Researchers are evaluating two prototype placebo rings in a study to determine their safety and usability for women. The goal is to inform the final design of a dual-purpose ring that can prevent both HIV and unplanned pregnancy for a month at a time.
SourceMATRIX: A USAID Project to Advance the Research and Development of Innovative HIV Prevention Products for Women·TypeRandomized controlled/clinical trial·DateMar 21, 2024
Researchers have developed diverse nanoparticles for cancer therapy, including micelles, liposomes, and hybrid nanoparticles, which can overcome challenges and deliver drugs with enhanced targeting abilities.
SourceSichuan International Medical Exchange and Promotion Association·JournalMedComm – Oncology·TypeSystematic review·DateMar 19, 2024
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers have created molecular crystal motors that move in response to light, using photoisomerization to drive coordinated movements. The motors show remarkable durability and resistance to corrosion, making them suitable for biomedical applications.
Researchers have introduced a more efficient processing technique that enables scalable fabrication of custom microscale particles for applications in drug delivery, microelectronics, and abrasives. This process, called roll-to-roll CLIP, achieves unprecedented fabrication rates while preserving high resolution.
Researchers at MIT developed GastroShield, a sprayable gel that prevents bleeding and leakage from weakened gastrointestinal tissues during endoscopic procedures. The gel forms a protective layer that reinforces tissue integrity and promotes healing.
SourceMassachusetts Institute of Technology·JournalAdvanced Materials·DateMar 12, 2024
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Researchers are developing minimally invasive techniques to repair and regenerate tissue in aortic aneurysms using actively targeted, drug-releasing nanoparticles. The team found that rod-shaped particles with high aspect ratios were selectively taken up by diseased endothelial cells, leading to improved therapy outcomes.
SourceLehigh University·JournalJournal of Biomedical Materials Research·DateMar 4, 2024
Researchers have made a breakthrough in developing genetic treatments for hereditary conditions like cystic fibrosis and inherited vision loss. They created a new type of lipid nanoparticle, called Thio-lipids, that can deliver therapeutic payloads to the lungs and retina.
SourceOregon State University·JournalProceedings of the National Academy of Sciences·DateMar 4, 2024
A study by the University of Tsukuba found that keratin microsphere gel enhanced cell proliferation and gene expression related to hair growth. The gel's stimulatory impact on papilla cells was validated through genetic analysis, demonstrating its potential as a safe and effective hair growth agent.
SourceUniversity of Tsukuba·JournalACS Applied Bio Materials·DateFeb 28, 2024
A survey study reveals primary care pediatricians lack preparedness in managing adolescent OUD, with a notable gap compared to other substance use disorders. The results underscore the importance of workforce training programs to address this critical healthcare issue.
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Researchers optimized a chromium-containing MOF to expand its pore size and surface area, increasing its ability to carry and deliver therapeutic compounds. The puffed-up MOFs showed improved performance as potential drug-delivery vehicles, releasing drugs substantially faster than the original version.
SourceAmerican Chemical Society·JournalACS Applied Bio Materials·DateJan 26, 2024
Researchers developed a new photosensitizer, polphylipoprotein (PLP), to improve photodynamic therapy (PDT) efficacy. PLP selectively induces necrosis in cancer cells by exploiting the autophagy mechanism under starvation, leading to high selectivity and potential efficacy.
SourceUniversity of Tsukuba·JournalCommunications Biology·DateJan 17, 2024
Researchers found a combination treatment involving high doses of radiation and chemotherapy to be safe and effective in treating locally advanced non-small cell lung cancer. The treatment, which includes an adaptive boost plan, showed promising results in improving progression-free survival and reducing toxic side effects.
SourceUniversity of California - Los Angeles Health Sciences·JournalJAMA Oncology·DateJan 11, 2024
A novel synthesis method enables easy linkage of therapeutic oligonucleotides to peptide markers, streamlining the process and making it more accessible and cost-effective. This breakthrough has the potential to produce more effective and targeted RNA-based drugs.
