Articles tagged with Allergies
Researchers identify immune cells responsible for some hard-to-treat asthma cases, particularly in men who develop asthma later in life. These cells can cause severe inflammatory responses and do not respond to treatment.
Researchers identify cytotoxic CD4+ tissue-resident memory T cells as potential asthma triggers, particularly in older male patients. These cells can cause severe inflammatory responses and make treatment challenging.
Researchers from Karolinska Institutet challenge the hygiene hypothesis by showing that mice with high infectious exposures have a similar ability to develop allergic immune responses as laboratory mice. Despite this, they developed strong signs of pathological inflammation and allergic responses when exposed to allergens.
Researchers found a common bacterial signature associated with the development of eczema, asthma, food allergy, and hay fever in children. The study suggests that early life influences on gut microbiota may play a key role in the development of these allergies.
Researchers found that all 22 babies achieved a reduced sensitivity to peanuts after completing the treatment. After an oral food challenge, 91% of them could tolerate peanuts without triggering any allergic reactions.
Eosinophilic esophagitis (EoE) is triggered by food allergies or airborne allergens, causing inflammation and damage to the esophagus. A new study found that inhibiting the NLRP3 pathway and releasing Interleukin-18 prevents EoE development.
The study used electronic health record data from over 200,000 children to describe patterns of pediatric allergies across the US, validating the 'allergic march' pattern. It also found that eosinophilic esophagitis (EoE) is more common among non-White patients than previously reported.
A review highlights the importance of supporting breastfeeding in India, where one-quarter of the world's children are born. The authors express concern that excessive concern about infant allergies may be undermining mother-infant bonding, breastfeeding, and child nutrition.
The study found that food allergies were highest among Asian, Hispanic, and non-Hispanic Black individuals compared to non-Hispanic white individuals. Socioeconomic factors and environmental exposures may contribute to the disparity in food allergy prevalence.
A UC Riverside-led study reveals the Salton Sea environment is toxic, causing sulfuric smells, dust storms, chemicals, and fires that contribute to chronic health conditions like asthma and respiratory illnesses. The study's findings have important public health implications for vulnerable child populations.
Researchers found variability in IgA levels between blood and gut samples, suggesting IgA regulates commensal microbes to prevent immune dysregulation. Patients with normal fecal IgA were less likely to develop symptoms, while those deficient in both blood and fecal IgA showed elevated inflammatory cytokines.
Researchers have developed chicken eggs without the protein that causes egg white allergies, confirming their safety profile. The modified eggs, called OVM-knockout, were tested and found to be free from ovomucoid proteins, making them a potential solution for individuals with egg allergies.
A recent study published in the Journal of Allergy and Clinical Immunology: In Practice found that women exposed to domestic abuse have a significantly higher risk of developing asthma and other atopic diseases. The research, led by the University of Birmingham, analyzed patient records and found a 52% increased risk of atopic disease ...
A new Finnish study found that a green living environment in early childhood does not prevent eczema, despite previous expectations. The study associated coniferous forests and agricultural areas with an elevated risk of eczema, particularly for children born in the spring.
Researchers at the University of Gothenburg have developed a new epoxy resin monomer based on isosorbide, a substance produced from glucose, to reduce contact allergies. The new monomer is far less allergenic and not based on Bisphenol A (BPA), a known endocrine disruptor.
A survey of allergists and immunologists reveals that diagnosing and treating hereditary angioedema can be challenging, particularly for patients in rural areas. Patients living in rural areas are more likely to face barriers to care, including longer travel times to reach medical facilities.
A study of over 65,000 Japanese infants found that those exposed to indoor pets during fetal development or early infancy had fewer food allergies. Children exposed to indoor dogs and cats were significantly less likely to experience specific allergies, while hamster exposure unexpectedly increased the incidence of nut allergies.
Alpha-gal syndrome is an allergy caused by lone star tick bites, leading to symptoms like stomach pain, diarrhea, and nausea. Patients with suspected alpha-gal should undergo a blood test to check for immunoglobulin E antibodies, and the main treatment is avoiding foods containing alpha-gal.
Researchers from Japan create a new model for estimating transepidermal water loss, providing a more realistic picture of skin water loss. The new method uses confocal laser microscopy and Raman spectroscopy to measure stratum corneum thickness and water content.
A comprehensive European allergy atlas has been compiled, revealing regional and climate-related differences in sensitisation to allergens. The study found varying sensitisation patterns across Europe, with certain regions having lower sensitivity to house dust mites and higher sensitivity to peanut and fruit allergens.
