Researchers at Baylor College of Medicine have made significant discoveries about the 3D structure of mammalian ferroportin, revealing two iron-binding sites and a unique mode of action. This new understanding has potential implications for treating iron overload diseases, such as anemia and cancer.
SourceBaylor College of Medicine·JournalNature Communications·DateNov 17, 2020
A study of patients with acute heart failure found that intravenous iron replacement reduced hospital readmissions by 26% after just one or two injections. Iron deficiency is a common complication, and correcting it may be an effective strategy for preventing recurrent hospitalizations.
A new study by Cornell University confirms that teff grain consumption enhances the intestinal microbiome composition and function, potentially explaining lower iron and zinc deficiency rates in Ethiopia. The study used a unique in vivo approach to test the effects of teff seed extracts on living organisms.
Researchers at Arizona State University have developed a new method for creating ultrafast laser experiments on uncharged iron oxide clusters, which could lead to the creation of more efficient industrial catalysts. The study reveals how changes in atomic composition affect stability and reactivity of these fragments.
SourceArizona State University·JournalPhysical Chemistry Chemical Physics·DateNov 10, 2020
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Researchers found that plant-secreted coumarins elicit nutritional assistance from bacterial commensals under iron limitation. Adding synthetic communities of root-associated bacteria improves plant performance on unavailable iron, but not with readily available iron.
SourceMax Planck Institute for Plant Breeding Research·JournalCell Host & Microbe·DateNov 2, 2020
The study provides new insights into the asteroid's composition, suggesting it may be a dense, metallic object made of iron and nickel. The findings also indicate that oxidation is occurring on the surface, which could be a result of solar wind interaction.
SourceSouthwest Research Institute·JournalThe Planetary Science Journal·DateOct 26, 2020
Researchers report that niobium readily dissolves in iron under high temperatures and pressures consistent with the Earth's core formation. This finding supports core formation models suggesting that the core did not form under highly reducing or oxidizing conditions, but rather was constrained by the sequestration of niobium.
SourceProceedings of the National Academy of Sciences·JournalProceedings of the National Academy of Sciences·DateOct 26, 2020
A new study by a USC-led research team reveals that emissions from Chinese coal-fired power plants are fertilizing the North Pacific Ocean with iron and other metals, which could impact marine life. The researchers found peak iron concentrations in surface seawater corresponding to big wind events over east Asia.
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A recent scientific study led by the Centre for Neurology Studies at HealthTech Connex and Simon Fraser University reports breakthroughs in brain health recovery for Captain Trevor Greene, a Canadian veteran who survived an axe attack in Afghanistan. The study used innovative neuro-technologies, including Portable Neuromodulation Stimu...
SourceChiang Public Relations·JournalFrontiers in Human Neuroscience·DateOct 14, 2020
A study by Haizhou Liu and colleagues reveals that corroded cast iron pipes can react with residual disinfectants to form Cr(VI), a known carcinogen. The researchers suggest using less-reactive disinfectants and replacing cast iron pipes with chromium alloy could help mitigate Cr(VI) levels in drinking water.
SourceAmerican Chemical Society·JournalEnvironmental Science & Technology·DateSep 30, 2020
A new study suggests that limited iron levels in corals could impair their ability to respond to climate change. High water temperatures and low iron availability compromise the algae living within coral cells, leading to reduced growth and function.
SourcePenn State·JournalJournal of Phycology·DateSep 30, 2020
University of Alberta scientists uncover formation mechanism behind iron oxide-apatite deposits. They are deposited from a unique liquid dominated by calcium carbonate and sulfate, providing geologists with new clues to guide the hunt for more ore.
SourceUniversity of Alberta·JournalNature Geoscience·DateSep 23, 2020
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Researchers at TU Wien and DESY discovered a material that can be switched between two states: one is catalytically very active, the other less so. The switching is controlled by tiny iron nanoparticles on the surface, which change between metallic and oxidic states depending on the voltage applied.
SourceVienna University of Technology·JournalNature Communications·DateSep 23, 2020
A study published in Geoderma journal reveals that iron minerals and bacteria are main agents of carbon dioxide emissions from soil. Iron facilitates formation of active oxygen forms that destroy plant waste and promote CO2 emissions.
Researchers found high concentrations of hematite at lunar high latitudes, strongly correlated with water content. The presence of hematite suggests that Earth's atmospheric oxygen may have oxidized the mineral over billions of years.
