A new study from Michigan Medicine found that adults with more chronic health conditions are at higher risk of serious financial problems, including late payments, poor credit scores, and bankruptcy. The study analyzed nearly 3 million privately insured adults and found that those with seven or more chronic conditions had three to four...
SourceMichigan Medicine - University of Michigan·JournalJAMA Internal Medicine·TypeData/statistical analysis·DateSep 20, 2022
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A new study finds that using race-free equations for estimating kidney function can minimize racial differences in accrued preemptive waiting time. The research suggests that a specific equation, creatinine-based, reduces racial disparities more effectively than another equation, cystatin C-based.
SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateSep 19, 2022
Researchers found that using race-free creatinine formula helps equalize access for Black and white patients. The study showed that among 350 Black patients, kidney failure was reached at an average 23 months, versus an average 22 months for 122 white patients.
SourceUniversity of California - San Francisco·JournalClinical Journal of the American Society of Nephrology·DateSep 19, 2022
For seven years after bariatric surgery, participants showed clinically important improvements in pain levels, physical function, and work productivity, with some backsliding over time. The study found durable effects on walking speed, fitness, and most metrics of pain, even among older adults.
SourceUniversity of Pittsburgh·JournalJAMA Network Open·DateSep 14, 2022
The study found a significant decline in peritoneal dialysis-associated peritonitis rates over time, with consistent differences in risk by race and age. The decline suggests improvements in clinical practice and highlights the importance of uniform coding standards to identify additional risk factors.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateSep 13, 2022
A study from Linköping University shows that individuals with type 1 diabetes should keep their mean long-term sugar level below 53 mmol/mol (7.0%) to avoid serious damage. The risk of eye- and kidney complications increases as the level increases.
SourceLinköping University·JournalDiabetes Care·TypeObservational study·DateSep 12, 2022
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A prespecified subgroup analysis of East Asian adults with lupus nephritis found that belimumab added to standard therapy improved kidney outcomes significantly. The study also showed no new safety concerns were raised in the subgroup.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateSep 2, 2022
Researchers at Washington University have developed a hydrogel system that preserves biochemistry and mechanical environments of cultured podocyte cells. This allows researchers to identify new ways to control mechanisms used by cells to heal themselves, potentially leading to therapies for currently incurable diseases.
SourceWashington University in St. Louis·JournalScience Advances·TypeExperimental study·DateAug 31, 2022
Researchers have developed a new labeling technique to analyze exosomes from specific cell types, providing insights into their role in both health and disease. The technique allows for the identification of protein cargo and RNA in exosomes, enabling the study of cellular communication and potential monitoring of response to treatment.
SourceMedical College of Georgia at Augusta University·JournalJournal of Extracellular Vesicles·DateAug 30, 2022
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers at Brigham and Women's Hospital have developed a highly efficient method to generate human kidney cells, including principal and intercalated cell lines. This breakthrough could lead to new therapies for treating congenital abnormalities of the kidney and urinary tract, such as polycystic kidney disease.
SourceBrigham and Women's Hospital·JournalNature Biotechnology·TypeExperimental study·DateAug 30, 2022
A new study found that kidney transplant recipients experience immune insufficiency during acute COVID-19, despite reduced immunosuppression. This phenomenon is associated with increased expression of innate immune pathways and decreased activation of adaptive immune pathways.
SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateAug 30, 2022
A new study from Aarhus University found that lysine, an amino acid supplement, protects laboratory animals from kidney damage and prevents hypertensive kidney disease. The research suggests that a diet rich in lysine may help prevent or treat kidney diseases, but more studies are needed to confirm the results.
SourceAarhus University·JournalNature Communications·TypeExperimental study·DateAug 19, 2022
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A recent study suggests that many patients on the transplant waitlist would accept lower quality kidneys in exchange for a shorter waiting time. The research identifies three patient-preference classes, with some respondents willing to accept increases in waiting time for small improvements in kidney quality.
SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateAug 19, 2022
A new study found that peritoneal dialysis (PD) costs Medicare less than hemodialysis, even as more patients are placed on PD. The analysis of US Medicare beneficiaries showed that overall average expenditures were 11% higher for hemodialysis than for PD.
SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateAug 18, 2022
Researchers identified differences in PTK activity between normal and cancer kidney tissue, with Src family kinases and PI3K pathways exhibiting high activity. Ex vivo treatment of clear cell RCC with TKIs revealed that tivozanib and cabozantinib were more potent inhibitors than sunitinib or pazopanib.
