Articles tagged with Seizures
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Scientists at UNC School of Medicine discovered that replacing the faulty UBE3A gene in children's brains can prevent seizures, but not in adults. The study suggests a window of opportunity for prevention between early childhood and adulthood.
A recent study published in Pediatric Research found that children who received wishes were 2.5 times more likely to have fewer unplanned hospital admissions and 1.9 times less likely to use the emergency department. This led to a decline in healthcare costs, even after accounting for the average cost of the wish.
A new high-tech bracelet, Nightwatch, detects 85% of all severe night-time epilepsy seizures and can save thousands of lives. The device recognizes key characteristics of severe attacks and sends wireless alerts to carers or nurses.
A 2018 study from Nova Scotia found that seizures of illicit cigarettes decreased significantly between 2007-08 and 2017-18, with no statistically significant increase after the 2015 menthol ban. The prevalence of illegal tobacco in the province also decreased from 30% to less than 10%.
A comprehensive epidemiological study published in Neurology reveals that women with epilepsy are at a significantly increased risk of mortality during pregnancy. Despite the small absolute risk, the probability must be multiplied by five, making pregnant women with epilepsy a critical group to follow closer.
The study uses genetic matching and port data to identify the three largest cartels involved in African elephant ivory trade. The researchers hope their findings can help police this illegal trade and strengthen ongoing cases against particular cartels.
Researchers linked 11 large ivory shipments to the same networks using DNA testing, revealing connections between isolated seizures and identifying key trafficking hubs. This breakthrough helps officials track and build evidence against those responsible for the bulk of illegal ivory trade.
Researchers identified a neuronal BRAF somatic mutation causing intrinsic epileptogenicity in pediatric brain tumors, leading to a potential new therapeutic target. The mutation arose from neural stem cells and was found to alleviate seizures in animal models treated with the BRAF inhibitor Vemurafenib.
A study of over 1,000 patients with epilepsy found that seizures are linked to natural rhythms in around 80% of cases, with most occurring in a circadian rhythm. Weekly and longer cycles were also detected, with two-thirds of people having multiple types of cycles associated with their seizures.
Researchers have successfully implanted a device in mice brains to detect, stop and prevent epileptic seizures. The device uses a neurotransmitter to signal to neurons to stop firing, effectively ending the seizure. Early results show promising potential for treating conditions like Parkinson's disease and brain tumors.
A team of researchers at University of Alabama at Birmingham has identified a sentinel area of the brain that may give an early warning before clinical seizure manifestations appear. An algorithm was also developed to automatically detect this early warning, allowing for neurostimulation of the sentinel area to potentially block seizures.
Researchers have developed high-tech tools to identify the genetic cause of early childhood seizures, a rare disease that can lead to intellectual impairment and early death. The new approach uses computational tools to analyze genetic data and pinpoint changes in the genome responsible for disease development.
A study by University of Melbourne researchers reveals that clinically relevant epileptic seizure prediction is possible in a wider range of patients than previously thought. The crowdsourcing of over 10,000 algorithms worldwide led to an average 90% improvement in seizure prediction performance compared to previous results.
Researchers found that the left hemisphere of the boy's brain compensated for visual tasks, but he couldn't see the left half of the world. Despite losing parts of his visual system, UD performed normally on pattern perception and had age-appropriate intellect and language skills.
A study published in Cell Reports found that a child's brain can reorganize its visual system after losing parts of the visual cortex. The child, UD, had nearly half of his right hemisphere removed due to epilepsy, but his brain compensated by using the intact left hemisphere for tasks like facial recognition and object analysis.
For adults with non-index seizures, ED neuroimaging is associated with a 3% change in patient management. Clinical factors like acute head trauma, prolonged consciousness, and focal neurological examination increase the yield of imaging tests.
Two full-term newborns with ruptured myelomeningoceles developed multi-resistant Acinetobacter baumannii meningitis. They were treated with intravenous colistin, resulting in favorable outcomes. The cases highlight the challenges of treating hospital-acquired infections in neonates.
Researchers developed a mouse model to investigate the potential long-term symptoms of congenital Zika virus infection, finding weight loss, cognitive deficits, and impaired motor function. Infliximab, a TNF-α inhibitor, showed promise in reducing seizures in young mice, offering new hope for public health crisis
Infected mice developed seizures, motor function impairment, and memory issues as adults, with reduced muscle strength and increased inflammation. Targeting TNF-α inhibition may alleviate some long-term consequences of neonatal Zika infection.
A Penn Medicine study reveals that early-life seizures can lead to premature activation of synapses tied to learning and language skills in children with autism. The researchers found that an antiepileptic drug may keep these synapses 'silent' longer, allowing the brain to develop normally.
