Mount Sinai researchers catalogued thousands of sites in the brain where RNA is modified throughout the human lifespan, increasing with age. This study provides a model depicting how A-to-I editing evolves over a lifetime, shedding light on its role in health and disease.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalCell Reports·TypeData/statistical analysis·DateNov 1, 2022
A new technique combines holographic microscopy with deep learning to follow individual microscopic organisms in the ocean. The method allows for continuous measurement and quantification of micro-zooplankton and feeding events, revealing key interactions between species.
Researchers from North Carolina State University have developed a new method for identifying genes relevant to the aging process in the C. elegans roundworm model. By exposing thousands of worms to random genetic mutations, they can pinpoint which genes are associated with protein aggregation and reduced lifespan.
SourceNorth Carolina State University·JournaliScience·TypeExperimental study·DateNov 1, 2022
Researchers discovered that stopping GH activity in fat cells improves health and increases lifespan in mice. The study found approximately 23% lifespan extension due to GHR disruption, with improved insulin sensitivity and reduced frailty scores.
SourceOhio University·JournalEndocrinology·TypeExperimental study·DateOct 26, 2022
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A new study from the University of South Australia found that severe vitamin D deficiency is associated with a higher risk of mortality. The research evaluated 307,601 records from the UK Biobank and found that individuals with low vitamin D levels had a significantly decreased risk of death over a 14-year follow-up period.
SourceUniversity of South Australia·TypeData/statistical analysis·DateOct 25, 2022
Scientists at NTU Singapore have found that a stress response in cells, when 'switched on' at a post-reproductive age, could be the key to slowing down aging. The study showed that this stress response extended the lifespan of roundworms fed a high-glucose diet.
SourceNanyang Technological University·JournalNature Communications·DateOct 19, 2022
A study found that each 10% increase in natural space is linked to a 7% fall in early deaths among under 65s. Increased availability of natural space within local areas also reduced the disparity in years of life lost between deprived and non-deprived areas.
SourceBMJ Group·JournalJournal of Epidemiology and Community Health·TypeObservational study·DateOct 17, 2022
A team of researchers has identified multiple candidate genes that influence longevity in mice, with subtle genetic variations leading to different health outcomes as we age. The discovery is significant, as it may lead to the development of effective treatments for human aging and diseases.
SourceUniversity of Texas Health Science Center at San Antonio·JournalScience·TypeExperimental study·DateOct 12, 2022
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers from UTHSC and EPFL identified genetic determinants of longevity, with sex-specific regions and non-genetic effects like early growth and access to food affecting lifespan. The study provides a basis for future therapies targeting aging genes and enhancing healthspan.
SourceUniversity of Tennessee Health Science Center·JournalScience·DateOct 5, 2022
A new study found that depleting riboflavin in Caenorhabditis elegans worms extended their lifespan by 30%, promoting a favorable energetic state and activating protective pathways. This discovery offers a novel approach to longevity and metabolic diseases, such as Type 2 diabetes and fatty liver.
SourceMassachusetts General Hospital·JournalAging Cell·TypeExperimental study·DateOct 3, 2022
Researchers find nematodes have two independent ageing processes, one determining movement cessation and the other death time, correlated with each other. This challenges the concept of a single biological age measure indicative of overall health.
SourceCenter for Genomic Regulation·JournalPLOS Computational Biology·TypeExperimental study·DateSep 29, 2022
Scientists have made a groundbreaking discovery about the role of 'junk' DNA in neurological disorders such as Motor Neurone Disease and Alzheimer's. The research found that breaks in this type of DNA can lead to oxidative genomic damage, which can accelerate aging and disease progression.
SourceUniversity of Sheffield·JournalNature·TypeExperimental study·DateSep 28, 2022
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A study by the University of Bristol and Namibian Ministry found no statistically significant differences in population growth factors between dehorned and horned black rhinos. The research suggests that dehorning is not a hindrance to black rhino reproduction or survival, reassuring its use as an anti-poaching deterrent.
SourceUniversity of Bristol·JournalEuropean Journal of Wildlife Research·TypeObservational study·DateSep 21, 2022
Researchers found that mTOR inhibition is crucial for p53-mediated tumor suppression, delaying cancer and increasing lifespan. In the absence of mTOR inhibition, cancer-promoting senescent cells drive tumor growth.
SourceImpact Journals LLC·JournalOncoscience·TypeCommentary/editorial·DateSep 12, 2022
Researchers from Tokyo Metropolitan University have developed a method to directly measure the strength of skeletal muscle myotubes by analyzing wrinkles formed on an elastic substrate when stimulated with electric pulses. This new technique is more sensitive than existing measures and has great potential for accelerating drug discover...
