Articles tagged with Laboratories
Researchers from the University of Toronto found that leaders tend to transfer their past cultural experience to new groups, creating ineffective cultures. This 'cultural transfer perspective' highlights the need for leaders to disconnect from their past experiences and analyze current circumstances to create effective cultures.
A mathematical model by BfR reveals that publishing all studies, regardless of results, accelerates knowledge acquisition and reduces unnecessary follow-up studies. Using more test animals in a single experiment increases the likelihood of achieving correct and reproducible results.
Colorado State University chemists are developing biologically friendly coatings to mitigate blood-device interactions in extracorporeal life support systems. These advancements aim to eliminate the need for blood thinners, reducing side effects and improving patient outcomes.
A new SLAS Technology special issue showcases life sciences researchers who are using IoT technologies to optimize laboratory systems. The articles explore various applications of IoT in laboratories, including end-to-end sample tracking, automation, and instrument design.
Researchers found that coral bleaching doubles the mortality rate of disease-resistant staghorn coral genotypes. Maintaining genetic diversity is crucial to prevent further loss in the Florida Reef Tract ecosystem.
A recent study by US Army Research Laboratory scientist Dr. James Schaffer and his collaborators found that users' subjective satisfaction with their decisions is strongly influenced by their cognitive state and traits, not just the system's user experience.
Researchers analyzed brain responses of people reading real news headlines to forecast popularity among readers. Infrequent news readers were better able to predict article success, suggesting they responded more broadly to content value. The study's findings could inform Army initiatives on communication and messaging.
Splicing errors can lead to faulty proteins, increasing disease risk. Researchers analyzed 32,000 DNA sequences to understand the rules guiding RNA processing and improve predictions of genetic mutations' impact on disease risk.
Scientists at U.S. Army Research Laboratory and Johns Hopkins University Applied Physics Laboratory develop software to analyze a robot's ability to self-right from any overturned orientation. The team evaluates the Advanced Explosive Ordnance Disposal Robotic System and determines it can right itself on level ground regardless of its ...
Researchers used fMRI data to analyze brain activity of infrequent and frequent news readers, finding that the former group was better at predicting article popularity. The study suggests that people who don't normally read the news are more representative of general population trends.
A team of researchers from the University of Illinois has developed a new method for canceling noise without requiring ear-blocking headphones. By using wireless IoT networks, they can sense sounds and send them to an earpiece with enough time to produce a better anti-noise signal, effectively canceling out external sounds.
The Association for Molecular Pathology recommends a minimum of 34 critical genes for high-throughput pan-myeloid sequencing tests to standardize clinical practice and improve patient care. The report provides evidence-based guidelines for the management of chronic myeloid neoplasms, including diagnostic and prognostic information.
Researchers at Boston Medical Center have developed a method to identify high-burden communities for drug-resistant tuberculosis in South Africa, tracking changes over five years. The study found that Cape Town townships and informal settlements saw the highest rates of drug-resistant TB.
A simple laboratory score has been developed to diagnose patients with heart attack symptoms, reducing the number of blood tests and time spent in emergency departments. The score can identify patients at risk of subsequent heart issues after discharge.
Researchers create universal platform using magnetite-gold particles for targeted cancer treatments and simultaneous diagnosis. The breakthrough discovery enables therapeutic delivery of drugs to tumor cells while detecting them with magnetic resonance imaging.
The MDI Biological Laboratory has established the Morris Scientific Discovery Fund, providing up to $250,000 per year for eligible research programs. This fund aims to foster short-term pilot project support for research that demonstrates federal funding potential.
A recent study demonstrates the feasibility of producing high-quality DNA sequence data at a laboratory in Indonesia. The research shows that molecular techniques like DNA extraction and PCR can be done using relatively simple methods and inexpensive reagents.
Researchers at a nuclear astrophysics lab achieved an order-of-magnitude increase in normalized brightness after upgrading their accelerator. The new system improved high-voltage source stability and signal-to-background ratio, enabling higher proton beam intensity without damaging targets.
The NY Genome Center will create tools for personalized treatment and tackle questions about tumor biology across genetically diverse populations. Researchers aim to improve outcomes for patients by increasing participation of underrepresented ethnic groups in genomic databases.
Researchers at ULB's IRIDIA laboratory have shown that robots can emerge with the ability to correctly order tasks, enabling complex missions such as disaster rescue. This breakthrough demonstrates a complex cognitive skill emerging from group interactions, paving the way for autonomous robot swarms in various applications.
