Articles tagged with Allergies
This year's Experimental Biology 2022 meeting features groundbreaking studies on COVID-19 vaccine-associated symptoms in non-menstruating people, a plant compound showing promise for alleviating food allergies, and the potential of omega-3s to boost immunotherapy's cancer-fighting power. Researchers also explore the safety of using CBD...
Researchers have identified a unique population of memory CD4 T-cells that produce IL-9, which plays a key role in allergic memory responses. Blocking this cytokine may lead to reduced lung inflammation and improved treatment options for seasonal asthma.
Despite scientific consensus against their role, formula milk companies continue to market allergy-reducing products in countries like China and Russia. Hydrolysed formulas are claimed to ease digestion and prevent allergies, but most claims have been debunked by researchers.
Researchers found an association between a specific HLA-DPB1 gene variant and poor response to sublingual immunotherapy (SLIT) for Japanese cedar pollinosis. The study suggests that genotyping the HLA-DPB1 gene could help predict patient responsiveness to SLIT.
Researchers developed a microneedle treatment that increased desensitization rates to peanut allergy in mice, outperforming existing immunotherapy methods. The novel approach achieved significant results using lower doses of allergen, offering new hope for millions suffering from peanut allergy.
A new patient-centered intervention reduced severe asthma exacerbations by 15% in African American/Black and Hispanic/Latinx patients with moderate-to-severe asthma. The study also found improved asthma symptoms and days of impairment, mirroring previous recommendations for patients with similar conditions.
The study defines the lung macrophage as a major target of IL-9, which promotes allergic lung inflammation. The researchers found a correlation between IL-9 and the diagnosis of asthma in patients, suggesting a potential therapeutic approach for treatment.
A study published in Allergy reveals the importance of PU.1 transcription factor in regulating CCL17 gene expression, which contributes to allergic diseases. The research found that suppressing PU.1 can reduce inflammation in asthmatic mice, paving the way for novel treatments.
A recent study identified several protein biomarkers that protect against the development of inflammatory diseases such as psoriasis and osteoarthritis. The researchers used Mendelian Randomization to determine whether high levels of these proteins are associated with a lower risk of disease.
A University of Bristol-led study found that three-quarters of infants experience two or more symptoms associated with cow's milk allergy, yet the condition only affects one in 100. These symptoms are often common and normal in healthy infants, suggesting guidelines may unintentionally medicalize normal infant symptoms.
A study by Tokyo University of Science researchers identifies a novel regulatory axis targeting dendritic cell activity, suppressing autoimmune disease symptoms and bone loss. They discovered DCIR binds to glycoproteins on macrophages and osteoclasts, reducing inflammation and immune responses.
Researchers studied 4022 dogs fed different diets as puppies to see if it affected allergy and atopy related skin symptoms in adulthood. They found that puppies fed raw tripe, organ meats, and human meal leftovers had fewer allergies and skin issues.
Researchers at Tokyo Medical and Dental University discovered a genetic variant associated with a poorer prognosis of chronic hypersensitivity pneumonitis. The variant, rs5743899, was linked to increased immune activation and fibrosis, leading to reduced lung function in patients.
A new study followed 5,000 kids with asthma in Los Angeles for 15 years and found no significant increase in allergic sensitizations to environmental allergens. Despite rising temperatures and pollen loads, children with asthma were not more likely to become sensitized to specific pollens.
A new study finds that children who didn't have eggs introduced by 12 months were more likely to develop an egg allergy at 6 years. The research suggests early and frequent egg consumption during infancy may be protective against the development of egg allergy.
A new study found that most pregnant women with a penicillin allergy label are not allergic, but rather have Group B Strep or need antibiotics for labor. Testing for penicillin allergy can help reduce antibiotic exposure and ensure safer treatment options.
A new study reveals that many young adults with asthma are not prepared to transition to adult asthma care. The survey found that half of all respondents did not receive sufficient transition preparation from their pediatric providers, highlighting the need for better education and support.
A new study published in Nutrients found that consuming fermented soy product ImmuBalance reduces eosinophilic-related inflammation in the bronchi of asthma model mice. The researchers also discovered a suppression of proteins that induce eosinophilic inflammation, suggesting beneficial effects for allergic asthma.
Breast milk from Mennonite moms on farms contains higher concentrations of IgA antibodies against food allergens and bacteria associated with farm animals. Babies born to these mothers show reduced rates of atopic diseases, suggesting a protective factor passed on through breast milk.
