A study found that genetic variants near ERAP2 and TICAM2 provided protection against Yersinia pestis, the bacterium responsible for the Black Death. These variants were also associated with improved detection and resistance to other pathogens, but at a cost: increased risk of autoimmune disorders like Crohn's disease.
SourceCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign·JournalNature·TypeExperimental study·DateDec 8, 2022
Research emphasizes the importance of ethnically diverse prostate cancer genomics data and accessible genetic testing. Variations in genomic landscape of prostate cancer were observed in Chinese men compared to Western cohorts, with lower mutation rates in driver genes such as TP53 and PTEN.
SourceEuropean Society for Medical Oncology·JournalAnnals of Oncology·DateNov 28, 2022
A genetic test known as chromosomal microarray analysis (CMA) may be able to identify the cause of Sudden Infant Death Syndrome (SIDS) or its counterpart in older children, known as Sudden Unexplained Death in Childhood (SUDC). CMA identified deletions or duplications of DNA segments in 14% of deceased infants and toddlers up to 28 mon...
SourceBoston Children's Hospital·JournalAdvanced Genetics·DateNov 7, 2022
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers discover exceptional individual with 12 tumors, shedding light on early detection methods and immune system response. Single-cell analysis technology shows promise in identifying cells with tumor potential before symptoms appear.
SourceCentro Nacional de Investigaciones Oncológicas (CNIO)·JournalScience Advances·TypeCase study·DateNov 2, 2022
Researchers at MIT have developed a new control system for synthetic genes that can precisely regulate protein production in mammalian cells. The system uses CRISPR proteins to activate target genes and can be tuned to produce specific quantities of proteins, such as monoclonal antibodies.
SourceMassachusetts Institute of Technology·JournalNature Communications·DateNov 1, 2022
Researchers at Rice University have developed a procedure to quantify unintended changes that accompany on-target CRISPR-Cas9 gene editing, potentially threatening the efficacy and safety of therapies. The new method uses single-molecule sequencing with unique molecular identifiers to detect large deletions, insertions, and chromosomal...
SourceRice University·JournalScience Advances·TypeExperimental study·DateOct 24, 2022
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A novel genetic analysis by University of Ottawa researchers reveals that climate change could lead to an increased risk of viral spillover in the High Arctic. This increased risk may result in new viruses infecting previously uninfected hosts, potentially leading to emerging pandemics.
SourceUniversity of Ottawa·JournalProceedings of the Royal Society B Biological Sciences·TypeComputational simulation/modeling·DateOct 19, 2022
A recent study identifies a specific gene, GNL3, that regulates neural proliferation in response to lithium, which is used to treat bipolar disorder. This gene plays an important role in brain function and has been implicated in risk for bipolar disorder, schizophrenia, and inter-individual variations in intelligence.
SourceElsevier·JournalBiological Psychiatry·TypeExperimental study·DateOct 18, 2022
A recent poll reveals that 48% of people aged 50-80 have purchased at least one home health test, including COVID-19 and DNA tests. Notably, 82% of older adults express interest in future medical tests at home, while 90% agree to share results with their healthcare provider.
SourceMichigan Medicine - University of Michigan·TypeSurvey·DateOct 13, 2022
Researchers discovered that plasmids can linger in the nose of lab workers for weeks, interfering with clinical diagnostic tests. The study highlights the importance of considering occupational exposure in diagnosis and treatment.
SourceAmerican Society for Microbiology·JournalMicrobiology Spectrum·DateOct 13, 2022
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers have developed genetic testing to diagnose cardiomyopathy in children, identifying those at risk of heart failure and requiring a transplant. The test provides precise clinical diagnosis, enabling targeted treatment options and reducing the need for life-threatening interventions.
SourceCentenary Institute·JournalCirculation Genomic and Precision Medicine·TypeExperimental study·DateOct 12, 2022
A new variant of adeno-associated virus (AAV) shows significant improvement in delivering gene therapies to the central nervous system (CNS), potentially treating brain cancers and genetic diseases. The AAV variant, identified as CPP.16, demonstrates enhanced delivery efficiency across the blood-brain barrier in preclinical models.