A new species of dogfish shark, Genie's Dogfish (Squalus clarkae), has been discovered in the Gulf of Mexico and western Atlantic Ocean. The species was identified through genetic testing and morphology, and is named after Eugenie Clark, a pioneering female shark biologist.
A recent study found that antibiotic susceptibility assays may yield unreliable results due to variations in inoculum levels. The findings suggest that clinical microbiology laboratories must adhere closely to standardized methods and target inoculum levels to obtain accurate testing results.
The MDI Biological Laboratory has received a five-year, $12 million NIH Center of Biomedical Research Excellence (COBRE) grant to support its regenerative biology research. The funding will accelerate efforts to develop new drugs for tissue regeneration and extend healthy lifespan.
Researchers at University of Oregon and Oregon State University found that biocompatible gold nanoparticles and surfactants become toxic when combined in a synergistic way, causing 88% mortality rate in zebrafish embryos. The study's new delivery system could serve as an early screening method to detect toxicity and ensure product safety.
Researchers have discovered a new type of small-cell lung cancer (SCLC) with distinct biological signatures, paving the way for developing personalized treatments. The discovery involves a novel transcription factor called POU2F3, which is expressed in a specific subset of SCLC tumors and may be targeted by specific drugs.
A novel index of coronary artery stenosis severity called resting full-cycle ratio (RFR) has been found to be diagnostically equivalent to instantaneous wave-free ratio (iFR). The study, presented at EuroPCR, suggests RFR could identify pressure-based stenosis severity independent of timing within the cardiac cycle.
Researchers at EPFL have invented a new method to examine protein assembly mechanisms in real time using atomic force microscopy. The technique, which uses pulsed laser light, allows for the observation of dynamic processes that were previously impossible to study.
Researchers found increased expression of genes responsible for antibiotic resistance in human clinical infections compared to laboratory experiments. This discovery could help scientists draw more accurate conclusions and provide better information on treating bacterial infections.
A new risk-score tool utilizing laboratory tests effectively identifies COPD patients at high risk of hospitalization due to a flare-up. The tool, known as the LIVE Score, allows for earlier interventions and improved patient care.
The Big Bell Test successfully validated Bell inequalities using a participatory science experiment, where 100,000 people generated random bits via a video game. The results confirm the violation of Bell inequalities, opening new avenues for quantum physics applications.
A team of chemists at Penn State developed a designer's toolkit to construct complex nanoparticles using a simple mix-and-match process. They created a library of 47 distinct nanoparticles with varying materials and shapes, overcoming the bottleneck in laboratory synthesis.
HRL Laboratories joins DARPA's Assured Autonomy program with the Expressive Assurance Case Toolkit (ExACT) to ensure autonomous vehicle systems perform as programmed without unsafe behavior. The tool kit mathematically verifies algorithms lead to safe and reliable system behavior, considering physics and dynamics of the system.
Researchers have identified a therapeutic RNA molecule that corrects the genetic processing error causing familial dysautonomia by enabling human and mouse cells to produce normal levels of IKAP protein. The discovery provides proof of concept for potentially treating this rare disorder.
Researchers at the U.S. Army Research Laboratory developed a new technology that allows soldiers to learn 13 times faster than conventional methods, potentially saving lives. This technique uses low-cost hardware and collaborative filtering to achieve a significant speedup in training compared to state-of-the-art systems.
The Christian Doppler Lab for the Direct-Write Fabrication of 3D Nano-Probes focuses on novel 3D printing technology. The CD lab for Location-Aware Electronic Systems explores radio-based positioning systems for applications where satellite systems are not available.
A UCLA-led team developed a nonsurgical, noninvasive spinal stimulation procedure that allows six people with severe spinal cord injuries to regain use of their hands and fingers for the first time in years. The participants showed substantial improvements after just eight researcher-led training sessions.
Researchers used laser ablation and plasma mass spectrometry to analyze ancient gold items from the Carambolo treasure, discovering a local gold deposit within 2 km of the site. This breakthrough provides new insights into the origin of the metal and its possible connections to ancient trade routes.
Researchers found that users consider personalized apps more trustworthy when consulted about store preferences, leading to better usability and engagement. Higher perceived transparency reduces privacy concerns and boosts user involvement.
Researchers have developed a low-cost, portable laboratory on a phone that works nearly as well as clinical laboratories to detect common viral and bacterial infections. The device was tested with 771 patient samples and found to be accurate in detecting 12 common diseases such as mumps, measles, herpes, and Lyme Disease.