SourceAarhus University·JournalNucleic Acids Research·TypeExperimental study·DateDec 13, 2023
Researchers have designed a nanoparticle-based drug delivery system to target inflammation, addressing issues with conventional anti-inflammatory drugs. The system utilizes targeting moieties to enrich nanoparticles in inflamed tissues, achieving enhanced efficacy.
SourceSichuan International Medical Exchange and Promotion Association·JournalMedComm – Biomaterials and Applications·TypeLiterature review·DateDec 12, 2023
Sky & Telescope Pocket Sky Atlas, 2nd Edition
Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
Scientists at Tokyo Tech developed self-folding polymers to create smaller, safer gadolinium-based contrast agents for cancer diagnosis and neutron capture radiotherapy. These nanosized complexes show enhanced tumor accumulation and penetration, reducing toxicity while increasing MRI performance.
SourceTokyo Institute of Technology·JournalAdvanced Science·TypeExperimental study·DateDec 4, 2023
Researchers at Wayne State University aim to extend the lifespan of infusion pumps and injection ports to minimize tissue damage and maintain site integrity. The project seeks to reduce inflammation and fibrosis caused by insulin phenolic preservatives, leading to improved diabetes management practices.
SourceWayne State University - Office of the Vice President for Research·DateNov 28, 2023
Researchers analyzed FDA and patent records to find that manufacturers extended market exclusivity by filing additional patents after FDA approval and obtaining patents on delivery devices. This resulted in a median of 16 years of protection, surpassing other top-selling small-molecule drugs.
SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateNov 16, 2023
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers from Incheon National University create gelatin patches that generate molecular oxygen to accelerate wound healing. The new hydrogels demonstrate improved coagulation, blood closure, and neovascularization in both in vitro and in vivo experiments.
SourceIncheon National University·JournalComposites Part B Engineering·TypeExperimental study·DateNov 6, 2023
Researchers found that changing treatment can lead to significant improvement in mobility and quality of life for patients with advanced Parkinson's disease. A nationwide registry is planned to develop scientifically sound guidelines for combination therapies.
SourceTechnical University of Munich (TUM)·JournalNeurology·TypeData/statistical analysis·DateNov 6, 2023
Researchers have developed soft implantable fibers that can deliver light to major nerves through the body, allowing for precise illumination of nerve pain. The fibers are flexible and stretch with the body, enabling scientists to study peripheral nerve disorders in animal models without constraining movement.
SourceMassachusetts Institute of Technology·JournalNature Methods·DateOct 19, 2023
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
A major study has found that taking benzodiazepines like Valium and Ativan intermittently instead of continuously can lead to significant reductions in side effects such as falls, hip fractures, hospitalizations, and even death. The research showed a 20% decrease in hip fractures, 33% fewer men's falls requiring hospitalization, and a ...
SourceEuropean College of Neuropsychopharmacology·DateOct 10, 2023
A new study reveals that esketamine nasal spray is effective in treating treatment-resistant depression, with 27.1% of patients achieving remission after 8 weeks compared to 17.6% on quetiapine XR. Long-term data shows sustained remission rates at 21.7% for esketamine NS and 14.1% for quetiapine XR.
SourceChampalimaud Centre for the Unknown·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateOct 4, 2023
Researchers developed statistical models using ultrasound measurements and protein levels to predict stillbirth, neonatal death, or extreme preterm delivery. The findings aim to identify suitable candidates for clinical trials testing novel treatments for fetal growth restriction.
SourceUniversity College London·JournalJournal of Clinical Investigation·TypeObservational study·DateSep 15, 2023
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
A study of 151 patients with functional dyspepsia found that turmeric's curcumin was as effective as omeprazole in reducing symptoms after 28 days. Patients who took the combination treatment showed stronger improvements after 56 days, suggesting curcumin may be a viable alternative to conventional drugs.
