Articles tagged with Brain Development
Research finds that living in violent neighborhoods can alter a child's brain to detect threats more easily, leading to poorer mental health. Nurturing parents can help protect kids from these detrimental effects by reducing exposure to community violence and promoting resilience.
A recent study of 2,261 infants found no significant adverse effects on neurodevelopment after in utero exposure to COVID-19 vaccination. The research suggests that maternal COVID-19 vaccination is safe for infant development up to 18 months.
A Singaporean study found that children exposed to elevated levels of early life adversity exhibit an accelerated pattern of brain development during preschool years. This accelerated pace may lead to adverse cognitive and mental health outcomes. The study suggests that early intervention may be effective in preventing these consequences.
A new study found that changes in brain function, specifically the auditory sensory memory system, may be a potential biomarker for Batten disease. Researchers measured brain activity using electroencephalography (EEG) and found a decline in response as the disease progressed.
Scientists have developed mini-brains from human fetal brain tissue that self-organize in vitro. These lab-grown organoids can study brain development and disease, including brain tumors. They offer a valuable means to untangle the complex network of molecules involved in directing brain development.
Researchers from UC Davis School of Medicine and MIND Institute found that imbalances in folic acid and vitamin B12 can alter brain development in mice. High folic acid intake, even within recommended guidelines, may cause neurodevelopmental issues in offspring.
The brain's reaction to unexpected sounds changes as it matures, with different regions developing at different times. The study found that the cerebral cortex takes longer to mature than expected, around the early 20s in human years, and is influenced by experience.
Neuronal activity stimulates gene expression in human brain cells by influencing transcription factors and chromatin modifiers, particularly CREB and CBP. The interaction between CREB and DNA requires prior acetylation mediated by CBP to activate gene expression.
Researchers found that inhibitory neurons in the entorhinal cortex continue to migrate and build new connections until age two, contributing to neuroplasticity periods and potential susceptibility to Alzheimer's disease.
A recent study published in NeuroImage found that physically active individuals experienced less decline in entorhinal cortex thickness over a seven-year period. Cognitive reserve is also boosted through regular mental stimulation, suggesting that brains can be trained like muscles to counteract age-related decline.
Researchers have mapped the lineage of neural stem cells in the superior colliculus, revealing an exceptional capacity to generate different types of neurons. The study also found that neural stem cells retain their ability to produce any type of neuron until the end of development.
Researchers discovered how biological information travels between mothers and babies during pregnancy. Microscopic extracellular vesicles, produced by placental cells, act as a protective mechanism transporting important biological information to emerging neurons.
Researchers found that humans are born with brains at a typical development level for similar primate species, but grow much larger and more complex after birth. This challenges the prevailing understanding of evolutionary human brain development.
A review of 23 years of neuroimaging research finds that screen time affects the pre-frontal cortex and other brain regions involved in executive functions, memory, and processing. Digital experiences may shape children's brains and influence cognitive development, with both positive and negative impacts.
A new study suggests that hormonal birth control used by adolescents may influence the development of their brain, leading to altered risk assessment. The researchers found increased myelination and decreased immune cells in the brains of treated rats, while also exhibiting signs of impulsivity in behavior tests.
A new study in Nature Communications presents a large-scale chart of cognitive development in teens, revealing that executive function usually matures by 18 years old. The findings have significant implications for psychiatrists, neuroscientists, parents, educators, and the judicial system.
Researchers have discovered axonal dysregulation in the prenatal brain as a mediator of genetic risk for schizophrenia. The study used induced pluripotent stem cells and three-dimensional brain organoids to identify key genes involved, including CYFIP1, which is highly expressed in microglia.
A large study of 91,460 mother-offspring pairs found no link between prenatal corticosteroid and beta-2 adrenergic agonist exposure and offspring neurodevelopmental issues. The findings suggest these medications are safe for pregnant individuals with asthma.
Researchers at King's College London are studying the effects of maternal prenatal exposure to COVID-19 infection on children's brain development. The six-year study will explore how the maternal immune system affects fetal brain development and identify potential impacts on childhood outcomes.
Brazilian researchers found that Zika-infected mice with microcephaly have lower Ndel1 enzyme activity, which plays a key role in neuron differentiation and migration. The study suggests that Ndel1 may be a biomarker for early diagnosis of microcephaly and offers hope for treatment options.
Two parallel projects publish detailed cell atlases of the adult human brain and brain development, revealing over 3,000 cell types, including new insights into brain diseases and potential therapeutic targets. The freely available brain atlases will enable researchers to compare healthy brains with diseased ones.
