The Human Brain Project unveiled its 8th annual Summit with presentations of new scientific insights and technologies. The project has developed a powerful new infrastructure called EBRAINS, which will serve generations of brain scientists.
Brain activity during wakefulness presents large integrated and dynamic network modules, which tend to vanish or fragment during sleep or under general anesthesia. The researchers built artificial time-evolving networks to test and benchmark algorithms for detecting these structures.
SourceAmerican Institute of Physics·JournalChaos An Interdisciplinary Journal of Nonlinear Science·DateSep 21, 2021
Researchers found that subjects' heart rates synchronized even when listening to a story alone, as long as they were paying attention. This synchronization was predictive of conscious processing of the narrative, and had implications for understanding mindfulness and the brain-body connection.
SourceCell Press·JournalCell Reports·TypeExperimental study·DateSep 14, 2021
The RIT workshop series on sustainable computing aims to create computers with environmental consciousness from raw materials to recycling. Keynote speakers will discuss trends in computing and its environmental footprint.
SourceRochester Institute of Technology·DateSep 9, 2021
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A synthetic hinge concept developed by Indiana University School of Medicine Professor Michael A. Weiss and his team could lead to a breakthrough in 'smart' insulin therapy. The invention exploits a natural mechanism that allows the insulin to adjust its activity based on blood glucose levels, which could transform diabetes care.
SourceIndiana University School of Medicine·JournalProceedings of the National Academy of Sciences·DateAug 2, 2021
A recent study published in PLOS ONE explores the experience of pure consciousness during meditation, identifying 12 key factors that characterize this state. These findings provide insight into human consciousness and have implications for further research, including potential applications beyond meditation practices.
SourceJohannes Gutenberg Universitaet Mainz·JournalPLOS ONE·DateJul 21, 2021
Seiichi Shirai's practice of calligraphy was characterized by four aspects: interest in kanji's primitive aspects, emphasis on utility, asceticism, and rapid writing. His calligraphy reflected the universal potential of objects without being misled by external form or origin.
SourceShinshu University·JournalJapan Architectural Review·DateJun 17, 2021
A team of researchers studied how the brain recovers from general anesthesia, finding that recovery unfolds over time and higher cognition recovers first. After anesthetizing 30 healthy adults for three hours, they discovered that abstract problem-solving abilities return before reaction time and attention.
SourceMichigan Medicine - University of Michigan·DateMay 27, 2021
A study published in Neurology found that nearly half of people with a history of concussion with loss of consciousness are living with disability. The areas with the greatest amount of disability were mobility and general physical activities, affecting 38% and 36% of participants respectively
SourceAmerican Academy of Neurology·JournalNeurology·DateMay 26, 2021
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Researchers developed AI algorithms that assess unconsciousness in patients based on brain activity with high accuracy and reliability. The algorithms outperformed existing methods in real-world testing, distinguishing between conscious and unconscious states in surgery patients.
SourcePicower Institute at MIT·JournalPLOS ONE·DateMay 7, 2021
A new study from Michigan Medicine researchers identifies the anterior insular cortex as a key area in the brain that acts as a filter, allowing only the most important sensory information to enter conscious awareness. This gate-like structure regulates brain network transitions and plays a crucial role in conscious access.
SourceMichigan Medicine - University of Michigan·JournalCell Reports·DateMay 4, 2021
A new paper by Kyoto University researchers highlights the ethical implications of brain organoid research, which could lead to breakthroughs in treating diseases like dementia or schizophrenia. However, transplanting brain organoids raises concerns about consciousness, morality, and potential risks to patients.
SourceKyoto University·JournalAJOB Neuroscience·DateApr 7, 2021
Scientists developed a new method to understand how the brain builds associations between previously unrelated words. By measuring brain responses to incongruent sentence endings, researchers found that the brain learns new associations rapidly and independently of behavioral responses.
SourceUral Federal University·JournalJournal of Neurolinguistics·DateMar 31, 2021
Researchers used machine learning to analyze brain activity in monkeys and found that complexity is key to indicating consciousness, shifting the focus from frontal cortex to back of the head for electrode placement.
SourceUniversity of Wisconsin-Madison·JournalCell Systems·DateMar 16, 2021
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A team of researchers has identified a functional 'rich club' of brain regions that orchestrate the global workspace, a concept proposed by psychologist Bernard Baars in 1988. The study, published in Nature Human Behavior, used fMRI data from over 1,000 participants to reveal unique brain regions coordinating information from various s...
A brain network comprising thalamus, cingulate cortex, and angular gyri is associated with changes in connectedness during sleep and anesthesia. This region's activity corresponds to changes in conscious state, indicating its possible role in human consciousness.
A small study of adults with major depression found that two doses of psilocybin, given with supportive psychotherapy, produced rapid and large reductions in depressive symptoms. Most participants showed improvement and half achieved remission after a four-week follow-up.
SourceJohns Hopkins Medicine·JournalJAMA Psychiatry·DateNov 4, 2020
Researchers Jussi Lindgren and Jukka Liukkonen propose an objective interpretation of quantum mechanics that eliminates the role of consciousness in measuring outcomes. Their study suggests a fixed correlation between location and momentum, implying reality is independent of measurement.