Scientists have created a universal qubit design that can be used to build a quantum computer. The new superconductor qubit is based on a continuous superconducting nano-wire and has proven to be no worse than traditional designs in initial experiments.
Dr. Steven Harrison received the 2018 Richard King Trainee Award for his article on resolving variant interpretations submitted to ClinVar, published in Genetics in Medicine. The award recognizes high-quality research by trainees in genetics and genomics.
The CNRS secured 15 out of 34 French projects funded by the ERC Advanced Grants, marking a significant lead among European hosting institutions. This achievement comes at a time when the CNRS has demonstrated its expertise in various scientific domains.
Researchers at Bigelow Laboratory for Ocean Sciences have developed a statistical method to quantify important ocean measurements from satellite data. This breakthrough enables scientists to calculate concentrations of key particles in the water column, providing insights into ocean dynamics and biogeochemistry.
Researchers created a synthetic material that mimics the active camouflage of a chameleon's skin, changing its color and stiffness in response to mechanical stimuli. The material has potential applications in medicine, particularly in the manufacture of biological implants.
The JAX/Tufts CTSI collaboration aims to strengthen and expand research and training programs in clinical and translational science. Researchers will access Tufts CTSI resources for research design, clinical studies infrastructure, and fellowships.
A team of scientists has discovered that rocks round up in the same way regardless of their origin, with a common process guiding their shape evolution. By combining mathematical models and laboratory experiments, the researchers found that collisions between particles favor the chipping off of small sediment fragments.
A new brain-mapping technology has revealed that neurons in the primary visual cortex communicate with higher visual areas of the cortex more broadly than previously believed, following specific patterns. This discovery could provide a means of linking visual information across the brain to form complex percepts.
Scientists at Linköping University have developed a method to generate electricity from the natural fluctuations in temperature caused by sunlight and shade. By combining plasmonic antennas with pyroelectric materials, they can harness energy from light fluctuations. This innovative technology has the potential to be used in various ap...
A team of plant geneticists at Cold Spring Harbor Laboratory identified a protein receptor on stem cells that issues different instructions depending on the peptide fragment activating it. This multi-functional receptor has important implications for boosting crop yields, particularly in crops like corn and rice.
Scientists at HZDR aim to demonstrate that precession is sufficient to create a magnetic field using liquid sodium. The experiment could provide insights into the geodynamo and clarify the role of precession in generating the Earth's magnetic field.
Researchers created a method to formulate a sequence of yes/no questions that rapidly achieves the best answer, enabling robots to maintain continuous conversation with humans. The study's findings have potential applications in machine-machine questioning and human-robot teaming.
The new edition includes quality management, reflecting the rapidly evolving field of bone marrow transplantation. The standards have been developed through international consensus and are recognized globally among transplantation professionals.
Researchers at Åbo Akademi University and Moffitt Cancer Research Centre are developing AI-driven precision cancer medicine to identify effective multi-drug therapies for each patient. The project combines molecular data with network modelling to analyze interactions between drugs and inhibitors, reducing the risk of drug resistance.
The Association for Molecular Pathology (AMP) has published consensus-based recommendations for clinical CYP2C19 genotyping allele selection. The guidelines aim to standardize testing across laboratories and improve concordance, enabling better patient care.
Researchers at Cold Spring Harbor Laboratory find a genetic mutation that increases grains in sorghum by tripling each plant's yield. By reducing hormone levels, they generate more flowers and seeds.
Researchers found that using more diverse study samples can significantly improve the reproducibility of experimental results in pre-clinical animal research. By combining data from multiple studies, they showed that multi-laboratory studies produce more consistent results than single-laboratory studies.
Researchers created a scaled-down model of an active volcanic plumbing system to study magma flow through dykes. The novel experimental setup revealed the simultaneous measurement of fluid flow, sub-surface deformation during magma ascent, challenging existing thinking on magma flow.
A new technique has been developed to analyze additional chromosomes, which are found in some species and can be associated with developmental abnormalities. The study identified specific regions of the genome present on these additional chromosomes, including genes related to cell cycle control and cytoskeleton structure.
A team of scientists found that Emiliania huxleyi adapted rapidly to ocean acidification, with some lineages exhibiting extremely rapid changes in ecological fitness. However, the algae's ability to adapt did not translate to better survival in natural conditions.
A study by Steve Maren and his team identified a key brain circuit that triggers fear relapse. The research found that the hippocampus is connected to a specific type of cell in the prefrontal cortex, which plays a crucial role in relapse. This breakthrough could lead to more effective treatments for disorders like PTSD.