Articles tagged with Laboratories
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
The Association for Molecular Pathology recommends a minimum of 34 critical genes for high-throughput pan-myeloid sequencing tests to standardize clinical practice and improve patient care. The report provides evidence-based guidelines for the management of chronic myeloid neoplasms, including diagnostic and prognostic information.
A simple laboratory score has been developed to diagnose patients with heart attack symptoms, reducing the number of blood tests and time spent in emergency departments. The score can identify patients at risk of subsequent heart issues after discharge.
Researchers create universal platform using magnetite-gold particles for targeted cancer treatments and simultaneous diagnosis. The breakthrough discovery enables therapeutic delivery of drugs to tumor cells while detecting them with magnetic resonance imaging.
The MDI Biological Laboratory has established the Morris Scientific Discovery Fund, providing up to $250,000 per year for eligible research programs. This fund aims to foster short-term pilot project support for research that demonstrates federal funding potential.
A recent study demonstrates the feasibility of producing high-quality DNA sequence data at a laboratory in Indonesia. The research shows that molecular techniques like DNA extraction and PCR can be done using relatively simple methods and inexpensive reagents.
Researchers at a nuclear astrophysics lab achieved an order-of-magnitude increase in normalized brightness after upgrading their accelerator. The new system improved high-voltage source stability and signal-to-background ratio, enabling higher proton beam intensity without damaging targets.
The NY Genome Center will create tools for personalized treatment and tackle questions about tumor biology across genetically diverse populations. Researchers aim to improve outcomes for patients by increasing participation of underrepresented ethnic groups in genomic databases.
Researchers at ULB's IRIDIA laboratory have shown that robots can emerge with the ability to correctly order tasks, enabling complex missions such as disaster rescue. This breakthrough demonstrates a complex cognitive skill emerging from group interactions, paving the way for autonomous robot swarms in various applications.
A new species of dogfish shark, Genie's Dogfish (Squalus clarkae), has been discovered in the Gulf of Mexico and western Atlantic Ocean. The species was identified through genetic testing and morphology, and is named after Eugenie Clark, a pioneering female shark biologist.
A recent study found that antibiotic susceptibility assays may yield unreliable results due to variations in inoculum levels. The findings suggest that clinical microbiology laboratories must adhere closely to standardized methods and target inoculum levels to obtain accurate testing results.
The MDI Biological Laboratory has received a five-year, $12 million NIH Center of Biomedical Research Excellence (COBRE) grant to support its regenerative biology research. The funding will accelerate efforts to develop new drugs for tissue regeneration and extend healthy lifespan.
Researchers at University of Oregon and Oregon State University found that biocompatible gold nanoparticles and surfactants become toxic when combined in a synergistic way, causing 88% mortality rate in zebrafish embryos. The study's new delivery system could serve as an early screening method to detect toxicity and ensure product safety.
Researchers have discovered a new type of small-cell lung cancer (SCLC) with distinct biological signatures, paving the way for developing personalized treatments. The discovery involves a novel transcription factor called POU2F3, which is expressed in a specific subset of SCLC tumors and may be targeted by specific drugs.
A novel index of coronary artery stenosis severity called resting full-cycle ratio (RFR) has been found to be diagnostically equivalent to instantaneous wave-free ratio (iFR). The study, presented at EuroPCR, suggests RFR could identify pressure-based stenosis severity independent of timing within the cardiac cycle.
Researchers found increased expression of genes responsible for antibiotic resistance in human clinical infections compared to laboratory experiments. This discovery could help scientists draw more accurate conclusions and provide better information on treating bacterial infections.
A new risk-score tool utilizing laboratory tests effectively identifies COPD patients at high risk of hospitalization due to a flare-up. The tool, known as the LIVE Score, allows for earlier interventions and improved patient care.
Researchers at EPFL have invented a new method to examine protein assembly mechanisms in real time using atomic force microscopy. The technique, which uses pulsed laser light, allows for the observation of dynamic processes that were previously impossible to study.
The Big Bell Test successfully validated Bell inequalities using a participatory science experiment, where 100,000 people generated random bits via a video game. The results confirm the violation of Bell inequalities, opening new avenues for quantum physics applications.
HRL Laboratories joins DARPA's Assured Autonomy program with the Expressive Assurance Case Toolkit (ExACT) to ensure autonomous vehicle systems perform as programmed without unsafe behavior. The tool kit mathematically verifies algorithms lead to safe and reliable system behavior, considering physics and dynamics of the system.
