Scientists have discovered that certain metals found in people's urine could be potentially useful clinical biomarkers for the early detection of acute kidney injury (AKI). The study, which was led by experts from the University of Nottingham, found that concentrations of these metals rose in urine within an hour after cardiac surgery ...
SourceUniversity of Nottingham·JournalKidney International Reports·TypeExperimental study·DateMay 30, 2022
Researchers at Kyoto University identify a distinct subpopulation of fibroblasts responsible for producing the hormone erythropoietin (Epo), which stimulates red blood cell production. This discovery provides insight into renal anemia and may lead to novel treatment methods for patients with chronic kidney disease.
SourceKyoto University·JournalKidney International·TypeExperimental study·DateMay 27, 2022
A recent study published in CJASN found that SGLT-2 inhibitors were not associated with an increased risk of fractures in adults with chronic kidney disease, regardless of their kidney function. The study included over 38,000 new users of the medications and compared them to those prescribed a different diabetes medication.
SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateMay 26, 2022
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
A study found that patients with IgD multiple myeloma have a worse prognosis than other types, with higher mortality rates and more kidney damage. The rare blood cancer produces excessive light chains that can damage the kidneys if left untreated.
SourceMedical College of Georgia at Augusta University·JournalInternational Journal of Pathology and Clinical Research·DateMay 19, 2022
A protocol-based potassium supplementation strategy resulted in a longer time to the first peritonitis episode and a lower hazard ratio of peritonitis compared to reactive supplementation. This approach also improved PD-related outcomes by significantly reducing the risk of peritonitis.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateMay 18, 2022
A large randomized controlled trial found that treatment with methylprednisolone reduces the risk of kidney function loss and failure in patients with IgA nephropathy. The study's results suggest a lower dose regimen may be effective while minimizing side effects.
SourceGeorge Institute for Global Health·JournalJAMA·TypeRandomized controlled/clinical trial·DateMay 17, 2022
Researchers created human mini-kidneys that mimic diabetic kidneys, finding increased susceptibility to SARS-CoV-2 infection and a critical role for the ACE2 receptor. The study provides new insights into the link between diabetes and COVID-19 disease.
SourceInstitute for Bioengineering of Catalonia (IBEC)·JournalCell Metabolism·TypeExperimental study·DateMay 12, 2022
A large study has found six predictors that can help determine the optimal lithium dose for patients with bipolar disorder. The predictors include age, sex, kidney function, and medication use. The researchers hope to develop a digital app to aid psychiatrists in finding the right dose.
SourceKarolinska Institutet·JournalThe Lancet Psychiatry·DateMay 12, 2022
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A qualitative study of Black veterans with chronic kidney disease reveals feelings of anger and resentment towards racist encounters in healthcare. Participants expressed a strong sense of distrust in the healthcare system, highlighting the need for increased awareness and action to address racism.
SourceJAMA Network·JournalJAMA Network Open·DateMay 12, 2022
Researchers at the University of Waterloo found that combining diuretics and renin-angiotensin system inhibitors with ibuprofen can lead to acute kidney injury in people with certain medical profiles. The combination may be a 'triple whammy' that exacerbates dehydration, which is a major factor in acute kidney injury.
SourceUniversity of Waterloo·JournalMathematical Biosciences·DateMay 5, 2022
Researchers have identified potential biomarkers in lupus nephritis through large-scale protein analysis, which may replace invasive tests. The study's findings could lead to more accurate diagnosis and treatment of the disease.
SourceUniversity of Houston·JournalFrontiers in Immunology·DateMay 4, 2022
State bans on affirmative action policies are associated with lower enrollment of underrepresented minority students in public medical schools. The study found a 5.5 percentage point decrease in enrollment of underrepresented students relative to control schools.
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeData/statistical analysis·DateMay 2, 2022
A new study by the Mayo Clinic confirms that living kidney donor surgery via laparoscopic surgery is low-risk for most patients, with only 2.5% experiencing major complications. The study tracked over 3,000 donors and found that most complications occurred after discharge.
SourceMayo Clinic·JournalMayo Clinic Proceedings·DateApr 25, 2022
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
A team of researchers has identified two transcription factors, AP-2α and AP-2β, that regulate distinct segments of the distal nephron in the mammalian kidney. The study sheds light on the molecular mechanisms underlying urinary concentration and its implications for treating kidney diseases.
SourceMassachusetts General Hospital·JournalNature Communications·TypeExperimental study·DateApr 25, 2022
Researchers at Duke University discovered that SARS-CoV-2, the virus causing COVID-19, can directly infect and damage specific types of kidney cells. The virus hijacks the cell's machinery to replicate, leading to structural damage and increased production of viral particles.