SourceBMJ Group·JournalBMJ Evidence-Based Medicine·TypeRandomized controlled/clinical trial·DateSep 11, 2023
A team of Chinese and UK researchers has identified superoxide dismutase 1 (SOD1) as a potential target for reversing drug resistance in ovarian cancer. By using nanoparticles to deliver siRNA that reduces SOD1 levels, the study showed reduced growth and decreased resistance to cisplatin in female mice.
SourceXi'an Jiaotong-Liverpool University·JournalCancer Gene Therapy·TypeExperimental study·DateSep 6, 2023
A weighted lottery system may favor allocation of COVID-19 monoclonal antibody to individuals in disadvantaged neighborhoods and those identifying as Black. However, this approach may also result in lower acceptance rates among Black individuals who receive the drug.
SourceJAMA Network·JournalJAMA Health Forum·DateSep 1, 2023
A new nanogel-based carrier delivers a synthetic thyroid hormone mimick to liver cells, resulting in weight loss and improved cholesterol levels. The treatment also resolves liver inflammation with minimal side effects, offering potential for other liver-based diseases.
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
A study at University of Tsukuba found that pharmacists with higher assertiveness scores are more likely to initiate communication that leads to physicians altering prescriptions. This suggests that effective communication skills can improve the safety of drug therapy.
SourceUniversity of Tsukuba·JournalResearch in Social and Administrative Pharmacy·DateJul 20, 2023
Exposure to commonly prescribed antiseizure medications during pregnancy does not negatively impact neurodevelopmental outcomes in young children. The MONEAD study found that lamotrigine and levetiracetam pose low risks for cognitive effects, with some caution needed for high dosages of levetiracetam.
SourceUniversity of Pittsburgh·JournalThe Lancet Neurology·DateJul 19, 2023
Scientists have teamed up to improve drug delivery by designing more effective lipid nanoparticles. Their latest study documents how high-throughput workflows can produce and characterize LNPs at record speed, with neatly ordered structures leading to better silencing of faulty genes in human neurons.
SourceDOE/Lawrence Berkeley National Laboratory·JournalACS Nano·DateJul 17, 2023
Researchers at Tel Aviv University have developed a novel approach to fight cancer by inducing cancer cells to produce a toxic protein using mRNA molecules. The treatment was successful in eliminating 44-60% of cancer cells in animal models, with no damage to healthy cells.
SourceTel-Aviv University·JournalTheranostics·DateJul 2, 2023
Scientists create optically controllable liposomes called LiDLs, which can selectively release contents inside cells upon exposure to acidic pH induced by green light. The researchers demonstrated that LiDLs efficiently deliver substances without causing side effects, showcasing exceptional extracellular stability.
SourceOkayama University·JournalChemical Communications·TypeExperimental study·DateJun 28, 2023
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
Recent studies in the New Journal of Pharmaceutical Analysis feature novel diagnostic tools, RNA sequencing-based workflows, and mechanical property evaluations to enhance cancer and cardiovascular disease treatment outcomes. These innovations aim to improve the therapeutic effect of drugs and promote personalized medicine.
SourceCactus Communications·JournalJournal of Pharmaceutical Analysis·TypeExperimental study·DateJun 21, 2023
Researchers have designed new light-responsive membrane carriers for the translocation of peptide cargos inside living cells, offering a promising strategy for remotely controlled delivery of large biomolecules. The light-triggered system utilizes azobenzene units to control the transport of cationic peptides across lipid membranes.
SourceCenter for Research in Biological Chemistry and Molecular Materials (CiQUS)·JournalJournal of the American Chemical Society·DateJun 14, 2023
A decision analytical model study found that sustained public health interventions can reduce opioid-related overdose deaths. Implementing medications for opioid use disorder and increasing naloxone supply were key factors in reducing death rates.
SourceJAMA Network·JournalJAMA Network Open·DateJun 9, 2023
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
A new research centre will focus on developing new types of RNA medicine for treating metabolic diseases. The centre, led by Professor Jørgen Kjems at Aarhus University, aims to create targeted treatments for conditions like diabetes and atherosclerosis.
