Articles tagged with Research Priorities
The Patient-Centered Outcomes Research Institute (PCORI) has awarded two research grants to Group Health, a learning health system in Washington state, totaling $40.7 million. The projects focus on developing tools to improve care for back pain and connecting patients with community resources.
A systematic review of TB interventions in low-and-middle income countries found limited real-world evidence to support their effectiveness and financial value. The authors identified substantial gaps in published evidence for scale-up of these interventions, which may prevent program-wide implementation.
A UK-wide partnership is launching a research priority setting project to identify the most pressing questions in childhood neurodisability treatment. The project aims to prioritize unanswered questions on the effectiveness of treatments, taking into account the views of young people, families, and healthcare professionals.
A prospectus published in the Philosophical Transactions of the Royal Society A outlines key issues and research directions for UK marine science over the next two decades. The publication provides a vision for each field, addressing scientific challenges and technological advances necessary to meet them.
A new study suggests that US health security research is not adequately addressing the needs of a diverse range of threats, including natural disasters. The study found that only 10% of funded projects addressed non-biological threats, while most focused on bioterrorism and emerging infectious diseases.
The European Commission awards the ESC nearly €500,000 to survey European CVD research funding landscape and identify gaps in funding. The CardioScape project will provide intelligence on where cardiovascular research funding is provided and make recommendations for future transnational research strategies.
A study led by the University of Michigan found that doctors tend to spend excessive time on early cases and rush at the end of the list, leading to miscommunication and preventable medical errors. Researchers suggest prioritizing handoff conversations for the sickest patients first to improve patient care and reduce errors.
Patients with mental illness experience shorter waits for assessment and admission during crowded periods, but still face delays compared to other patients. The presence of psychiatric teams may help identify higher priority cases.
Researchers found that TFIIB halts general transcription when DNA damage occurs, enabling cells to prioritize repair and support p53's tumor-suppressing functions. This process allows p53 to bypass the need for TFIIB phosphorylation, activating its target genes vital for DNA damage response.
Key researchers propose standards and guidelines for Rett syndrome research to improve animal study design and transparency. The goal is to shorten the time to effective treatments and accelerate progress towards a cure.
Researchers have identified three black raspberry populations with strong aphid resistance, controlled by multiple genes in two cases and a dominant gene in the third. This breakthrough could help protect fruit production from black raspberry necrosis virus.
A study published in PLOS ONE found that female Komodo Dragons live significantly shorter lives than males, with an average lifespan of 32 years compared to 60 years. The research suggests that females invest excessive energy in building nests and guarding eggs for up to six months, leading to reduced body size and weight.
Cold-induced sweetening in potatoes causes unwanted flavor changes and dark colors. Researchers found that suppressing invertase enzyme activity can enable cold storage without compromising chip or plant appearance. The study provides proof of concept for the importance of invertase in cold-induced sweetening.
The BMJ Group has launched a dedicated US edition of bmj.com, prioritizing clinical and journalistic content relevant to US physicians and researchers. The site now features a homepage with direct-relevance articles and channels prioritizing content of interest to US readers.
Researchers found that Napiergrass is a viable biofuel crop in the Southeast's southern tier, offering advantages such as continued biomass production until the first frost. Further studies are underway to improve yields, fiber content, and disease resistance.
A study by researchers found that when nurse leaders' actions mirror their spoken words regarding safety, unit nurses are more likely to report errors, leading to a stronger commitment to safe practices. This, in turn, results in a reduction in patient treatment errors.
New UNICEF studies emphasize the need to prioritize health services for the poorest populations, showing that focusing on equity can improve health outcomes without sacrificing efficiency. The research reveals significant declines in under-five mortality rates worldwide since 1990, yet challenges remain.
The Euro-26 study examined health, life expectancy, and lifestyles of 26 European cities, identifying major differences within individual urban areas. Key priority areas were found for each city, including depression and anxiety, cancer, and respiratory disease.
The University of Texas at Arlington is developing a universal version of the PanDA workload management system, funded by a $1.7 million grant from the US Department of Energy. The new software aims to improve the analysis of large datasets in particle physics and other fields.
A new feasibility study suggests a generic framework for researcher professional development across Europe, overcoming deficiencies and promoting mobility. The framework aims to support researchers in their career aspirations and provide a common language for describing skills.
