Stuart J. Pocock, a renowned statistician, will receive the TCT Career Achievement Award for his groundbreaking work in interventional cardiology. His research has transformed patient care through evidence-based insights, improving survival and quality of life for heart disease patients worldwide.
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Researchers from the Smidt Heart Institute found that individuals with spherical hearts are 31% more likely to develop atrial fibrillation and 24% more likely to develop cardiomyopathy. The study identified four genes associated with cardiomyopathy and a greater risk of developing atrial fibrillation.
A recent study suggests that cardiac sphericity, or the roundness of the heart, may be a useful indicator for diagnosing cardiovascular conditions. The research used machine learning to analyze medical images and found a link between increased sphericity and future heart troubles.
The Society for Cardiovascular Angiography & Interventions (SCAI) and the Heart Rhythm Society (HRS) released an updated expert consensus statement on transcatheter left atrial appendage closure, focusing on best practices for endovascular devices. The recommendations emphasize operator experience, patient selection, and imaging guidan...
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A new study published in the European Heart Journal shows that using waist-to-height ratio instead of BMI provides a clearer picture of patient outcomes in heart failure. The researchers found that greater adiposity is associated with worse outcomes, including high rates of hospitalization and reduced health-related quality of life.
Supervised exercise training is safe and may improve exercise capacity and quality of life for people with heart failure with preserved ejection fraction (HFpEF). Exercise therapy has been shown to be more effective in improving quality of life compared to medications for this condition.
Researchers found that hematopoietic stem cells use aggrephagy to collect and destroy misfolded proteins, a process that is critical for maintaining stem cell fitness and longevity. Boosting this pathway could help preserve stem cell health and mitigate blood and immune disorders.
The study found substantial drop in laboratory radiation, with most cases producing undetectable radiation exposure to cardiology staff. The new radiation protection system reduces overall room radiation and eliminates head and face exposure, promoting workplace safety.
A recent study published in JAMA demonstrates the effectiveness of a minimally invasive procedure called renal denervation (RDN) to treat uncontrolled hypertension. RDN uses ultrasound energy delivered through a small balloon to denervate the renal artery, reducing sympathetic nerve activity and decreasing blood pressure.
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Children from low-income neighborhoods are more likely to develop preventable heart disease due to high blood pressure, according to a new study. The research highlights the importance of considering neighborhood-related factors when diagnosing hypertension in youth.
A clinical study published in the European Heart Journal found that ghrelin increases the heart's pump capacity in patients with heart failure, improving cardiac output by 28% after two hours of treatment. The treatment also showed a 10% higher pump capacity at follow-up.
A phase 2 study found that ANGPTL3 inhibitor therapy reduced triglycerides by up to 70% in patients with severe hypertriglyceridemia who had previously experienced acute pancreatitis. The treatment, evicanumab-dgnb, also showed potential for cardiovascular prevention by reducing apolipoprotein B levels.
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The prevalence of metabolically healthy obesity (MHO) has been found to increase significantly among U.S. adults over the past two decades, according to a new study published in JAMA Network Open. The research highlights the need for effective strategies to improve metabolic health status and prevent obesity-related complications.
Researchers at Brigham and Boston Medical Center found associations between kidney damage and increased risk of heart disease and death. The study analyzed kidney tissue from 597 adults with chronic kidney disease, linking specific lesions to cardiovascular events.
A virtual care team consisting of physicians and pharmacists improved the adoption of life-saving therapies in patients with heart failure, leading to increased use of evidence-based treatments and better patient outcomes. The strategy was safe and effective, with comparable length of stay and safety events between the groups.
High-dose anticoagulation reduces intubations and deaths by 30% in hospitalized COVID-19 patients, especially those with ARDS. The study found a significant reduction in mortality and need for ICU care among patients treated with therapeutic anticoagulation.
A new study shows that transcatheter mitral valve repair significantly reduces hospitalizations by almost 50 percent and death by nearly 30 percent in heart failure patients with severe mitral regurgitation. The procedure, using Abbott's MitraClip system, improves symptoms, reduces hospitalizations, and leads to longer survival.
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Researchers at NYU Grossman School of Medicine found that automated systems with alert banners increased MRA therapy prescriptions for heart failure patients by 30%. The system aims to improve care and reduce costs by streamlining medical information in one place. The study tested two notification types, finding that banner-like alerts...
The study found that transcatheter edge-to-edge repair achieved a successful repair for nearly 9 out of 10 patients and reduced valve leakage from severe to moderate or less in almost 90% of patients. Patients who underwent the procedure were half as likely to die within one year compared with those in whom the procedure was unsuccessful.
A recent MRI study by the CNIC has established reference values for anatomical and functional parameters in adolescents' hearts, providing a crucial resource for clinical practice. The study involved 123 adolescents and aimed to fill the knowledge gap on 'normal' cardiac parameter values in this age group.
