Articles tagged with Disease Incidence
Research finds military veterans exposed to low doses of chemical warfare agents have higher rates of mortality from genitourinary diseases and deaths attributable to alcohol. However, overall cancer incidence is not significantly associated with Porton Down attendance.
Scientists discovered that inhibiting microRNA-141-3p can reduce chronic inflammation, muscle loss, and bone degradation in aged mice. By blocking this tiny RNA, researchers found improvements in the spleen's immune response, lower levels of pro-inflammatory proteins, and a more youthful profile in bones and muscles.
A study found that young women are more likely to experience adverse outcomes and rehospitalization after a heart attack, with non-cardiac hospitalizations showing the most significant disparity. Researchers highlight the need for public awareness and sex-specific post-heart attack care.
A case series study found prostate cancer occurs in transgender women, contrary to previous reports suggesting rarity. Rates were lower than anticipated based on prior male veteran prostate cancer incidence estimates.
A systematic review and meta-analysis found that SARS-CoV-2 infection significantly increases the risk of Bell palsy, whereas vaccination poses a lower risk. The Pfizer/BioNTech vaccine did not differ significantly from the Oxford/AstraZeneca vaccine in terms of BP incidence.
The study revealed lower age-standardized rate of NENs incidence in China (1.14 per 100,000) compared to the USA (6.26 per 100,000). The most common sites for primary NEN tumors progressed were found to be the pancreas, stomach, lungs, and rectum.
A new study found that unintentional weight loss is grossly under-recognized in primary care, with only 21% recognized by doctors. The researchers recommend using electronic health record alerts to prompt clinicians to ask about intentional or unintentional weight loss, which can be a sign of a serious underlying condition.
Researchers discuss rapamycin's potential to delay cancer onset by slowing cell proliferation and tumor progression. The mTOR pathway is involved in both cancer and aging, making rapamycin a promising chemopreventive agent.
A study by Tufts University researchers estimates that poor diet contributed to over 14.1 million cases of type 2 diabetes in 2018, accounting for 70% of new diagnoses globally. The analysis found that diets rich in refined grains and processed meat had the greatest impact on type 2 diabetes incidence.
The highest incidence of invasive Group A Streptococcus (GAS) disease has shifted from the most deprived groups to the second most affluent group in the UK, according to new research. The emm1 strain, which causes severe disease, was more common in 2022 than previous years.
Denmark has seen a significant surge in strep A infections, particularly among the elderly, since late 2022. The new M1 subvariant is responsible for 30% of cases and may be contributing to the outbreak's severity.
Infections caused by Group A Streptococcus (GAS) decreased by 80% as COVID-19 lockdown took effect and remained low until March 2022, when they increased 18% a month to surpass pre-COVID levels.
A Japanese study reveals significant birth cohort effects on ESKD requiring RRT, with increased risk for men born in the 1940-60s and women born in 1930–40s. Poor environmental conditions during World War II may contribute to this trend.
A study of over 43,000 adults found that parathyroidectomy has no estimated effect on long-term kidney function in older adults. However, early treatment may preserve kidney function in patients younger than 60 years old.
Researchers propose a new method of clustering colorectal cancer patients using differential presence of exons (DPE) sequencing, which can provide valuable information on CRC progression and response to therapy. This analysis may also reduce costs and time required for staging CRC patients.
A recent study by the University of Jyväskylä found that good physical fitness in children does not reduce low-grade inflammation, which is a key factor in childhood obesity. Higher body fat percentage and waist circumference were strongly associated with higher low-grade inflammation levels.
The LSU Health New Orleans Louisiana Tumor Registry released the sixth report of statewide cancer incidence rates by census tract, finding that 81% of tracts met criteria for all cancers combined. Census tracts with statistically higher incidence rates were found in parishes including Orleans, Lafourche, and St. Bernard.
A new study from Mass General Brigham researchers found that early menopause may be a risk factor for Alzheimer's disease dementia. However, women who received hormone therapy around the time of menopause onset did not experience an increased risk of dementia. The study suggests that timing is crucial when it comes to hormone therapy, ...
Global efforts to track HIV and HCV incidence among people who inject drugs are necessary to validate targets for ending the epidemics by 2030. The research highlights the importance of prioritizing this population in prevention and elimination work, particularly for vulnerable subgroups like young people and women.
The study found a 1.14% incidence rate of moderate and severe OHSS among Chinese women of reproductive age between 2013 and 2017. Women under 35 years old receiving ART are at high risk, accounting for 80% of new cases during this period.
