likely to experience cardiovascular events.
The conference will feature comprehensive coverage of various topics in cardiovascular medicine, including can't-miss sessions. ACC Middle East chapter teams will also compete in the ACC FIT Jeopardy competition.
A study published in JACC demonstrates that subclinical atherosclerosis burden and progression independently predict death from any cause. Asymptomatic individuals with high carotid plaque burden and coronary artery calcification are at increased risk of mortality.
A new study published in the Journal of the American College of Cardiology found that subclinical atherosclerosis is independently associated with the risk of dying from any cause. The study also showed that monitoring the progression of atherosclerosis can improve the prediction and prevention of death from any cause.
The 2024 guideline provides comprehensive recommendations for assessing cardiovascular disease risk and managing patients taking SGLT2-inhibitors. It also highlights the importance of judicious screening and evidence-based management of cardiovascular conditions before, during, and after noncardiac surgery.
A new study found that up to 10 million people in the US could qualify for Medicare-covered semaglutide injections, depending on their level of cardiovascular risk. Those with higher risk scores would be eligible for full or partial coverage, potentially expanding access to this life-saving medication.
A new study finds that four unhealthy behaviors, including smoking and physical inactivity, contribute significantly to socioeconomic disparities in coronary artery disease mortality. The researchers conclude that targeted public health policies can help reduce these disparities and improve heart health for low-income individuals.
Researchers identified changes in the UBR4 gene as a key driver of fibromuscular dysplasia, a blood vessel disorder affecting up to five percent of adults. The discovery could lead to therapeutic approaches for the condition, particularly beneficial for women who account for 90% of cases.
Research explores relationship between cardiac metabolism dysfunction and heart failure in the elderly, revealing potential therapeutic targets for improved cardiac outcomes. The study highlights the critical role of Pdk4 and MIF in cardiac metabolism, suggesting innovative treatments to manage interconnected cardiovascular conditions.
The new guidelines emphasize the importance of detecting non-obstructive coronary artery disease (NOCA/INOCA) caused by microcirculation dysfunction. A risk factor-weighted clinical likelihood model helps estimate pre-test likelihood, allowing for targeted testing and treatment. The guidelines also recommend invasive coronary functiona...
High levels of lipoprotein (a) found in 20-34% of Polish patients with heart disease or at risk. Lp(a) measurements may be crucial in preventing cardiovascular diseases and atherosclerosis progression.
Researchers at Edith Cowan University have uncovered a significant genetic connection between Alzheimer's disease and several coronary artery disease-related disorders, offering opportunities to improve health outcomes. The study found that some of the same genes played a role in or are associated across these conditions.
A study by Michigan Medicine found that older women over 65 who require complex heart surgery are more likely to be treated at low-quality hospitals, where they also die in greater numbers. The sex disparity in mortality doubled from high-quality to low-quality hospitals.
Black participants with greater access to green spaces had up to 35% lower odds of calcification, while those near a river had 32% lower odds. These findings highlight the potential benefits of environmental policies promoting public health and addressing racial and neighborhood-related health disparities.
Researchers used an advanced AI tool to identify rare coding variants in 17 genes linked to coronary artery disease, shedding light on its molecular basis. The findings could lead to novel risk identification and treatment targets for cardiovascular care.
A laboratory study found that passive heat exposure stresses the heart, increasing myocardial blood flow in all participants, regardless of age or health status. Adults with a history of CAD are at particular risk and may benefit from minimizing cardiac strain during extreme heat by staying cool.
Research from the University of Illinois has found a link between per- and polyfluoroalkyl substances (PFAS) and cardiovascular diseases in postmenopausal women. The study reveals how PFAS chemicals interact with pro-inflammatory pathways, providing potential explanations for the increased risk.
Researchers used facial thermal imaging and AI to accurately predict coronary artery disease in a study of 460 people. The approach was found to be more effective than conventional methods, identifying traditional risk factors such as high cholesterol and smoking.
Research finds insulin levels correlate with triglycerides, ApoB, non-HDL cholesterol, and free cholesterol in women with atherosclerotic coronary disease. The study suggests these laboratory-associated flags indicate early coronary atherosclerosis in both diabetic and non-diabetic women.
A Danish-Spanish collaboration is launching the REACT initiative to develop early detection and prevention methods for atherosclerosis. The project aims to identify new means to detect atherosclerosis at earlier stages and at a younger age, enabling precision treatment and prevention.
The 2024 AHA/ACC Guideline on the Management of Lower Extremity Peripheral Artery Disease aims to improve patient outcomes by emphasizing timely diagnosis and treatment. Coordinated care among a multispecialty team is crucial in reducing the risk of amputation, heart attack, stroke, and death for individuals with PAD.
Researchers have discovered a protein marker to help identify cells able to repopulate in patients with damaged blood vessels. These cells could form new blood vessels and contribute to the repair of heart tissue after a heart attack.
Randles developed computational tools to harness supercomputers, creating highly precise simulations of biophysical processes. Her work has direct impacts on patient care, including simulations of 700,000 heartbeats and cancer cells moving through the body.
Researchers at Weill Cornell Medicine have discovered a way to boost protective effects of sphingolipids in blood vessels, slowing the development and progression of coronary artery disease. The study suggests revising current views on ceramides' role in the disease, instead finding that their levels remain stable in endothelial cells.
A new study published in the Journal of the American Heart Association suggests that treating gum disease after a heart rhythm ablation procedure can lower oral inflammation and reduce the risk of AFib recurrence. Researchers found that an index measuring the severity of gum inflammation was associated with the return of AFib, highligh...
A new study published in New England Journal of Medicine found that preventive angioplasty for heart attack patients does not improve prognosis. The research included 1542 patients and showed no difference between treatment groups in terms of new heart attacks or all-cause deaths.
A recent study has found increased coronary vessel wall thickness in asymptomatic individuals living with HIV, which is significantly associated with impaired diastolic function. The study also highlights the impact of HIV on developing subclinical coronary artery disease and its effects on heart function.
A large study found that drinking more than one drink per day can increase the risk of coronary heart disease, especially among young to middle-aged women. The risk was highest among those who engaged in binge drinking, with women facing a 68% higher risk compared to moderate drinkers.
Researchers found that nontraditional stroke risk factors like migraines are as important as traditional risk factors like high blood pressure for adults younger than ages 35-45. The association between stroke and nontraditional stroke risk factors was stronger in adults younger than 35 years old.
Researchers discovered changes to blood vessels in the brain that can increase stroke and dementia risk are common in people with heart conditions. The study confirms heart disease as a main cause of these changes, highlighting the importance of imaging tests to guide safer treatment choices.