Articles tagged with Disease Incidence
A new study found that women with BRCA1 or BRCA2 mutations have a cumulative risk of 49% developing any type of cancer after age 50. Risk-reducing surgeries like mastectomies and BSOs can lower this risk, but many women opt out despite elevated risk. Genetic testing is crucial for accurate risk assessment and personalized care.
A new study found that individuals with a normal gastrointestinal biopsy still have a higher risk of developing inflammatory bowel disease (IBD) in the years following the biopsy. The study of over 450,000 individuals in Sweden showed that symptoms of IBD may start significantly before the disease shows up on biopsy.
A new Stanford-led study uses satellite and land use data to predict malaria outbreaks in Madagascar, providing insights into the disease's distribution and burden. The research identifies rural areas with flooded rice fields as high-risk zones for malaria transmission.
Researchers analyzed data on European travellers arriving from Africa between 2015 and 2019, finding malaria as the most common arthropod-borne disease. The study highlights the importance of using travellers' health data to complement local surveillance systems in Africa.
A Chinese Medical Journal study analyzed the temporal and spatial distribution of epilepsy across China, finding significant increases in incidence and prevalence rates between 1990 and 2019. The study also showed a general decrease in age-standardized DALY rates with increasing socio-demographic index.
A recent study monitored the Italian province of Pescara for 18 months and found no increased risk of serious diseases among vaccinated individuals. The study revealed that vaccinated persons were more protected against COVID-19 and had lower rates of deaths and disease occurrences compared to non-vaccinated individuals.
A Rutgers study found that older people living with HIV/AIDS face unmet mental health needs and are more likely to experience PTSD, substance dependence, and suicidal thoughts. Resilience may play a crucial role in increasing adherence to antiretroviral therapy, which is essential to ending the AIDS epidemic.
A study of 57,460 US cases found a sustained decrease in infant pertussis incidence following Tdap vaccine introduction. Maternal vaccination is associated with reduced disease burden among young infants.
A new study found that women with pre-pregnancy migraine had greater risks of preterm delivery, gestational hypertension, and preeclampsia. Migraine with aura was associated with a higher risk of preeclampsia than without aura.
Researchers analyzed data from the VITAL trial and found that vitamin D supplementation increased biomarkers associated with vitamin D metabolism in people, regardless of their weight. However, these increases were significantly smaller in people with elevated BMIs, suggesting a blunted response to supplementation.
A large cohort study found that long-term low-dose hydroxychloroquine use is associated with a low risk of developing retinopathy, while higher doses increase the risk. Regular screening can identify the issue at an early stage.
Researchers from prominent institutions discuss hepatocellular carcinoma's pathogenesis, genomic heterogeneity, and targeted therapy options. The review aims to characterize HCC's complexities and develop clinically relevant biomarkers for better management.
A new software developed by researchers at Cold Spring Harbor Laboratory can accurately infers continental ancestry from tumor DNA and RNA. This technology has the potential to lead to more targeted and personalized cancer treatments by identifying genetic connections between cancer and race or ethnicity.
A new Japanese study found a substantial rise in renal replacement therapy incidence due to nephrosclerosis, while rates for diabetic nephropathy decreased. The number of patients with nephrosclerosis as a primary kidney disease is increasing, suggesting age-specific incidence rate increases
A new study found the annual incidence of Parkinson’s disease in the U.S. to be nearly 90,000 cases per year, a 50% increase from previous estimates of 60,000 diagnoses annually. The increased incidence is attributed to an aging population and highlights the need for more research and better treatments.
A recent study found that COVID-19 vaccination rates vary widely across the US, with underserved communities facing significant barriers to access, including cost, insurance coverage, and transportation. The analysis showed that people in these areas were 34% less likely to be vaccinated against COVID-19.
Global rates of type 2 diabetes in adolescents and young adults have increased significantly between 1990 and 2019, with countries with lower socioeconomic development and women under 30 showing the largest increases. High body mass index is the main contributing factor to this trend.
A recent study found that consuming the most vegetables, including leafy greens and cruciferous veggies, was associated with a lower risk of developing Type 2 diabetes. Meanwhile, potatoes may not have the same benefits but aren't bad if prepared in a healthy way.
Research suggests that long-lasting insecticidal malaria nets lost their effectiveness after just one year in Burundi, contradicting the recommended replacement every 3 years. The study found that malaria incidence rose again after two years, highlighting the need for continued epidemiological monitoring and improved resource allocation.
A global Phase 2/3 clinical trial found that vaccination with SCB-2019 reduced the risk of transmitting SARS-CoV-2 infection to household members. The study showed a significant reduction in symptomatic cases among vaccinated household contacts and indicated that vaccines can play an important role in controlling future outbreaks.
