A recent study published in the Journal of Thoracic Oncology found that lung cancer clinical trials funded by the pharmaceutical industry demonstrate no more bias compared to studies funded by other sources. The analysis, led by Dr. Pedro Aguiar, assessed 477 studies and found that pharmaceutical-backed trials had stronger evidence, ev...
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateMar 25, 2020
Researchers at NYU Abu Dhabi have developed a microfluidic platform that allows for the isolation and study of circulating tumor cells (CTCs) from blood samples. The platform enables high precision analysis of CTCs' mechanical properties at the single cell level, holding potential for early cancer detection and monitoring.
SourceNew York University·JournalMicrosystems & Nanoengineering·DateMar 23, 2020
Research finds that people with a history of cancer are at over two-fold risk of developing atrial fibrillation (AFib), a heart rhythm disorder. Prostate cancer is most strongly associated with AFib, followed by colon, lung and breast cancers.
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A UK study emphasizes the significance of spirometry in identifying chronic obstructive pulmonary disease (COPD), particularly among patients with respiratory symptoms. The study found that over-reliance on radiological changes alone may lead to incorrect diagnoses, highlighting the need for comprehensive assessments.
SourceAmerican Thoracic Society·JournalAnnals of the American Thoracic Society·DateMar 13, 2020
A University of Colorado Cancer Center study found that African American patients were half as likely as non-Hispanic whites to receive PET-CT imaging for non-small cell lung cancer, while Hispanics received it 70% as frequently. This disparity may be due to limited access to specialized imaging equipment and unconscious bias.
SourceUniversity of Colorado Anschutz Medical Campus·JournalJNCI Journal of the National Cancer Institute·DateMar 11, 2020
A study found that low-dose chest CT scans used for lung cancer screening do not cause significant DNA damage or chromosome aberrations. The results suggest that the risks of low-dose CT are minimal, and it can be used for lung cancer screening.
SourceRadiological Society of North America·JournalRadiology·DateMar 10, 2020
Including smoking cessation with existing lung cancer screening efforts would significantly reduce lung cancer mortality and increase life-years gained. The study found that point-of-screening cessation interventions could further reduce lung cancer deaths by 14% and increase life-years gained by 81%.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateMar 9, 2020
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A study has described the pathology of SARS-CoV-2, or COVID-19, for the first time in its early phase. The research reveals edema, proteinaceous exudate, and inflammatory cellular infiltration in patients with COVID-19 pneumonina.
SourceInternational Association for the Study of Lung Cancer·JournalJournal of Thoracic Oncology·DateFeb 27, 2020
Researchers at University of Pennsylvania developed a blood test that correlates tumor mutations with clinical outcomes. Patients with higher mutation rates experience better responses to PD-1-based immunotherapy and longer survival times.
SourceUniversity of Pennsylvania School of Medicine·JournalClinical Cancer Research·DateFeb 26, 2020
Researchers have identified two leukemia drugs that could be used to treat lung cancer patients with triple mutant EGFR, a type of non-small cell lung cancer. The drugs, gilteritinib and midostaurin, were found using a new live cell-based method developed by the University of Toronto team.
SourceUniversity of Toronto·JournalNature Chemical Biology·DateFeb 24, 2020
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Researchers at Yale Cancer Center discovered that a small amount of the PD-L1 biomarker can predict long-term survival benefits from using pembrolizumab in patients with advanced lung cancer. The study found that overall survival was about 99% one year after discontinuing treatment, and ranged from 23% to 35% three years after treatment.
SourceYale University·JournalJournal of Clinical Oncology·DateFeb 20, 2020
A team of researchers has identified new biomarkers for the diagnosis and prognosis of lung cancer by analyzing repetitive DNA regions. These markers show consistent expression in both healthy cells and cancerous tumors, with potential applications for more accurate diagnoses and treatments.
A study of over 925,000 adults with new cancer diagnoses found that Medicaid expansion improved insurance status, led to earlier cancer stage detection, and resulted in timely treatment. The findings suggest a positive association between Medicaid expansion and cancer care outcomes.
SourceJAMA Network·JournalJAMA Network Open·DateFeb 19, 2020
Researchers identified a molecule that maintains a healthy balance of airway basal stem cells and mature mucociliary cells, potentially leading to new treatments for lung cancer. The compound, Wnt Inhibitor Compound 1 (WIC1), has been shown to limit the proliferation of basal stem cells and restore balance in human cells.