Researchers created the first 'multiome' atlas of brain cell development in the human cerebral cortex, revealing specific changes in chromatin structure that precede gene expression. The study pinpointed regions associated with genes linked to neuropsychiatric disorders like schizophrenia and bipolar disorder.
A new AI-powered app can detect autism in children with high accuracy, capturing a wide range of behavioral characteristics beyond eye movements. The app provides detailed information on which indicators led to its conclusions and why, enabling healthcare providers to make informed decisions.
A new study review found children from families with low incomes and families of color are exposed to more neurotoxic chemicals, leading to greater harm on brain development. This disparity is attributed to their neighborhoods being located near factories, chemical plants, highways, and agricultural fields where pesticides are applied.
Exposure to plasticizers during pregnancy has been linked to smaller total gray matter in the brains of children at age 10. Additionally, maternal exposure to certain phthalates is associated with lower child IQ at age 14. The relationship between exposure and lower IQ is partially influenced by total gray matter volumes.
A UMass Amherst neuroscientist is mapping the brain of a sea slug to study how neurons are added to functional neural circuits, shedding light on how this process contributes to neurological conditions. The project aims to provide an unprecedented look at brain development and potentially inform human brain development.
A study by researchers at the University of Tokyo found that the presynaptic Ube3a E3 ligase molecule plays a key role in eliminating neural synapses. This discovery offers insights into developmental disorders such as Angelman syndrome and autism spectrum disorders.
A new study from the University of Toronto finds that cyberbullying is associated with binge eating, weight gain worries and body image distress among 10-14 year olds. The study suggests that limiting social media that encourages eating disorders and appearance comparisons can help prevent these issues.
A new Stanford-led study shows that adding zinc to farmland soil can help prevent childhood stunting, a condition due to chronic undernutrition that is associated with poor brain development and long-lasting harmful consequences. The researchers found that the presence of zinc in soil helps prevent stunted childhood growth.
The Thriving Kids Brain Builders initiative aims to bridge the gap between research and practical application, ensuring all children have access to support for brain development. The project offers a free online course, 'Understanding Brain Development', developed by QBI and Emerging Minds.
A small pilot study found associations between specific microbe species and infants' performance in tests of social attention and rhythmic processing. The researchers observed higher levels of Actinobacteria and Bifidobacterium microbes in infants with better cognitive abilities.
Researchers created comprehensive fine-grained functional maps of infant brain networks, providing unprecedented details on brain development from birth to two years old. The study revealed novel insights into when different brain functions develop during infancy and provided valuable references for early brain developmental studies.
A study of 463 infants aged 8-36 months found that those with smaller vocabularies and poorer cognitive skills nap more frequently. Reducing naps for these children may not improve brain development, suggesting a need to re-evaluate sleep recommendations.
Researchers discovered lactate's role in helping neural stem cells develop into specialized neurons. Lactate sends signals to cells, modifying and strengthening neuronal functions. The study provides insight into lactate signaling in the nervous system, with potential applications for preventing or controlling cognitive diseases.
Children who begin reading for pleasure early in life tend to perform better at cognitive tests and have better mental health when they enter adolescence. Reading for pleasure is also associated with improved brain structure, which may help explain the findings.
Researchers used a stem cell model to study the effects of Alzheimer's disease-associated mutations on early human brain development, finding that mutant spheres were larger and contained fewer mature neurons. The study highlights the need for tailored therapies and paves the way for studying Alzheimer's in its early stages.
Research from Keck School of Medicine of USC found that everyday air pollution can alter brain development patterns in adolescents, linked to changes in brain connectivity over time. Exposure to fine particulate matter and nitrogen dioxide was associated with increased or decreased functional connectivity between brain regions.
Research by Fiona Baker of SRI's Human Sleep Lab highlights the deep connections between adolescent sleep and overall health. Studies have shown that poor sleep patterns can affect brain development, weight gain, cognitive decline, and socioemotional difficulties in adolescents.
The study reveals that spontaneous waves of neurotransmitter glutamate facilitate dendrite pruning, while a unique protection/punishment machinery strengthens certain connections and eliminates others. Proper pruning is critical for neural development, with insufficient or excessive connections linked to neurophysiological disorders.
A team of researchers used MRI and audio recordings to demonstrate the association between caregiver speech and infant brain development. Infants who heard more words had slower-developing white matter, but eventually showed better linguistic performance when they began to talk.