Research found that male rats exposed to ifosfamide during adolescence had offspring and grand-offspring with increased incidence of diseases, including kidney and testis problems. The study's epigenetic analysis revealed changes passed down through sperm and ova, indicating a potential risk for future generations.
A study led by Dr. Ashish Deshmukh finds a significant increase in anal cancer incidence among women and men over 50 years old in the Midwestern and Southeastern states, with HPV infections and smoking identified as key risk factors.
A research team at the University of California, Riverside has discovered the structure of a human monoclonal antibody that protects against Crimean Congo Hemorrhagic Fever virus. The study provides insights into fighting a broad range of viral strains and could lead to targeted therapeutics for infected patients.
Black and Hispanic men are underrepresented in prostate cancer clinical trials compared to their incidence rate. The representation of Black patients has remained consistently low over the past two decades.
The American College of Physicians recommends policies to improve healthcare access and quality for incarcerated patients, including adequate funding and timely access to necessary services. The organization also supports treating substance use disorders as an alternative to incarceration.
Researchers found a 3% per year increase in cervical cancer incidence in women in their early 30s, starting from 2012, and an increase in both localized and regional disease. The study suggests that improved screening rates are needed to address the rising incidence.
A large South Korean cohort study found a five-fold increased risk of chronic kidney disease (CKD) for adults with persistent hematuria. Associations were stronger in men compared to women.
A large study found that children who experienced adversity, including serious family illness or death, poverty, neglect, or dysfunctional relationships, are at increased risk of developing cardiovascular disease in early adulthood. The study, published in the European Heart Journal, followed nearly 1.3 million children and found a 60%...
Researchers found a significant increase in Kaposi's sarcoma incidence among young Black men in the South, with rates jumping by 3.3% per year. The study suggests that HIV infection and social determinants like poverty and lack of access to medical care contribute to this disparity.
A study published in the New England Journal of Medicine found that new onset CKD rates are higher among Native Hawaiian/Pacific Islander, Black, American Indian/Alaska Native, and Hispanic/Latino populations compared to white persons with diabetes. The rate declined from 8% in 2015-2016 to 6.4% in 2019-2020.
A large-scale analysis of VA medical centers found that facilities with lower yearly PSA screening rates had higher rates of metastatic prostate cancer in subsequent years. The study supports the benefits of prostate cancer screening in reducing metastatic prostate cancer risk, particularly for high-risk groups like Black patients.
A study found that 16.5% of American adults with diabetes ration their insulin, with younger adults and the uninsured being most affected. Insulin rationing is often linked to cost concerns, with many patients delaying purchases or taking less insulin than needed.
A study found that each 10% increase in natural space is linked to a 7% fall in early deaths among under 65s. Increased availability of natural space within local areas also reduced the disparity in years of life lost between deprived and non-deprived areas.
A study reveals a high incidence of chronic kidney disease among adults with diabetes, particularly affecting Native Hawaiian/Pacific Islander, Black, American Indian/Alaska Native, and Hispanic/Latino(a) groups. The rate of new onset CKD was higher in these groups by approximately 60%, 40%, 33%, and 25% compared to White persons with ...
The American College of Physicians recommends increasing funding for health services and prioritizing health promotion in Indigenous communities. Community-driven public policy is also necessary to address historical trauma, social determinants of health, and inadequate access to healthcare services.
A large JAMA study found hospitalizations for COVID-19 disease occurred mostly in high-risk patients, including older adults and those with comorbidities. Vaccination and booster shots significantly reduced the incidence of severe COVID-19 illness among all age groups.
Global liver cancer cases are estimated to rise by more than 55% by 2040 unless preventive measures are strengthened. Countries must achieve at least a 3% annual decrease in liver cancer incidence and mortality rates to avoid this increase, according to a new report.
A national US kidney disease registry found that 60% of participants were unaware of their kidney function level, hindering clinical trial recruitment. The National Kidney Foundation Patient Network aims to address this issue through real-world data collection and patient-centered research.
A cohort study found that endoscopists performing colonoscopies in FIT-based screening programs should aim for markedly higher ADRs compared to primary colonoscopy screening. The study suggests that high ADRs are associated with lower colorectal cancer incidence and mortality. Researchers recommend using ADR targets, including differen...
A Brazilian study analyzed risk factors for heart attacks and found that high blood sugar had the most significant impact on mortality. Reducing smoking prevented most deaths from cardiovascular disease, while lowering diabetes incidence could have saved up to 5,000 lives over a decade.
A study led by Singapore scientists found that Neisseria, a genus of bacteria once considered harmless, can cause infections in patients with bronchiectasis, asthma, and COPD. The research team identified a specific subgroup of Neisseria called N. subflava as the main culprit behind worsening disease outcomes.