The American College of Physicians recommends against routine electrocardiogram (ECG) screening for asymptomatic adults at low risk for coronary heart disease, as it may lead to unnecessary procedures and overtreatment. The Task Force also found inadequate evidence that ECG screening in this population reduces the risk for CHD events.
Research on nano-pesticides is crucial for understanding their fate and toxicity, as well as assessing potential benefits and drawbacks. The development of new pesticides products based on nanotechnology holds promise for reducing environmental contamination, but concerns about human health risks persist.
A research team identified a comprehensive group of genes linked to schizophrenia and developed a prototype predictive test that can accurately assess an individual's risk of developing the disease. The test was able to predict schizophrenia risk in about two-thirds of cases, providing guidance for early intervention and treatment.
A comprehensive list of genes associated with schizophrenia has been identified, enabling the development of a predictive test that can estimate an individual's risk of developing the disease. The test, which predicts schizophrenia risk in about two-thirds of cases, holds promise for early intervention and treatment.
The American Society for Bone and Mineral Research (ASBMR) emphasizes the need for further research to improve treatment guidelines for osteoporosis patients taking bisphosphonates. The organization suggests that more research is necessary to determine the optimal length of therapy, as current recommendations may not be suitable for al...
Despite significant barriers to public outreach, many scientists participate in activities targeted at school-aged children, including women and those with families. The study found that having children was positively correlated with participation in outreach efforts.
Customers are using laptops, phones, and coffee cups to shield themselves from others in cafes, decreasing space turnover and discouraging other patrons. Cafes and coffee shops must now design space to accommodate different customers' needs and consider the impact of personal technology on face-to-face interactions.
Countries with limited health research capacity are mainly small islands and politically isolated nations, according to international experts. Establishing national health research strategies is crucial for public health systems to function and thrive.
Comparative clinical effectiveness research studies will benefit from increased patient and clinician involvement to inform health decisions. The Patient-Centered Outcomes Research Institute aims to produce high-integrity research that incorporates patients' voices, caregivers', and healthcare community members.
Climate change may trigger multiple outbreaks of invasive pests and diseases in Southeast Asia's cassava industry, posing a significant threat to smallholder farmers. The region's multi-billion dollar industry is heavily reliant on the crop for income, with Thailand alone accounting for over 60% of global exports.
A new study from the University of Pennsylvania School of Medicine found that liver cancer patients are less likely to die or become too sick for a transplant while waiting on the list compared to non-HCC candidates. The study suggests re-examining the prioritization criteria used to determine waitlist placement.
The Stroke Progress Review Group identified three priorities: developing valid measurements of neuroplasticity, understanding the impact of experience on brain plasticity after stroke, and translating new restorative therapies into practice. Implementing Specialized Programs of Translational Stroke Research in Recovery is a key priority.
A new research agenda has been developed to strengthen the relationship between science and policy, addressing key questions on scientific advice to governments. The final set of 40 questions includes topics such as designing scientific advisory systems and ensuring early identification of policy issues requiring scientific input.
Research reveals that higher social class is associated with increased unethical behavior, including cheating, lying, and breaking the law. The study suggests that relative privilege and security among upper-class individuals lead to a prioritization of their own interests over others.
Researchers identified six essential security aspects for cloud computing: confidentiality, integrity, availability, utility, authenticity, and possession. Users prioritize these elements based on personal needs, weighing pros and cons to reach a compromise.
Chronic diseases, particularly stroke, are the leading causes of death among older adults in Latin America, India, and China. Education has been shown to have a significant impact on mortality rates, suggesting that efforts to ensure universal access to education could lead to substantial health benefits for generations to come.
The Global Burden of Disease project reveals a mismatch between the world's health issues and published research, with certain conditions disproportionately affecting low-income countries. PLoS Medicine editors emphasize the need for research on understudied risk factors like unmet contraception needs and illicit drug use to address gl...
The American Thoracic Society has recommended that critical care research become less fragmented and account for patient heterogeneity. Key areas of focus include basic science, translational research, clinical research, health service delivery, and education.
Researchers recommend 10 key areas for research, including large cohort studies, interdisciplinary approaches, and the development of new tools and models. Effective public-private partnerships are also essential for advancing understanding of chronic inflammatory diseases.
USDA scientists found that using insecticides specifically targeting whiteflies can reduce the need for broad-spectrum pesticides. The study showed that applying a single dose of whitefly-specific insecticide can control whitefly populations for the rest of the growing season.