The European Union and European Economic Area will likely fall short of the Sustainable Development Goals target for eliminating tuberculosis by 2030. To meet the goal, an annual decline of 11.7% is needed in TB incidence, whereas the current decline rate of 6.8% is insufficient.
A recent study found that malaria control programs in Amazonian Peru reduced the disease by 78% but saw a rebound when funding was cut, driven by climate change. Climate change has exacerbated malaria transmission, with rising temperatures and intense rainfalls contributing to the resurgence of the mosquito-borne disease.
A study published in Lancet Diabetes & Endocrinology found that the incidence of type 1 diabetes among Finnish children increased by 16% during the pandemic. Researchers believe that social isolation and lockdowns rather than SARS-CoV-2 infection may have contributed to this increase.
A population data linkage study found fewer people in Wales diagnosed with long-term conditions in 2020 and 2021 than expected, indicating a potential backlog of undiagnosed patients. This disparity affects chronic obstructive pulmonary disease (COPD) and anxiety disorders, corresponding to over 30 and 80 missing diagnoses respectively.
A global study aims to better understand the burden of Human papillomavirus (HPV) among girls and women in low- and lower middle-income countries. The study will inform effective strategies to prevent infection and introduce HPV vaccine into national programs, protecting the health of girls and women and reducing rates of cervical cancer.
A new study found that women with BRCA1 or BRCA2 mutations have a cumulative risk of 49% developing any type of cancer after age 50. Risk-reducing surgeries like mastectomies and BSOs can lower this risk, but many women opt out despite elevated risk. Genetic testing is crucial for accurate risk assessment and personalized care.
A new study found that individuals with a normal gastrointestinal biopsy still have a higher risk of developing inflammatory bowel disease (IBD) in the years following the biopsy. The study of over 450,000 individuals in Sweden showed that symptoms of IBD may start significantly before the disease shows up on biopsy.
A new Stanford-led study uses satellite and land use data to predict malaria outbreaks in Madagascar, providing insights into the disease's distribution and burden. The research identifies rural areas with flooded rice fields as high-risk zones for malaria transmission.
Researchers analyzed data on European travellers arriving from Africa between 2015 and 2019, finding malaria as the most common arthropod-borne disease. The study highlights the importance of using travellers' health data to complement local surveillance systems in Africa.
A Chinese Medical Journal study analyzed the temporal and spatial distribution of epilepsy across China, finding significant increases in incidence and prevalence rates between 1990 and 2019. The study also showed a general decrease in age-standardized DALY rates with increasing socio-demographic index.
A recent study monitored the Italian province of Pescara for 18 months and found no increased risk of serious diseases among vaccinated individuals. The study revealed that vaccinated persons were more protected against COVID-19 and had lower rates of deaths and disease occurrences compared to non-vaccinated individuals.
A Rutgers study found that older people living with HIV/AIDS face unmet mental health needs and are more likely to experience PTSD, substance dependence, and suicidal thoughts. Resilience may play a crucial role in increasing adherence to antiretroviral therapy, which is essential to ending the AIDS epidemic.
A study of 57,460 US cases found a sustained decrease in infant pertussis incidence following Tdap vaccine introduction. Maternal vaccination is associated with reduced disease burden among young infants.
A new study found that women with pre-pregnancy migraine had greater risks of preterm delivery, gestational hypertension, and preeclampsia. Migraine with aura was associated with a higher risk of preeclampsia than without aura.
Researchers analyzed data from the VITAL trial and found that vitamin D supplementation increased biomarkers associated with vitamin D metabolism in people, regardless of their weight. However, these increases were significantly smaller in people with elevated BMIs, suggesting a blunted response to supplementation.
A large cohort study found that long-term low-dose hydroxychloroquine use is associated with a low risk of developing retinopathy, while higher doses increase the risk. Regular screening can identify the issue at an early stage.
Researchers from prominent institutions discuss hepatocellular carcinoma's pathogenesis, genomic heterogeneity, and targeted therapy options. The review aims to characterize HCC's complexities and develop clinically relevant biomarkers for better management.
A new software developed by researchers at Cold Spring Harbor Laboratory can accurately infers continental ancestry from tumor DNA and RNA. This technology has the potential to lead to more targeted and personalized cancer treatments by identifying genetic connections between cancer and race or ethnicity.
A new Japanese study found a substantial rise in renal replacement therapy incidence due to nephrosclerosis, while rates for diabetic nephropathy decreased. The number of patients with nephrosclerosis as a primary kidney disease is increasing, suggesting age-specific incidence rate increases
A recent study found that COVID-19 vaccination rates vary widely across the US, with underserved communities facing significant barriers to access, including cost, insurance coverage, and transportation. The analysis showed that people in these areas were 34% less likely to be vaccinated against COVID-19.