Researchers at the University of Sydney have developed a generalized method to predict epileptic seizures using data from non-surgical devices powered by AI and machine learning. The system can alert epilepsy sufferers within 30 minutes of the likelihood of a seizure, with an accuracy rate of up to 81.4%.
Researchers found that the ketogenic diet alters gut microbiota in mice, leading to reduced seizures. Specifically, two types of bacteria - Akkermansia muciniphila and Parabacteroides species - play a key role in providing protection against seizures.
A new study found that cannabidiol significantly reduces seizures in patients with Lennox-Gastaut syndrome, a rare and severe form of epilepsy. The trial showed a 41.9% reduction in drop seizures for the 20 mg/kg/d CBD regimen, highlighting the potential effectiveness of Epidiolex as an treatment option.
Researchers at the University of Kentucky have discovered a potential target for treating epilepsy seizures: cPLA2, an enzyme that contributes to blood-brain barrier dysfunction. Blocking this enzyme may prevent changes in barrier leakage, offering new hope for patients who do not respond well to current medications.
Researchers discover urethane, a compound formed during beer and wine fermentation, is more effective at combating seizures caused by organophosphate nerve agents than the current recommended treatment. The study suggests urethane or its derivative may prevent seizures from developing into epilepsy.
Researchers at Lund University discovered a new approach to treat severe epilepsy by targeting a specific brain area, reducing seizure activity. This breakthrough method, using chemogenetics, may pave the way for improved treatment options for thousands of people in Sweden affected by the disease.
Researchers identified a seizure-triggered pathway that contributes to blood-brain barrier dysfunction in epilepsy. Blocking the activity of an enzyme called cytosolic phospholipase A2 (cPLA2) prevented capillary leakage and associated changes.
A new brain stethoscope technology has been developed that translates brain electrical activity into sounds, allowing medical professionals to detect silent seizures. Medical students and nurses were found to be remarkably accurate in identifying seizures with this tool, outperforming their traditional diagnostic abilities.
Researchers developed a novel method to detect ongoing seizures in comatose patients using brain waves converted to sound. The sonification of EEG provides a potential tool for quickly assessing patients with suspected subclinical seizures like nonconvulsive status epilepticus.
Researchers at Syracuse University have identified a key protein and enzyme involved in regulating seizures, finding that T-cell intracellular antigen-1 (TIA-1) suppresses severe electrical storms in the brain by increasing cyclooxygenase-2 (COX-2) expression in neurons.
A review of available evidence suggests that cannabis compound cannabidiol (CBD) may curb the frequency of epileptic seizures, particularly in children and teens with rare and severe forms of epilepsy. CBD was found to be more effective than a placebo at reducing seizure frequency by 50% or more, and improving quality of life.
The University of Cincinnati has received a $1.75 million grant to study signaling pathways underlying the development of acquired epilepsy. Researchers aim to prevent seizures without side effects, addressing a pressing need in epilepsy treatment.
A new study published in Science suggests that loss of mossy cells plays a critical role in both convulsive seizures and memory problems associated with temporal lobe epilepsy. In a mouse model, researchers found that turning on mossy cells prevented seizures from transitioning into convulsions.
Researchers at Stanford University School of Medicine discovered that a specific set of nerve cells, known as mossy cells, controls the spread of seizures throughout the brain. Inactivating these cells facilitates the spread of electrical hyperactivity, leading to full-blown behavioral symptoms of temporal lobe epilepsy.
A recent study found that learning stress-reducing techniques can significantly reduce the frequency of seizures in people with difficult-to-treat epilepsy. Participants who learned progressive muscle relaxation and breathing techniques experienced a 29% decrease in seizures, while those in the control group had a 25% reduction.
A University of Houston biomedical engineer has developed a new method to locate the brain's seizure onset zone in record time, reducing hospitalization time from up to 10 days to just one hour. This breakthrough could save patients weeks of treatment and improve their quality of life.
A phase 3 clinical trial found that cannabidiol reduced the number of drop seizures in patients with Lennox-Gastaut syndrome by 43.9% compared to placebo. However, long-term efficacy and safety concerns remain to be confirmed.
A large-scale study found subtle brain abnormalities in people with epilepsy, even in those with typical seizures under control. The researchers identified reduced grey matter thickness and volume in various brain regions, including the cortex and thalamus, associated with longer duration of epilepsy.
A new study suggests a shared genetic susceptibility between epilepsy and mood disorders, particularly in individuals with focal epilepsy. The study found a significant increase in lifetime prevalence of mood disorders among people with focal epilepsy compared to those with generalized epilepsy.
Researchers developed a probabilistic modeling approach using artificial intelligence techniques to predict seizure-generating brain regions from non-seizure data. This could significantly improve the accuracy and reduce the time needed for identifying these regions, potentially transforming the field of epilepsy surgery.
