Articles tagged with Brain Development
A recent study published in JAMA Psychiatry found that individuals with a family history of depression exhibit reduced cognitive abilities. The research highlights the potential impact of genetic and environmental factors on brain development and aging, as well as modifiable lifestyle factors.
A Penn Medicine study identified a developmental sequence in brain maturation during adolescence, revealing regions supporting cognitive and social functions remain malleable until late adolescence. The study found that socioeconomic environments have a significant impact on brain development in these regions.
Researchers studied 407 infants born to mothers with mild or asymptomatic COVID-19 at any point during pregnancy and found they developed similarly to those without COVID. The study used a novel method to observe babies remotely, adapting a developmental assessment tool for COVID-safe evaluation.
A Marshall University researcher has received a $388,500 NIH grant to study the effects of binge drinking on brain development and its long-term cognitive consequences. The two-year grant will allow her team to identify mechanisms that drive changes in brain function and explore novel targets for prevention and treatment.
A new study found that LGB preteens ages 10-14 reported 10.4 hours of daily recreational screen time, which was nearly four hours more than their straight peers. The researchers argue that parents should regularly talk to their children about screen usage and develop a family media use plan.
Researchers found that a group of amino acids influence brain development, leading to severe effects after birth if nerve cells are starved. The study showed that mice with low levels of essential amino acids developed microcephaly and exhibited long-term behavioral abnormalities similar to those in autism spectrum disorders.
Researchers at UMass Amherst have discovered that beneficial microbes in infant gut use nitrogen from human milk to support pediatric nutrition and development. The study provides new insights into the molecular underpinnings of these processes, which could lead to improved infant health around the world.
A new national study finds that lesbian, gay, and bisexual (LGB) youth are twice as likely to report trouble falling or staying asleep than their straight peers. This is attributed to greater depression, stress, and family conflict among LGB youth, which can make it harder for them to get a good night's sleep.
The study found sex differences in brain structure and developmental changes in white matter during early childhood. In 5-year-olds, the pattern of white matter asymmetry resembled adult-like patterns, suggesting a possible transient feature in brain development.
A study of 11,633 children aged 9-11 found that increased screen time was associated with a higher risk of developing suicidal behaviors two years later. Each additional hour of screen time led to a 9% higher risk of reporting suicidal behavior.
A neuroimaging study of 8,900 children aged 9-11 reveals sex differences in brain connectivity and cognitive performance. The findings suggest that girls mature faster than boys, which may impact future development of brain developmental trajectory charts.
Researchers developed a new imaging technique revealing abnormal circulation patterns of brain fluid in developing brains. Disruptions to cerebrospinal fluid flow may underlie cognitive deficits and developmental delays in conditions like hydrocephalus.
Researchers created monthly infant brain atlases to track normative trends in brain development. The atlases reveal changes in brain structure, cortical geometry, and tissue contrast, shedding light on conditions like ADHD and dyslexia. The study aims to facilitate discovery of new insights into child cognition and social behavior.
New research from Osaka University suggests that spending more time outdoors can reduce the negative effects of screen time on daily living skills in young children. By increasing outdoor playtime, parents may be able to mitigate some of the risks associated with excessive screen time and promote healthier development.
Researchers found that abnormal methylation processes lead to disruption of gene expression essential for brain development in people with Williams syndrome. The study suggests targeting treatments to correct these disruptions.
Researchers found that many changes to human DNA had opposing effects, with some variants making enhancers stronger while others made them weaker. This discovery has implications for understanding human evolution and the potential link between human DNA variations and psychiatric diseases.
Research suggests that social media use in early adolescence may affect the brain's sensitivity to rewards and punishments, potentially influencing psychological adjustment. The study of 169 sixth- and seventh-grade students found associations between habitual checking behaviors on social media and changes in brain development.
A study of 169 students found that habitual social media checking is linked to increased sensitivity in adolescent brains. This increased sensitivity may be an adaptive behavior to navigate the digital world, but also poses potential long-term consequences for brain development.
Research published in Developmental Medicine & Child Neurology reveals a link between maternal diabetes and neurodevelopmental disorders such as autism, ADHD, and intellectual disability in children. Type 1 and type 2 diabetes were associated with increased risks of these conditions, while gestational diabetes was linked to autism spec...
Higher weight and BMI z-scores in pre-adolescence are associated with poor brain health, including structural changes and decreased connectivity. The findings provide an important mechanistic explanation for the link between childhood obesity and impaired cognitive function.