SourceUniversity of California - Los Angeles Health Sciences·JournalCell Reports·DateFeb 18, 2020
Thoracic radiation therapy increases fatigue and difficulty breathing in cancer patients, but engaging in physical activity prior to treatment may help improve these symptoms over time. High levels of physical activity are associated with concurrent improvements in fatigue and shortness of breath.
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Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers discovered that combining alectinib with EGFR-inhibitors prevents CNS metastasis progression in mouse model. This combination treatment overcomes alectinib resistance, offering potential novel therapies for NSCLC and secondary cancers.
SourceKanazawa University·JournalJournal of Thoracic Oncology·DateFeb 7, 2020
A Phase 2 clinical trial demonstrated improved localization and complete removal of small and peripheral lesions in 12% of patients. The treatment, OTL38, targets adenocarcinomas of the lung and has received fast-track designation for both lung and ovarian cancer indications.
Researchers at USC have developed a new imaging technique called spectrally encoded enhanced representations (SEER) that provides greater clarity and works up to 67 times faster than existing methods. This technology has the potential to revolutionize disease diagnosis, particularly in detecting lung cancer and damage from pollutants.
SourceUniversity of Southern California·JournalNature Communications·DateFeb 5, 2020
A recent study across 40 countries found higher lung cancer rates in young women compared to men, driven by a rise in adenocarcinoma. Historically, lung cancer was more prevalent among men due to earlier smoking habits, but the gap is narrowing in some regions.
SourceWiley·JournalInternational Journal of Cancer·DateFeb 5, 2020
Researchers found niche mutations to have higher mortality than EGFR, but similar mortality to KRAS mutations. Next-generation sequencing helps identify a large panel of mutations for precise treatment selection.
SourceImpact Journals LLC·JournalOncotarget·DateFeb 4, 2020
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A study by the University of Texas M. D. Anderson Cancer Center shows that a lung cancer screening decision aid delivered through tobacco quitlines effectively reaches a screening-eligible population and results in informed decisions about lung cancer screening. The decision aid, which explains eligibility, risks, and benefits, encoura...
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalJAMA Network Open·DateJan 31, 2020
A study found that people who quit smoking have more genetically healthy lung cells than current smokers, with a lower risk of developing into cancer. These 'protective cells' can help protect against lung cancer and may even allow new, healthy cells to actively replenish the lining of airways.
Chronic exposure to interleukin-1-beta promotes lung cancer metastasis by altering gene expression, enabling cancer cells to adopt a phenotype that facilitates distance organ colonization. The study provides new insights into the role of chronic inflammation in tumor progression and metastasis.
SourceUniversity of California - Los Angeles Health Sciences·JournalScientific Reports·DateJan 29, 2020
A study published in the British Journal of General Practice found an increase in shortness of breath and cough as the first symptoms reported by patients diagnosed with lung cancer. This suggests earlier detection, possibly due to awareness campaigns.
SourceUniversity of Exeter·JournalBritish Journal of General Practice·DateJan 27, 2020
A new tumor-highlighting technology called OTL38 enhances the visualization of lung cancer tissue, improving patient outcomes. Researchers found that OTL38 helped identify 10 additional cancers in 7 patients and improved margins for 26% of patients.
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Researchers have discovered that inhibiting p38 reduces the growth of lung tumors in genetic mouse models. Lower levels of p38 in tumors are associated with a more favorable prognosis for patients.
SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalProceedings of the National Academy of Sciences·DateJan 23, 2020
The American Cancer Society's annual report on cancer rates and trends shows a steady 26-year decline in overall cancer mortality, with long-term drops in lung, colorectal, breast, and prostate cancers. Lung cancer death rates have dropped by 51% since 1990, with the most rapid progress in recent years.
Restoring p53 using synthetic mRNA nanoparticles delays the growth of lung and liver cancer cells and makes them susceptible to available cancer drugs. The approach may also make tumors more vulnerable to cancer drugs known as mTOR inhibitors.
SourceBrigham and Women's Hospital·JournalScience Translational Medicine·DateDec 23, 2019
A University of Kentucky-led coalition is partnering with employers to connect men in rural Kentucky with critical lung cancer prevention and control resources. The worksite intervention targets predominantly male employees in eight rural counties, providing tobacco treatment, lung cancer screenings, and smoke-free workplace policies.
The study found that higher doses of radiation and adding the drug cetuximab did not improve patient survival compared to standard of care chemoradiation. The 5-year overall survival estimate for the standard radiation dose arm was 32.1%, amongst the highest for Stage III NSCLC.
SourceNRG Oncology·JournalJournal of Clinical Oncology·DateDec 16, 2019
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
The pooled analysis of three clinical trials shows entrectinib is effective in 77% of patients with ROS1+ NSCLC and 57% of patients with NTRK+ NSCLC, with significant response rates and progression-free survival times. Entrectinib's ability to penetrate brain metastases makes it a promising treatment for these patients.