A small pilot study found one sign of CTE in a younger person with epilepsy, but no unique characteristics compared to other participants. Researchers suggest that tau protein deposits may not contribute to cognitive impairment in young patients with localized seizures.
Researchers found a possible genetic connection between seizures and mood disorders like depression in people with focal epilepsy, which may improve quality of life. Mood disorders were not linked to generalized epilepsy.
Researchers at UCSF have discovered monthly cycles of brain activity linked to seizures in patients with epilepsy. By analyzing data from implanted brain stimulation devices, the team identified patterns of electrical discharges known as 'brain irritability' that are associated with higher seizure risk.
Experts warn of a significant peak in chocolate poisoning risk for dogs during Christmas and Easter, due to increased accessibility of festive treats. Researchers analyzed 386 cases of dog intoxication from UK veterinary practices between 2012-2017, finding vomiting, heart rate increases, and agitation were common symptoms.
A study published in The Lancet Child and Adolescent Health found that prolonged convulsive seizures in childhood can lead to lasting neurological conditions, including epilepsy, learning disabilities, and movement problems. Children with pre-existing neurological issues were more likely to experience chronic problems after a seizure.
Fetal monitoring specialists argue that continuous electronic monitoring is associated with lower infant mortality and should be used for all women in labor. However, other experts claim that the practice increases intervention rates and may not prevent neonatal deaths, suggesting a reevaluation of its benefits.
Researchers analyze order flow for pairs of NASDAQ 100 stocks and find four groups with large mutual differences, surprising given the lack of reflection in actual prices. This discovery contributes to modeling price evolution and could be used to evaluate the impact of financial crises.
Researchers at RUDN University have developed a chemical compound with anticonvulsant properties, showing effectiveness only when it is chirally pure. The compound was synthesized and studied to create an efficient and usable drug for treating epilepsy.
Researchers at Aarhus University have found a hormonal link to unexplained seizures in women, revealing a biological cause for the previously psychologically attributed condition. The study measured hormone levels in patients with psychogenic non-epileptic seizures (PNES) and found lower neuropeptide Y levels, associated with stress re...
New research published in Epilepsia indicates that wristband devices can improve the detection and characterization of seizures in patients with epilepsy. The devices detected 95% of seizures while keeping false alarm rates at a bearable level, providing real-time alerts to caregivers and improving patients' quality of life.
A multi-site study will investigate whether cognitive behavior therapy can reduce seizure frequency and severity in individuals with traumatic brain injury. The study aims to shed light on the mechanism behind post-traumatic epilepsy and psychogenic nonepileptic seizures.
A systematic review found only two pediatric uses of medical cannabis to be supported by existing studies: reducing seizures and chemotherapy-induced nausea and vomiting. The research highlights the need for more comprehensive studies to understand the effectiveness and risks of medical cannabis in children and adolescents.
Researchers discover how seizures trigger cognitive deficits in Alzheimer's disease through increased levels of the protein deltaFosB, leading to suppressed production of calbindin and disrupted brain activity. Further studies support the findings, showing potential new strategies for reducing cognitive deficits.
Researchers found that a lack of CLOCK protein is associated with excessive brain cell excitation and stronger seizures during sleep. Delivering a drug that compensates for the lack of CLOCK or its affected proteins directly in the brain may offer a new treatment approach for severe epilepsy cases.
A mouse study shows that cannabidiol treatment effectively reduces the severity and duration of seizures and their frequency. The study also found improvements in social interactions and reduced autism-like symptoms in mice with Dravet syndrome.
Researchers create a computational model to simulate focal cooling, a brain-cooling treatment that may ease epileptic seizures. The model reveals insights into the mechanism underlying this technique, which involves suppressing electrical signals in specific brain regions.
A Rutgers University study suggests that excessive neurogenesis after a traumatic head injury can lead to epileptic seizures and long-term cognitive decline. By preventing this process with a drug, the rate of brain cell birth returned to normal levels, reducing the risk of seizures.
Researchers developed a method to identify brain tissue most likely to generate seizures in people with epilepsy, offering new treatment strategies for drug-resistant cases. By analyzing EEG recordings and mathematical modeling, the team found that targeting specific brain regions could lead to enhanced surgical outcomes.
A new mathematical approach has identified brain regions that contribute most to epilepsy seizures, allowing surgeons to select specific areas for removal. The method has shown promise in reducing the number of seizures experienced by patients, providing a potential breakthrough in epilepsy treatment.
A study from Hiroshima University found that the brain's estrogen levels are directly linked to DHA intake, which can prevent seizures. The research suggests that dietary sources of DHA may contribute to brain health and could lead to the development of new epilepsy treatments.