SourceImpact Journals LLC·JournalOncotarget·TypeData/statistical analysis·DateAug 17, 2022
A quality improvement program increased pneumococcal vaccination rates from 53% to 70% in adults aged 18-64 years with stage 4 and 5 chronic kidney disease. The intervention, which utilized electronic best practice alerts within the electronic medical record, improved vaccination rates primarily among this high-risk group.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateAug 17, 2022
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Researchers have discovered a molecule that can suppress the development of kidney fibrosis, a condition leading to kidney failure and devastating consequences. The breakthrough could lead to the development of new drug treatments for millions of people affected by chronic kidney disease.
SourceVirginia Tech·JournalScience Translational Medicine·DateAug 17, 2022
Women tend to have lower kidney function than men in middle age, but their kidney function declines more slowly over time. This study provides important knowledge regarding age-related loss of kidney function and sex disparities in the prevalence of CKD.
SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateAug 17, 2022
Researchers discovered a rare genetic mutation that may lead to better diabetes treatments for patients, regardless of whether they inherited the mutation. The study found that carriers of the mutation had lower levels of adiponectin and higher levels of ceramides in their blood.
SourceUniversity of Utah Health·Journalnpj Genomic Medicine·TypeExperimental study·DateAug 16, 2022
A new study published in Pediatric Transplantation found that pediatric kidney transplant patients have better long-term outcomes when their kidney comes from a living donor. The study analyzed data from the Organ Procurement and Transplant Network database and compared the rates of graft failure and death among children who received k...
SourceUniversity of California - Davis Health·JournalPediatric Transplantation·TypeData/statistical analysis·DateAug 15, 2022
Scientists aim to improve vein health for patients undergoing heart bypass surgery and dialysis. They discovered that two genes play a crucial role in smooth muscle cell differentiation, enabling veins to mature and function like arteries.
SourceMedical College of Georgia at Augusta University·DateAug 11, 2022
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Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Higher aldosterone concentrations are associated with lower eGFR, lower potassium levels in blood, and higher potassium and protein concentrations in urine. The risk of CKD worsening was independent of diabetes status. Finerenone may help prevent CKD progression by targeting aldosterone's action.
SourceEuropean Society of Cardiology·JournalEuropean Heart Journal·TypeObservational study·DateAug 8, 2022
A 12-month exercise program improved physical functioning and aerobic exercise capacity in adults with CKD stages G3b-4. The program, which included resistance and aerobic exercise, showed no significant impact on cardiovascular risk factors.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·TypeRandomized controlled/clinical trial·DateAug 8, 2022
Researchers identified lipopolysaccharide-responsive and beige-like anchor protein (LRBA) as a crucial regulator of aquaporin-2 water channels in the kidneys. The study found that LRBA interacts with PKA to facilitate AQP2 activation, maintaining water homeostasis and preventing polyuria.
SourceTokyo Medical and Dental University·JournalProceedings of the National Academy of Sciences·DateAug 4, 2022
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
A new USC analysis found that the largest Medicare Advantage plans pay 27% more for outpatient dialysis treatment compared to traditional Medicare. This significant markup is attributed to the consolidation of the dialysis industry, with two large chains supplying over three-quarters of all dialysis services in the US.
SourceKeck School of Medicine of USC·JournalHealth Affairs·TypeData/statistical analysis·DateAug 2, 2022
A Mayo Clinic study found that diets rich in calcium and potassium can help prevent recurrent symptomatic kidney stones. Patients who experienced a first-time stone were more likely to experience recurrence if their diet was low in these nutrients.
SourceMayo Clinic·JournalMayo Clinic Proceedings·DateAug 1, 2022
Women are less likely to receive diagnostic codes related to CKD, be referred to a nephrologist, and have their kidney function monitored compared to men. Despite guidelines recommending equal care, women receive suboptimal management of chronic kidney disease, with lower rates of testing and guideline-recommended medications.
SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateJul 29, 2022
Adults with chronic kidney disease are more likely to have a low intake of fruits and vegetables compared to similar individuals without the condition. This study suggests that increasing fruit and vegetable consumption may be beneficial for overall health.
SourceUniversity of Virginia Health System·JournalJournal of Renal Nutrition·TypeData/statistical analysis·DateJul 26, 2022
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Pediatric kidney transplant recipients with high tacrolimus intrapatient variability are at increased risk of developing antibodies against the transplanted kidney. This variability can be identified through hospital electronic health records, allowing for early intervention to prevent rejection and improve graft outcomes.
SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateJul 26, 2022
A qualitative study highlights the importance of timely and balanced information exchange in shared decision-making for vascular access placement. This collaborative approach involves presenting choices, sharing personalized knowledge, and eliciting patients' values and preferences to strengthen treatment plans.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateJul 20, 2022
A new analysis led by University of Pittsburgh School of Public Health epidemiologists found that adults who undergo bariatric surgery are more than twice as likely to get married within five years. Conversely, married patients who receive bariatric surgery are more than twice as likely to get divorced.