SourceTokyo Metropolitan University·JournalScientific Reports·DateSep 3, 2022
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
A new study reveals that ant queens implement a dual-control system for insulin to promote egg development while slowing down the aging process. This unique mechanism allows ants to live longer and reproduce more effectively, unlike other animals.
SourceUniversity of Florida·JournalScience·TypeExperimental study·DateSep 1, 2022
Queen ants live much longer than workers by generating an anti-insulin protein that blocks aging pathways. This protein enables pseudoqueens, female worker ants that become queens, to reproduce and live longer without aging.
SourceNew York University·JournalScience·DateSep 1, 2022
A recent study published in the Journal of Aging and Physical Activity found that higher levels of light physical activity and moderate-to-vigorous physical activity were associated with lower risk of death. In contrast, higher sedentary time was linked to increased mortality risk, regardless of genetic predisposition for longevity.
SourceUniversity of California - San Diego·JournalJournal of Aging and Physical Activity·TypeObservational study·DateAug 24, 2022
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A study led by UMD researchers found that hibernating big brown bats experience slower epigenetic aging, with their biological clock extending by nearly a year. The study established the link between hibernation and longer lifespans in small mammals.
SourceUniversity of Maryland·JournalProceedings of the Royal Society B Biological Sciences·DateAug 9, 2022
Recent studies show that grape consumption can reduce fatty liver and extend lifespans, with Dr. John Pezzuto's team finding changes in genetic expression and antioxidant genes in mice. Adding grapes to a high-fat diet also had positive effects on behavior and cognition.
SourceCalifornia Table Grape Commission·JournalFoods·TypeExperimental study·DateAug 8, 2022
A Kessler Foundation neuroimaging study found that older individuals reported less state fatigue and showed greater brain activation to combat fatigue. The study also revealed women show greater resilience when faced with a fatiguing task, highlighting age and gender differences in fatigue responses.
SourceKessler Foundation·JournalFrontiers in Neuroscience·TypeImaging analysis·DateAug 5, 2022
A new study on parabiosis found that young mice exposed to old blood experienced a significant decrease in lifespan. The research suggests that aging factors in older blood can induce aging in younger animals, challenging the idea that 'young' blood holds anti-aging properties.
SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalRejuvenation Research·TypeExperimental study·DateAug 4, 2022
A statistical analysis of 200 years of data across all continents reveals that between 25-50% of men outlive women, particularly in developed countries. The study highlights the impact of education, marital status, and external factors on sex differences in lifespan.
SourceBMJ Group·JournalBMJ Open·TypeData/statistical analysis·DateAug 2, 2022
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A study of 1,813 older women found that accelerated biological aging is associated with lower odds of living to be 90 years old and maintaining physical and cognitive function. Slower age acceleration was linked to a reduced risk of mortality.
SourceUniversity of California - San Diego·JournalJAMA Network Open·TypeObservational study·DateJul 27, 2022
Research from the University of Georgia suggests that a diet rich in bright-colored fruits and vegetables, particularly those high in lutein and zeaxanthin, can help prevent visual and cognitive loss in women. This is due to the antioxidant properties of these carotenoids, which have been shown to improve central nervous system degener...
SourceUniversity of Georgia·JournalNutritional Neuroscience·DateJul 14, 2022
Researchers found global redistribution of histone H3 modifications with time, particularly in intergenic regions and near transcription start sites. Caloric restriction diet feeding reduced the extent of changes occurring during the first year of life in these genomic regions.
SourceImpact Journals LLC·JournalAging-US·TypeExperimental study·DateJun 30, 2022
Researchers analyzed stored blood samples from infected men and found significant age acceleration in DNA epigenetic measures and telomere shortening. The study demonstrates HIV's substantial impact on the body's aging processes within two to three years of infection.
SourceUniversity of California - Los Angeles Health Sciences·JournaliScience·TypeRandomized controlled/clinical trial·DateJun 30, 2022
A comprehensive study reveals that turtles, crocodilians, and salamanders have low aging rates and extended lifespans. Protective phenotypes like hard shells contribute to slower aging, with some species experiencing 'negligible aging' or lack of demographic aging.
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A systematic review evaluated patient-reported outcome measures assessing health-related quality of life for adults and adolescents with acne. The review found that these measures can provide valuable insights into the impact of acne on patients' lives, highlighting the need for better standardization and evaluation of these tools.
The University of Minnesota is studying how various levels of discrimination affect mental, physical, and social health. The study aims to develop interventions that promote health equity by addressing individual, neighborhood, institutional, and societal/policy levels of structural racism.
SourceUniversity of Minnesota Medical School·DateJun 20, 2022
A recent study published in the Journal of the American Geriatrics Society found that higher levels of optimism are associated with longer lifespans and a greater likelihood of living past 90 years of age. Lifestyle factors accounted for nearly one-quarter of the optimism-lifespan association across racial and ethnic groups.