The TB Research Movement aims to create a framework for concrete actions to harmonize and synergize TB research efforts globally. The movement is creating a framework for more research and innovation, particularly for the poor and vulnerable populations burdened by TB.
Challenges in LMICs require balanced expensive and low-cost research methods to prioritize problems. Good governance can help optimize resource use, ensuring more effective mental health research.
Professor Doug Hilton has received the 2011 Research Australia Leadership and Innovation Award for his pioneering work on blood formation and signalling. His efforts led to thousands of Australians attending 'Rallies for Research' in support of maintaining medical research funding, ultimately protecting public health care.
A paradigm shift is needed to prioritize health equity in social determinants of health research, according to a recent study. The authors recommend four priority areas for future research and suggest refining norms and standards for monitoring health inequalities.
The Federal Government has released a national strategy for environmental, health, and safety research needs in the field of nanotechnology. The strategy identifies six core categories of research to drive responsible development of nanotechnology, including human exposure assessment, human health, and environment.
The Patient Protection and Affordable Care Act of 2010 promotes a national comparative outcomes research project agenda to optimize evidence-based medicine. High-quality associations will identify research topics for pragmatic clinical trials, while systematic reviews of clinical trials provide optimal evidence-based medicine.
The FUTURAGE Road Map provides a comprehensive European research agenda for ageing, focusing on tackling health inequalities and promoting active ageing. The project's key recommendations include engaging end users of research, improving coordination among existing and future research, and building capacity in ageing research.
Key findings highlight the need for health policy and systems research to improve access and coverage of existing interventions. Epidemiological research is also essential to address knowledge gaps in childhood pneumonia.
The research community must prioritize patients' and clinicians' information needs by consulting them about research priorities. This includes publishing all well-conducted research findings, regardless of results direction or strength, to reduce waste and improve accountability.
Researchers and experts agree on priority research questions focused on problem analysis, interventions, and context-specific support. The study aims to strengthen mental health support in humanitarian settings through tangible benefits.
Researchers have developed new potato lines with genetic resistance to wireworms, a major pest that can cause significant damage to crops. The resistant clones outperformed insecticide-treated potatoes in field trials, suggesting that natural compounds like glycoalkaloids may be protecting the plants.
The article emphasizes the need for a structured approach to health policy and systems research (HPSR), citing its current challenges. To address this, the authors propose establishing dedicated homes for HPSR in universities and independent research institutes.
Bumble bees, like honey bees, are important pollinators of native plants. Entomologist James Strange is studying a generalist named Bombus huntii that could be used in greenhouses in the western United States as a replacement for declining B. occidentalis populations.
The University of Nottingham will conduct cutting-edge research on herd welfare, diet, grazing, health, and disease to deliver benefits directly to British dairy farmers. The five-year programme aims to develop programmes for maintaining the health, welfare, and nutritional status of the national dairy herd at world-class standards.
A study found that North American soybeans have a genetic treasure trove in the form of stress-resistant soybeans from a Swedish village called Fiskeby. The Fiskeby soybeans were highly tolerant to salt, aluminum, drought, high ozone levels, iron deficiency, and toxic soil aluminum.
The Grand Challenges in Global Mental Health Initiative identifies top 40 barriers to better mental health globally, focusing on increasing discoveries in research and improving access to evidence-based care. The initiative seeks to build a community of funders dedicated to supporting research that will significantly improve the lives ...
A global study has identified five key grand challenges in mental health, focusing on integrating screening into primary care, improving medication access, and strengthening training for healthcare personnel. The study aims to guide research funding agencies and clinicians in tackling mental illness worldwide.
A multidisciplinary panel recommends careful, well-designed research on chronic cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis patients. The goal is to evaluate the role of vein widening with angioplasty and potential stent placement in improving symptoms.
The European Commission has allocated an additional 30 million euros to COST, increasing the total budget to 240 million euros for the second half of the EU Seventh Framework Programme. This funding boost is a recognition of COST's governance and potential to drive excellence and innovation in Europe.
Researchers have proposed a new approach to ranking the relevance of research papers using social bookmarking tools. The CiteRank algorithm combines similarity and static rankings to enhance search results. It was found that users preferred recent papers but also rated highly classic papers based on priority rating.