A new study at Northwestern University has developed a revolutionary tool to rapidly test millions of nanoparticles for specific applications. The novel approach utilizes a combinatorial library, or megalibrary, of nanoparticles and an in situ Raman spectroscopy-based screening technique to identify optimal compositions.
A new study found that the median lifespan increase of Brachionus rotifers varied greatly among genetically distinct strains when exposed to low temperature. The findings indicate that temperature affects lifespan depending on an individual's genes, challenging the long-held free-radical theory of aging.
The COSINE-100 experiment has reported no excess of signal in its data, putting DAMA's annual modulation signal at odds with other experiments. The researchers will need several years of data to fully confirm or refute the claim.
Young aphids use this behavior to quickly return to a safe host plant after escaping from grazing animals. This helps them increase their chances of survival in hostile environments.
The COSINE-100 experiment has released its first results, confirming the absence of a dark matter signal in the data. The study challenges the DAMA claim as a WIMP signal, significantly challenging the traditional Standard Halo Model for dark matter.
A study by researchers from Bigelow Laboratory for Ocean Sciences found that mussels readily take in microplastic fibers but quickly flush most of them out. This suggests that marine animals may play a role in mitigating the impact of microplastics on ecosystems.
A groundbreaking study found that billions of nanoplastics can accumulate in the bodies of marine organisms like great scallops within just six hours. The research, led by the University of Plymouth, showed that even smaller particles measuring 20nm had become dispersed throughout the body's organs.
Vicki P. Losick has been awarded the first-ever William Procter Scientific Innovation Fund to study age-related macular degeneration (AMD) using a fruit fly model. The goal is to identify genetic strategies to treat AMD by understanding the role of polyploidy in human retinal diseases.
The study found a significant increase in test ordering among GPs between 2000/1 and 2015/16, with an average of five tests per year in 2015/16. This has major implications for general practitioners' workload and the NHS budget.
Researchers have successfully used remote servers in Japan to autonomously optimize conditions for synthesizing drugs in a British laboratory. The process was controlled over the internet by researchers in the USA, demonstrating the potential of cloud-based approaches for international collaboration and efficient production processes.
A new study reveals that coral reef fish employ a sequence of well-defined decision rules to generate evasion behavior in complex natural environments. The escape response is influenced by the perceived size and expansion rate of the threat stimulus, as well as the location of nearby safe shelter.
Dr. María Laura Gutiérrez, a young researcher from Argentina, has won the PETA International Science Consortium Award for her work on developing non-animal test methods. The award sends her to an annual workshop at the Institute for In Vitro Sciences, where she will learn hands-on laboratory experience using human cells or tissue models.
A molecular pathway previously studied in laboratory conditions has been verified to be disrupted in Parkinson's disease patients. The study identifies a key enzyme switch that plays a pivotal role in protecting the brain against stress.
Researchers developed a universal light modulator to create complex structures for probing and controlling matter. This architecture generates arbitrary light structures with programmable beamlets, enabling new scientific and technological frontiers in photonics applications that require high power.
Researchers from GFZ found micro-earthquakes prior to a 4.2 magnitude earthquake in June 2016, south of Istanbul. The study suggests that analyzing these small events could extend warning times for future earthquakes in the region.
The four-year project will develop and apply new tools to connect the functions of individual microbes to their genetic makeup in diverse marine and continental environments. Combing single-cell genomics with measurements of microbial metabolism will help understand the role of microbes in cycling biologically important compounds.
A laboratory study of over 100 healthy adults found that pairing larger wins with sensory cues increased participants' preference for high-risk decisions. The researchers also observed greater pupil dilation in subjects who were more aroused when winning outcomes were paired with sensory cues.
Researchers have developed a method to modify the structure of carbon nanotubes, changing their conductive properties. By stretching nanotubes, scientists can create semiconducting nanotubes suitable for microprocessors and high-precision detectors.
The MDI Biological Laboratory has received a five-year, $1.2 million grant from the National Institute of General Medical Sciences to promote data literacy among high school students and teachers. The project aims to address the contamination of well water in Maine and New Hampshire with arsenic, which can lead to severe health problems.
The Universidad Carlos III de Madrid has launched the Laboratory of Discrimination and Inequality (D-Lab), aiming to advance research on discrimination and social inequality. The lab is currently working on projects such as GEMM, analyzing ethnic discrimination in employment across five European countries.
Researchers from the University of Toronto found that leaders tend to transfer their past cultural experience to new groups, creating ineffective cultures. This 'cultural transfer perspective' highlights the need for leaders to disconnect from their past experiences and analyze current circumstances to create effective cultures.