SourceUniversity of Pittsburgh·JournalAnnals of Surgery Open·DateJul 20, 2022
Researchers analyzed electronic health records and found rosuvastatin associated with higher risks of hematuria, proteinuria, and kidney failure. High-dose rosuvastatin poses additional risk, especially for patients with advanced kidney disease.
SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateJul 19, 2022
Studies in rats have found that T-cells produce reactive oxygen species (ROS) that contribute to preeclampsia complications. Researchers are exploring ways to dampen this response to reduce the risk of premature birth or worse outcomes for mother and child.
SourceMedical College of Georgia at Augusta University·DateJul 19, 2022
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A new clinical model predicts hospital mortality and major adverse kidney events in critically ill patients with acute kidney injury. The proposed model exhibits good performance for outcome prediction, enabling timely interventions to promote kidney recovery.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateJul 19, 2022
Researchers at the University of South Australia have discovered that combining anti-rejection medication with immune checkpoint inhibitors can significantly reduce the risk of organ rejection and eliminate cancer cells in a quarter of patients. The study involved 22 patients with renal transplants and incurable locally advanced or met...
SourceUniversity of South Australia·JournalThe Lancet Oncology·TypeExperimental study·DateJul 18, 2022
Lumasiran, an RNA interference therapeutic, has been shown to reduce oxalate levels in patients with primary hyperoxaluria type 1 (PH1) who have relatively preserved kidney function. In the ILLUMINATE-C study, lumasiran resulted in substantial reductions in plasma oxalate with acceptable safety in patients on hemodialysis.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateJul 14, 2022
A study found that widely-used kidney function tests are inaccurate for predicting kidney disease in African populations, suggesting a significant underestimation of kidney disease prevalence. The creatinine-based test was shown to be less effective due to unique biological characteristics in African populations, while the cystatin C t...
SourceUniversity of the Witwatersrand·JournalThe Lancet Global Health·TypeExperimental study·DateJul 13, 2022
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A study published in The American Journal of Medicine found that regular physical activity can substantially reduce the risk of chronic kidney disease in individuals from lower socioeconomic backgrounds. Participants with higher levels of fitness showed a significantly lower risk of developing the disease, even among those with low soc...
SourceUniversity of Bristol·JournalThe American Journal of Medicine·TypeObservational study·DateJul 12, 2022
A recent study published in JASN uncovers a previously overlooked mechanism contributing to ADPKD, suggesting that the loss of polycystin-2 protein in the endoplasmic reticulum plays a crucial role. Activating TricB may be a promising treatment strategy for ADPKD.
SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateJul 12, 2022
Research suggests that paternal genetic factors play a role in susceptibility to preeclampsia, but the impact of paternal phenotype and lifestyle remains unclear. The study found no significant differences in socioeconomic background or health history between fathers with preeclamptic pregnancies and those without.
SourceWiley·JournalActa Obstetricia Et Gynecologica Scandinavica·DateJul 7, 2022
Researchers generated simple kidney-like structures called organoids and used them to identify potential drugs for adult-onset polycystic kidney disease. They found nine compounds that inhibited cyst growth without stunting overall growth.
SourceKeck School of Medicine of USC·JournalCell Stem Cell·TypeExperimental study·DateJul 7, 2022
A study found that rates of serious complications associated with shoulder surgery are low, but one in 26 patients need further surgery within a year. The effectiveness of some shoulder procedures is doubtful at best, according to experts.
SourceBMJ Group·TypeObservational study·DateJul 6, 2022
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Researchers have discovered that Schwann Cell Precursors are the origin of tuberous sclerosis complex tumours in the kidney. Lab-grown 'mini-kidneys' were used to create a genetic profile similar to TSC tumours, revealing the diversity in tumour size and cellular makeup within patients.
SourceThe Ottawa Hospital·JournalCell Reports·TypeExperimental study·DateJul 6, 2022
A case report highlights the dangers of excessive vitamin D intake, with symptoms including abdominal pain, leg cramps, and kidney abnormalities. Doctors warn that hypervitaminosis D is on the rise and can lead to serious health problems if not taken safely.
SourceBMJ Group·JournalBMJ Case Reports·TypeObservational study·DateJul 5, 2022
A cross-sectional study found significant differences between estimated glomerular filtration rate (eGFR) and directly measured GFR (mGFR), highlighting the importance of considering uncertainty in eGFR calculations. Researchers suggest renaming eGFR as a population average GFR to improve accuracy.