Adolescent neurostimulation of dopamine circuitry may reverse genetic deficits in frontal cortex function, rescuing structural and behavioral deficits caused by disorders. Researchers identified critical windows in brain development where interventions can target and change the course of diseases.
A national study published in Sleep Health found that screen habits linked to better sleep include keeping devices out of the bedroom and avoiding screens before bedtime. The study analyzed data from 10,280 preteens aged 10-14 and found that 15.5% reported trouble falling or staying asleep in the past two weeks.
Researchers discovered that marsupial brains exhibit region-specific patterns of cortical activity during early development. This finding provides valuable information about human brain development and may inform strategies for improving cognitive function in humans.
Scientists have developed a new method to genetically modify brain organoids, allowing for quick and effective analysis of gene function in early stages of brain development. This breakthrough enables comparative studies across primate species and simulates neurological diseases without animal experiments.
Research supported by NIDA found that states with stronger social safety nets have lower socioeconomic disparities in brain development and mental health of children. Anti-poverty programs, such as cash assistance and Medicaid expansion, reduce these disparities.
A NYU Abu Dhabi study reveals that improvements in visual functions are linked to changes in white matter pathways and specific brain regions. The research confirms the potential of cataract surgery to improve visual function and brain plasticity, especially when performed at a younger age.
A UToledo-led study found early exposure to pyrethroids may increase the risk of autism and developmental disorders in mice. The researchers discovered behavioral changes, including hyperactivity and repetitive behaviors, which are similar to symptoms seen in human patients with neurodevelopmental disorders.
A new study reveals an association between poor air quality in India and impaired cognition in infants under two. The study found that air quality was poorer in homes that used solid cooking materials like cow dung cake, and that reducing cooking emissions could have benefits to infants' emerging cognitive abilities.
Research suggests that problems with the brain's ability to 'prune' itself of unnecessary connections may underlie a wide range of mental health disorders that begin during adolescence. Adolescents experiencing mental health problems showed similar patterns of brain activity, which were largely apparent in the frontal lobes.
A recent study found a significant rise in cannabis exposures in suspected suicide attempts, with the majority involving other substances. The data highlights the need for increased mental health services and awareness about the risks of cannabis use, particularly among youth.
A recent study published in eClinicalMedicine found that eating walnuts on a regular basis can improve attention functions, fluid intelligence, and behavior in adolescents with ADHD. The research, led by the IISPV, suggests that following a healthy diet is crucial for cognitive development during adolescence.
A recent study published in JAMA Psychiatry found that individuals with a family history of depression exhibit reduced cognitive abilities. The research highlights the potential impact of genetic and environmental factors on brain development and aging, as well as modifiable lifestyle factors.
A Penn Medicine study identified a developmental sequence in brain maturation during adolescence, revealing regions supporting cognitive and social functions remain malleable until late adolescence. The study found that socioeconomic environments have a significant impact on brain development in these regions.
Researchers studied 407 infants born to mothers with mild or asymptomatic COVID-19 at any point during pregnancy and found they developed similarly to those without COVID. The study used a novel method to observe babies remotely, adapting a developmental assessment tool for COVID-safe evaluation.
A Marshall University researcher has received a $388,500 NIH grant to study the effects of binge drinking on brain development and its long-term cognitive consequences. The two-year grant will allow her team to identify mechanisms that drive changes in brain function and explore novel targets for prevention and treatment.
A new study found that LGB preteens ages 10-14 reported 10.4 hours of daily recreational screen time, which was nearly four hours more than their straight peers. The researchers argue that parents should regularly talk to their children about screen usage and develop a family media use plan.
Researchers found that a group of amino acids influence brain development, leading to severe effects after birth if nerve cells are starved. The study showed that mice with low levels of essential amino acids developed microcephaly and exhibited long-term behavioral abnormalities similar to those in autism spectrum disorders.
Researchers at UMass Amherst have discovered that beneficial microbes in infant gut use nitrogen from human milk to support pediatric nutrition and development. The study provides new insights into the molecular underpinnings of these processes, which could lead to improved infant health around the world.
A new national study finds that lesbian, gay, and bisexual (LGB) youth are twice as likely to report trouble falling or staying asleep than their straight peers. This is attributed to greater depression, stress, and family conflict among LGB youth, which can make it harder for them to get a good night's sleep.
The study found sex differences in brain structure and developmental changes in white matter during early childhood. In 5-year-olds, the pattern of white matter asymmetry resembled adult-like patterns, suggesting a possible transient feature in brain development.