SourceUniversity of Colorado Anschutz Medical Campus·JournalThe Lancet Oncology·DateDec 13, 2019
A community-based program enables patients to donate tumor tissue and blood samples for research, allowing researchers to study genetic and molecular makeup of tumors after treatment failure. Analysis reveals similar DNA mutations and varying protein biomarker expression among samples from the same patient.
SourceH. Lee Moffitt Cancer Center & Research Institute·JournalCancer Medicine·DateDec 13, 2019
Researchers identified novel respiratory cell changes in smokers and pre-cancerous tissue, which may lead to new therapies for lung cancer prevention. The study used single-cell genomics to analyze gene expression in cells from never and current smokers.
SourceBoston University School of Medicine·JournalScience Advances·DateDec 11, 2019
A new study found wide variations in surgery rates for early-stage lung cancer across US counties, with socioeconomic and healthcare delivery factors contributing to the gap. Counties with higher poverty rates, non-Hispanic black populations, and lower surgeon-to-population ratios had lower surgery rates.
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
A new study found that depression affects approximately one-third of newly diagnosed lung cancer patients, leading to severe symptoms such as pain, hopelessness, and impaired day-to-day functioning.
SourceOhio State University·JournalLung Cancer·DateDec 4, 2019
A study found that AI can accurately measure coronary artery calcium, a marker of heart disease, in patients getting lung cancer screening CT scans. The system uses deep learning to automate the assessment, making it easier for doctors to decide on preventative therapy.
SourceRadiological Society of North America·DateDec 3, 2019
Researchers at UT MD Anderson Cancer Center found TBK1 and its adaptor protein contribute to tumorigenesis when activated by growth factors. Targeting TBK1 inhibits tumor growth and promotes antitumor immunity in mouse models.
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalNature Cell Biology·DateDec 2, 2019
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers have found that anti-cancer agents with low-molecular weights cannot reach tumors effectively due to obstructed small arteries. This limits the use of conventional chemotherapy and highlights the need for new treatments, according to Professor Tetsuya Kodama.
SourceTohoku University·JournalScientific Reports·DateNov 27, 2019
Researchers developed nanoparticles that can deliver immunostimulants via inhalation to induce systemic immune response against lung cancer. The treatment converted cold tumors to hot, immune-responsive tumors and showed significant regression of tumors in both lungs and prolonged survival of mice.
SourceAtrium Health Wake Forest Baptist·JournalNature Communications·DateNov 14, 2019
Researchers aim to reduce malnutrition among lung cancer patients by providing nutritional counseling and medically tailored meals. The study, funded by Bristol-Myers Squibb Foundation, will recruit up to 150 newly diagnosed patients with lung cancer across four medical centers.
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A deep convolutional neural network-based software improved radiologist detection of malignant lung nodules by 70.3%, reducing false positives to 0.18 per X-ray. The study suggests machine learning methods can help overcome challenges in detecting lung lesions on chest X-rays.
SourceRadiological Society of North America·JournalRadiology·DateNov 12, 2019
Researchers at Stanford and UC-San Francisco have developed an experimental drug that targets lung cancer by neutralizing a single protein, slowing its growth. The decoy version of the receptor protein was engineered to preferentially bind to the protein, repelling other proteins involved in tumor growth.
SourceStanford Medicine·JournalNature Medicine·DateNov 7, 2019
The American College of Physicians (ACP) has released a new guidance statement for colorectal cancer screening in average-risk adults between 50 and 75 years old. The guidance suggests that physicians select the most suitable screening test for each patient based on factors such as benefits, harms, costs, availability, frequency, and p...
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateNov 4, 2019
Researchers analyzed BTB and BBB changes in NSCLC brain metastasis over time, revealing key changes including loss of aquaporin-4 and zona occludens-1. These findings provide a comprehensive analysis of the transition of the blood-brain barrier to the blood-tumor barrier.
SourceImpact Journals LLC·JournalOncotarget·DateOct 31, 2019
A high-fiber and yogurt-rich diet has been shown to reduce lung cancer risk by 33% compared to a low-fiber diet. The study's findings support the US Dietary Guidelines recommending a high fiber and yogurt diet for cardiovascular health and gastrointestinal cancer prevention.
SourceVanderbilt University Medical Center·JournalJAMA Oncology·DateOct 25, 2019
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
A study of over 14,000 participants found associations between specific cigarette characteristics and lung cancer outcomes. Researchers analyzed data from a lung screening trial to investigate the impact of cigarette filter status, tar level, and menthol flavor on lung cancer outcomes.
