Articles tagged with Substance Related Disorders
A new study from the University of Colorado Anschutz Medical Campus introduces a more individualized approach to restarting methadone treatment for people with opioid use disorder. The findings suggest that tailoring methadone doses to each patient's unique circumstances can improve care without compromising safety.
Among youth aged 15-24, polysubstance-involved opioid overdose deaths rose steadily with age, driven by fentanyl and synthetic opioids. By age 21, polysubstance involvement surpassed opioid-only fatalities, primarily due to stimulants like methamphetamine and cocaine.
A new guideline from the Canadian Task Force on Preventive Health Care provides a menu of effective options to help people quit smoking, including behavioural and medication options. The guideline aims to address the challenges of nicotine addiction and offers personalized choices for quitting tobacco.
Adults who quit smoking were more likely to achieve sustained remission of substance use disorder symptoms. The analysis found a 42% greater odds of recovery when quitting smoking was combined with addiction recovery efforts.
A study investigated approach/avoidance tendencies in male AUD patients through a gait initiation task, using posturography. The findings suggest that analyzing micromovements and reaction times may help predict if individuals will relapse following treatment.
The study examines the effects of broader criminal justice reforms on public health and safety. It found little evidence that Measure 110 was responsible for rising crime or overdose deaths, but rather attributed these trends to the COVID-19 pandemic and fentanyl emergence.
A UTEP study found that drinking coffee at night increases impulsive behavior in fruit flies, particularly females. The researchers discovered that caffeine consumed after dark led to reckless flying despite aversive conditions, suggesting potential negative implications for shift workers and others who consume coffee late.
A new study by Mass General Brigham found that states with flavored e-cigarette ban policies experienced a significant decline in e-cigarette use among young adults and adults, but a slower decrease in cigarette smoking rates. This mixed impact raises concerns about the unintended consequences of flavor bans.
A Rutgers-led study of nearly 12,000 youth found that genetic predispositions, brain structure, personality traits, and environmental conditions contribute to the onset and progression of adolescent alcohol use. The research highlights the importance of early interventions targeting high-risk youth.
Researchers have developed a new measurement method to accurately quantify allergy-triggering proteins (ATIs) in barley. Analyzing over 180 barley accessions from around the world, they identified ten barley-specific ATI types for the first time, revealing varying content between 1.1 and 5.2 milligrams per gram of flour.
Adults with moderate or severe substance-use symptoms have a higher chance of initiating and staying on OUD medication treatment. The study found that most primary care patients with opioid use disorder symptoms did not receive evidence-based treatment, but those who initiated treatment remained engaged.
A national study found that healthcare providers exhibit varying levels of stigma towards patients with substance use disorders (SUD), particularly for opioid and stimulant use. This stigma leads to missed opportunities for care and is often embedded in clinical encounters.
Research from UCLA Health Sciences found that individuals with substance use disorders are at a higher risk of unplanned hospital readmissions. Specifically, those with opioid use disorder had the highest 30-day readmission rates.
A new study identified key risk factors associated with non-fatal overdoses, including polysubstance use patterns, socioeconomic challenges, and lack of access to harm reduction services. The study found nearly half of participants had experienced a non-fatal overdose in their lifetime, significantly higher than previous rates.
The Be Well Texas initiative, led by the University of Texas Health Science Center at San Antonio, will expand access to opioid use disorder treatment services and recovery support across rural and urban communities. This major statewide expansion aims to reduce overdose deaths and build a lasting recovery infrastructure.
A study published in Pediatrics reveals a sharp surge in nicotine pouch ingestions among young children, with a 763% increase in rate of reported cases between 2020 and 2023. The ingestion rates for other nicotine products declined during the same period.
A randomized controlled trial found that vaporized nicotine products were more effective than nicotine replacement therapies for smoking cessation in a low socioeconomic status population. The study suggests that Vapes may have a critical role in promoting smoking abstinence among this disproportionately affected group.
A sweeping national study by ICAMH at Hebrew University found substantial increases in substance use, behavioral addictions, and mental health disorders in Israel since the October 7, 2023 attacks. Younger, secular populations were most at risk, with sociodemographic disparities evident across repeated samples.
The latest APA journal issues feature research on high-potency cannabis use, adolescent suicidal behavior, and problematic internet usage. Highlights include a systematic review of cannabis health effects in adolescents and trends in prescription stimulant and opioid use among US teens.
A study by researchers at Keck School of Medicine of USC found that teens who see cannabis or e-cigarette content on social media are more likely to start using those substances. The study, which surveyed over 7,600 California high school students, also found a link between influencer content and substance use.
