Articles tagged with Allergies
A recent NIH study found associations between exposure to ozone and fine particulate matter and molecular changes in children's airways during non-viral asthma attacks. The study suggests that reducing air pollution could improve human health, particularly in urban communities with high-risk asthma populations.
A new study from the University of Virginia Health System found that mRNA booster shots increase the durability of antibodies to COVID-19. The boosters led to longer-lasting antibodies, even in those who had previously recovered from a COVID-19 infection.
Two new yardsticks have been published by the American College of Allergy, Asthma and Immunology to guide practitioners on treating eosinophilic esophagitis and managing cough in adults and adolescents. The yardsticks provide practical, evidence-based recommendations for clinical decision-making.
Researchers at La Jolla Institute for Immunology have found that the inflammatory molecule LIGHT leads to airway remodeling and long-term breathing issues in severe asthma. Therapeutics targeting LIGHT could reverse airway and lung damage, offering a potential long-term treatment for asthma.
Research by Uppsala University and Swedish University of Agricultural Sciences links atopic dermatitis in dogs to specific genome regions. The study identifies genes coinciding with human atopic eczema, including the filaggrin gene region.
Researchers at Rutgers University simulated climate change's impact on allergenic pollens, finding significant increases in airborne pollen loads by 2050. The study predicts earlier start times and longer durations for pollen seasons across the US, with notable regional shifts.
A new study by researchers at the Swiss Institute of Allergy and Asthma Research found that commercial dishwashers' rinse agents can damage the gut's epithelial barrier, leading to chronic diseases. The study used human intestinal organoids and analyzed the effect of detergents and rinse aids on gut cells.
A new study found that small molecules in breast milk, specifically miR-375, can reduce the likelihood of infants developing allergic conditions like atopic dermatitis and food allergies. Infants who consumed more miR-375 had lower rates of these conditions, suggesting a potential protective effect of breast milk against allergies.
A study by the American College of Allergy, Asthma, and Immunology found that pollen levels are lowest during early morning hours, with lower counts occurring between 4:00 a.m. and noon. This information can help individuals with pollen allergies plan their outdoor activities accordingly.
Eczema affects 10-20% of Canadian infants, making it a common condition to manage. Optimally managing atopic dermatitis in infants is crucial, as it impacts the whole family.
A study published in Nature identifies the central functions of group 2 innate lymphoid cells (ILC2s), which play a crucial role in combating parasitic diseases and promoting mucus production. The researchers found that ILC2s are essential for immune response and cannot be replaced without compromising its effectiveness.
Most healthy infants can digest lactose as is, but excessive use of hypoallergenic and lactose-reduced formulas is noted. Analysis found 5.5% of formula purchased was hypoallergenic and 59% lactose-reduced, with lactose being only 47% of the carbohydrate source in formulas.
A new study published in Annals of Allergy, Asthma and Immunology found that targeted cognitive behavioral therapy (CBT) significantly lessens food allergy-related anxiety for both children and parents. The treatment included proximity exposure sessions with the patient, resulting in improved symptoms and quality of life.
A new guideline published in Clinical & Experimental Allergy aims to improve the testing process for penicillin allergies among patients. The guidelines provide recommendations on patient selection, risk stratification, and drug provocation testing, aiming to reduce errors and ensure accurate diagnosis.
A new biologic drug has been found to be highly effective in reducing the signs and symptoms of moderate-to-severe eczema in infants and young children. The study showed that more than half of treated children experienced a 75% reduction in eczema symptoms, leading to improved sleep and increased ability to lead normal lives.
A new study published in Annals of Allergy, Asthma and Immunology found that 36% of YouTube videos on hay fever contained misleading information, leading to increased user interaction. Medical associations were the most reliable source of information, with only 32% of TV show/YouTube channel videos classified as useful.
Pollen from ragweed plants in different regions exhibits varying levels of aggression, influencing allergic reactions. Climate change is projected to increase ragweed allergy cases to 77 million by 2060.
A Houston Methodist study found that a minimally invasive procedure using temperature-controlled radiofrequency intervention is safe and effective in improving symptoms of chronic rhinitis. After 12 months, patients reported a 57.8% improvement in symptoms, with minor side effects observed in a few individuals.
A new study published in Clinical & Experimental Allergy reveals a 4-fold increase in allergy clinics for children in the UK, but most are small and vary in services offered. The research highlights the need for standardized care through national networks and simulation training to ensure safe service provision.
Children born to mothers with polycystic ovary syndrome (PCOS) are at a higher risk of developing infections, allergies, and other childhood illnesses by age 13. The study found that children of mothers with PCOS were 32% more likely to be admitted to hospital for various health problems.