A new study found the annual incidence of Parkinson’s disease in the U.S. to be nearly 90,000 cases per year, a 50% increase from previous estimates of 60,000 diagnoses annually. The increased incidence is attributed to an aging population and highlights the need for more research and better treatments.
Global rates of type 2 diabetes in adolescents and young adults have increased significantly between 1990 and 2019, with countries with lower socioeconomic development and women under 30 showing the largest increases. High body mass index is the main contributing factor to this trend.
A recent study found that consuming the most vegetables, including leafy greens and cruciferous veggies, was associated with a lower risk of developing Type 2 diabetes. Meanwhile, potatoes may not have the same benefits but aren't bad if prepared in a healthy way.
Research suggests that long-lasting insecticidal malaria nets lost their effectiveness after just one year in Burundi, contradicting the recommended replacement every 3 years. The study found that malaria incidence rose again after two years, highlighting the need for continued epidemiological monitoring and improved resource allocation.
A global Phase 2/3 clinical trial found that vaccination with SCB-2019 reduced the risk of transmitting SARS-CoV-2 infection to household members. The study showed a significant reduction in symptomatic cases among vaccinated household contacts and indicated that vaccines can play an important role in controlling future outbreaks.
A study led by Dr. Ashish Deshmukh finds a significant increase in anal cancer incidence among women and men over 50 years old in the Midwestern and Southeastern states, with HPV infections and smoking identified as key risk factors.
A research team at the University of California, Riverside has discovered the structure of a human monoclonal antibody that protects against Crimean Congo Hemorrhagic Fever virus. The study provides insights into fighting a broad range of viral strains and could lead to targeted therapeutics for infected patients.
Research found that male rats exposed to ifosfamide during adolescence had offspring and grand-offspring with increased incidence of diseases, including kidney and testis problems. The study's epigenetic analysis revealed changes passed down through sperm and ova, indicating a potential risk for future generations.
Black and Hispanic men are underrepresented in prostate cancer clinical trials compared to their incidence rate. The representation of Black patients has remained consistently low over the past two decades.
The American College of Physicians recommends policies to improve healthcare access and quality for incarcerated patients, including adequate funding and timely access to necessary services. The organization also supports treating substance use disorders as an alternative to incarceration.
Researchers found a 3% per year increase in cervical cancer incidence in women in their early 30s, starting from 2012, and an increase in both localized and regional disease. The study suggests that improved screening rates are needed to address the rising incidence.
A large South Korean cohort study found a five-fold increased risk of chronic kidney disease (CKD) for adults with persistent hematuria. Associations were stronger in men compared to women.
A large study found that children who experienced adversity, including serious family illness or death, poverty, neglect, or dysfunctional relationships, are at increased risk of developing cardiovascular disease in early adulthood. The study, published in the European Heart Journal, followed nearly 1.3 million children and found a 60%...
Researchers found a significant increase in Kaposi's sarcoma incidence among young Black men in the South, with rates jumping by 3.3% per year. The study suggests that HIV infection and social determinants like poverty and lack of access to medical care contribute to this disparity.
A study published in the New England Journal of Medicine found that new onset CKD rates are higher among Native Hawaiian/Pacific Islander, Black, American Indian/Alaska Native, and Hispanic/Latino populations compared to white persons with diabetes. The rate declined from 8% in 2015-2016 to 6.4% in 2019-2020.
A large-scale analysis of VA medical centers found that facilities with lower yearly PSA screening rates had higher rates of metastatic prostate cancer in subsequent years. The study supports the benefits of prostate cancer screening in reducing metastatic prostate cancer risk, particularly for high-risk groups like Black patients.
A study found that 16.5% of American adults with diabetes ration their insulin, with younger adults and the uninsured being most affected. Insulin rationing is often linked to cost concerns, with many patients delaying purchases or taking less insulin than needed.
A study found that each 10% increase in natural space is linked to a 7% fall in early deaths among under 65s. Increased availability of natural space within local areas also reduced the disparity in years of life lost between deprived and non-deprived areas.
A study reveals a high incidence of chronic kidney disease among adults with diabetes, particularly affecting Native Hawaiian/Pacific Islander, Black, American Indian/Alaska Native, and Hispanic/Latino(a) groups. The rate of new onset CKD was higher in these groups by approximately 60%, 40%, 33%, and 25% compared to White persons with ...
The American College of Physicians recommends increasing funding for health services and prioritizing health promotion in Indigenous communities. Community-driven public policy is also necessary to address historical trauma, social determinants of health, and inadequate access to healthcare services.