Articles tagged with Mushrooms
A recent study estimated a significant increase in psilocybin use in Oregon and Colorado following decriminalization. The research suggests a potential shift in user behavior, with more individuals exploring the substance.
A randomized, double-blind clinical trial found that a natural fungal supplement, FoTv, reduced short-term vaccine side effects and helped antibodies last longer in people who had not previously been exposed to COVID-19. The study suggests that FoTv may help strengthen vaccine protection without increasing side effects.
A federally funded research initiative at Oregon Health & Science University examines the safety and effectiveness of state-regulated access to psilocybin, a psychedelic substance used for treating mental health conditions. The five-year study aims to assess the impact of legal psychedelic services on substance use disorders.
Fungi have evolved unique strategies to digest charcoal and other pollutants, including gene duplication and horizontal gene transfer. These discoveries could lead to new methods for cleaning up contaminated environments.
A large-scale population genomic study has shed new light on the evolutionary history of the button mushroom (Agaricus bisporus), one of the most widely cultivated edible fungi in the world. Climate dynamics and a key gene for adaptive evolution and domestication jointly shaped the mushroom's diversity.
Researchers discovered psilocin's mechanism to reduce alcohol use in female mice by dampening activity of neurons in the central amygdala, leading to decreased drinking. This finding provides mechanistic insight into psychedelic treatment for psychiatric disorders like depression and anxiety.
The increasing use of unregulated psilocybin mushrooms poses a pressing need for public education, potency testing, and age-specific risk assessment. Existing clinical data are insufficient to guide harm reduction or policy, highlighting the need for real-world research on psilocybin use.
Researchers from Ohio State University have developed shiitake-based devices that can act as organic memristors, a type of data processor. These devices demonstrated similar reproducible memory effects to semiconductor-based chips and showed potential for creating low-cost, environmentally friendly brain-inspired computing components.
Researchers discover two distinct methods for producing psilocybin in mushrooms, one in Psilocybe species and another in fiber cap mushrooms. The finding sheds light on convergent evolution and the unique biochemical strategies employed by fungi to produce the same molecule.
A study from the University of Wisconsin-Madison found that golden oyster mushroom invasions decrease fungal community richness and native species numbers. The research, published in Current Biology, used data from tree trunks and community scientist observations to determine the impact on ecosystems.
Empa researchers have developed a bio-based, biodegradable material from fungal mycelium that avoids chemical processing. The material has versatile functional properties, including emulsification capabilities, and is suitable for various applications. Its biodegradability makes it an attractive alternative to traditional materials.
Researchers at UCSF found clinically significant improvements in mood, cognition, and motor function after psilocybin therapy for patients with mild to moderate Parkinson's disease. The study suggests that psilocybin could provide relief from multiple symptoms of the disease by reducing inflammation and promoting neuroplasticity.
Researchers have isolated three new bitter compounds from the mushroom Amaropostia stiptica and found that one of them, oligoporin D, stimulates a specific human bitter taste receptor type at very low concentrations. This discovery expands knowledge of natural bitter compounds and their receptors, which could lead to new applications i...
Researchers suggest that understanding the science behind umami and koku could make plant-based eating more palatable. The authors reveal that key components of umami include free glutamate and nucleotides, while koku is related to small pieces of proteins called dipeptides and tripeptides.
A Japanese research team has successfully synthesized inaoside A, an α-D-ribofuranoside-type compound isolated from the edible mushroom Laetiporus cremeiporus. This achievement paves the way for further investigation into its bioactivities and potential applications in pharmaceuticals and functional foods.
Two studies suggest that psilocybin-assisted psychotherapy can improve mental health outcomes for patients with cancer and alcohol use disorder, reducing symptoms of anxiety, depression, and obsessive thoughts, while also promoting lasting personality changes.
Researchers have discovered that AHCC suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells through two channels. Early administration of AHCC may hold the key to preventing the onset of cirrhosis, a potentially fatal condition.
A systematic review of 45 studies found inconsistent descriptions of psychotherapy sessions, making it difficult to replicate studies and compromise patient well-being. Researchers call for improved reporting standards to enhance the replicability, safety, and potential effectiveness of these therapies.
Mechanical engineering professor Debora Lyn Porter is using a $990,000 grant to research growing fungi into patterns called biotemplating. The goal is to create materials with high strength-to-weight ratio and biodegradability, suitable for aerospace and clothing production.
A study from Emory University reveals that 56-62% of individuals treated for Major Depressive Disorder and Treatment-Resistant Depression are eligible for psilocybin-assisted therapy, which could benefit around 5.1-5.6 million people in the US. The treatment has potential to reduce symptoms of depression with a single dose of 25 mg of ...