A new cutaquig study found that increasing infusion volume per site resulted in a reduction of injection sites, while increasing infusion rates decreased infusion duration. The research also showed that dosing every other week demonstrated equivalency to trough levels with weekly dosing.
A new review reveals that environments beyond greenspaces and bluespaces, such as caves, deserts, and glaciers, have potential health benefits. Short-term exposure to solid-state water landscapes showed little evidence of benefits, while longer-term exposure led to improved emotional states, medical treatments for allergies, and physic...
A new study found that eliminating animal milk alone from the diet of adults with eosinophilic esophagitis is just as effective as eliminating six common foods, including animal milk, eggs, wheat, soy, fish, and nuts. The one-food elimination diet may be a more manageable option for people with EoE.
Racial disparities in atopic dermatitis and food allergy affect people of color, with challenges including comfort level with healthcare providers and access to safe foods. Experts recommend 10 solutions to address these disparities, such as increasing diversity in clinical trials and providing culturally appropriate materials.
A phase 2 clinical trial using boiled peanuts followed by roasted peanuts showed promising results in desensitizing 80% of children with peanut allergies. Treatment-related adverse events were reported in 61% participants.
A recent NIH study found associations between exposure to ozone and fine particulate matter and molecular changes in children's airways during non-viral asthma attacks. The study suggests that reducing air pollution could improve human health, particularly in urban communities with high-risk asthma populations.
A new study from the University of Virginia Health System found that mRNA booster shots increase the durability of antibodies to COVID-19. The boosters led to longer-lasting antibodies, even in those who had previously recovered from a COVID-19 infection.
Two new yardsticks have been published by the American College of Allergy, Asthma and Immunology to guide practitioners on treating eosinophilic esophagitis and managing cough in adults and adolescents. The yardsticks provide practical, evidence-based recommendations for clinical decision-making.
Researchers at La Jolla Institute for Immunology have found that the inflammatory molecule LIGHT leads to airway remodeling and long-term breathing issues in severe asthma. Therapeutics targeting LIGHT could reverse airway and lung damage, offering a potential long-term treatment for asthma.
Research by Uppsala University and Swedish University of Agricultural Sciences links atopic dermatitis in dogs to specific genome regions. The study identifies genes coinciding with human atopic eczema, including the filaggrin gene region.
Researchers at Rutgers University simulated climate change's impact on allergenic pollens, finding significant increases in airborne pollen loads by 2050. The study predicts earlier start times and longer durations for pollen seasons across the US, with notable regional shifts.
A new study by researchers at the Swiss Institute of Allergy and Asthma Research found that commercial dishwashers' rinse agents can damage the gut's epithelial barrier, leading to chronic diseases. The study used human intestinal organoids and analyzed the effect of detergents and rinse aids on gut cells.
A new study found that small molecules in breast milk, specifically miR-375, can reduce the likelihood of infants developing allergic conditions like atopic dermatitis and food allergies. Infants who consumed more miR-375 had lower rates of these conditions, suggesting a potential protective effect of breast milk against allergies.
A study by the American College of Allergy, Asthma, and Immunology found that pollen levels are lowest during early morning hours, with lower counts occurring between 4:00 a.m. and noon. This information can help individuals with pollen allergies plan their outdoor activities accordingly.
Eczema affects 10-20% of Canadian infants, making it a common condition to manage. Optimally managing atopic dermatitis in infants is crucial, as it impacts the whole family.
A study published in Nature identifies the central functions of group 2 innate lymphoid cells (ILC2s), which play a crucial role in combating parasitic diseases and promoting mucus production. The researchers found that ILC2s are essential for immune response and cannot be replaced without compromising its effectiveness.
Most healthy infants can digest lactose as is, but excessive use of hypoallergenic and lactose-reduced formulas is noted. Analysis found 5.5% of formula purchased was hypoallergenic and 59% lactose-reduced, with lactose being only 47% of the carbohydrate source in formulas.
A new study published in Annals of Allergy, Asthma and Immunology found that targeted cognitive behavioral therapy (CBT) significantly lessens food allergy-related anxiety for both children and parents. The treatment included proximity exposure sessions with the patient, resulting in improved symptoms and quality of life.
A new guideline published in Clinical & Experimental Allergy aims to improve the testing process for penicillin allergies among patients. The guidelines provide recommendations on patient selection, risk stratification, and drug provocation testing, aiming to reduce errors and ensure accurate diagnosis.
A new biologic drug has been found to be highly effective in reducing the signs and symptoms of moderate-to-severe eczema in infants and young children. The study showed that more than half of treated children experienced a 75% reduction in eczema symptoms, leading to improved sleep and increased ability to lead normal lives.