SourceJAMA Network·JournalJAMA Internal Medicine·DateOct 21, 2019
Screening for ever-smokers with high lung cancer risk and long life-expectancy can prevent more deaths than current guidelines. A new study suggests using gains in life expectancy as a criterion to select candidates for screening, which could improve the balance of benefits and harms.
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateOct 21, 2019
A new study presented at the IASLC 2019 North America Conference on Lung Cancer found that lung cancer screening guidelines are inadequate to diagnose patients who contract lung cancer from occupational exposure, including first responders. Low-dose computed tomography was shown to detect disease earlier in this population.
SourceInternational Association for the Study of Lung Cancer·DateOct 11, 2019
Researchers have discovered that patients' blood samples and tumour biopsies can reveal early signs of lung cancer spreading and becoming untreatable. The TRACERx project has identified possible causes of recurrence and developed new techniques to predict tumour aggression.
SourceCancer Research UK·JournalNature Medicine·DateOct 7, 2019
A study has identified key proteins in signaling pathways that control tumor growth in lung tissue, paving the way for personalized cancer treatment and new drug development. The research, published in Cell, also reveals new proteins activated by cancer mutations contributing to tumor growth.
SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalCell·DateOct 3, 2019
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
A 40-year epidemiological study found that cancer incidence and mortality rates often move in concert for certain cancers, such as lung cancer, indicating a desirable trend. However, other cancers like thyroid, kidney, and melanoma show rising incidence rates with stagnant mortality rates, suggesting overdiagnosis may be at play
SourceBrigham and Women's Hospital·JournalNew England Journal of Medicine·DateOct 2, 2019
The breast cancer death rate has slowed in recent years, but the gap between black and white women remains significant. Breast cancer incidence rates have continued to rise, with a greater increase seen in hormone receptor-positive disease.
Researchers found that adding durvalumab to radiation and chemotherapy significantly decreased the recurrence of lung cancer in both chest and distant sites, with new lesions occurring primarily in the brain. This suggests that aggressive local therapies may further extend survival for patients with non-small cell lung cancer.
SourceAmerican Society for Radiation Oncology·DateSep 26, 2019
A phase II trial found that adding radiation therapy to immunotherapy increases progression-free survival for patients with metastatic non-small-cell lung cancer. T cells played a key role in the immune response, with certain markers predicting longer disease-free periods.
SourceAmerican Society for Radiation Oncology·DateSep 26, 2019
Researchers at Medical College of Georgia have found a link between high levels of TIMP-1 and IL-6, two molecules that contribute to chemotherapy resistance in non-small cell lung cancer. The study's findings suggest that elevated levels of these molecules may be an indicator of poor prognosis and a potential target for improving treat...
SourceMedical College of Georgia at Augusta University·JournalCancers·DateSep 20, 2019
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
A study by VA Portland Health Care System and Oregon Health and Science University researchers found that early palliative care can increase survival in patients with advanced lung cancer. The study analyzed data on over 23,000 veterans and showed that palliative care provided shortly after diagnosis can lead to improved survival rates.
SourceVeterans Affairs Research Communications·JournalJAMA Oncology·DateSep 19, 2019
A new electronic nose can identify lung cancer patients who will respond to immunotherapy with 85% accuracy, outperforming the current gold standard of immunohistochemistry. The non-invasive test detects chemicals in patient breath and provides instant feedback, potentially avoiding ineffective treatment and side effects.
SourceEuropean Society for Medical Oncology·JournalAnnals of Oncology·DateSep 17, 2019
Scientists have identified distinctive characteristics of KRAS-positive lung cancers that can be targeted to inhibit growth, offering a new approach for personalized therapy. The study suggests exploring co-existing mutations as an alternative to traditional therapies.
SourceWalter and Eliza Hall Institute·JournalNature Communications·DateSep 13, 2019
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Markey researchers identify nuclear glycogen's role in cancer progression and find epigenetic connections between glycogen metabolism and gene expression. The study reveals new therapeutic targets to treat non-small cell lung cancers.
SourceUniversity of Kentucky·JournalCell Metabolism·DateSep 12, 2019
Researchers developed a new classification method using artificial intelligence to identify primary cancerous tissue in head and neck cancers. The method achieved an accuracy of over 99% in distinguishing between primary lung squamous cell carcinomas and head and neck metastases, offering potential benefits for patients.
SourceCharité - Universitätsmedizin Berlin·JournalScience Translational Medicine·DateSep 12, 2019