A mathematical model by BfR reveals that publishing all studies, regardless of results, accelerates knowledge acquisition and reduces unnecessary follow-up studies. Using more test animals in a single experiment increases the likelihood of achieving correct and reproducible results.
Colorado State University chemists are developing biologically friendly coatings to mitigate blood-device interactions in extracorporeal life support systems. These advancements aim to eliminate the need for blood thinners, reducing side effects and improving patient outcomes.
A new SLAS Technology special issue showcases life sciences researchers who are using IoT technologies to optimize laboratory systems. The articles explore various applications of IoT in laboratories, including end-to-end sample tracking, automation, and instrument design.
Researchers found that coral bleaching doubles the mortality rate of disease-resistant staghorn coral genotypes. Maintaining genetic diversity is crucial to prevent further loss in the Florida Reef Tract ecosystem.
A recent study by US Army Research Laboratory scientist Dr. James Schaffer and his collaborators found that users' subjective satisfaction with their decisions is strongly influenced by their cognitive state and traits, not just the system's user experience.
Researchers analyzed brain responses of people reading real news headlines to forecast popularity among readers. Infrequent news readers were better able to predict article success, suggesting they responded more broadly to content value. The study's findings could inform Army initiatives on communication and messaging.
Splicing errors can lead to faulty proteins, increasing disease risk. Researchers analyzed 32,000 DNA sequences to understand the rules guiding RNA processing and improve predictions of genetic mutations' impact on disease risk.
Scientists at U.S. Army Research Laboratory and Johns Hopkins University Applied Physics Laboratory develop software to analyze a robot's ability to self-right from any overturned orientation. The team evaluates the Advanced Explosive Ordnance Disposal Robotic System and determines it can right itself on level ground regardless of its ...
Researchers used fMRI data to analyze brain activity of infrequent and frequent news readers, finding that the former group was better at predicting article popularity. The study suggests that people who don't normally read the news are more representative of general population trends.
A team of researchers from the University of Illinois has developed a new method for canceling noise without requiring ear-blocking headphones. By using wireless IoT networks, they can sense sounds and send them to an earpiece with enough time to produce a better anti-noise signal, effectively canceling out external sounds.
The Association for Molecular Pathology recommends a minimum of 34 critical genes for high-throughput pan-myeloid sequencing tests to standardize clinical practice and improve patient care. The report provides evidence-based guidelines for the management of chronic myeloid neoplasms, including diagnostic and prognostic information.
Researchers at Boston Medical Center have developed a method to identify high-burden communities for drug-resistant tuberculosis in South Africa, tracking changes over five years. The study found that Cape Town townships and informal settlements saw the highest rates of drug-resistant TB.
A simple laboratory score has been developed to diagnose patients with heart attack symptoms, reducing the number of blood tests and time spent in emergency departments. The score can identify patients at risk of subsequent heart issues after discharge.
Researchers create universal platform using magnetite-gold particles for targeted cancer treatments and simultaneous diagnosis. The breakthrough discovery enables therapeutic delivery of drugs to tumor cells while detecting them with magnetic resonance imaging.
The MDI Biological Laboratory has established the Morris Scientific Discovery Fund, providing up to $250,000 per year for eligible research programs. This fund aims to foster short-term pilot project support for research that demonstrates federal funding potential.
A recent study demonstrates the feasibility of producing high-quality DNA sequence data at a laboratory in Indonesia. The research shows that molecular techniques like DNA extraction and PCR can be done using relatively simple methods and inexpensive reagents.
Researchers at a nuclear astrophysics lab achieved an order-of-magnitude increase in normalized brightness after upgrading their accelerator. The new system improved high-voltage source stability and signal-to-background ratio, enabling higher proton beam intensity without damaging targets.
The NY Genome Center will create tools for personalized treatment and tackle questions about tumor biology across genetically diverse populations. Researchers aim to improve outcomes for patients by increasing participation of underrepresented ethnic groups in genomic databases.
Researchers at ULB's IRIDIA laboratory have shown that robots can emerge with the ability to correctly order tasks, enabling complex missions such as disaster rescue. This breakthrough demonstrates a complex cognitive skill emerging from group interactions, paving the way for autonomous robot swarms in various applications.
A new species of dogfish shark, Genie's Dogfish (Squalus clarkae), has been discovered in the Gulf of Mexico and western Atlantic Ocean. The species was identified through genetic testing and morphology, and is named after Eugenie Clark, a pioneering female shark biologist.