A new study published in Annals of Allergy, Asthma and Immunology found that 36% of YouTube videos on hay fever contained misleading information, leading to increased user interaction. Medical associations were the most reliable source of information, with only 32% of TV show/YouTube channel videos classified as useful.
Pollen from ragweed plants in different regions exhibits varying levels of aggression, influencing allergic reactions. Climate change is projected to increase ragweed allergy cases to 77 million by 2060.
A Houston Methodist study found that a minimally invasive procedure using temperature-controlled radiofrequency intervention is safe and effective in improving symptoms of chronic rhinitis. After 12 months, patients reported a 57.8% improvement in symptoms, with minor side effects observed in a few individuals.
A new study published in Clinical & Experimental Allergy reveals a 4-fold increase in allergy clinics for children in the UK, but most are small and vary in services offered. The research highlights the need for standardized care through national networks and simulation training to ensure safe service provision.
Children born to mothers with polycystic ovary syndrome (PCOS) are at a higher risk of developing infections, allergies, and other childhood illnesses by age 13. The study found that children of mothers with PCOS were 32% more likely to be admitted to hospital for various health problems.
A new study found that while the availability of lower-priced epinephrine auto-injector competitors has improved affordability for many patients, a significant minority still pay significantly more for life-saving medication. High-deductible health plans are a major contributing factor to these high costs.
Research published in Clinical and Experimental Allergy reveals a significant increase in prescriptions of specialized infant formula for infants with milk allergies. The findings suggest high levels of milk allergy over-diagnosis, marking an important shift in early child nutrition.
A research team at MedUni Vienna has discovered key mechanisms of mugwort allergy, laying the foundation for a potential vaccine. The study found that fragments of the major mugwort pollen allergen can be used for effective therapy, providing a promising first step towards causal therapy and prevention.
A new study published in the Journal of Allergy and Clinical Immunology: In Practice found that infants under 12 months who undergo oral immunotherapy have a better safety profile compared to older preschoolers. The treatment, which involves gradually increasing exposure to peanut flour, is highly effective and safe for this age group.
A new study published in PNAS Nexus shows how artificial light at night alters the natural seasonal processes of plants in urban regions of the United States. The study found that levels of artificial light during nighttime hours lengthen pollen season for many plants, affecting city dwellers with allergies.
A study by NIH found that people with food allergies have a lower risk of becoming infected with SARS-CoV-2. In contrast, obesity and high body mass index (BMI) are associated with increased risk for SARS-CoV-2 infection.
Engineers at Stanford University have developed a microfluidic system that isolates allergen-reactive basophils from blood samples using magnetic nanoparticles. The device achieves purities and recovery over 95% in just 10 minutes, making it accessible to clinics and diagnostic labs.
A global study found a combination of two drugs dramatically reduces the chances of suffering an asthma attack. The combination of albuterol and budesonide lowers the number of sudden episodes of shortness of breath, wheezing, and coughing in patients.
The efficacy of Palforzia in treating peanut allergies is being called into question by Dr. Michael R. Perkin, who raises concerns about adverse events and potential long-term side effects. The editorial review aims to provide a balanced perspective on the treatment option.
Adults with a history of allergic disorders are at increased risk of developing high blood pressure and coronary heart disease. Asthma is the primary contributor to this risk, particularly among Black male adults.
Researchers at Tokyo University of Agriculture and Technology discovered that double-stranded RNA molecules can activate the immune system response leading to bone deterioration in gum disease. The study found that dsRNA triggers the differentiation of osteoclasts, cells responsible for breaking down bone, leading to increased bone ero...
Researchers found that seven patients with inflammatory skin conditions experienced anaphylaxis after using goat's milk or cheese products. The study highlights the potential risks of using foodstuffs as therapy for inflammatory skin conditions, leading to new allergies.
Researchers have identified formononetin as a potential therapeutic for treating food allergies, which affect nearly 10% of the world population. The plant compound has been shown to decrease IgE production and influence gene and protein targets regulated in food allergy and mast cell diseases.
Researchers at InBio have made progress in developing a hypoallergenic cat by targeting the Fel d 1 protein using CRISPR-Cas9. The study suggests that Fel d 1 is nonessential for cats, paving the way for further experiments exploring genetic therapy to reduce cat allergens.
This year's Experimental Biology 2022 meeting features groundbreaking studies on COVID-19 vaccine-associated symptoms in non-menstruating people, a plant compound showing promise for alleviating food allergies, and the potential of omega-3s to boost immunotherapy's cancer-fighting power. Researchers also explore the safety of using CBD...