SourceDuke University·JournalFrontiers in Cell and Developmental Biology·TypeExperimental study·DateApr 21, 2022
A new study found that Black kidney transplant recipients exhibit a faster clearance rate of tacrolimus, an immunosuppressive drug. The study suggests that considering both sex and race when dosing tacrolimus may reduce adverse effects and enhance transplant outcomes.
SourceUniversity at Buffalo·JournalPharmacotherapy The Journal of Human Pharmacology and Drug Therapy·DateApr 18, 2022
Researchers at The University of Toledo found that low-dose lithium acts as a powerful anti-aging agent in the kidneys by blocking GSK3-beta, an enzyme associated with cellular aging. Studies showed improved kidney function and reduced albuminuria in mice and psychiatric patients treated with lithium.
SourceUniversity of Toledo·JournalJournal of Clinical Investigation·TypeExperimental study·DateApr 12, 2022
Patients with mild to moderate kidney disease and kidney transplant recipients had a higher risk of cancer. They also faced a higher risk of dying from cancer, particularly from cancers such as bladder, kidney, and multiple myeloma, compared to those with normal kidney function.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateApr 8, 2022
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A recent analysis found that hospital admissions for children with lupus showed a decrease in severe kidney problems over time. However, racial disparities persist, with Black and Asian children at higher risk of developing new kidney problems.
SourceWiley·JournalArthritis & Rheumatology·DateApr 6, 2022
Researchers found that metal concentrations were particularly elevated in CWSs serving semi-urban, Hispanic communities, highlighting environmental justice concerns. Arsenic, barium, chromium, selenium, and uranium concentrations were also disproportionately elevated.
SourceColumbia University's Mailman School of Public Health·JournalThe Lancet Planetary Health·DateApr 6, 2022
Researchers have discovered a significant association between acute kidney injury and an increased risk of developing dementia in patients hospitalized with AKI. Early detection and monitoring may lead to improved outcomes for this high-risk population.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateApr 4, 2022
A new study used a virtual population to simulate a clinical trial examining kidney damage in Black Americans. The model predicted kidney damage and showed that adding drug therapy and reducing salt intake could stop the damage, improving heart sizes as well.
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
This year's Experimental Biology 2022 meeting features groundbreaking studies on COVID-19 vaccine-associated symptoms in non-menstruating people, a plant compound showing promise for alleviating food allergies, and the potential of omega-3s to boost immunotherapy's cancer-fighting power. Researchers also explore the safety of using CBD...
A new instrument, KART 2.0, measures Chronic Kidney Disease (CKD) and transplant-related knowledge to identify patients who could benefit from additional education and counselling. The tool was validated in a diverse group of patients with moderate to severe CKD.
SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateMar 24, 2022
A post-hoc subgroup analysis of the AFIRE trial found that reduced kidney function significantly influences bleeding events during antithrombotic therapy. Patients with healthy kidney function have a decreased risk of bleeding over time, while those with reduced kidney function remain at high risk.
SourceKumamoto University·JournalBMC Medicine·TypeRandomized controlled/clinical trial·DateMar 24, 2022
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers have successfully used a new sound wave technique called burst wave lithotripsy (BWL) to break up kidney stones in humans, achieving a median of 90% stone volume fragmentation within 10 minutes. The procedure shows potential for an office-based treatment approach with minimal tissue injury and no anesthesia required.
SourceWolters Kluwer Health·JournalThe Journal of Urology·DateMar 22, 2022
A new commentary reveals the underappreciated costs of switching to peritoneal dialysis, which may limit its use in the US. The study identifies policies that could be implemented to address cost-related barriers and increase uptake of peritoneal dialysis.
SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateMar 21, 2022
Researchers at University of Cologne discovered that specific diets can safeguard against acute kidney injury in mouse models. The six tested diets showed overlapping changes in cysteine catabolism as a potential mechanism for organ protection.
SourceUniversity of Cologne·JournalTranslational Research·TypeExperimental study·DateMar 21, 2022
A new study suggests including the 'Deciding Not to Decide' treatment option can improve care for older adults with chronic kidney disease, giving them more time to make informed decisions about their treatment. Researchers argue that this approach strengthens patient-centered care and increases patient autonomy.
SourceRutgers University·JournalJournal of the American Society of Nephrology·TypeObservational study·DateMar 16, 2022
Researchers found that impaired kidney function is preferentially associated with cardioembolic stroke in a large cohort of patients. Low filtration rates and high urine protein levels predicted increased risk of cardioembolic stroke, disability, and mortality.