A new study reveals that US Muslims show moderate openness to psychedelics in mental health therapy, with higher education correlating with favorable attitudes. Providing education about psychedelic therapies may help lower barriers to considering this treatment.
A new online toolkit developed by the University of Ottawa and Health Canada aims to educate healthcare providers on managing opioid-related issues. The toolkit's co-creation model involves patient input, leading to a deeper understanding of chronic pain and opioid use, and a more compassionate approach to care.
A new study identifies critical barriers and promising strategies to scale up low-barrier wound care services for PWUD. The research highlights the urgent need for accessible and empathetic approach to wound care, proposing practical steps to reach those who need it most.
A study of 7,944 ADHD patients found that telehealth-based relationships did not increase the risk of substance use disorder. However, patients aged 26 and above who received initial stimulant prescriptions during telehealth appointments were at higher risk.
Researchers have identified a specific group of neurons in the brain responsible for suppressing binge drinking behavior. The discovery may lead to new therapeutic targets for treating alcohol dependency and related health challenges.
A new FAU study analyzing 16 years of national data reveals the most common reasons why people with cannabis problems don't seek help, including lack of knowledge, cost, stigma, and fear of job impacts. The study also identifies consistent predictors of access to treatment, highlighting an urgent need for targeted outreach and improved...
Researchers found that ibudilast works better for women who have lower levels of depression and inflammation. The study, which recruited 102 adults with moderate or severe alcohol use disorder, showed that ibudilast did not reduce drinking in most participants, but had a positive effect on female participants.
A WVU microbiology student has discovered a new species of fungus, Periglandula clandestina, that produces effects similar to the semisynthetic drug LSD. The fungus is highly efficient at making ergot alkaloids, which can be used therapeutically to treat conditions like depression and addiction.
A recent study by UT Arlington researcher Dr. Awua found that social influences and peer pressure significantly impact substance use among young adults College students often misjudge their peers' drinking habits, leading to heavy episodic drinking and negative consequences The study suggests using protective behavioral strategies like...
A recent study by the CDC suggests that many youth-serving clinicians fail to screen for substance use disorders regularly. The findings highlight the need for improved education and practice changes to enhance screening rates.
The introduction of BC's opioid prescribing standard in 2016 led to a reduction in opioid prescriptions and doses, as well as declines in high-dose prescribing and coprescribing with benzodiazepines. However, this change also resulted in increased aggressive tapering of medications, which can lead to improper pain management.
A new paper proposes targeting domestic vape distributors with state and local lawsuits to regulate flavored e-cigarettes. The strategy could result in stiff financial penalties for lawbreakers, forcing them to stock only FDA-cleared vapes. If successful, this approach may align what's on the shelves with what's legal.
A randomized controlled trial in Switzerland found that legal access to cannabis decreases problematic consumption, especially among individuals using other substances. After two years, participants showed significant improvements in mental state.
A pilot program was conducted in South Africa to provide harm reduction and medications for opioid use disorder among people living with HIV and illicit opioid use. The study found low uptake of medication-assisted treatment after release, citing perceived ineffectiveness and delays in initiation.
A new study published in the Journal of Child Psychology and Psychiatry reveals that childhood trauma significantly increases the likelihood of engaging in risky behaviors, including harmful alcohol consumption, smoking, and illicit drug use. The research also found an unexpected connection between trauma and cardiovascular health, wit...
A new study found that about 5.4% of teens used nicotine pouches in 2024, up from 3.0% in 2023, and dual use with e-cigarettes increased. Researchers warn of potential health risks and call for tailored prevention strategies.
A new study found that both oral and injectable forms of naltrexone are effective in reducing heavy drinking among hospitalized patients. The medication was administered before discharge, resulting in a significant decrease in heavy drinking within the last 30 days of the three-month follow-up period.
A novel brain study uncovers the critical role of the HDAC5 enzyme in regulating gene expression and neuronal activity, which can trigger relapse in individuals with substance use disorders. The study highlights a new molecular target for developing novel treatments to reduce relapse risk.
Researchers at Carnegie Mellon University have developed a new, minimally invasive method called DeepFocus for treating depression and other neural conditions using transnasal electrical stimulation. This technique offers more accurate and efficient targeting of deep brain structures with lower risk.
A new study provides the first nationwide picture of who knows about, carries, and uses naloxone to reverse deadly opioid overdoses. The survey found that people's perception of overdose risk correlates with their decision to carry naloxone, and those with high-risk profiles are more likely to carry the drug.