A new MRI study reveals that even low to moderate amounts of alcohol consumption during pregnancy can change the baby's brain structure, leading to delayed brain development. Brain changes were seen in fetuses exposed to alcohol even at low levels, with significant effects on social cognition and language perception.
Researchers found that neonicotinoid chemicals can impair the development of biological motion preference in chicks, similar to autism spectrum disorder in humans. The study suggests that transmission via nicotinic acetylcholine receptors is critical for this process.
Researchers found that higher levels of polybrominated diphenyl ethers (PBDEs) in pregnant women were associated with increased anxiety scores in their children at age 12. The study suggests that exposure to flame retardants during early brain development may be a risk factor for developing anxiety symptoms in early adolescence.
Research reveals early life adversity shapes brain circuits and behavior, increasing risk of depression and anxiety. Studies using rodent models uncover specific neural pathways impacted by early stress, shedding light on sex-specific responses.
Research reveals natural genetic variation impacting brain development contributes to autism's diverse behaviors, with implications for tailored support. The study sheds light on the complex relationships between genetics, brain development, and behavior in individuals with autism.
Researchers generated induced pluripotent stem cells and cerebral organoids from the last male Malaysian Sumatran rhino, enabling study of brain development and potentially aiding in breeding program. The technology holds promise for fighting extinction of critically endangered species.
Researchers found age-related changes in the balance of inhibitory and excitatory neurotransmitters in the prefrontal cortex during adolescence. This study provides first-ever evidence of plasticity in the frontal cortex during this critical developmental period.
Mount Sinai researchers catalogued thousands of sites in the brain where RNA is modified throughout the human lifespan, increasing with age. This study provides a model depicting how A-to-I editing evolves over a lifetime, shedding light on its role in health and disease.
A large study of over 5,800 tween children found that growing up in a socioeconomically disadvantaged household can have lasting effects on brain development, with different patterns of connections between brain regions observed. Parental education emerged as the most significant factor associated with variations in brain connections.
A new study found that gestational exposure to the flame retardant FM 550 resulted in altered brain development in newborn rats, with effects more pronounced in male offspring. The study also showed evidence of mitochondrial disruption and dysregulated choline and triglyceride levels in brain tissue.
A new theory by UMass Amherst sleep scientist Rebecca Spencer suggests that young children's brain development, not age, determines when and why they stop napping. The hippocampus, a memory area of the brain, plays a critical role in nap transitions.
A study has identified a protein complex, Unc5-GPC3, that regulates the migration of neurons and neuroblastoma cancer cells. The complex facilitates the migration of neurons on fibres during brain development and is also present in certain brain tumours.
A study of 332 adolescents found that higher levels of DHA were associated with better selective and sustained attention, while ALA was linked to lower impulsivity. The results suggest the importance of a diet rich in omega-3 fatty acids for healthy brain development.
A prospective multicenter case-control study found that third-trimester fetuses exposed to opioids in utero exhibited smaller brain biometric measurements and altered fetal physiology. The study suggests a possible link between prenatal opioid exposure and postnatal clinical outcomes.
A recent study published in Science Translational Medicine has found that supporting emotional connections between mothers and their premature infants can significantly improve brain development in these babies. The researchers measured the brain network functions of premature infants at term age after receiving either standard care or...
Research reveals that oligodendrocyte precursor cells (OPCs) contribute to the pruning process, helping shape a healthy brain during early development. OPCs actively engulf synapses, eliminating connections that are no longer needed, and play an intermediary role between external experiences and brain activity.
Researchers found molecular mechanisms of brain development during early life influence obesity risk, with epigenetic maturation playing a key role. The study suggests prevention efforts targeting developmental processes could help stop the worldwide obesity epidemic.
Researchers at UCLA and UCSF will map gene regulatory regions to understand how genetic variants affect brain development. They aim to build a comprehensive catalog of cell types in the developing brain and identify specific cell types and genomic regions that mediate the risk of brain diseases.
The study proposes a model to understand the complications caused by zika virus infection during pregnancy. The researchers found that zika virus alters protein expression in neural cells, affecting energy production and RNA metabolism, which can lead to defective myelination and microcephaly.
Researchers at the University of Rochester Medical Center found that children who experience a mild traumatic brain injury are more likely to develop emotional and behavioral problems. The study, which analyzed data from thousands of children, revealed a 15-percent increased risk of these problems in kids with a mild TBI.