A novel gene delivery procedure was successfully applied to baboons, achieving therapeutic levels of human factor IX gene expression lasting up to 200 days. The study demonstrated the efficacy of repeated hydrodynamic gene delivery into the same liver lobes, with no significant adverse events observed.
SourceNiigata University·JournalMolecular Therapy — Nucleic Acids·DateJun 7, 2023
A Canadian study found that eliminating out-of-pocket medication expenses for patients with cost-related nonadherence results in lower healthcare spending over three years. The analysis suggests that reducing medication costs could lead to significant savings in the overall healthcare system.
SourceJAMA Network·JournalJAMA Health Forum·DateMay 26, 2023
Researchers have developed new methods to analyze dry-coated drug particles using 3D Raman mapping, which can effectively slow down dissolution rates. Another study introduces a novel technique for detecting complex traditional Chinese medicines, preventing adulteration and counterfeiting.
SourceCactus Communications·JournalJournal of Pharmaceutical Analysis·TypeExperimental study·DateMay 24, 2023
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
A nationwide analysis of prisoner healthcare incidents in England reveals medication-related harm as a major issue, with staff mistakes being the most common cause. The researchers recommend prioritizing timely access to healthcare services, improving processes to mitigate medication-related harm and increasing remote appointments.
SourceSAGE·JournalJournal of the Royal Society of Medicine·DateMay 17, 2023
Researchers at MIT have designed new 'smart' sutures that can deliver drugs or sense inflammation after surgery. The bioderived sutures use hydrogel coatings to detect early warning signs of complications, such as Crohn's disease, and can also release therapeutic molecules to promote healing.
SourceMassachusetts Institute of Technology·JournalMatter·DateMay 16, 2023
Patients using medical cannabis reported sustained improvements in health-related quality of life in the study. Adverse events were common but rarely serious, highlighting the need for caution when prescribing medical cannabis.
SourceJAMA Network·JournalJAMA Network Open·DateMay 9, 2023
Scientists have identified a novel mechanism of gel formation in synthetic polymers, which leads to the creation of worm-like structures. This breakthrough has significant implications for biofabrication and could lead to the development of new medical implants, contact lenses, and other applications.
SourceUniversity of Würzburg·JournalACS Nano·TypeExperimental study·DateApr 27, 2023
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers discovered that gut bacteria's F-pili are stronger in harsh conditions, enabling efficient gene transfer and biofilm formation. The findings highlight the challenge of combating antibiotic resistance and suggest exploiting similar molecular properties for precise drug delivery.
SourceImperial College London·JournalNature Communications·DateApr 21, 2023
Scientists discover carbonated water's impact on low-methoxy pectin hydrogel formation and properties. The study shows that CO2 from carbonated water increases mechanical strength and gelation rate of hydrogels.
SourceTokyo University of Science·JournalACS Omega·TypeExperimental study·DateApr 13, 2023
The new American Heart Association scientific statement emphasizes the importance of including non-biological factors and social determinants in CVD risk assessment for women. These factors include economic stability, neighborhood safety, education level, and access to quality healthcare, which disproportionately affect women from dive...
SourceAmerican Heart Association·JournalCirculation·DateApr 10, 2023
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers have developed a new ear tube design that combines liquid-infused materials with optimized geometry to improve treatment outcomes for patients with ear infections. The design enables better performance and reduces complications such as impaired hearing and scarring of the eardrum.
SourceWyss Institute for Biologically Inspired Engineering at Harvard·JournalScience Translational Medicine·TypeExperimental study·DateApr 5, 2023
Researchers used computational modeling to identify ultrastable MOF structures, which could be useful for gas storage and catalysis. The study found that about 10,000 of the predicted structures were stable enough for these applications, with high deliverable capacities for methane.
