Articles tagged with Scientific Data
Patients with heart failure treated with dapagliflozin experienced frequent initial estimated glomerular filtration rate declines, but without increased cardiovascular or kidney event risks. The study suggests that sodium-glucose cotransporter-2 inhibitors can be safely continued in patients experiencing eGFR decline.
Researchers from the University of Konstanz and Tübingen have found genetic evidence of a woolly rhinoceros's presence in southern Germany during the late Middle Palaeolithic period. The analysis of hyena coprolites reveals that the animals preyed on and consumed woolly rhinoceroses, providing insights into prehistoric ecosystems.
A new study presents a nationwide survey of children and adults with food allergies, revealing common themes around when their allergy developed and coinciding events. The research suggests that eating too much of an allergenic food or genetics may be contributing factors to adult-onset food allergies.
The Southwest-Midwest Pediatric Device Innovation Consortium has supported over 200 pediatric device innovators and companies, developing several devices in the past five years. The consortium's portfolio includes real-world evidence research projects using digital tools for collecting and analyzing patient data.
The American College of Rheumatology has developed five new quality measures to improve lupus care, focusing on steroid use, mental health support, and patient-reported outcome measures. The measures aim to address long-standing inequities in care and reduce lupus-related morbidity by 2030.
Researchers found that changing treatment can lead to significant improvement in mobility and quality of life for patients with advanced Parkinson's disease. A nationwide registry is planned to develop scientifically sound guidelines for combination therapies.
Researchers developed personalized risk equations using AI to identify individuals at high risk of sudden cardiac death. The analysis found that AI was able to accurately predict sudden cardiac death in over one-fourth of all cases, highlighting the potential for AI to revolutionize prevention strategies.
Research highlights the association between traumatic events and insufficient/excessive sleep duration in US children. The analysis of over 100,000 children found that traumatic events magnify the adverse effects of poor sleep on cardiovascular health.
A study found that Black and Hispanic cardiac arrest survivors are less likely to be treated at high-performing hospitals, leading to lower survival rates and poorer neurological outcomes. The research analyzed health records from the Cardiac Arrest Registry to Enhance Survival and found disparities in hospital quality measures.
A study found that Black and Hispanic cardiac arrest survivors were less likely to be treated at top-performing hospitals. The analysis of health records from the Cardiac Arrest Registry to Enhance Survival (CARES) revealed significant disparities in hospital quality measures based on race/ethnicity.
Researchers have reconstructed a global history of water over the past 2,000 years, showing that the global water cycle has changed during periods of higher and lower temperatures. The study found that when global temperature is higher, rain and other environmental waters become more isotopically heavy.
Experts recommend breaking with the past to develop a new international mechanism for sharing benefits from digital sequence information. The current system is threatened by the emergence of fast genome sequencing technologies and open access infrastructures.
A new study reveals that women with atrial fibrillation (AF) have comparable outcomes to men when undergoing pulsed field ablation (PFA), a safer and more precise procedure. The results show improved AF recurrence rates in women after PFA, making them an eligible candidate for this life-enhancing treatment.
A new study finds that heat-related cardiovascular deaths may more than double in the US by the middle of the century, with elderly and Black adults being most at risk. The projections suggest that reducing greenhouse gas emissions can mitigate this impact, but infrastructure interventions such as increasing tree cover may also be effe...
A community-developed set of guidelines aims to improve image publication standards, enhancing reproducibility in scientific research. The guidelines cover formatting, color handling, and annotation, providing a framework for scientists to follow.
Researchers found that shareholders generally welcomed news of green acquisitions, especially when buyers have developed marketing expertise. They also discovered that benefits are buffered if buyers belong to industries sensitive to environmental regulations. This suggests investors can tell genuine from fake green efforts.
A new analysis method can map individual company-level connections, revealing up to 13 billion supply connections worldwide. This data could reduce tax evasion (€130 billion) and improve climate and human rights compliance by creating a global supply network map.
Clinical quality registries collect and store health information to optimize healthcare and management in ICUs, providing valuable data for scientific research and epidemiological maps. The review highlights the role of CQRs in benchmarking strategies between hospitals and improving resource management.
The High Performance Data Facility Hub will provide researchers with unprecedented data management resources, accelerating scientific discovery through seamless access to large and complex datasets. The hub will be led by Jefferson Lab and partner with Lawrence Berkeley National Laboratory.
A large-scale prospective study identified significant variations in the gut microbiome of individuals who developed pre-cancerous colonic lesions. These findings suggest that the microbiome could act as a valuable tool to improve existing tests, advancing early detection methods for colorectal cancer.