The study found a significant decline in peritoneal dialysis-associated peritonitis rates over time, with consistent differences in risk by race and age. The decline suggests improvements in clinical practice and highlights the importance of uniform coding standards to identify additional risk factors.
A new study found that young Swiss military personnel with confirmed Covid-19 infections experienced symptoms like fatigue, reduced sense of smell, and psychological problems for up to 180 days. Long-term effects included increased BMI, high cholesterol, and lower physical stamina, suggesting a higher risk of metabolic disorders and ca...
The study found a significant increase in the use of single-encounter thoracoabdominopelvic CT examinations and minor injuries between 2011-18. In commercially insured patients, rates rose from 3.4 to 9.8 for single-encounter thoracoabdominopelvic CT per 1,000 trauma-related ED encounters.
A study analyzing 2.8 million SARS-CoV-2 genomes reveals six gene-level mutations that have reached saturation, suggesting future variants are combinations of existing high-frequency mutations. The team also identifies 185 mutations positively correlated with viral transmission rates.
A study of 1,300 patients found most thyroid cancers are discovered in asymptomatic individuals, supporting the hypothesis of ongoing subclinical disease detection. The findings contradict the notion of a rising incidence of thyroid cancer.
Researchers at UC San Diego and Scripps Research developed a wastewater sequencing tool to track regional infection dynamics. This approach proved effective in identifying emerging variants and predicting COVID-19 surges, enabling early detection of cases and informing public health interventions.
A Rutgers-led study reveals racial disparities in HPV-associated throat cancer outcomes among males in the US. Black and Hispanic men are dying from throat cancer at a higher rate than white men, with most new cases being diagnosed at late stages.
A comprehensive study found that prenatal exposure to endocrine-disrupting chemicals is associated with non-alcoholic fatty liver disease in children. The researchers measured 45 chemicals in pregnant women and found elevated levels of biomarkers indicating risk for liver disease in children who were more highly exposed.
A new technique for detecting typhoidal Salmonella infections has been developed, allowing for faster and more accurate tracking of infections, particularly in rural areas. The approach detects typhoid antibodies in dried blood spots, providing valuable information for vaccination planning and disease surveillance.
The SHIELD program employed rapid saliva testing, real-time data analysis, and fast reporting to mitigate the spread of COVID-19. The program's success led to a significant reduction in cases and deaths on campus, with Champaign County experiencing a third less COVID-19 cases than expected.
The primary causes of liver cancer are changing globally, with advances in hepatitis B vaccinations and antiviral therapies reducing HBV-associated liver cancer. However, alcohol consumption and obesity are rising, leading to increased liver cancer deaths. The incidence of NASH is projected to increase further due to rising obesity rates.
Researchers found that mosquitoes whose slumber is disrupted are less interested in feeding, with a 54% decrease in feeding behavior. This phenomenon, called sleep rebound, highlights the importance of sleep for even insects.
Patients with primary glomerular diseases have a significantly higher risk of cardiovascular events, including coronary artery disease and stroke. The study found that inclusion of kidney-specific risk factors improved the prediction of cardiovascular events.
Researchers simulated COVID-19 transmission on a university campus, finding that universal mask usage and high vaccination rates can curb new infections. The study suggests that at least 93% of students should be vaccinated during highly transmissible variant outbreaks.
Researchers are monitoring children for exposure to and responses to emerging pathogens, aiming to develop diagnostic, therapeutic and preventive tools for future pandemics. The study will inform the development of tests, treatments and vaccines that may be used in future pandemics.
Research suggests that EMFs can cause Alzheimer's disease by building up calcium levels in brain cells. This increase leads to changes in the brain, which develop conditions for Alzheimer's. The study highlights the importance of reducing EMF exposure to prevent or delay the onset of Alzheimer's.
The COVID-19 pandemic has led to a setback in global efforts to meet SDG targets for tackling tuberculosis. TB mortality plateaued in Europe between 2019 and 2020, likely due to disruptions in essential TB services. Researchers highlight the need for continued commitment and investments to prevent further progress being reversed.
Researchers at Clemson University have identified a genetic variation associated with congenital idiopathic megaesophagus (CIM) in German shepherd dogs, which is often fatal if left untreated. A genetic test using melanin-concentrating hormone receptor 2 and dog's sex can predict the risk of CIM with 75% accuracy.
A new study from Karolinska Institutet projects that a temperature rise of 2 degrees Celsius will increase hyponatremia hospitalizations by almost 14%. Women and elderly are particularly vulnerable to the increased risk, with those over 80 years old facing a 15 times higher chance of hospitalization during heat waves.