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeObservational study·DateJul 4, 2022
Researchers at Kyoto University discovered a unique subpopulation of resident fibroblasts that produce erythropoietin, a hormone critical for oxygen delivery in the kidneys. This 'crack team' of kidney cells has been found to play a crucial role in disease recovery and may hold new avenues for treatment.
SourceKyoto University·JournalKidney International·TypeExperimental study·DateJun 30, 2022
Researchers found that factory-calibrated continuous glucose monitors are sufficiently accurate for estimating blood-sugar levels in patients with end-stage renal disease on hemodialysis. The devices showed 'clinical reliability', with almost 99% of readings accurate enough to be used without confirmatory fingerstick blood sugar readings.
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A new study published in JAMA Network Open found that patients who received lactated Ringer solution instead of normal saline for IV fluids had a lower risk of kidney injury and death. The study, which included nearly 150,000 hospital patients, showed a 2.2% reduced risk of major adverse kidney events.
SourceIntermountain Healthcare·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateJun 29, 2022
A new study from Karolinska Institutet has identified a key mechanism behind treatment resistance in a deadly form of kidney cancer. By increasing mitochondrial content in cancer cells, researchers found that these cells became susceptible to the cancer drug sorafenib. This breakthrough offers hope for more targeted cancer treatments.
SourceKarolinska Institutet·JournalNature Metabolism·DateJun 27, 2022
A study found that over 60% of parents of children with kidney disease or hypertension are unsure or unwilling to vaccinate their child against COVID-19. Effective vaccines exist to protect children from COVID-19, and the findings highlight the need for clear communication to address parental concerns.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateJun 21, 2022
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers found that invasive therapy for non-ST segment elevation myocardial infarction in patients with CKD is associated with lower mortality and reduced risk of cardiac events. The study challenges the dominant practice of offering medical management instead of invasive therapy for this population.
SourceIndiana University School of Medicine·JournalJournal of the American Heart Association·DateJun 21, 2022
Chronic kidney disease and glaucoma have been found to share common risk factors such as diabetes and hypertension, leading to a higher risk of developing both conditions. The study also reveals that patients with glaucoma are more likely to develop chronic kidney disease over time.
SourceNational University of Singapore, Yong Loo Lin School of Medicine·JournalEClinicalMedicine·TypeMeta-analysis·DateJun 21, 2022
A recent review article highlights the crucial role of macrophages in the progression from acute kidney injury (AKI) to chronic kidney disease (CKD). The study suggests that targeting specific signaling pathways and altering macrophage activation can prevent renal fibrosis and CKD. Therapeutic strategies such as clodronate liposomes an...
SourceCactus Communications·JournalChinese Medical Journal·TypeLiterature review·DateJun 20, 2022
A new algorithm can analyze thousands of genomic variants to estimate a person's risk of developing chronic kidney disease, with the highest scores indicating tripled risk compared to the general population. Early detection may prevent many cases of kidney failure and reduce the need for transplant or dialysis.
SourceColumbia University Irving Medical Center·JournalNature Medicine·TypeData/statistical analysis·DateJun 16, 2022
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Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A study found that US adults receiving hemodialysis with high air pollution exposure have more heart attacks and strokes compared to those with low exposure. The strongest associations were noted among patients who were Asian, older, or had chronic lung disease at dialysis initiation.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateJun 14, 2022
A third dose of COVID-19 vaccine may be essential for kidney transplant patients in Japan to prevent severe disease and infection. Researchers found that only a third of patients developed sufficient antibodies after two doses, highlighting the need for additional protection.
SourceNagoya University·JournalScientific Reports·DateJun 5, 2022
A recent study published in Kidney International Reports reveals that consuming at least one cup of coffee per day may reduce the risk of acute kidney injury (AKI) by 15%. The largest reductions were observed in individuals who drank two to three cups of coffee daily, with a 22% lower risk.
SourceJohns Hopkins Medicine·JournalKidney International Reports·DateJun 2, 2022
Researchers at the University of Houston have identified blood biomarkers predicting heart disease in lupus patients and urine biomarkers for diagnosing kidney inflammation in children with lupus. These findings hold promise for early preventive measures and improved treatment outcomes.
SourceUniversity of Houston·JournalFrontiers in Cardiovascular Medicine·DateJun 2, 2022
A University of Queensland-led study found that millions of COVID-19 patients may have undiagnosed acute kidney injury (AKI), which can lead to serious illness or death. The true AKI diagnosis rates are likely double existing data, highlighting the need for improved detection and management strategies.
SourceUniversity of Queensland·JournalPLOS Medicine·TypeObservational study·DateJun 2, 2022
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Patients with primary glomerular diseases have a significantly higher risk of cardiovascular events, including coronary artery disease and stroke. The study found that inclusion of kidney-specific risk factors improved the prediction of cardiovascular events.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateJun 1, 2022