SourceUniversity of Hawaii at Manoa·JournalScience Advances·DateSep 2, 2020
The American Gastroenterological Association (AGA) recommends bidirectional endoscopy for asymptomatic patients with iron deficiency anemia to detect underlying causes such as gastrointestinal malignancy, peptic ulcer disease, and inflammatory bowel disease. Non-invasive testing, including Helicobacter pylori and celiac disease testing...
SourceAmerican Gastroenterological Association·JournalGASTROENTEROLOGY·DateSep 1, 2020
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The study reveals how iron can be used to remove oxygen from plant materials without oxidizing, enabling more efficient and cost-effective fuel production. By anchoring iron with a carbon structure modified with nitrogen, the researchers created a catalyst that interacts less with oxygen, allowing for robust reaction performance.
SourceWashington State University·JournalACS Catalysis·DateAug 19, 2020
Researchers develop potential small molecule inhibitors to disrupt bacterial iron acquisition, offering a new approach against UTI-resistant strains. The target is the TonB system, which helps bacteria take up iron, and promises a safer alternative with fewer side effects.
A study published in PLOS ONE found that captive black rhinoceroses have higher iron levels, inflammation, and oxidative stress compared to white rhinoceroses. This suggests a link between iron accumulation and the development of diseases like organ failure.
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Advanced computer simulation techniques have determined which low-and-middle income countries would benefit from using iron-containing micronutrient powders to tackle childhood anaemia, with 54 out of 78 countries showing a net benefit. Policymakers can use individual reports for each country to balance benefits and risks.
SourceWalter and Eliza Hall Institute·JournalThe Lancet Global Health·DateAug 4, 2020
Researchers have discovered that iron is internalised by CD44, a membrane protein known for its association with metastases. This allows cancer cells to acquire metabolites necessary for the metastatic state.
Researchers found that mussels form weaker attachments in iron-deficient seawater due to altered iron bioavailability. The study reveals a possible consequence of changing ocean chemistry on marine life.
SourceAmerican Chemical Society·JournalEnvironmental Science & Technology·DateJul 29, 2020
Clinical studies in Kenya suggest that iron deficiency during infancy may reduce the protection provided by vaccinations. In one study, researchers found that anaemic infants had more than twice the risk of lacking protective antibodies against diphtheria and other pathogens.
SourceETH Zurich·JournalFrontiers in Immunology·DateJul 28, 2020
Scientists identify ten regions of the genome linked to long lifespan, healthspan, and longevity, finding a potential link between iron metabolism and healthy aging. The study's findings suggest that maintaining healthy levels of iron in the blood could be key to slowing aging and living longer.
SourceUniversity of Edinburgh·JournalNature Communications·DateJul 16, 2020
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Researchers discovered that cancer cells with high-affinity iron collection systems collect iron more efficiently than healthy macrophages, allowing them to survive in nutrient-deprived CSF environments. This mechanism enables LM cells to evade immune attack by limiting the supply of vital iron to patrolling macrophages.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience·DateJul 16, 2020
The geodynamo generates Earth's magnetic field through the motion of liquid iron in the outer core. New research examines how lighter elements like silicon could drive this process, suggesting a concentration of 8 weight percent silicon is sufficient to sustain the geodynamo on heat transmission alone for the planet's entire history.
SourceCarnegie Institution for Science·JournalNature Communications·DateJul 6, 2020
A study links iron levels in a Greenland ice core to Asian dust patterns over the past 110,000 years. The findings suggest that changes in solar radiation drove hemispheric-scale dust input, with more complex Fe fertilization effects during the Holocene.
SourceScience China Press·JournalNational Science Review·DateJul 3, 2020
Researchers found higher brain iron levels associated with cognitive deterioration in Alzheimer's disease, suggesting a potential role for iron chelators in treatment. Iron deposition was linked to amyloid beta and neurofibrillary tangles, disruptors of cell function.
SourceRadiological Society of North America·JournalRadiology·DateJun 30, 2020
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Scientists have accurately measured the density of liquid iron under conditions similar to those at Earth's outer core. The findings suggest that pure iron is about 8% more dense than the Earth's outer core, indicating the presence of other light elements.
SourceKumamoto University·JournalPhysical Review Letters·DateJun 26, 2020
A new iron compound, containing phytate and corn protein hydrolysate, has been found to be easily absorbed by the intestine without compromising food quality. The compound is bound to amino acids and has been shown to increase iron uptake in human intestinal cells, particularly in those with iron absorption inhibitors.