Researchers from the University of Virginia Health System have made significant discoveries about the genetic influences on fatty acid metabolism in diverse populations. The study found broad similarities among groups but also notable differences, highlighting the need for genetic studies in diverse groups.
The study reports that UK natural science collections hold over 137 million items and contribute significantly to scientific, commercial, and societal benefits. Digitalizing these collections can unlock a seven- to ten-fold economic return on investment.
A new national ALS research consortium, Access for All in ALS, has been launched with a $16.7 million NIH award. The consortium will include 34 clinical sites nationwide and generate a longitudinal biorepository linked to detailed clinical information.
Researchers at Cornell University have characterized volcanic ash samples from 40 explosive eruptions to provide a comprehensive dataset. The study found that the composition of volcanic ash varies significantly with grain size, tectonic setting, and chemistry, particularly in finer particles where salts increase and glass and iron oxi...
The EBMT has introduced an upgraded patient Registry database to improve data collection, retrieval, and analysis in haematopoietic cell transplantation (HCT) research. The new platform offers enhanced features for healthcare professionals and researchers to access clinical data effectively.
Researchers from FAU's College of Engineering and Computer Science employ a computer-vision deep learning technique to analyze wall-bounded turbulent flows. They successfully identify the sources of extreme events in a data-driven manner, providing new insights into non-linear relationships in fluid dynamics simulations.
The MIT Press is expanding its shift+OPEN initiative with a $275,000 NSF grant to flip two high-impact subscription-based journals to diamond OA. The program aims to accelerate STEM and HSS research by providing barrier-free access to scholarly works.
Ghana has adopted a citizen science approach to address marine plastic litter, leveraging existing data and networks to inform policies and global SDG monitoring. The initiative has become a success story, providing valuable insights for other countries to incorporate citizen science into their SDG efforts.
A new study published in the Journal of the American Heart Association found that improvements in socioeconomic status are not equally beneficial for all racial or ethnic groups. Higher socioeconomic status is linked to better heart health, but this link is greatest among white adults compared to people in other groups.
Preclinical data shows GP-2250's antineoplastic activity in pancreatic tumor cell lines, reducing ATP levels and inhibiting NF-kB. The compound targets aerobic glycolysis, a hallmark of cancer metabolism, providing a potential treatment for various cancers.
A comprehensive global analysis found that these stop-smoking aids are nearly twice as effective as single forms of NRT. Dual forms of NRT, such as combining a patch with gum or a lozenge, were found to be nearly as effective as nicotine e-cigarettes and prescription medications.
The Louisiana Clinical & Translational Science Center has received a $1.3 million NIH grant to support the creation of a network of data warehouses for healthcare providers and researchers in Baton Rouge. The project aims to enhance research capacity, address health care disparities, and improve patient engagement.
A new spatial database created by Purdue University scientists combines data collected on-site and via satellite to provide detailed maps of planted forests in East Asia. The database lists the most common tree species growing there, such as pine and eucalyptus, and covers 87.0% of planted forest in China.
A recent analysis of data from New Jersey found that the rate of hospital visits for self-harm and suicide attempts remained relatively stable, but diagnoses of suicidal ideation increased significantly over a 12-year period. The study suggests that changes in healthcare screening recommendations and coding regulations may be driving t...
A new how-to guide for building big team science projects helps researchers manage collaborative efforts by identifying consensus buy-in, sharing data and collaborating on writing. The guide outlines best practices and overcoming challenges in governance, authorship, and credit management.
Researchers found that people with high blood pressure while lying flat on their backs had a higher risk of heart attack, stroke, and premature death. The study suggests that measuring blood pressure in different body positions may help identify cardiovascular disease risk.
A recent study found a three-fold increase in obesity-related heart disease deaths in the US between 1999 and 2020. The study highlights racial disparities, particularly among Black women, who faced the highest rates of obesity-related cardiovascular mortality.
A new study published in BioScience documents the progress of the InvaCost endeavour, which has compiled data on the economic cost of biological invasions. The database now includes over 13,553 entries and provides a clear picture of the major threats posed by invasive species to ecosystems, biodiversity, and human well-being.
The American Heart Association introduces principles for data sharing to advance patient outcomes, highlighting transparency and privacy concerns. The new policy statement aims to protect patients' sensitive information while facilitating valuable research discoveries.
The guidance paper outlines reliable methods and research practices for improving evidence syntheses. It emphasizes the need for proper education in methodology and cautions against relying solely on appraisal tools and software programs.