Using a dual-source CT scanner eliminates the need for beta-blockers and decreases nondiagnostic examinations, resulting in shorter CT completion times. The study found no difference in ED length of stay but demonstrated significant benefits in reducing nondiagnostic examinations.
A new review paper from Mayo Clinic outlines how obesity impacts common tests used to diagnose heart disease, such as ECG, CT scan, MRI, and echocardiogram. The study highlights the need for alternative approaches to prevent weight gain in patients with heart disease.
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William L. Lombardi, MD, receives the TCT Geoffrey O. Hartzler Master Operator Award for his technical excellence and leadership in complex coronary disease therapies. He is recognized for developing novel CTO techniques and technologies to improve patient outcomes.
A new cell therapy has demonstrated significant benefits in improving the heart's pumping ability and reducing the risk of cardiovascular death, heart attack, or stroke in patients with chronic heart failure. The therapy, using mesenchymal precursor cells (MPCs), also showed a strong signal in reducing inflammation and improving microv...
A study analyzing over 12,000 patients found that transesophageal echocardiography-guided transcatheter structural cardiac interventions were associated with a major complication rate of 3.6%. The most frequently reported complication was gastrointestinal bleeding.
A new study by the Cleveland Clinic found that high levels of erythritol, a popular artificial sweetener, are associated with an increased risk of heart attack and stroke. Researchers studied over 4,000 people and found those with higher blood erythritol levels were at elevated risk of experiencing a major adverse cardiac event.
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Researchers have found a significant link between frequent marijuana use and an increased risk of coronary artery disease (CAD), with daily cannabis users being about one-third more likely to develop the condition. The study used data from 175,000 people and suggested that cannabis use disorder is associated with a higher risk of CAD.
A recent study found that adverse pregnancy outcomes are largely driven by pre-pregnancy health issues such as diabetes and hypertension. The rate of hypertensive disorders of pregnancy rose by over 50% during the decade, while the shift in age distribution accounted for less than 2% of that change.
Research finds people with insomnia are 69% more likely to have a heart attack compared to those without the sleep disorder. Insomnia is also associated with an increased risk of heart attacks in people with diabetes and those who get less than five hours of sleep per night.
People with technology-assisted pregnancies are twice as likely to develop preeclampsia as those with traditional pregnancies, according to a study. Preeclampsia is a serious pregnancy-related complication that poses risks to the pregnant person and baby.
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A smartphone app-based cognitive behavioral therapy program lowered blood sugar levels and improved health behaviors in patients with diabetes. The study found a clear 'dose effect,' where participants completing more lessons saw greater benefits.
The new clinical document defines the required competencies for interventional cardiology, providing trainees with information to support training across all areas. Trainees must acquire experience working as part of a multidisciplinary team and complete a minimum of 250 procedures.
Researchers found a significant increase in new-onset diabetes after COVID-19 infection, with vaccination prior to infection showing protective effects. The study suggests that COVID-19 infection could be acting as a disease accelerator, amplifying risk for diabetes diagnosis.
Researchers at The Hospital for Sick Children have discovered that dysregulation of energy production is an early sign of heart failure. They found that lysine demethylase 8 (Kdm8) helps maintain balanced energy use, but its suppression leads to changes in metabolism.
Research highlights the intergenerational impact of prepregnancy heart health on offspring, with low pre-pregnancy cardiovascular health linked to pregnancy complications and higher risk for cardiovascular disease. Improving women's heart health before pregnancy could reduce these risks and have a positive impact on future generations.
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A multinational study of over 600,000 heart failure patients found that the disease is relatively fatal, with an average annual death rate of 13%, and results in high healthcare costs. The study also identified new treatment opportunities for heart failure with preserved left ventricular function.
A study at Radboud University Medical Center found that pre-hospital troponin measurements can safely identify low-risk patients with chest pain, reducing the need for hospital visits. The results show a small risk of major adverse cardiac events, but also significant cost savings.
Assistant Professor Tracy Hookway at Binghamton University has received a five-year, $500,000 National Science Foundation CAREER Award to study the interplay between sympathetic and parasympathetic neurons on heart cells. Her research could lead to better understanding of cardiac health, including heart transplants, neurodegenerative d...
A new study by researchers from Lund University in Sweden has found that women with pregnancy complications are at an increased risk of heart disease. The study revealed that women with pre-eclampsia and gestational hypertension had visible atherosclerosis of the coronary arteries, compared to those without complications.
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Preterm birth increases the risk of cardiovascular problems; combining steroids with statins could eliminate negative effects while retaining respiratory benefits. Researchers found that combined therapy improved lung function and reduced cardiovascular issues in rat pups.