A new study found that while the availability of lower-priced epinephrine auto-injector competitors has improved affordability for many patients, a significant minority still pay significantly more for life-saving medication. High-deductible health plans are a major contributing factor to these high costs.
Research published in Clinical and Experimental Allergy reveals a significant increase in prescriptions of specialized infant formula for infants with milk allergies. The findings suggest high levels of milk allergy over-diagnosis, marking an important shift in early child nutrition.
A research team at MedUni Vienna has discovered key mechanisms of mugwort allergy, laying the foundation for a potential vaccine. The study found that fragments of the major mugwort pollen allergen can be used for effective therapy, providing a promising first step towards causal therapy and prevention.
A new study published in the Journal of Allergy and Clinical Immunology: In Practice found that infants under 12 months who undergo oral immunotherapy have a better safety profile compared to older preschoolers. The treatment, which involves gradually increasing exposure to peanut flour, is highly effective and safe for this age group.
A new study published in PNAS Nexus shows how artificial light at night alters the natural seasonal processes of plants in urban regions of the United States. The study found that levels of artificial light during nighttime hours lengthen pollen season for many plants, affecting city dwellers with allergies.
A study by NIH found that people with food allergies have a lower risk of becoming infected with SARS-CoV-2. In contrast, obesity and high body mass index (BMI) are associated with increased risk for SARS-CoV-2 infection.
Engineers at Stanford University have developed a microfluidic system that isolates allergen-reactive basophils from blood samples using magnetic nanoparticles. The device achieves purities and recovery over 95% in just 10 minutes, making it accessible to clinics and diagnostic labs.
A global study found a combination of two drugs dramatically reduces the chances of suffering an asthma attack. The combination of albuterol and budesonide lowers the number of sudden episodes of shortness of breath, wheezing, and coughing in patients.
The efficacy of Palforzia in treating peanut allergies is being called into question by Dr. Michael R. Perkin, who raises concerns about adverse events and potential long-term side effects. The editorial review aims to provide a balanced perspective on the treatment option.
Adults with a history of allergic disorders are at increased risk of developing high blood pressure and coronary heart disease. Asthma is the primary contributor to this risk, particularly among Black male adults.
Researchers at Tokyo University of Agriculture and Technology discovered that double-stranded RNA molecules can activate the immune system response leading to bone deterioration in gum disease. The study found that dsRNA triggers the differentiation of osteoclasts, cells responsible for breaking down bone, leading to increased bone ero...
Researchers found that seven patients with inflammatory skin conditions experienced anaphylaxis after using goat's milk or cheese products. The study highlights the potential risks of using foodstuffs as therapy for inflammatory skin conditions, leading to new allergies.
Researchers have identified formononetin as a potential therapeutic for treating food allergies, which affect nearly 10% of the world population. The plant compound has been shown to decrease IgE production and influence gene and protein targets regulated in food allergy and mast cell diseases.
Researchers at InBio have made progress in developing a hypoallergenic cat by targeting the Fel d 1 protein using CRISPR-Cas9. The study suggests that Fel d 1 is nonessential for cats, paving the way for further experiments exploring genetic therapy to reduce cat allergens.
This year's Experimental Biology 2022 meeting features groundbreaking studies on COVID-19 vaccine-associated symptoms in non-menstruating people, a plant compound showing promise for alleviating food allergies, and the potential of omega-3s to boost immunotherapy's cancer-fighting power. Researchers also explore the safety of using CBD...
The Experimental Biology (EB) 2022 meeting features live presentations and a moderated Q&A session on groundbreaking studies. The virtual press conference reveals potential treatments for Parkinson's disease, COVID-19 vaccine-associated side effects, and alleviating food allergies.
Researchers have identified a unique population of memory CD4 T-cells that produce IL-9, which plays a key role in allergic memory responses. Blocking this cytokine may lead to reduced lung inflammation and improved treatment options for seasonal asthma.
Despite scientific consensus against their role, formula milk companies continue to market allergy-reducing products in countries like China and Russia. Hydrolysed formulas are claimed to ease digestion and prevent allergies, but most claims have been debunked by researchers.
Researchers found an association between a specific HLA-DPB1 gene variant and poor response to sublingual immunotherapy (SLIT) for Japanese cedar pollinosis. The study suggests that genotyping the HLA-DPB1 gene could help predict patient responsiveness to SLIT.
Researchers developed a microneedle treatment that increased desensitization rates to peanut allergy in mice, outperforming existing immunotherapy methods. The novel approach achieved significant results using lower doses of allergen, offering new hope for millions suffering from peanut allergy.