Researchers found that modern human brains produce more neurons than Neandertal brains, particularly in the frontal lobe, due to a single amino acid substitution in the TKTL1 protein. This increase is attributed to changes in metabolism and membrane lipid synthesis.
Researchers at the University of California, Irvine have discovered a link between Piezo1 and cholesterol levels during brain development, which may provide new avenues for treating diseases like Alzheimer's. The study found that Piezo1 influences cellular cholesterol metabolism, modulating cell quantity, quality, and organization.
Researchers identified critical period plasticity in the amygdala that can be treated with therapeutic intervention at key developmental time points. Early pharmacological intervention was shown effective in reducing fear-learning in the mouse model.
A study published in Nature Communications suggests that better glucose control can improve brain structure and function in youth with Type 1 diabetes. The findings indicate that participants using a hybrid closed-loop insulin delivery system showed significant improvement in key brain metrics compared to those receiving standard care.
Researchers mapped brain cortex development from two months before birth to two years after, revealing functional regions and growth rates. The study provides a valuable resource for further research on brain development conditions.
A study by researchers at Keck School of Medicine found that flavored oral nicotine products, such as gum and gummies, are increasingly popular among US teens, with 3.4% having used them at least once and 1.7% in the past six months. The use of these products was more common among Hispanic teens, teen girls, and LGBTQ+ teens.
A study of 2,700 children in the Netherlands found a possible association between maternal smoking and suboptimal brain development among offspring. The research suggests that tobacco use during pregnancy may impact preadolescent brain development.
Researchers at MPI-CBG found that modern human variants cause longer metaphase and fewer chromosome segregation errors in neural stem cells, leading to more efficient brain development. This suggests that some aspects of modern human brain evolution may be independent of brain size.
New research from Thomas Jefferson University shows that early childhood enrichment can reverse the effects of lead poisoning on brain development. Over 3,500 genes in the hippocampus are affected by lead exposure, but approximately 80% of gene expression changes are reversed in animals living in stimulating environments.
A recent study published in the New England Journal of Medicine found that adding erythropoietin to cooling therapy for term newborns with birth asphyxia showed no added benefits compared to cooling therapy alone. In fact, the erythropoietin group had more serious adverse events during the newborn period.
A new study led by the University of Washington strengthens evidence that air pollution can harm childhood behavioral problems and IQ. Researchers found prenatal and postnatal exposure to nitrogen dioxide and small-particle air pollution were associated with poorer child behavioral functioning and cognitive performance.
Research finds that preschoolers' brain maturation improves inhibitory control abilities, with 4-year-olds outperforming 3-year-olds in tasks requiring stopping actions. The cognitive control network's distinct regions and white matter connections are associated with different aspects of self-control development.
Researchers found that socially isolated bumblebees exhibited an increase in affiliative behavior, unlike expected aggression. The brain development of isolated bees showed similarities with group-reared bees, suggesting controlled chaos in the absence of social environment.
Indiana University researchers are using a mouse model to study the effects of cannabis use during adolescence, which could impair working memory and increase the risk of psychosis later in life. The $2M NIH grant aims to develop therapies to treat adverse effects.
A new study reveals that up to 10% of pre-teen children are curious about using substances, with boys more likely than girls to be interested. Parents' rules and home access play a significant role in shaping their children's curiosity, with Black parents being more likely to set rules against substance use.
Duke researchers identify DDX3X gene as crucial for neuron formation and brain development, with dosage-dependent defects leading to developmental disabilities. The study sheds light on the molecular mechanisms underlying DDX3X syndrome and related disorders, potentially paving the way for therapies.
A new genetic disease has been identified that causes abnormal brain development in children, resulting in severe learning difficulties. Researchers have discovered the underlying cause of the condition by analyzing changes in a protein coding gene called GRIA1, which helps move electrical signals around the brain.
Studies by UC Davis MIND Institute found predictive protein patterns in expecting mothers' blood and links between maternal autoantibodies and higher autistic traits. MAR ASD patterns were associated with autism before birth, with certain patterns predicting autism in previously diagnosed children.
A new study reveals that using portable HEPA filter air cleaners during pregnancy can improve cognitive development in children. The UGAAR randomized controlled trial found that children born to mothers with air cleaner use had higher intelligence quotients and verbal comprehension scores, indicating a potential benefit of reducing exp...
A Rutgers study analyzing brain stem cells of autism patients found irregularities in early brain development, supporting the concept that ASD arises from poor control of brain cell proliferation. The study discovered that some patients had NPCs producing too many brain cells while others had underproduced cells.