SourceNational Cerebral and Cardiovascular Center·JournalNeurology·DateMar 14, 2022
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Dialysis facilities referred more incident patients, transplant centers evaluated more, but fewer were placed on the waitlist following KAS implementation. This led to a decline in overall waitlisting nationwide.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateMar 14, 2022
Researchers identified peripheral tissues as source of blood amyloid beta, which regulates blood glucose levels and suppresses insulin secretion. The study suggests a possible mechanism linking type 2 diabetes to Alzheimer's disease development.
SourceOsaka City University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMar 14, 2022
A study at Duke-NUS Medical School found that inhibiting IL-11 can reduce kidney damage, inflammation, and scarring in Alport syndrome mice. Combining this therapy with ACEi treatment increased lifespan by over 400%.
SourceDuke-NUS Medical School·JournalJournal of the American Society of Nephrology·TypeExperimental study·DateMar 9, 2022
Researchers from Osaka University discovered that MondoA protein delays cellular senescence by activating autophagy, promoting longevity. Activation of MondoA also maintains mitochondrial stability, preventing senescence in tissues like the kidney.
SourceOsaka University·JournalCell Reports·TypeNews article·DateMar 7, 2022
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Researchers found that a community-based approach to reporting APOL1 genetic test results resulted in lower blood pressure readings among hypertensive patients. This trial suggests that involving communities in genetic testing could be beneficial for reducing the risks of chronic kidney disease.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateMar 4, 2022
A new dialysis system can produce sterile, medical grade water in the home, providing an affordable option for patients with kidney failure. The Ellen Medical Devices Point-of-Care system has been tested and found suitable for use in peritoneal dialysis fluid production.
Researchers discovered that a specific osmolyte causes kidney cells to undergo an EMT transformation, leading to renal failure. The team found a way to prevent this change by arresting focal adhesion rearrangement, suggesting a new approach to enhance therapeutic value of common osmolytes.
SourceTokyo Metropolitan University·JournalPLOS ONE·DateFeb 26, 2022
A new study found that palliative care for hospitalized patients with both COVID-19 and acute kidney injury (AKI) was often called later than expected, despite the high risk of death. Palliative care supports primary doctors in managing emotional and physical symptoms while assisting in advance care planning.
SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateFeb 24, 2022
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A Brazilian study of 2,777 patients hospitalized between January 5 and September 12, 2021 found that vaccination was the sole predictor of mortality in those over 60 with kidney failure. Vaccination also reduced hospitalization risk among non-vaccinated patients with comorbidities.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalJournal of Infection·DateFeb 24, 2022
Researchers at MDI Biological Laboratory discovered that age-related chronic inflammation is caused by disruption of chromatin architecture. This leads to misexpression of genes lacking CpG islands, resulting in inflammation and loss of cellular function. The findings provide a unifying theory for the age-related degenerative diseases.
SourceMDI Biological Laboratory·JournalScience Advances·TypeData/statistical analysis·DateFeb 22, 2022
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that obesity may increase the risk of end-stage kidney disease in women with type 2 diabetes. Managing blood pressure and sugar levels is not enough to slow progression, emphasizing the need for weight management.
SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology and Metabolism·DateFeb 22, 2022
Young adults are disproportionately excluded from kidney transplantation, with only 1.8% of Black and 4.4% of Hispanic patients receiving the treatment compared to 10.9% of White patients within this age group. The study highlights the need for targeted interventions to address these disparities.
SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateFeb 22, 2022
A recent study led by Dr Simon Fraser from the University of Southampton found that painkiller prescriptions decreased during the pandemic, but high-risk individuals continued to receive them. The research highlights the need for greater caution when prescribing non-steroidal anti-inflammatory drugs (NSAIDs) to prevent kidney damage.
SourceUniversity of Southampton·JournalBJGP Open·TypeMeta-analysis·DateFeb 17, 2022
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
A population-based study found that reducing ambient fine particulate matter (PM2.5) concentration led to significant improvements in laboratory test results for kidney function, including increased glomerular filtration rate and decreased blood urea nitrogen and uric acid levels.
SourceHealth Data Science·JournalHealth Data Science·TypeData/statistical analysis·DateFeb 17, 2022
A new study published in JAMA Internal Medicine has found that gene variants increased the risk of acute kidney injury and death in African American veterans hospitalized with COVID-19. The study, which analyzed data from over 850,000 diverse veterans, identified APOL1 variants as a key contributor to this increased risk.
SourceVanderbilt University Medical Center·JournalJAMA Internal Medicine·TypeData/statistical analysis·DateFeb 10, 2022
A study by Henry Ford Health System found that one in four patients who developed acute kidney injury (AKI) die within a year, emphasizing the urgent need for improved treatments. The study analyzed data from over 1.6 million U.S. Veterans hospitalized between 2008 and 2017, providing valuable insights into AKI-associated mortality.