A new study found that psilocybin significantly reduced OCD-like behaviors and tic-like head-body twitches in genetically modified mice. The research provides hope for new treatments for these conditions and may offer benefits for patients who have not responded to current therapies.
Muscarine is stored as a phosphorylated precursor and only released when mushrooms are injured, increasing the danger of certain types of fungi.
Researchers found that fungi can communicate information throughout their network and adjust growth patterns based on shape. The mycelial network demonstrated pattern recognition abilities, suggesting a form of cognition that is both fascinating and unexplored in the fungal kingdom.
Researchers successfully designed and engineered novel enzyme systems that can degrade various types of plastics. By replacing the binding module with different modules, they created chimera LPMOs capable of recognizing and breaking down different types of plastics, including biosourced polyhydroxyalkanoate.
Researchers at Cornell University have developed fungus-controlled robots that can react to their environment better than synthetic counterparts. The biohybrid robots use fungal mycelia to sense chemical and biological signals, enabling them to adapt to unexpected situations.
A new study finds that psilocybin temporarily desynchronizes the default mode network in the brain, creating a psychedelic experience. The study provides a neurobiological explanation for the drug's effects and lays groundwork for its potential use as a therapy for mental illnesses.
A study published in Nature used DNA sequencing to identify fungi from air samples worldwide, providing groundbreaking knowledge about their occurrence and seasonal variation. The research aims to predict the fate of fungal species under global change and has significant implications for biomonitoring and biodiversity forecasts.
Researchers from Stellenbosch University and citizen mycologists describe two new Psilocybe species, Psilocybe ingeli and Psilocybe maluti, found in southern Africa. The discovery brings the continent's total to six indigenous species, with potential for more undiscovered species.
A recent study found that multiple Mycena mushroom species have unexpectedly large genomes, suggesting they can adapt to different lifestyles as circumstances change. This discovery has important implications for understanding an organism's habits from their genome sequences alone.
Arctic Mycena mushroom species have unusually large genomes, expanding beyond general Mycena expansion. Genomes show widespread growth across their genome, with genes and elements acquired through horizontal gene transfer.
A new study from Oregon Health & Science University identifies 22 key measures of high-quality psilocybin services, including safety indicators and client outcomes. The study provides a harmonized set of measures for monitoring the safety and effectiveness of these services, as other states consider legalizing psychedelics.
The unregulated sale of Amanita muscaria mushrooms is a growing concern, as they contain compounds similar to fentanyl and can cause hallucinations. Without proper labeling and regulation, these products can put consumers at risk of serious health harm, including death.
A recent Penn State study has discovered that mushroom stump waste can be a nutritious and cost-effective addition to broiler chicken feed. The researchers found that supplementation with up to 3% mushroom stump waste had no negative impact on growth or digestion, but higher levels interfered with amino acid absorption.
Researchers have developed a new paste substrate for cultivating mycelium leather, enabling faster growth and easier harvesting. The study found that this method produces thicker mycelial mats with improved yields, making it a promising sustainable alternative to traditional materials.
Researchers discovered a crucial amino acid exchange that enables PsiM to carry out double methylation during evolution. The enzyme plays a key role in psilocybin production, with implications for biotechnological production of the active ingredient.
Researchers at the University of Texas at Arlington have developed a method to determine the clinical potency of psilocybin and psilocin in Psilocybe cubensis mushrooms. This technique uses liquid chromatography with tandem mass spectrometry, allowing for accurate extraction and measurement of the strength of the mushrooms.
A new study suggests that mushroom extract containing psilocybin demonstrates superior efficacy in stimulating neuroplasticity and promoting new connections between nerve cells. The research found that the extract had a more potent and prolonged impact on synaptic plasticity compared to chemically synthesized psilocybin.
Researchers from Shinshu University have identified Inaoside A, a new antioxidant phenolic compound derived from the edible mushroom Laetiporus cremeiporus. The compound exhibited significant antioxidant activity, including 80% inhibition of DPPH radical scavenging and an IC50 value of 79.9 μM.
Between 2017 and 2022, US law enforcement seizures of psilocybin mushrooms increased dramatically, with the total weight seized peaking in 2021. This trend reflects growing interest in psychedelic use, despite limited self-reported data on prevalence.
Seizures of psilocybin, a hallucinogenic compound found in psychedelic mushrooms, have surged by 369% across the US since 2017, according to a new study. The highest number of seizures were recorded in the Midwest and West regions, with nearly quadrupled amounts of seized drugs.