A new essay highlights how news stories about healthcare workers during COVID-19 often left out crucial socioeconomic and environmental contexts, which can impact consumer thoughts and responses. By introducing a public health framework, experts aim to broaden storytelling and reframed scientific information dissemination.
Researchers investigating early liver transplantation for alcohol-associated liver disease aim to understand who benefits most and develop best practices. They will collect data on patient outcomes, biological samples, and audio recordings to identify factors influencing selection decisions.
The CABINET trial showed statistically significant and clinically meaningful improvements in progression-free survival for patients with pancreatic and extra-pancreatic neuroendocrine tumors. The study also demonstrated a consistent safety profile for cabozantinib, with no new safety signals identified.
A new study published in the Journal of the American Heart Association found that people who experience pain after a heart attack are more likely to die within the next 8.5 years. The study analyzed data from over 18,300 adults who had a heart attack and found that moderate or extreme pain was linked to a higher mortality risk.
A new study found consistent increases in premature cardiovascular disease (CVD) death and disability due to particulate matter air pollution globally. The analysis, published in the Journal of the American Heart Association, revealed a 8.1% rise in age-standardized CVD deaths attributed to outdoor PM pollution between 1990 and 2019.
A systematic review demonstrates that citizen science has the potential to monitor 48 out of 58 health and wellbeing-related indicators, primarily at local and community levels. Citizen science can increase data availability, quality, and timeliness, filling critical gaps in monitoring efforts.
Genome analysis reveals that hulled and naked oat varieties were domesticated independently around 51,000 years ago. The study found higher genetic diversity in naked oat compared to hulled oat, contradicting the long-held assumption of a recent mutation.
A study found that taking more daily steps improves symptoms and physical limitations for people with heart failure, with little association seen beyond 5,000 steps. Participants who increased their step counts experienced improved symptom control and physical function.
GOBI overcomes model-free and model-based inference method limitations by introducing an easily testable condition for a general monotonic ODE model to reproduce time-series data. It successfully infers positive and negative regulations in various networks, distinguishing between direct and indirect causation.
The Biodiversity Knowledge Hub (BKH) is a one-stop portal providing access to FAIR biodiversity data and services. It enables researchers to navigate linked data, tools, and services across the entire biodiversity research cycle.
The digitization of Johanna Bonne-Wepster's field notes has filled significant gaps in mosquito research and tropical medicine. The collection contains valuable information on vector-borne diseases and their spread, which can inform current public health issues and future disease modeling.
A significant rise in ADHD diagnoses and prescriptions was observed in the UK over the past two decades, with a higher increase among adults. The study found that ADHD was more commonly diagnosed in children and boys than girls and women, and that the number of individuals receiving medication for ADHD increased significantly.
A new study found critical gaps and disparities in access to Parkinson's disease care among Medicare beneficiaries. Only 9% of people with Parkinson's disease receive care from movement disorder specialists.
Researchers found that investors evaluate a company's environmental performance based on financial materiality, providing a better perspective for understanding environmental risks. The study analyzed data from 1,766 companies and identified three key findings: varying evaluation criteria, shareholder risk perception, and the importanc...
Researchers demonstrate that AI language models like ChatGPT can generate high-quality fraudulent medical articles with standard sections and references. The study highlights the need for increased vigilance and enhanced detection methods to combat potential misuse of AI in scientific research.
A recent international study of over 745,000 adolescents from 41 countries found a decrease in those who overestimate their weight and an increase in those who underestimate it. This shift could reduce the effectiveness of public health interventions aimed at weight reduction in young people, as they may make unhealthy lifestyle choices.
Researchers develop an ionic device utilizing redox reactions to achieve a high number of reservoir states, enabling efficient complex nonlinear operations. The device demonstrated remarkable performance in solving second-order nonlinear dynamic equations and predicting future values with low mean square prediction error.
A new study published in NEJM Evidence validates a predictive AI biomarker for androgen deprivation therapy (ADT) benefit in prostate cancer. The study found that personalized use of short-term ADT could improve patient outcomes in men with predominantly intermediate-risk prostate cancer.
Researchers analyzed scientific literature from 1990 to 2021 and found that environmental pollution through chemicals is less studied than other causes of global biodiversity loss. The team calls for a stronger interdisciplinary focus to better understand and mitigate chemical impacts on biodiversity.
A new analysis re-conceptualizes Colin Kaepernick's NFL lock-out as a denial of his 'right to work' due to structural racism and white supremacy. Researchers compared Kaepernick's case to those of six other Black male athletes who faced similar challenges, finding that he was unfairly penalized for protesting systemic issues.