SourceWiley·JournalJournal of the American Geriatrics Society·DateJun 8, 2022
A study published in Journal of the American Geriatrics Society found that higher levels of optimism were associated with longer lifespan and living beyond age 90 in women from diverse racial and ethnic groups. Optimism was linked to a 5.4% longer lifespan and a 10% greater likelihood of living beyond 90 years.
SourceHarvard T.H. Chan School of Public Health·JournalJournal of the American Geriatrics Society·TypeObservational study·DateJun 8, 2022
Buck Institute researchers found that dietary restriction can extend lifespan in fruit flies due to changes in their circadian rhythms, particularly in the eye. The study suggests that the eye plays a role in regulating lifespan, which may have implications for human health and aging.
SourceBuck Institute for Research on Aging·JournalNature Communications·TypeExperimental study·DateJun 7, 2022
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Biologists at the University of Rochester have identified two key systems controlling gene expression related to longevity: circadian networks regulating negative lifespan genes and the pluripotency network controlling positive lifespan genes. This research provides new insights into understanding how longevity evolves and may lead to ...
SourceUniversity of Rochester·JournalCell Metabolism·DateMay 31, 2022
Researchers discovered that a conserved receptor molecule called Tom70 coordinates the balance between protein production and import into mitochondria. This finding ties to increased lifespan and delayed mitochondrial dysfunction when Tom70 levels are elevated. The study provides new insights into aging and age-related diseases.
SourceBuck Institute for Research on Aging·JournaleLife·TypeExperimental study·DateMay 18, 2022
A recent study published in Obesity Reviews found that resistance training, in conjunction with a reduced calorie diet, can lead to significant fat mass and muscle loss. This breakthrough highlights the importance of considering non-aerobic exercise options for individuals struggling with obesity.
SourceEdith Cowan University·JournalObesity Reviews·TypeMeta-analysis·DateMay 15, 2022
A new study from Pennington Biomedical Research Center found that FGF21 is critical for extending lifespan and improving metabolic health in mice fed a low-protein diet. Without FGF21, mice fail to adapt to the diet and exhibit detrimental effects on health.
SourcePennington Biomedical Research Center·JournalNature Communications·TypeExperimental study·DateMay 13, 2022
Dr. Blagosklonny discusses the potential of combining rapamycin with other modalities to live long enough to benefit from future discoveries in cellular reprogramming. He emphasizes that Altos Labs needs to develop rapamycin-based drug combinations to achieve additional decades of life extension, potentially within 3-5 years.
SourceImpact Journals LLC·JournalOncoscience·TypeCommentary/editorial·DateMay 11, 2022
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers found that restricting calories and eating at the right time of day can lead to a longer, healthier life. Mice on a reduced-calorie diet lived up to 35% longer when fed at night, extending their median lifespan by nine months.
SourceHoward Hughes Medical Institute·JournalScience·DateMay 5, 2022
The new COBRE grant will help WVU recruit researchers and clinician-scientists to develop innovative solutions for preventing and treating incurable vision problems. The project aims to reduce visual disparities in West Virginia by understanding the complex combination of factors that contribute to these problems.
A multi-pillar approach to nutrition can help increase lifespan by promoting optimal carbohydrate intake from non-refined sources, low but sufficient protein from plant-based sources, and enough plant-based fats. The 'longevity diet' may also involve intermittent fasting and a 5-day cycle of a fasting or fasting-mimicking diet every 3-...
SourceUniversity of Southern California·JournalCell·TypeMeta-analysis·DateApr 28, 2022
A new study examines how individual electrode particles contribute to battery decay and identifies key factors, including particle properties and interactions. The research aims to develop techniques to control these properties and design more efficient, long-lasting batteries.
SourceVirginia Tech·JournalScience·TypeComputational simulation/modeling·DateApr 28, 2022
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
Researchers found that wealth was associated with a 19 percentage point increase in survival rates from age 65 to 85, but smoking dominated other factors in shortening lifespan. The study suggests that avoiding smoking is crucial for living longer, regardless of wealth levels.
SourceUniversity of California - Riverside·JournalJAMA Network Open·TypeData/statistical analysis·DateApr 15, 2022
A new study published in the Chinese Medical Journal assessed mortality risk in middle-aged and older Chinese individuals with multiple diseases. The study identified four multimorbidity patterns, with cardiometabolic being the most common, and found that individuals with these patterns had a significantly increased mortality risk.
SourceCactus Communications·JournalChinese Medical Journal·TypeObservational study·DateApr 13, 2022
Children of exceptionally long-lived parents and their spouses experience lower risk of type II diabetes compared to the general population. The study found that low BMI, high HDL cholesterol, and certain hormones in the blood protect against developing diabetes II.