A team of chemists at Penn State developed a designer's toolkit to construct complex nanoparticles using a simple mix-and-match process. They created a library of 47 distinct nanoparticles with varying materials and shapes, overcoming the bottleneck in laboratory synthesis.
Researchers have identified a therapeutic RNA molecule that corrects the genetic processing error causing familial dysautonomia by enabling human and mouse cells to produce normal levels of IKAP protein. The discovery provides proof of concept for potentially treating this rare disorder.
Researchers at the U.S. Army Research Laboratory developed a new technology that allows soldiers to learn 13 times faster than conventional methods, potentially saving lives. This technique uses low-cost hardware and collaborative filtering to achieve a significant speedup in training compared to state-of-the-art systems.
The Christian Doppler Lab for the Direct-Write Fabrication of 3D Nano-Probes focuses on novel 3D printing technology. The CD lab for Location-Aware Electronic Systems explores radio-based positioning systems for applications where satellite systems are not available.
A UCLA-led team developed a nonsurgical, noninvasive spinal stimulation procedure that allows six people with severe spinal cord injuries to regain use of their hands and fingers for the first time in years. The participants showed substantial improvements after just eight researcher-led training sessions.
Researchers used laser ablation and plasma mass spectrometry to analyze ancient gold items from the Carambolo treasure, discovering a local gold deposit within 2 km of the site. This breakthrough provides new insights into the origin of the metal and its possible connections to ancient trade routes.
Researchers have developed a low-cost, portable laboratory on a phone that works nearly as well as clinical laboratories to detect common viral and bacterial infections. The device was tested with 771 patient samples and found to be accurate in detecting 12 common diseases such as mumps, measles, herpes, and Lyme Disease.
Researchers found that users consider personalized apps more trustworthy when consulted about store preferences, leading to better usability and engagement. Higher perceived transparency reduces privacy concerns and boosts user involvement.
Scientists have created a universal qubit design that can be used to build a quantum computer. The new superconductor qubit is based on a continuous superconducting nano-wire and has proven to be no worse than traditional designs in initial experiments.
Dr. Steven Harrison received the 2018 Richard King Trainee Award for his article on resolving variant interpretations submitted to ClinVar, published in Genetics in Medicine. The award recognizes high-quality research by trainees in genetics and genomics.
The CNRS secured 15 out of 34 French projects funded by the ERC Advanced Grants, marking a significant lead among European hosting institutions. This achievement comes at a time when the CNRS has demonstrated its expertise in various scientific domains.
Researchers at Bigelow Laboratory for Ocean Sciences have developed a statistical method to quantify important ocean measurements from satellite data. This breakthrough enables scientists to calculate concentrations of key particles in the water column, providing insights into ocean dynamics and biogeochemistry.
The JAX/Tufts CTSI collaboration aims to strengthen and expand research and training programs in clinical and translational science. Researchers will access Tufts CTSI resources for research design, clinical studies infrastructure, and fellowships.
Researchers created a synthetic material that mimics the active camouflage of a chameleon's skin, changing its color and stiffness in response to mechanical stimuli. The material has potential applications in medicine, particularly in the manufacture of biological implants.
A team of scientists has discovered that rocks round up in the same way regardless of their origin, with a common process guiding their shape evolution. By combining mathematical models and laboratory experiments, the researchers found that collisions between particles favor the chipping off of small sediment fragments.
A new brain-mapping technology has revealed that neurons in the primary visual cortex communicate with higher visual areas of the cortex more broadly than previously believed, following specific patterns. This discovery could provide a means of linking visual information across the brain to form complex percepts.
Scientists at Linköping University have developed a method to generate electricity from the natural fluctuations in temperature caused by sunlight and shade. By combining plasmonic antennas with pyroelectric materials, they can harness energy from light fluctuations. This innovative technology has the potential to be used in various ap...
A team of plant geneticists at Cold Spring Harbor Laboratory identified a protein receptor on stem cells that issues different instructions depending on the peptide fragment activating it. This multi-functional receptor has important implications for boosting crop yields, particularly in crops like corn and rice.
Scientists at HZDR aim to demonstrate that precession is sufficient to create a magnetic field using liquid sodium. The experiment could provide insights into the geodynamo and clarify the role of precession in generating the Earth's magnetic field.
Researchers created a method to formulate a sequence of yes/no questions that rapidly achieves the best answer, enabling robots to maintain continuous conversation with humans. The study's findings have potential applications in machine-machine questioning and human-robot teaming.
The new edition includes quality management, reflecting the rapidly evolving field of bone marrow transplantation. The standards have been developed through international consensus and are recognized globally among transplantation professionals.