SourceChalmers University of Technology·JournalScientific Reports·DateJun 17, 2020
Research by Dirk Tischler's group has identified potential applications for bacterial siderophores, including treating iron overload disease and creating biosensors. The team has also developed semi-artificial compounds using genetic information from these microorganisms.
SourceRuhr-University Bochum·JournalNatural Product Reports·DateMay 26, 2020
Researchers at MPIE and RUB have found that anharmonicity and segregation affect interstitial ordering in Fe-C steels. The study's findings suggest a critical concentration range for the order-disorder transition, which can be precisely calculated using specific binding energy and defect information.
SourceRuhr-University Bochum·JournalNature Materials·DateMay 14, 2020
Scientists at Trinity College Dublin have discovered that the iron chelator DFX supports lung immunity against tuberculosis by driving the activation of glycolysis, a key metabolic pathway. This process helps immune cells make energy to fight infection and improves macrophages' ability to address TB infection.
SourceTrinity College Dublin·JournalFrontiers in Immunology·DateMay 13, 2020
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A diet of high-iron beans improved the iron status and physical performance of women with anemia in Rwanda. The study shows that biofortified crops can be a sustainable alternative to address nutritional deficiencies in low-income countries.
SourceThe Alliance of Bioversity International and the International Center for Tropical Agriculture·JournalJournal of Nutrition·DateApr 29, 2020
Researchers have developed a multipurpose nanoscale bio-probe that allows precise monitoring of iron disorders in cells, tissue, and body fluids. The test is more sensitive and specific than current blood testing methods, enabling early disease diagnosis and potential prevention of serious diseases.
SourceUniversity of Sydney·JournalACS Applied Materials & Interfaces·DateApr 28, 2020
Microalgae in coral cells may compensate with other metals when iron is limited, potentially affecting vital biological functions. Research found that different species of microalgae acquire other trace metals in unique quantities, which could have cascading effects on coral health.
Researchers have found that elevated ferritin concentrations are associated with increased production of special signalling molecules, leading to complications and death in COVID-19 patients. Marker CD163 is also an important indicator of macrophage activation and high risk of complications.
SourceSt. Petersburg State University·JournalAutoimmunity Reviews·DateApr 22, 2020
Scientists have successfully determined the density of liquid iron and sound propagation speed through it at extremely high pressures. They found the density of the molten outer core to be about 8 percent less dense than pure liquid iron, suggesting the presence of additional lighter elements.
SourceUniversity of Tokyo·JournalPhysical Review Letters·DateApr 15, 2020
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Quantum mechanical simulations show that the Earth's inner core is not as rigid as thought, with a lower iron viscosity than previously predicted. This suggests that plastic flow of iron might contribute to seismic anisotropy and the inner core's alignment.
SourceEhime University·JournalScientific Reports·DateApr 14, 2020
A new study suggests that heavier iron isotopes migrate towards lower temperatures and into the mantle, while lighter isotopes remain in the core. This phenomenon could be causing core material to infiltrate the lowermost mantle, enriching it in heavy iron isotopes.
SourceUniversity of California - Davis·JournalNature Geoscience·DateApr 13, 2020
Researchers identified a protein responsible for transporting iron into bacteria that causes tuberculosis. Inhibiting this transport process could lead to new drug targets and novel treatments.
SourceUniversity of Zurich·JournalNature·DateApr 1, 2020
A recent investigation found that approximately one-third of people with heart failure are not being screened for iron deficiency, leading to avoidable hospital stays and increased costs. The study estimates that this undermanagement results in an additional £21.5 million per year spent on managing co-morbid patients.
SourceCello Health Communications·JournalOpen Heart·DateMar 19, 2020
Research finds that high levels of iron build-up in lung cells worsen asthma symptoms and lower lung function. The study suggests a link between iron absorption, immune system responses, and asthma severity.
SourceEuropean Respiratory Society·JournalEuropean Respiratory Journal·DateMar 17, 2020
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The ESO's Very Large Telescope has observed an ultra-hot giant exoplanet where it rains iron on its night side. Strong winds carry iron vapour from the day side to the cooler night side, where temperatures decrease, resulting in a unique and extreme phenomenon.
Researchers detected chemical variations between day and night on the planet, revealing the presence of iron vapour condensing into drops on the dark side. This discovery provides insights into the extreme climate conditions on ultra-hot giant exoplanets.