A new patient-centered intervention reduced severe asthma exacerbations by 15% in African American/Black and Hispanic/Latinx patients with moderate-to-severe asthma. The study also found improved asthma symptoms and days of impairment, mirroring previous recommendations for patients with similar conditions.
The study defines the lung macrophage as a major target of IL-9, which promotes allergic lung inflammation. The researchers found a correlation between IL-9 and the diagnosis of asthma in patients, suggesting a potential therapeutic approach for treatment.
A study published in Allergy reveals the importance of PU.1 transcription factor in regulating CCL17 gene expression, which contributes to allergic diseases. The research found that suppressing PU.1 can reduce inflammation in asthmatic mice, paving the way for novel treatments.
A recent study identified several protein biomarkers that protect against the development of inflammatory diseases such as psoriasis and osteoarthritis. The researchers used Mendelian Randomization to determine whether high levels of these proteins are associated with a lower risk of disease.
A University of Bristol-led study found that three-quarters of infants experience two or more symptoms associated with cow's milk allergy, yet the condition only affects one in 100. These symptoms are often common and normal in healthy infants, suggesting guidelines may unintentionally medicalize normal infant symptoms.
A study by Tokyo University of Science researchers identifies a novel regulatory axis targeting dendritic cell activity, suppressing autoimmune disease symptoms and bone loss. They discovered DCIR binds to glycoproteins on macrophages and osteoclasts, reducing inflammation and immune responses.
Researchers studied 4022 dogs fed different diets as puppies to see if it affected allergy and atopy related skin symptoms in adulthood. They found that puppies fed raw tripe, organ meats, and human meal leftovers had fewer allergies and skin issues.
Researchers at Tokyo Medical and Dental University discovered a genetic variant associated with a poorer prognosis of chronic hypersensitivity pneumonitis. The variant, rs5743899, was linked to increased immune activation and fibrosis, leading to reduced lung function in patients.
A new study finds that children who didn't have eggs introduced by 12 months were more likely to develop an egg allergy at 6 years. The research suggests early and frequent egg consumption during infancy may be protective against the development of egg allergy.
A new study found that most pregnant women with a penicillin allergy label are not allergic, but rather have Group B Strep or need antibiotics for labor. Testing for penicillin allergy can help reduce antibiotic exposure and ensure safer treatment options.
A new study reveals that many young adults with asthma are not prepared to transition to adult asthma care. The survey found that half of all respondents did not receive sufficient transition preparation from their pediatric providers, highlighting the need for better education and support.
A new study followed 5,000 kids with asthma in Los Angeles for 15 years and found no significant increase in allergic sensitizations to environmental allergens. Despite rising temperatures and pollen loads, children with asthma were not more likely to become sensitized to specific pollens.
A new study published in Nutrients found that consuming fermented soy product ImmuBalance reduces eosinophilic-related inflammation in the bronchi of asthma model mice. The researchers also discovered a suppression of proteins that induce eosinophilic inflammation, suggesting beneficial effects for allergic asthma.
Breast milk from Mennonite moms on farms contains higher concentrations of IgA antibodies against food allergens and bacteria associated with farm animals. Babies born to these mothers show reduced rates of atopic diseases, suggesting a protective factor passed on through breast milk.
Researchers found a correlation between allergic diseases and mental health conditions, including depression and anxiety, but cautioned that the link may not be causal. Future studies aim to explore potential treatments for both conditions.
Researchers investigated whether allergic diseases cause mental health conditions, finding little evidence of a causal relationship. The study used Mendelian Randomisation to identify genetic variants linked to allergies and mental health, but found no associations between the two.
A new study found that 31% of children with food allergies experience victimization behaviors, including verbal teasing and criticism, compared to 17% when asked a simple yes/no question. Only 12% of parents reported being aware of the issue.
Researchers at the University at Buffalo have developed a new treatment that pairs essential proteins with lysophosphatidylserine to build immune tolerance and prevent antibody development, potentially treating autoimmune disorders and allergies.
A Wayne State University researcher has been awarded a $1.93 million NIH grant to investigate the impact of maternal immunoglobulin D on infant immune protection against food allergies. The study aims to elucidate the mechanisms of placental IgD transfer and its potential as a prophylactic fetal immune education cue.
A new study has found that the composition of a baby's first poop is associated with whether or not they will develop allergies within their first year of life. Newborns with richer meconium have a lower risk of developing allergies, suggesting that early exposure to certain molecules in the womb may play a role in future health.