SourceBrigham and Women's Hospital·JournalNature Biomedical Engineering·TypeObservational study·DateOct 10, 2022
A new genetic test called PancreaSeq accurately classifies pancreatic cysts as potentially cancerous or benign, improving the accuracy of diagnoses compared to current guidelines. The test distinguishes between different types of cysts with higher accuracy than traditional forms of surveillance and current pancreatic cyst guidelines.
SourceUniversity of Pittsburgh·JournalGastroenterology·TypeObservational study·DateOct 5, 2022
A new research paper has demonstrated that psychological factors, such as feeling unhappy or being lonely, add up to 1.65 years to one's biological age, significantly impacting overall health and longevity.
SourceImpact Journals LLC·JournalAging-US·TypeData/statistical analysis·DateOct 3, 2022
A new study found that arbitrary age limits and rules on genetic testing for amyotrophic lateral sclerosis (ALS) could be missed, leading to thousands of potential cases going undetected. The researchers argue that genetic testing should be open to all patients with ALS, regardless of age or family history.
SourceKing's College London·JournalBrain·TypeObservational study·DateSep 26, 2022
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
A new study found that integrating genetic testing into electronic health records (EHRs) significantly reduces clinician workload, with average savings of 45 minutes per day. Clinicians can now order and manage tests directly through the EHR, resulting in reduced time spent on clerical work.
SourceUniversity of Pennsylvania School of Medicine·JournalGenetics in Medicine·TypeObservational study·DateSep 21, 2022
Researchers suggest a new approach for regulating genetically engineered (GE) crops by examining the specific characteristics of the crop itself. The '-omics' methods can be used to scan new crop varieties for unexpected DNA changes, eliminating the need for safety testing if the product is substantially equivalent to existing varieties.
SourceNorth Carolina State University·JournalScience·TypeCommentary/editorial·DateSep 1, 2022
A new study from Lund University reveals that the most common analytical method in population genetics is deeply flawed, leading to incorrect results and misconceptions about ethnicity and genetic relationships. The method has been used in hundreds of thousands of studies, including medical genetics and commercial ancestry tests.
SourceLund University·JournalScientific Reports·DateAug 30, 2022
Researchers at Brain Chemistry Labs have developed a new blood test for ALS using microRNA sequences, which accurately discriminated between patients and healthy individuals. The test works even with varying environmental conditions, offering hope for rapid diagnosis and improved patient outcomes.
SourceBrain Chemistry Labs·JournalJournal of the Neurological Sciences·TypeExperimental study·DateAug 30, 2022
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
A new study from Lund University reveals that PCA, a widely used statistical method in population genetics, is deeply flawed. The method can produce flexible and unreliable results, leading to misconceptions about ethnicity and genetic relationships.
SourceLund University·JournalScientific Reports·DateAug 30, 2022
The study analyzed blood samples from bottlenose dolphins in the northern Gulf of Mexico, finding changes in gene expression related to immune response and oxidative stress. The results provide new insights into the health impacts of oil spills on marine life.
Researchers at Terasaki Institute create micro-organospheres for direct viral infection, immune cell penetration, and high-throughput therapeutic drug screening. The technology holds promise for personalized medicine, tumor therapy and rapid drug testing.
SourceTerasaki Institute for Biomedical Innovation·JournalStem Cell Reports·TypeExperimental study·DateAug 18, 2022
Researchers analyzed genetic data from nearly 43,000 people with autism and identified a novel group of inherited genes of moderate effect. The study shows that these genes contribute to autism through inherited variants and are associated with other neurodevelopmental disorders.
SourceSimons Foundation·JournalNature Genetics·TypeData/statistical analysis·DateAug 18, 2022
Scientists developed a same-day test to identify abnormal fetal chromosomes using prenatal tests and tissue from miscarriage or biopsies. The STORK test shows promise in diagnosing genetic causes of miscarriage and streamlining IVF, potentially saving time and cost.
SourceNIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development·JournalNew England Journal of Medicine·DateAug 17, 2022
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
A study published in Patterns shows that five digital medicine companies share browsing data related to health topics with Facebook for lead generation and advertising purposes. The researchers found that two companies targeted ads consistent with their own privacy policies, while the other three did not comply with their policies.
SourceCell Press·JournalPatterns·TypeSurvey·DateAug 15, 2022
The NCI-backed Molecular Targets Platform streamlines and catalyzes drug development by integrating pediatric cancer targets and pathways. This platform empowers researchers, pharmaceutical companies, and advocacy groups to accelerate the pace of drug development for pediatric cancer.
SourceChildren's Hospital of Philadelphia·DateAug 4, 2022
A VA study found nearly identical genetic variations contributing to coronary heart disease risk across major racial and ethnic backgrounds. The findings suggest that other factors like access to healthcare contribute to higher heart disease rates in certain populations.
SourceVeterans Affairs Research Communications·JournalNature Medicine·TypeData/statistical analysis·DateAug 3, 2022
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A new Bayesian method and genomic data analysis reveal strong statistical support for the 'Pleistocene aggregate island complex (PAIC) model', a theory suggesting species diversification during ice ages. This study tested the PAIC model in two genera of lizards, each with species found only in the Philippines.
SourceUniversity of Kansas·JournalProceedings of the National Academy of Sciences·DateJul 20, 2022
A study found that pharmacogenomic testing can help providers avoid prescribing antidepressants with undesirable outcomes. The test, which analyzes genes related to drug metabolism, resulted in a significant improvement in depression symptoms compared to usual care.
SourceVeterans Affairs Research Communications·JournalJournal of the American Medical Association·TypeRandomized controlled/clinical trial·DateJul 12, 2022
A study reveals how consumer DNA testing is changing the way people seek information about genetic relatives in donor conception, including ethnic estimates and tracing half-siblings. The widespread availability of commercial DNA databanks is transforming the landscape of donor conception.
SourceEuropean Society of Human Reproduction and Embryology·TypeNews article·DateJul 6, 2022
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
Researchers investigate regulatory frameworks governing preimplantation genetic testing in Japan, the UK, and Western Australia. The study highlights the need for a multidisciplinary approach to evaluate disease severity and make informed decisions about treatment.
SourceOsaka University·JournalHuman Genomics·TypeCase study·DateJul 6, 2022
A preliminary study published in eLife suggests that sperm screening can identify potentially harmful new genetic mutations and help prevent them from being passed on to offspring. The study found that 55 mutations were detected in the men's sperm, including 15 passed on to an embryo.
A heat-loving bacterium's Cas13 protein enables specific detection of SARS-CoV-2 and other viruses in a one-pot assay. The technology has been patented and clinically validated, with the aim of mass production and commercialization.
SourceKing Abdullah University of Science & Technology (KAUST)·JournalProceedings of the National Academy of Sciences·DateJul 3, 2022
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A new digital PCR technique helps identify mutations in malaria parasites that evade detection by rapid tests, reducing false negatives. This allows for more accurate selection of diagnostic tests tailored to specific regions.
Researchers have developed an app to help doctors identify patients with chronic lymphocytic leukemia (CLL) at risk of developing infections, allowing for earlier treatment. The app uses blood test results and genetic data to predict patient risk, improving treatment outcomes and reducing pressure on the healthcare system.
SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalCommunications Medicine·TypeCase study·DateJun 24, 2022
Researchers used nanopore sequencing to detect specific genomic disorders in a fraction of the time it takes traditional testing. The study showed that diagnosis of larger chromosomal alterations could be made in one day, while smaller CNVs took two days.
SourceElsevier·JournalJournal of Molecular Diagnostics·TypeExperimental study·DateJun 13, 2022
Researchers evaluate Jumpcode Genomics CRISPRclean technology for transforming pandemic response through highly sensitive testing. The assay quickly identifies variant strain types and individual host responses in a single workflow.