Researchers at Åbo Akademi University and Moffitt Cancer Research Centre are developing AI-driven precision cancer medicine to identify effective multi-drug therapies for each patient. The project combines molecular data with network modelling to analyze interactions between drugs and inhibitors, reducing the risk of drug resistance.
The Association for Molecular Pathology (AMP) has published consensus-based recommendations for clinical CYP2C19 genotyping allele selection. The guidelines aim to standardize testing across laboratories and improve concordance, enabling better patient care.
Researchers at Cold Spring Harbor Laboratory find a genetic mutation that increases grains in sorghum by tripling each plant's yield. By reducing hormone levels, they generate more flowers and seeds.
Researchers created a scaled-down model of an active volcanic plumbing system to study magma flow through dykes. The novel experimental setup revealed the simultaneous measurement of fluid flow, sub-surface deformation during magma ascent, challenging existing thinking on magma flow.
Researchers found that using more diverse study samples can significantly improve the reproducibility of experimental results in pre-clinical animal research. By combining data from multiple studies, they showed that multi-laboratory studies produce more consistent results than single-laboratory studies.
A new technique has been developed to analyze additional chromosomes, which are found in some species and can be associated with developmental abnormalities. The study identified specific regions of the genome present on these additional chromosomes, including genes related to cell cycle control and cytoskeleton structure.
A team of scientists found that Emiliania huxleyi adapted rapidly to ocean acidification, with some lineages exhibiting extremely rapid changes in ecological fitness. However, the algae's ability to adapt did not translate to better survival in natural conditions.
Researchers at Tohoku University successfully recreated conditions similar to those in space without an electric field-trapping boundary. The study shows the electron gas expands adiabatically when electric fields are removed, demonstrating the extension of classical thermodynamics to out-of-equilibrium systems.
A study by Steve Maren and his team identified a key brain circuit that triggers fear relapse. The research found that the hippocampus is connected to a specific type of cell in the prefrontal cortex, which plays a crucial role in relapse. This breakthrough could lead to more effective treatments for disorders like PTSD.
A new hybrid-capture sequencing assay has been established as the method of choice for detecting 'actionable' gene mutations in lymphoid cancer, with a high accuracy rate of 91%. The assay can be implemented by clinical laboratories into routine diagnostic workflows.
A new study reveals that genetic factors causing autism spectrum disorders diminish brain cognitive functions, leading to lower non-verbal IQ. Motor skills also correlate with de novo mutations in ASD, making them a sensitive indicator of damage.
Researchers recruited 61 PTLDS patients and 26 healthy controls for a comprehensive clinical and laboratory evaluation. They found significant differences in questionnaire results, with PTLDS patients reporting severe fatigue, pain, cognitive complaints, and sleep difficulties.
Researchers have sequenced the genomes of 13 wild and domesticated rice species, revealing valuable genetic information for developing new, efficient, and sustainable rice varieties. The newly created genetic resource provides insights into disease resistance genes, which could help reduce pesticide use and ensure reliable rice harvests.
Researchers developed a model to explore the effect of ocean acidification on coral skeletal growth, finding that acidification influences skeletal density but not extension. The simulation predicted an average decline of around 12.4% in Porites skeletal density across global reef sites by the end of the 21st century.
Researchers from MIT's CSAIL present ColorFab, a method for repeatedly changing the colors of 3-D printed objects after fabrication using custom ink and UV light. The system can recolor a multi-colored object in under 20 minutes, with the goal of reducing waste and increasing customization.
Scientists are exploring a new method to extract high-viscosity oils from challenging reservoirs such as shales and strong sands. The technique involves injecting colloidal solutions of nanosized metal oxide agents, which have shown promise in increasing efficiency and profitability.
A multidisciplinary team has developed software called Scikit-Ribo to more accurately determine when cells translate RNA into protein. This method uses advanced statistical modeling techniques and can filter out noise from previous data, providing a clearer picture of translation dynamics.
A team of geneticists has discovered a mechanism that enables plants to count their chromosomes, solving a century-old problem. They found that small RNA molecules, called miR845, trigger the synthesis of secondary RNAs that silence key genes, preventing viable seeds from forming.
Researchers studied four species of scale-eating fish, finding that each employed distinct strategies to pry scales off prey. The study highlights the diversity of life on Earth and sheds light on the evolution and behavior of these unusual carnivorous grazers.
Scientists discover that training precursor cells in the bone marrow with beta-glucan leads to a sustained positive response of the hematopoietic system. This effect could help accelerate the formation of new white blood cells, which are vital during chemotherapy.