A recent study found that antibiotic susceptibility assays may yield unreliable results due to variations in inoculum levels. The findings suggest that clinical microbiology laboratories must adhere closely to standardized methods and target inoculum levels to obtain accurate testing results.
The MDI Biological Laboratory has received a five-year, $12 million NIH Center of Biomedical Research Excellence (COBRE) grant to support its regenerative biology research. The funding will accelerate efforts to develop new drugs for tissue regeneration and extend healthy lifespan.
Researchers at University of Oregon and Oregon State University found that biocompatible gold nanoparticles and surfactants become toxic when combined in a synergistic way, causing 88% mortality rate in zebrafish embryos. The study's new delivery system could serve as an early screening method to detect toxicity and ensure product safety.
Researchers have discovered a new type of small-cell lung cancer (SCLC) with distinct biological signatures, paving the way for developing personalized treatments. The discovery involves a novel transcription factor called POU2F3, which is expressed in a specific subset of SCLC tumors and may be targeted by specific drugs.
A novel index of coronary artery stenosis severity called resting full-cycle ratio (RFR) has been found to be diagnostically equivalent to instantaneous wave-free ratio (iFR). The study, presented at EuroPCR, suggests RFR could identify pressure-based stenosis severity independent of timing within the cardiac cycle.
Researchers at EPFL have invented a new method to examine protein assembly mechanisms in real time using atomic force microscopy. The technique, which uses pulsed laser light, allows for the observation of dynamic processes that were previously impossible to study.
Researchers found increased expression of genes responsible for antibiotic resistance in human clinical infections compared to laboratory experiments. This discovery could help scientists draw more accurate conclusions and provide better information on treating bacterial infections.
A new risk-score tool utilizing laboratory tests effectively identifies COPD patients at high risk of hospitalization due to a flare-up. The tool, known as the LIVE Score, allows for earlier interventions and improved patient care.
The Big Bell Test successfully validated Bell inequalities using a participatory science experiment, where 100,000 people generated random bits via a video game. The results confirm the violation of Bell inequalities, opening new avenues for quantum physics applications.
A team of chemists at Penn State developed a designer's toolkit to construct complex nanoparticles using a simple mix-and-match process. They created a library of 47 distinct nanoparticles with varying materials and shapes, overcoming the bottleneck in laboratory synthesis.
HRL Laboratories joins DARPA's Assured Autonomy program with the Expressive Assurance Case Toolkit (ExACT) to ensure autonomous vehicle systems perform as programmed without unsafe behavior. The tool kit mathematically verifies algorithms lead to safe and reliable system behavior, considering physics and dynamics of the system.
Researchers have identified a therapeutic RNA molecule that corrects the genetic processing error causing familial dysautonomia by enabling human and mouse cells to produce normal levels of IKAP protein. The discovery provides proof of concept for potentially treating this rare disorder.
Researchers at the U.S. Army Research Laboratory developed a new technology that allows soldiers to learn 13 times faster than conventional methods, potentially saving lives. This technique uses low-cost hardware and collaborative filtering to achieve a significant speedup in training compared to state-of-the-art systems.
The Christian Doppler Lab for the Direct-Write Fabrication of 3D Nano-Probes focuses on novel 3D printing technology. The CD lab for Location-Aware Electronic Systems explores radio-based positioning systems for applications where satellite systems are not available.
Researchers used laser ablation and plasma mass spectrometry to analyze ancient gold items from the Carambolo treasure, discovering a local gold deposit within 2 km of the site. This breakthrough provides new insights into the origin of the metal and its possible connections to ancient trade routes.
A UCLA-led team developed a nonsurgical, noninvasive spinal stimulation procedure that allows six people with severe spinal cord injuries to regain use of their hands and fingers for the first time in years. The participants showed substantial improvements after just eight researcher-led training sessions.
Researchers have developed a low-cost, portable laboratory on a phone that works nearly as well as clinical laboratories to detect common viral and bacterial infections. The device was tested with 771 patient samples and found to be accurate in detecting 12 common diseases such as mumps, measles, herpes, and Lyme Disease.
Researchers found that users consider personalized apps more trustworthy when consulted about store preferences, leading to better usability and engagement. Higher perceived transparency reduces privacy concerns and boosts user involvement.
Scientists have created a universal qubit design that can be used to build a quantum computer. The new superconductor qubit is based on a continuous superconducting nano-wire and has proven to be no worse than traditional designs in initial experiments.