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A new study examines mathematical models designed to draw inferences about how evolution operates at the level of populations of organisms. The researchers conclude that such models must be constructed with care, avoiding unwarranted initial assumptions and weighing existing knowledge.
SourceArizona State University·JournalPLOS Biology·TypeCommentary/editorial·DateJun 6, 2022
Early genetic testing and precision medicine lead to improved seizure control, enabling infants with epilepsy to leave the hospital sooner. A study at Ann & Robert H Lurie Children's Hospital of Chicago found a significant reduction in hospital stay time for babies with epilepsy who underwent genetic testing.
SourceAnn & Robert H. Lurie Children's Hospital of Chicago·JournalPediatric Neurology·DateJun 6, 2022
Researchers emphasize the need for targeted recruitment to make genetic tests clinically useful for non-European groups. By addressing cultural concerns and underrepresentation, efforts can reduce the incidence of variants of uncertain significance (VUS) in genetic databases.
SourceCell Press·JournalAmerican Journal of Human Genetics·TypeCommentary/editorial·DateJun 2, 2022
Researchers developed a genetic test that diagnoses primary immunodeficiency disorders (PID), revealing inherited genetic defects in nearly half of patients. The test uses next-generation sequencing technology to identify specific gene variants associated with PID, enabling targeted treatment and earlier intervention for family members.
SourceElsevier·JournalJournal of Molecular Diagnostics·TypeExperimental study·DateMay 23, 2022
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A large study has found six predictors that can help determine the optimal lithium dose for patients with bipolar disorder. The predictors include age, sex, kidney function, and medication use. The researchers hope to develop a digital app to aid psychiatrists in finding the right dose.
SourceKarolinska Institutet·JournalThe Lancet Psychiatry·DateMay 12, 2022
A study published in Med found that the human microbiome's variation explains different patient responses to statins. The researchers discovered a Bacteroides enriched microbiome with lower diversity was associated with stronger LDL-lowering effects but greater disruption of blood glucose levels.
SourceInstitute for Systems Biology·JournalMed·TypeComputational simulation/modeling·DateMay 11, 2022
Researchers at Texas A&M AgriLife Research have developed a mechanism to make temporary genetic changes in mosquitoes that self-delete over time. This technology has the potential to help manage mosquito populations and prevent vector-borne diseases like West Nile virus without permanently altering wild populations' genetic makeup.
SourceTexas A&M AgriLife Communications·JournalProceedings of the National Academy of Sciences·DateMay 2, 2022
The US Multisociety Task Force on Colorectal Cancer recommends genetic evaluation and personalized surveillance plans for patients with hamartomatous polyps. Genetic testing is critical in cancer prevention, allowing for tailored cancer surveillance to prevent progression and save lives.
SourceAmerican Gastroenterological Association·JournalGastroenterology·DateApr 26, 2022
A study found that 12% of recurrent ductal carcinoma in situ (DCIS) cases were new primary lesions unrelated to the original tumor. These findings suggest that genetic biomarkers for predicting recurrence may not be effective for all patients.
SourceAmerican Association for Cancer Research·DateApr 10, 2022
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers analyzed genomic profiles of over one million cells from 1,000 people, identifying a link between specific genes and immune cell types in autoimmune diseases. The discovery could lead to tailored treatments and refine clinical trials.
SourceGarvan Institute of Medical Research·JournalScience·DateApr 7, 2022
The Victoria's Secret Global Fund for Women's Cancers has awarded five female researchers for their groundbreaking work on breast and gynecologic cancers. The recipients will receive a $100,000 honorarium and be invited to participate in a broader women's cancers grant program.
SourceAmerican Association for Cancer Research·DateMar 31, 2022
A recent study published in Translational Psychiatry found that pharmacogenetic testing significantly improved symptoms in patients with treatment-resistant depression. The study involved 276 patients and showed a nearly two-fold increase in remission rates compared to treatment as usual.