A new expert consensus statement proposes a revised PCI treatment algorithm that expands the type of cases that can be performed with no-SOS, considering operator experience and facility preparation. The statement highlights low rates of complications and similar outcomes to PCIs performed at surgical centers.
A study published in JACC: Clinical Electrophysiology found a significant correlation between periodontitis and fibrosis in the left atrium, which can lead to atrial fibrillation. Researchers suggest that periodontal care could aid in comprehensive management of atrial fibrillation.
A new study led by Columbia researchers discovered a link between serotonin and heart valve disease, specifically degenerative mitral regurgitation. The study found that patients taking selective serotonin reuptake inhibitors (SSRIs) were more likely to develop severe mitral regurgitation and require surgery at a younger age.
Researchers identified a panel of novel blood biomarkers associated with sudden cardiac arrest, which have the potential to enhance clinical prediction. Additionally, an AI-powered ultrasound technology can accurately identify coronary artery calcium buildup, potentially replacing CT scans as a diagnostic tool.
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The number of cardiovascular disease-related deaths in the US rose significantly between 2019 and 2020, with Asian, Black and Hispanic populations most affected. The largest single-year increase since 2015 was seen in CVD deaths among these populations, highlighting structural and societal disparities.
A Michigan Medicine study found that hospitals with the highest stroke care designation reported significantly higher rates of stroke detection after TAVR. The study suggests that comprehensive stroke centers are better at detecting smaller strokes, but this does not necessarily mean they are finding more strokes overall.
A recent study found that Black and Hispanic veterans experienced longer wait times for cardiology and orthopedic services compared to white veterans, highlighting racial disparities in healthcare access
Researchers discovered that female and male mouse hearts react uniformly at first to noradrenaline but exhibit differences in recovery time, affecting electrical activity. These findings may contribute to arrhythmia susceptibility between men and women, offering new insights into sex-based responses to stress hormones.
Recent national data analyzed by leading cardiology and cardiothoracic surgical researchers found that the rate of successful repair has reached over 90% in the US, with an extremely low risk of mortality across nearly all age ranges. A novel risk model was developed to predict 30-day outcomes based on patient health conditions.
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A large clinical trial supported by the National Institutes of Health found that two widely used diuretics, furosemide and torsemide, did not differ in improving patient survival when compared. The study suggests a need for better treatments for heart failure patients and highlights the importance of optimizing diuretic doses to improv...
Researchers found that patients with low comorbidity groups who received more frequent phone calls had improved outcomes, including reduced mortality and longer hospital stays. The intervention involved regular calls from nurses to monitor patient response and address any unusual symptoms.
A recent study found that patients treated at centers that don't perform transplants have a 79% higher odds of being denied bridge-to-transplant designation. This change could exacerbate existing disparities in access to heart transplantation, according to the research team.
A new analysis by Cedars-Sinai investigators shows that similar levels of COVID-19 antibodies are reached over an extended period of time in different population groups. Individuals with autoimmune diseases and solid organ transplant patients experience lower long-term antibody levels.
A new study reveals that shockwave intravascular lithotripsy (IVL)-assisted transcatheter mitral valve replacement (TMVR) can effectively treat severely calcified mitral valves in patients with severe stenosis and regurgitation. Post-procedural imaging showed progressive valve frame expansion, increased valve area, and resolution of MR.
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Researchers from Osaka University found that tricaprin supplementation leads to remarkable regression of coronary artery plaque and resolution of symptoms in patients with triglyceride deposit cardiomyovasculopathy. The study's findings provide a novel treatment concept for coronary atherosclerosis.
A new study found that approximately three percent of all bone scan patients have markers of cardiac amyloidosis, which can lead to heart failure and increased mortality. The research highlights the importance of early diagnosis and treatment, as well as potential automated detection methods using machine-learning algorithms.
The procedure requires thorough pre-procedural evaluation and assessment of anatomical and hemodynamic data. Long-term results indicate that TPVR can effectively restore RVOT function, while improving survival rates and reducing the need for reintervention across age groups. Vigilant testing is recommended to avoid rare but serious com...
Researchers from Kyushu University found that evening hot spring bathing is associated with a lower prevalence of hypertension among Japanese older adults. The study analyzed data from over 11,000 residents over 65 and discovered that those who bathed in onsen after 19:00 were 15% less likely to have hypertension.
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Cardiology organizations propose modernizing randomized clinical trials using streamlined approaches, digital technology, and real-world data to enhance efficiency, safety, and innovation. The goal is to improve patient care and address unmet medical needs, particularly for diverse populations.
Researchers will investigate the relationship between heart function and aorta stiffness to identify risk factors for heart failure in Hispanics/Latinos, who are disproportionately affected by this condition. The study aims to develop new methods for predicting and preventing heart failure in underrepresented populations.