SourceInstituto de Astrofísica de Canarias (IAC)·JournalNature·DateMar 11, 2020
Research shows that babies consuming infant rice cereals have higher intakes of key nutrients like calcium, magnesium, iron, zinc, and vitamin E. Baby cereal is associated with better nutrient status and a reduced risk of inadequate intakes of these essential nutrients.
SourcePollock Communications·JournalAIMS Public Health·DateMar 10, 2020
Researchers find tiny iron crystals on asteroid Itokawa's surface, formed by space weathering and the release of iron from troilite minerals. The discovery provides insights into weathering processes on other celestial bodies and helps date asteroids.
SourceFriedrich-Schiller-Universitaet Jena·JournalNature Communications·DateFeb 28, 2020
Researchers have linked enriched chalcophile elements like copper and silver to the end-Cretaceous asteroid impact at the Yucatán Peninsula. These elements were likely supplied to the ocean through processes related to the impact, including iron oxides/hydroxides acting as a carrier phase.
SourceUniversity of Tsukuba·JournalGeological Society of America Bulletin·DateFeb 28, 2020
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A new species of hairy cicada, Maculaferrum blaisi, has been identified from a 100-million-year-old fossil in Labrador. The find sheds light on the region's insect biodiversity during the Cretaceous period, providing insights into the evolution of flowering plants and pollinating insects.
SourceMcGill University·JournalActa Palaeontologica Polonica·DateFeb 21, 2020
Researchers found that the proto-Earth formed within five million years, challenging the idea of slow and random collisions between objects. The study's findings support an alternative theory on planet formation through cosmic dust accretion, which may lead to faster formation of other planets.
SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalScience Advances·DateFeb 20, 2020
A new study by UCL researchers has found a link between iron accumulation in the brain and cognitive decline in people with Parkinson's disease. The study used advanced MRI techniques to detect iron deposits in different brain regions, revealing associations with poor memory and thinking scores.
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Researchers found that Earth's oceans already contain just the right amount of iron, making it unlikely to improve carbon dioxide absorption. Phytoplankton growth is more dependent on organic compounds called ligands, which regulate iron availability.
SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateFeb 17, 2020
Researchers used an X-ray laser to study iron carbenes' behavior when exposed to light. They found that the molecule can respond in two ways, with electrons flowing into devices only about 60% of the time.
SourceDOE/SLAC National Accelerator Laboratory·JournalNature Communications·DateFeb 6, 2020
Research finds that brain iron levels increase during childhood and adolescence, correlating with improved cognitive abilities. Decreased iron levels in certain brain regions are associated with impaired performance on cognitive tasks, highlighting the importance of iron for healthy brain development.
A team of researchers has developed an artificial intelligence method to predict iron deficiency responses in plants, identifying key regulatory elements and transcription factors. This breakthrough can lead to improved plant cultivation by increasing iron uptake in new varieties, enhancing adaptation to poor soil conditions.
SourceHeinrich-Heine University Duesseldorf·JournalPLANT PHYSIOLOGY·DateJan 24, 2020
Researchers discovered that a rise in pH within lysosomes causes iron depletion, leading to cell death and inhibition of proliferation. This finding has implications for understanding and treating diseases, including cancer.
SourceRockefeller University·JournalMolecular Cell·DateJan 23, 2020
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The new technology uses self-rolled-up membrane technology to create compact magnetic induction devices with higher performance and reduced heat dissipation issues. Researchers have successfully boosted the performance of their 3D inductor technology, allowing for tens of millitesla-level magnetic induction.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalScience Advances·DateJan 23, 2020
A recent study published in Science Advances analyzed a shocked meteorite sample, revealing the presence of bridgmanite and metallic iron nanoparticles. Bridgmanite is considered the dominant material in the Earth's lower mantle, making up about 38 volume percent of our planet.
SourceArizona State University·JournalScience Advances·DateJan 10, 2020
A research team at Washington University in St. Louis found that dissolved organic compounds can trigger the mobilization of arsenic in recharged aquifers. When oxygen is introduced into the aquifer, it triggers oxidative dissolution of sulfide minerals, releasing arsenic into the water.
SourceWashington University in St. Louis·JournalEnvironmental Science & Technology·DateJan 9, 2020
Researchers from OU and international partners analyzed ancient dust in rocks to understand the role of atmospheric dust on marine ecosystems 300 million years ago. They found that this ancient dust was much dustier than today, with twice as much bioavailable iron, leading to a massive surge in marine photosynthesizers.
SourceUniversity of Oklahoma·JournalGeology·DateDec 23, 2019
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