SourceFrontiers·JournalFrontiers in Clinical Diabetes and Healthcare·TypeObservational study·DateApr 11, 2022
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
A study of 3,900 older adults found factors associated with decreased physical activity include older age, living alone, obesity, adverse health conditions, and poor physical functioning. The results highlight the need for interventions targeting these barriers to promote healthy lifestyles in older age.
SourceJAMA Network·JournalJAMA Network Open·DateApr 7, 2022
Researchers created brain charts spanning human lifespan, revealing rapid brain growth in early life and slow decline with age. The charts use aggregated MRI datasets, covering a range of ages from fetus to 100-year-old adult, and aim to create a common language for describing brain development and maturation.
SourceUniversity of Cambridge·JournalNature·TypeComputational simulation/modeling·DateApr 6, 2022
The BrainChart platform benchmarks brain development based on MRI data from over 100,000 individuals, creating a standardized chart like those for height and weight. The tool identifies previously unreported neurodevelopmental milestones and provides a common language to understand brain images from different sources.
SourceChildren's Hospital of Philadelphia·JournalNature·DateApr 6, 2022
A recent study found that the C/EBPβ/AEP pathway accelerates Alzheimer's disease progression and shortens lifespan. In contrast, deleting this gene or inhibiting AEP increases life expectancy in mice and worms.
SourceChinese Academy of Sciences Headquarters·JournalScience Advances·DateMar 31, 2022
A study led by Max Planck researchers found that parrots with large relative brain sizes have longer lifespans, averaging up to 30 years. This suggests that increased cognitive ability may help parrots navigate threats and enjoy longer lives.
SourceMax-Planck-Gesellschaft·JournalProceedings of the Royal Society B Biological Sciences·TypeMeta-analysis·DateMar 29, 2022
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
A systematic review and meta-analysis of 26 studies found music interventions to be associated with clinically meaningful improvements in health-related quality of life. The study suggests that music-making and listening may have a positive impact on overall well-being, particularly for individuals with health conditions.
SourceJAMA Network·JournalJAMA Network Open·DateMar 22, 2022
Researchers at Pusan National University have developed oxidation-resistant copper thin films, which could potentially replace gold in semiconductor devices. The films' flat surface reduces the growth of copper oxides on its surface, making them resistant to corrosion.
SourcePusan National University·JournalNature·TypeExperimental study·DateMar 21, 2022
Researchers at University of Cologne discovered that specific diets can safeguard against acute kidney injury in mouse models. The six tested diets showed overlapping changes in cysteine catabolism as a potential mechanism for organ protection.
SourceUniversity of Cologne·JournalTranslational Research·TypeExperimental study·DateMar 21, 2022
A new study by researchers in Ontario found that pandemic-related slowdowns of cancer surgeries resulted in 843 life-years lost across the province's cancer population. The study highlights the need for measures of surgical prioritization during pandemic-related slowdowns.
SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·TypeComputational simulation/modeling·DateMar 21, 2022
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
A new study published in PLOS Medicine found that the number of healthy years a person lives is increasing even for those with common chronic conditions. However, men and women with cognitive impairment experienced a decrease in disability-free life expectancy.
SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateMar 15, 2022
A study in rural Ethiopia found that community-based rehabilitation, supported by local health centers and medication, reduced symptoms and improved functioning for individuals with schizophrenia. Community-based rehabilitation workers also helped participants access healthcare services and support their families.
SourceUniversity of Nottingham·JournalThe Lancet Global Health·TypeRandomized controlled/clinical trial·DateMar 15, 2022
A study published in Nature Metabolism found that body temperature has a greater impact on lifespan than metabolic rate, contrary to the traditional 'live fast, die young' phrase. The researchers used an unusual experiment where high temperatures increased lifespan by lowering metabolism and reducing body temperature.
SourceChinese Academy of Sciences Headquarters·JournalNature Metabolism·DateMar 14, 2022
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers found that GlyNAC supplementation can increase lifespan and improve multiple key age-associated defects in mice. The supplement corrected glutathione deficiency, oxidative stress, mitochondrial dysfunction, and other hallmarks of aging.
SourceBaylor College of Medicine·JournalNutrients·TypeExperimental study·DateMar 7, 2022
A longitudinal study confirmed that adults' religious styles change over a person's lifetime, with most participants moving to a higher style. Factors such as openness to experience and low agreement with their own religion supported this progression, while regression was also observed in a significant number of cases.
Researchers have developed a new model system using Daphnia to study aging, focusing on interventions that extend active life and health rather than just lifespan. This approach addresses existing problems in the field, such as lack of standardized data and misinterpretation of results.
SourceHarvard Medical School·JournalAging Cell·DateFeb 28, 2022