Researchers found a correlation between allergic diseases and mental health conditions, including depression and anxiety, but cautioned that the link may not be causal. Future studies aim to explore potential treatments for both conditions.
Researchers investigated whether allergic diseases cause mental health conditions, finding little evidence of a causal relationship. The study used Mendelian Randomisation to identify genetic variants linked to allergies and mental health, but found no associations between the two.
A new study found that 31% of children with food allergies experience victimization behaviors, including verbal teasing and criticism, compared to 17% when asked a simple yes/no question. Only 12% of parents reported being aware of the issue.
Researchers at the University at Buffalo have developed a new treatment that pairs essential proteins with lysophosphatidylserine to build immune tolerance and prevent antibody development, potentially treating autoimmune disorders and allergies.
A Wayne State University researcher has been awarded a $1.93 million NIH grant to investigate the impact of maternal immunoglobulin D on infant immune protection against food allergies. The study aims to elucidate the mechanisms of placental IgD transfer and its potential as a prophylactic fetal immune education cue.
A new study has found that the composition of a baby's first poop is associated with whether or not they will develop allergies within their first year of life. Newborns with richer meconium have a lower risk of developing allergies, suggesting that early exposure to certain molecules in the womb may play a role in future health.
Researchers pinpointed cysteine leukotriene receptor 2 (CysLT2R) as a new target for treating chronic itch. The study found that activating this receptor induces itching in mouse models of atopic dermatitis, highlighting its potential role in contributing to the condition.
A meta-analysis found that the frequency of dual allergies to penicillin and cefazolin was only 0.7%, making it safe for nearly all patients with a penicillin allergy history. Cefazolin is now considered a suitable alternative to other antibiotics in surgery patients.
Researchers found a link between microorganisms in bed dust and children's bacteria, suggesting a potential reduction in asthma and allergy risks. The study analyzed bed dust samples from 577 infants and respiratory samples from 542 children, revealing a correlation between the two.
The new ATS clinical practice guideline provides comprehensive guidance on long-term and ambulatory oxygen therapy for adults with COPD and ILD. The guideline recommends LTOT for severe chronic resting room air hypoxemia in both COPD and ILD patients, and suggests ambulatory oxygen for moderate exertional room air hypoxemia in COPD pat...
A study of 14,572 children found that antibiotic use during the first two years of life is associated with an increased risk of asthma, respiratory allergies, eczema, obesity and attention deficit hyperactivity disorder. Antibiotic exposure was also linked to metabolic diseases, immunological diseases and cognitive conditions.
A new study reveals nearly one in five parents of children with food allergies are targeted by bullies, including parents and teachers. Parents found it helpful to intervene, with almost 50% reporting a positive outcome.
A new study found that hospitalized patients with COVID-19 and allergic conditions have similar rates of ICU admission and severity of disease. Researchers examined hospital data from 275 patients and found no significant differences in interventions needed for those with allergies versus those without.
A new study by the American College of Allergy, Asthma, and Immunology found that food allergies negatively affect the quality of life of those who suffer from them, particularly for Asian patients and their parents. The study showed higher negative quality of life scores for Asians compared to white and Black patients.
Black and Hispanic children in the US experience more severe eczema than their white counterparts. Additionally, they are less likely to report overall excellent health. The disparities exist due to differences in how the condition appears on diverse skin tones, requiring individualized treatment approaches.
A challenging case study found that wearing a face mask with elastic bands worsened a man's existing skin allergies. Common allergens in masks and their components can trigger symptoms in people with pre-existing skin conditions.
Researchers found caesarean section and prolonged labour influence infant gut microbiome, linked to childhood obesity and allergic sensitization. The study identified specific bacteria and metabolic pathways involved in these health outcomes.
Researchers discovered neuromedin B, a nervous system protein, prevents overactive immune responses and damaging inflammation in diseases like asthma, allergies, and COPD. The study provides hope for possible treatments using NMB to treat inflammatory diseases.
A recent survey of pediatricians found significant variability in recommendations for solid food introduction, leading experts to question the relevance of current guidelines. The long waiting period may delay peanut introduction and limit food diversity, which can decrease the development of allergic diseases in infants.
Two common gene variants in the KIF3A gene increase the risk of young children developing atopic dermatitis and food allergies. The study provides new insights into the genetic mechanisms underlying this condition, which affects up to 20% of all children.
Rising carbon dioxide levels and changes in the environment may contribute to increased prevalence of respiratory allergies, autoimmune diseases, and neurologic conditions such as autism. Disruptions to gut bacteria have also been linked to these disorders, highlighting the need for a greener lifestyle and reduced exposure to antimicro...