Researchers have sequenced 52 Psilocybe specimens, including 39 species previously unsequenced, to understand the evolution of psychoactive psilocybin production. The study reveals two distinct gene orders within the psilocybin-producing gene cluster, suggesting an ancient split in the genus.
A team of researchers at Shinshu University has successfully extracted mycelial pulp and fibers from fruiting mushroom bodies using sunlight, preserving their intricate mycelial structures. The fibers show excellent formability and potential applications in packaging materials, textiles, and soundproofing.
A phase II clinical trial found that psilocybin-assisted therapy significantly reduced depressive symptoms in adults with cancer and major depression. Participants who received the therapy experienced a decrease in depression severity scores, with 80% showing sustained responses to treatment.
Researchers sequenced over 100 'magic mushroom' genomes to learn about their domestication and cultivation. They found that commercial cultivars lack genetic diversity, while naturalized populations in Australia maintain more diversity, including unique gene variants controlling psilocybin production.
Mycena fungi have been found to be consistently present in the roots of living plant hosts, suggesting an evolutionary leap from saprotrophic decomposers to invasive species. They also exhibit early signs of mutualism with trees, exchanging nitrogen for carbon and working together to benefit their hosts.
Researchers at the University of Southern Denmark have conducted a study on rats, showing that small doses of psilocybin can increase resilience to stress and reduce compulsive behaviors. The study lends support to the benefits of microdosing as a therapeutic intervention.
Researchers have discovered a novel nursery pollination system in which fungi-eating orchids and fruit flies engage in mutualistic symbiosis. The study found that the orchids offer their flowers to the flies in exchange for pollination, providing a breeding ground for the flies' larvae.
A new study reveals that some US truffle producers are accidentally cultivating winter truffles instead of European black truffles, a more valuable species. The researchers analyzed specimens from 10 anonymous truffle orchards and found that all but one were winter truffles.
Researchers found that psilocybin facilitates fear extinction in mice by promoting hippocampal neuroplasticity. The study's results improve our understanding of the restorative effects of psilocybin on the brain and may lead to alternative treatments for PTSD.
Researchers at University of Southern Denmark discovered that psilocin binds stronger than serotonin to a specific receptor, leading to antidepressant effects. The study's findings have potential implications for treating conditions like severe depression and substance addiction.
Scientists discovered that electrical signals in Laccaria bicolor mushrooms increased after rainfall, demonstrating signal transport among closely spaced mushrooms. The post-rain electric potential showed directionality and strengthened connectivity between spatially close fungi.
A recent study found large groups of fungi that don't form fruiting bodies and can't be grown in labs, highlighting their ecological importance. The authors suggest modifying nomenclature rules to describe these 'dark fungi', which could prove to be the dominant lifestyle in the fungal kingdom.
A new study by University of Stirling scientists found that growing edible mushrooms alongside trees can produce a valuable food source for millions of people while capturing carbon. The approach incentivizes tree planting and reduces the need for deforestation to make way for crops, mitigating the impact of climate change.
Researchers from The University of Queensland have identified new active compounds in Hericium erinaceus that promote neuron projections, extending and connecting to other neurons. This discovery could lead to treatments and protection against neurodegenerative cognitive disorders such as Alzheimer's disease.
Researchers analyzed over 4,500 documents to understand fungal dispersal across spatial scales. They identified four scales of movement, from microscopic to landscape, and found that climate change affects where fungi reside. More data is needed to understand the biodiversity of fungi and their movement in ecosystems.
A study reveals that porcini mushrooms have evolved in different ways across the globe, with local ecological factors playing a stronger role in maintaining genetic distinctiveness than genetic flow. The findings challenge traditional notions of species development and suggest multiple evolutionary strategies for this organism.
Researchers have successfully cultivated Cordyceps mushrooms on edible insects, resulting in significantly higher levels of cordycepin. The study found that insect fat content, particularly oleic acid, plays a crucial role in cordycepin production.
Scientists are conducting a first-of-its-kind study to investigate the origin of psychedelic compounds in fungi, including psilocybin found in 'magic mushrooms'. The research aims to understand the evolution of these compounds and their potential applications in medicine and conservation.
Researchers warn that pharmaceutical companies' pursuit of psychedelic treatments threatens Indigenous and counterculture traditions. Magic mushrooms have spiritual significance for many people, but corporations seeking patents and monopolies on these medicines are being criticized for their approach.
A new study found that psilocybin, combined with psychotherapy, significantly reduced heavy drinking among participants with alcohol dependence. Eight months after treatment, nearly half of those who received psilocybin stopped drinking altogether.