SourceCentre for Addiction and Mental Health·JournalTranslational Psychiatry·DateMar 29, 2022
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
A report by the British Pharmacological Society and Royal College of Physicians recommends integrating pharmacogenomic testing to ensure medicines work safely and effectively for individual patients. The UK is a world leader in genomic medicine, and expanded testing would further demonstrate this leadership.
SourceBritish Pharmacological Society·JournalBritish Journal of Clinical Pharmacology·TypeCommentary/editorial·DateMar 28, 2022
A recent brain imaging study has found evidence of weakening connections between key brain areas in adolescents at high genetic risk of developing bipolar disorder. This study suggests that early intervention strategies may be effective in preventing the progression towards major changes in the brain.
SourceUniversity of New South Wales·TypeCase study·DateMar 28, 2022
Carly Peterson, a genetic counseling graduate student, received the 2022 ACMG Foundation Carolyn Mills Lovell Genetic Counselor Award. Her platform presentation explored parenting stress in raising children with sex chromosome aneuploidies, using data from the eXtraordinarY Babies Study.
SourceAmerican College of Medical Genetics and Genomics·DateMar 23, 2022
The ACMG Foundation presented four Next Generation Fellowship Awards to outstanding individuals in medical genetics and genomics. Ibrahim Elsharkawi and Jessica Priestley received the awards for their dedication to biochemical genetics, with support from Bionano Genomics, Spark Therapeutics, Takeda, Sanofi-Genzyme, and Pfizer.
SourceAmerican College of Medical Genetics and Genomics·DateMar 23, 2022
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
Dr. Kushani Jayasinghe, a nephrologist and trainee in clinical genetics, received the 2022 Richard King Award for her article on genomic testing in patients with suspected monogenic kidney disease. The award recognizes high-quality research published in Genetics in Medicine by trainees.
SourceAmerican College of Medical Genetics and Genomics·DateMar 23, 2022
A new study confirms that abnormalities in the GDF15 gene are involved in hyperemesis gravidarum, a condition causing severe nausea and vomiting during pregnancy. The discovery may lead to targeted treatments and improved care for women with HG.
SourceKeck School of Medicine of USC·JournalBJOG An International Journal of Obstetrics & Gynaecology·TypeExperimental study·DateMar 16, 2022
A study has decoded the DNA of the Arabian Oryx, a vulnerable species that was on the brink of extinction. The researchers analyzed the genetic data to inform breeding programs and found moderate diversity in the population's gene pool.
SourceUniversity of Sydney·JournalRoyal Society Open Science·DateMar 15, 2022
The study identifies nine key pathways that seem to be crucial in developing Parkinson's disease, some of which have not been linked before. The findings improve scientists' understanding of genetic risk factors for developing the disease and pave the way for personalized medicine.
SourceUniversity of Auckland·JournalBrain·TypeMeta-analysis·DateMar 14, 2022
Researchers have genetically engineered a rat model of Down syndrome to test new therapies and explore the condition's unique genetics. The rats exhibit cognitive impairments, anxiety, and hyperactivity similar to humans with Down syndrome, providing a valuable tool for medical research.
SourceJohns Hopkins Medicine·JournalAmerican Journal of Human Genetics·DateMar 14, 2022
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers at Kyoto University have identified a genetic mutation causing albinism in wallabies, tracing it to an inserted retrovirus gene. The study found that the mutation was caused by a copy of the HIV-like virus inserted into the host's genome.
SourceKyoto University·JournalGenome·TypeExperimental study·DateMar 10, 2022
Researchers at Clemson University have identified a genetic variation associated with congenital idiopathic megaesophagus (CIM) in German shepherd dogs, which is often fatal if left untreated. A genetic test using melanin-concentrating hormone receptor 2 and dog's sex can predict the risk of CIM with 75% accuracy.
SourceClemson University·JournalPLOS Genetics·TypeData/statistical analysis·DateMar 10, 2022