A new study found that people seeking emergency care for hallucinogen use were at a 2.6-fold higher risk of death within 5 years compared to the general population. The increased risk was highest among individuals with medical comorbidities and those from low-income neighborhoods.
A new study in mice found that young adults are more susceptible to nicotine addiction than middle-aged adults, with a greater acute response to nicotine. The effects of nicotine on the body change over the lifespan, affecting how medications and other chemicals are processed.
A recent study by UCLA researchers has discovered high amounts of bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate (BTMPS) in illicitly sold fentanyl. BTMPS is not approved for human consumption and has been linked to serious health effects such as cardiotoxicity and ocular damage.
New research reveals a 18% increase in alcohol-related deaths in Canada during the pandemic, with higher increases in 2020 and 2021. The study also found increased hospitalizations related to alcohol use, particularly among younger adults and females, suggesting potential early warning signs for future liver-related disease.
The prevalence of substance use disorder surged during the COVID-19 pandemic, but treatment receipt declined initially due to healthcare disruptions. Treatment rates began to recover in 2022, likely driven by reopened treatment programs and increased telehealth use.
Researchers at MUSC discover an RNA:DNA 'sandwich' plays a key role in how the brain interprets emotional experiences and brings about behavioral adaptations. The discovery could lead to better RNA therapies for treating brain disorders.
Researchers at Drexel University developed an AI tool using large language models to identify and suggest alternative words that stigmatize people with substance use disorder. This framework aims to educate users and preserve supportive spaces in online forums.
The updated clinical practice guideline recommends buprenorphine and methadone as first-line treatments for patients with opioid use disorder. New research and clinical considerations have led to the removal of methadone prescribing restrictions in Canada, but opioid-related harms continue to rise.
The Appalachian Region's mortality rate from diseases of despair decreased by 4% between 2021 and 2022, while remaining virtually unchanged outside of Appalachia. However, the region still experiences higher rates of mortality from these diseases across all age groups, particularly among those in their prime working years.
Researchers found a significant increase in the use of naloxone by people without medical training to treat opioid overdoses. From June 2020 to June 2022, EMS reported 24,990 patients receiving naloxone from an untrained bystander before EMS arrived, representing a 43.5% growth.
A new study by Penn State researchers found that students who feel a sense of belonging at their university are more likely to binge drink than those who do not. The study, which analyzed data from over 4,000 university students, suggests that feeling connected to the university is associated with higher rates of substance use.
A new study found that completing a six-month substance use disorder treatment program instead of arrest and prosecution reduces the risk of arrest, incarceration, or fatal overdose. Participants who completed the program had a more favorable crime and overdose profile compared to those who did not engage or complete the program.
Research from Trinity College Dublin found that lower sustained attention in adolescence can predict a larger increase in cigarette and cannabis use by age 23. The study suggests using early biomarkers like sustained attention to identify vulnerable adolescents and guide targeted interventions.
Researchers found that serotonin release scales with the value of rewards, indicating its role in monitoring reward quality. The study used a new biosensor to measure serotonin levels in mice receiving varied concentrations of evaporated milk as rewards.
The UCR medical school is developing a new curriculum to address the substance use crisis in California, which has resulted in over 6,000 opioid-related overdose deaths. The curriculum aims to promote access to treatment and health equity for substance use care, addressing biases and social determinants of health.
A major new review of evidence has identified three top ways to stop smoking: combining behaviour support with medication like bupropion or nicotine replacement therapy. The Cochrane Tobacco Addiction Group's systematic reviews also found strong evidence for behavioural counselling and financial incentives.
A new study found that communities with pharmacies dispensing standing order naloxone experienced a gradual and significant decrease in opioid deaths, averaging 16% per year. This suggests that expanding access to naloxone through state-mandated standing orders can save lives and reduce opioid fatality rates.
A new study found that communities with pharmacies implementing a state standing order to distribute naloxone without a prescription showed a significant decrease in opioid-related deaths. The analysis, conducted from 2013 to 2018, observed a gradual decline of 16% per year in cities with naloxone distribution, compared to those without.
A North Carolina State University study found that only 12% of organizations providing residential opioid substance use services are licensed by the state. Only a quarter allow patients to access proven opioid agonist treatment (OAT), which has better outcomes and cuts overdose deaths in half.
Researchers found that women with opioid use disorder face structural barriers and stigma that may keep them from engaging with traditional harm reduction practices. Increasing accessibility of harm reduction tools and expanding education are key recommendations to reduce overdose risk for women.