A new NIH study demonstrates that kidney transplantation between people with HIV can be done safely and effectively. The study found excellent graft survival rates, comparable to those of recipients receiving kidneys from HIV-negative donors, without significant differences in infection or adverse events rates.
Inaccurate antibiotic allergy records contribute to resistance, increased healthcare costs, and patient safety issues. The study suggests improving registration accuracy through training modules, guidelines, and better communication.
A new study found that mothers' traits, such as those present in the uterus during pregnancy, may increase the risk of allergies and asthma in children. By age 6, both parents presented the same risk, suggesting non-genetic factors play a role.
Dr. Richard Plemper, a Georgia State University researcher, has received a $3.65 million grant to develop antiviral therapeutics for respiratory syncytial virus (RSV) infections. The goal is to create cost-effective and well-tolerated treatments for RSV, which affects over three million hospitalizations annually.
A new study found that teenagers who go to bed late have a higher risk of developing asthma and allergic rhinitis symptoms. Researchers suspect that disruptions to melatonin production due to digital screen exposure may be the cause, and are urging clinicians to ask about sleep habits when diagnosing allergies and asthma.
Researchers identified IL-8 and IL-33 as key biomarkers for predicting pollen-specific nasal symptoms. These biomarkers also enable the prediction of symptom severity before the start of the pollen season.
The American Gastroenterological Association (AGA) has released new guidelines for the management of eosinophilic esophagitis (EoE), a chronic inflammatory disease of the esophagus triggered by allergens. Topical steroids are recommended as a first-line treatment, while proton pump inhibition, diet therapy, and esophageal dilation are ...
The TU Graz pollen measurement system uses machine learning algorithms to analyze pollen samples automatically, reducing the need for manual evaluation. The system is simple, lightweight, energy-saving, and can be implemented at low cost, making it a game-changer for pollination services.
A study warns that AI technology on product labels can be used for both producer benefit and consumer advantage. Researchers propose reformed regulations to prevent producers from manipulating consumers' expectations.
A study published in The Journal of Allergy and Clinical Immunology: In Practice found that children with food protein-induced enterocolitis syndrome (FPIES) are at a higher risk of developing other allergic conditions. Despite this, the researchers did not find a direct causal link between FPIES and these other allergies.
A study of 1,177 mother-infant pairs found exclusive breastfeeding for the first 3 months linked with a lower risk of respiratory allergies and asthma. Breastfeeding duration was insufficient to reduce the risk if not accompanied by family history of asthma.
The COVID-19 outbreak underscores the need for robust research to understand emerging pathogens and develop effective treatments. Researchers are working on various vaccine candidates and therapeutics, including an NIAID-sponsored trial of remdesivir.
Researchers found that over half of patients with reported penicillin allergies could take antibiotics from the same drug class, reducing hospital costs by nearly $21,500. The study's results suggest a multi-disciplinary approach to optimizing therapy in patients with penicillin allergies.
A recent study by the American College of Allergy and Asthma found that most pediatric allergy patients are satisfied with telemedicine visits for allergies and asthma. Among surveyed parents, 37% were more satisfied, while 63% reported equal satisfaction, indicating a positive experience with telemedicine appointments.
Two new studies found that vaginal delivery and exclusive breastfeeding may reduce the risk of developing allergic conditions in children. Meanwhile, a mother's diet during pregnancy and history of allergies can also influence eczema and food allergy development in offspring.
Allergists warn that social media misinformation can lead to incorrect medical decisions for people with food allergies. Dr. David Stukus notes that online 'cures' and at-home testing are often unproven and misleading, while reputable sources should be consulted instead.
A randomized clinical trial in Japan investigated whether avoiding cow's milk formula supplements breastfeeding to decrease the risk of sensitization to cow's milk protein or food allergies. The study involved about 300 newborns and found that this approach may be effective in reducing the risk of these conditions.
A Finnish study found that individuals with more allergic diseases are at higher risk for developing adult-onset asthma, especially among those born after 1940. The research suggests that even one allergic disease can approximately double the asthma risk, while three or more diseases can quadruple it.
The University of Alabama at Birmingham will organize and implement an international, multi-site study to learn more about AFM incidence and progression. The study aims to better understand how the disease develops in children and identify potential risk factors.
Introducing peanut protein regularly can lower a baby's risk of developing a peanut allergy. Canadian Medical Association Journal recommends introducing peanut butter or powdered puff at home between 4-6 months for most babies.