SourceHenry Ford Health·JournalClinical Journal of the American Society of Nephrology·DateFeb 10, 2022
Researchers created two new prediction tools for patients with CKD, incorporating factors such as long-term blood sugar, inflammation, and kidney/heart injury. The models improve risk classification for stroke and heart attack within 10 years compared to standard models.
SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateFeb 10, 2022
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
Researchers found that 30% of fetuses who later developed ASD had heart, kidney, and head anomalies detected during routine prenatal ultrasounds. These anomalies were more common in girls and linked to the severity of ASD. The study suggests that doctors can use these signs to evaluate the probability of a child being born with ASD.
SourceBen-Gurion University of the Negev·JournalBrain·TypeImaging analysis·DateFeb 9, 2022
Researchers found that current screening protocols for compassionate dialysis are putting too much strain on emergency rooms, leading to longer wait times. The protocols can be adjusted to relieve congestion, but only if implemented effectively.
SourceSouthern Methodist University·JournalIISE Transactions·TypeData/statistical analysis·DateFeb 9, 2022
A large-scale study found that simulation-based surgical training increased surgeons' skills for complex surgeries, with fewer total complications and ureteric injuries. Simulation training led to higher overall proficiency scores and fewer procedures required to achieve proficiency in complex surgeries.
SourceHokkaido University·JournalEuropean Urology·TypeObservational study·DateFeb 8, 2022
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Pulmonary lymphangioleiomyomatosis (LAM) is a rare cancer affecting up to 1 in 1 million women worldwide, characterized by uncontrolled tumor cell growth. Researchers aim to identify new therapeutic targets using extracellular vesicles, with the goal of developing new therapies for LAM patients.
SourceTexas Tech University Health Sciences Center·DateFeb 8, 2022
Researchers studied 23 adults with chronic kidney disease and their caregivers, finding that challenges include burden, responsibility, and power dynamics. The study aimed to develop a practical framework for investigators to involve more patients and caregivers in research.
SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateFeb 7, 2022
A recent study found that patients with acute kidney injury (AKI) face both short- and long-term risks, with over 1 in 4 dying within a year of hospitalization. The study analyzed data from the Veterans Health Administration and identified significant mortality trends associated with AKI.
SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateFeb 7, 2022
A team of researchers at Kumamoto University successfully created complex 3D kidney tissue in the lab using mouse embryonic stem cells. The breakthrough could lead to advances in kidney research and potentially even transplantable organs.
SourceKumamoto University·JournalNature Communications·TypeExperimental study·DateFeb 1, 2022
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A new study aims to improve antibody responses in kidney and liver transplant recipients to COVID-19 mRNA vaccine doses, exploring the impact of reduced immunosuppressive medication. The CPAT-ISR trial will enroll up to 400 adults with a history of organ transplants and evaluate the effectiveness of this strategy.
SourceNIH/National Institute of Allergy and Infectious Diseases·DateJan 31, 2022
Researchers at Johns Hopkins Medicine have successfully transplanted a kidney from a COVID-19 donor, demonstrating that healthy kidneys from such donors can be safely transplanted. The recipient has shown no signs or symptoms of the virus and has excellent kidney function since the transplant.
SourceJohns Hopkins Medicine·JournalAmerican Journal of Transplantation·DateJan 31, 2022
Men and women with advanced kidney disease show differing health-related quality of life trajectories, with women experiencing lower scores initially but a more gradual decline over time. Factors such as kidney function decline, phosphate levels, and hemoglobin also influence physical and mental health scores in both men and women.
SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateJan 24, 2022
UAB surgeons successfully transplanted a genetically modified pig kidney into a brain-dead human recipient, testing safety and feasibility in a novel human preclinical model. The experiment showed that the xenograft perfused normally and maintained vascular integrity, paving the way for potential treatment of thousands with organ failu...
SourceUniversity of Alabama at Birmingham·JournalAmerican Journal of Transplantation·TypeExperimental study·DateJan 20, 2022
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Researchers at UAB successfully transplanted genetically modified pig kidneys into a brain-dead human, demonstrating the feasibility of xenotransplantation. The kidneys functioned for 77 hours without immediate rejection, paving the way for potential treatment of thousands suffering from kidney failure.
SourceUniversity of Alabama at Birmingham·JournalAmerican Journal of Transplantation·TypeExperimental study·DateJan 20, 2022
A high protein diet may harm polar bears, with captive bears showing signs of kidney disease and shorter lifespans. Researchers propose adopting a diet with a fat-protein ratio similar to that found in the wild to improve bear health and longevity.
SourceWashington State University·JournalZoo Biology·TypeLiterature review·DateJan 19, 2022