SourceMassachusetts Institute of Technology·JournalMatter·TypeComputational simulation/modeling·DateApr 4, 2023
Researchers at Rice University have created a new technology called PULSED that can deliver time-released drugs and vaccines for extended periods. The technology uses high-resolution 3D printing and soft lithography to produce microcylinders made of biodegradable polymers, which can be loaded with drugs and release them over time.
SourceRice University·JournalAdvanced Materials·TypeExperimental study·DateApr 3, 2023
Researchers have developed a microneedle-based drug delivery technique for plants, which can precisely deliver controlled amounts of agrochemicals to specific plant tissues. This method has the potential to improve crop quality and disease management while minimizing resource wastage and environmental contamination.
SourceSingapore-MIT Alliance for Research and Technology (SMART)·JournalAdvanced Materials·TypeExperimental study·DateMar 14, 2023
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
A new cutaquig study found that increasing infusion volume per site resulted in a reduction of injection sites, while increasing infusion rates decreased infusion duration. The research also showed that dosing every other week demonstrated equivalency to trough levels with weekly dosing.
SourceYankee Public Relations·JournalJournal of Allergy and Clinical Immunology·TypeObservational study·DateMar 6, 2023
Gene therapy using CRISPR-Cas9 lipid nanoparticles has been shown to be highly effective in reducing target protein expression in mice. The new delivery system increases the efficiency of in vivo gene therapy, paving the way for safe and effective treatment.
SourceHokkaido University·JournalJournal of Controlled Release·TypeExperimental study·DateMar 1, 2023
Scientists at Aarhus University and Berkeley Laboratory developed a method called RNA origami to design artificial RNA nanostructures. The technique allowed for the discovery of rules and mechanisms for RNA folding that will make it possible to build more ideal RNA particles for use in RNA-based medicine.
SourceAarhus University·JournalNature Nanotechnology·TypeExperimental study·DateFeb 27, 2023
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
A fast-dissolving insert containing TAF and EVG was found safe and effective in preventing HIV transmission through anal sex. The study delivered high levels of the drugs to rectal tissue and fluid, with potential protection for up to three days after use.
New materials called gas-entrapping materials (GeMs) can carry high concentrations of therapeutic gases directly into tissues, including tumors. This improves the effectiveness of standard chemotherapy and radiation treatments in mouse models of prostate cancer and sarcoma.
SourceUniversity of Iowa Health Care·JournalAdvanced Science·TypeExperimental study·DateFeb 2, 2023
Researchers at UW-Madison developed silica nanocapsules that can carry CRISPR tools across the blood-brain barrier, enabling brain-wide gene editing for disorders like Alzheimer's and Parkinson's. The technology has potential for non-invasive delivery of gene therapies.
SourceUniversity of Wisconsin-Madison·JournalAdvanced Materials·DateJan 19, 2023
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
A new software program developed by Duke Ph.D. student Dan Fu lets users create 3D structures made of DNA, including tiny vases, bowls, and hollow spheres. The software relies on a way to build with DNA described in 2011 by Hao Yan, which works by coiling a long DNA double helix into concentric rings to form the contours of the object.
SourceDuke University·JournalScience Advances·TypeExperimental study·DateDec 23, 2022
Researchers have developed chemically modified nanosheets that can effectively deliver drugs to diseased cells, reducing side effects. The nanosheets, made from molybdenum disulphide, can exchange natural thiols with attached ligands, allowing for targeted drug delivery.
SourceIndian Institute of Science (IISc)·JournalACS Nano·DateDec 8, 2022
Rice University researchers are developing implants that can produce and deliver monoclonal anti-HIV antibody therapeutics for at least a year. The project aims to reduce the cost and improve the logistics of HIV treatment, making it more accessible and beneficial for patients worldwide.
Researchers at Tokyo University of Science have developed a unique 3D COF with scu-c topology, exhibiting efficient gas adsorption and drug delivery capabilities. The material has been shown to exhibit excellent hydrogen and methane adsorption properties.
SourceTokyo University of Science·JournalACS Applied Materials & Interfaces·TypeExperimental study·DateDec 5, 2022
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.