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A two-stage model integrates continuous processing with discrete conscious moments, resolving the 1,500-year-old question of whether consciousness is continuous or discrete. This new framework offers a fresh perspective on information processing and could revolutionize fields like neuroscience, psychology, and computer vision.
SourceCell Press·JournalTrends in Cognitive Sciences·DateSep 3, 2020
Researchers propose a new model explaining how consciousness arises, suggesting that the brain processes and integrates information for up to half a second before becoming aware of it. This counterintuitive view challenges the idea of continuous perception and provides insights into how people experience reality.
SourceEcole Polytechnique Fédérale de Lausanne·JournalTrends in Cognitive Sciences·DateSep 3, 2020
Leading coma experts have created a three-part plan to improve patient care and deepen understanding of coma and other conditions. The plan includes better classification of coma types, development of biomarkers to predict prognosis, and clinical trials for new therapies to promote recovery of consciousness.
SourceUniversity of Virginia Health System·JournalNeurocritical Care·DateAug 19, 2020
Researchers developed a computational model to analyze brain activity in different states of consciousness, from wakefulness to deep sleep. The study found that the brain's functional segregation into systems with distinct activation patterns during cognition.
SourceUniversitat Pompeu Fabra - Barcelona·JournalNeuroImage·DateJun 30, 2020
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Researchers at Johns Hopkins Medicine found that psilocybin reduces neural activity in the claustrum by 15% to 30%, associated with stronger subjective effects. The study also showed changes in how the claustrum communicates with other brain regions involved in hearing, attention, and memory.
SourceJohns Hopkins Medicine·JournalNeuroImage·DateJun 5, 2020
Researchers at Scripps Research Institute discover that anesthetics trigger brain loss of consciousness by perturbing lipid clusters in the cell membrane, leading to changes in consciousness. This breakthrough solves a century-old scientific debate and opens up new avenues for understanding brain functions.
SourceScripps Research Institute·JournalProceedings of the National Academy of Sciences·DateMay 29, 2020
Researchers at the Weizmann Institute created a simple 'sniff test' that accurately predicts which brain-injured patients will regain consciousness. The test, which measures nasal airflow patterns in response to odors, showed 92% accuracy in predicting patient survival for at least three years.
SourceWeizmann Institute of Science·JournalNature·DateMay 21, 2020
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The claustrum is a key structure in coordinating brain activity across multiple senses and areas. Researchers found that slow-wave brain activity, characteristic of sleep states, is controlled by the claustrum.
Using integrated information theory, researchers from the University of Tsukuba studied schools of Plecoglossus altivelis fish and found a discontinuity between three- and four-fish schools. The study revealed that leadership emerges in larger groups, improving understanding of collective behavior dynamics.
SourceUniversity of Tsukuba·JournalPLOS ONE·DateMay 7, 2020
A new study published in Nature found that a simple 'sniff test' can accurately diagnose and predict the recovery of severely brain-injured patients. The test measures the response to different smells, with minimally conscious patients showing significant changes in breathing patterns.
SourceUniversity of Cambridge·JournalNature·DateApr 29, 2020
Research finds that the dorsal attention network (DAT) and default-mode network (DMN) are anti-correlated, with suppressed activity during unconscious states. The study uses fMRI data to uncover temporal circuits of brain activity supporting human consciousness.
SourceMichigan Medicine - University of Michigan·JournalScience Advances·DateMar 11, 2020
A study published in Neuron found that stimulating the central lateral thalamus with low current and specific frequency can revive monkeys from deep anesthesia. Researchers believe this could lead to new treatments for brain disorders such as coma and spatial neglect.
SourceUniversity of Wisconsin-Madison·JournalNeuron·DateFeb 14, 2020
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A team of researchers has made a significant discovery about the neural mechanisms of consciousness. By stimulating the central lateral thalamus in macaques under anesthesia, they were able to wake the animals and elicit normal waking behaviors. This breakthrough sheds light on the specific area of the brain responsible for consciousness.
Researchers used rats to demonstrate that EEG doesn't always track with being awake, raising questions about interpreting EEG data in medical decisions. The study suggests certain EEG features may not accurately capture consciousness levels, but still have value in detecting unconsciousness.
SourceMichigan Medicine - University of Michigan·DateDec 23, 2019
The study identifies three dimensions of meaning in the brain: language, reference to self or external source, and social constructs. The researchers used functional MRI scans to analyze neural activation patterns for individual abstract concepts across participants.
SourceCarnegie Mellon University·JournalCerebral Cortex·DateOct 29, 2019
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A new theory suggests that consciousness arises from synchronized neural activity and is guided by thermodynamic principles. During conscious states, the brain has higher entropy and more connected neural networks, leading to greater mental flexibility.
SourceNovela Neurotech·JournalFrontiers in Neuroscience·DateOct 25, 2019
A new study is using advanced brain imaging and non-invasive brain stimulation to help patients with prolonged disorders of consciousness. The RAINDROP trial aims to improve communication and recovery rates for these patients, who remain trapped in their unresponsive bodies despite retaining higher levels of awareness.
A new study published in Neurology provides unprecedented insights into brain connections disrupted in comatose patients. Researchers used advanced MRI techniques to image brain pathways connecting the brainstem to the thalamus and hypothalamus, revealing disruption in specific neuronal pathways associated with consciousness.
SourceMassachusetts General Hospital·JournalNeurology·DateSep 4, 2019
Experts like Lincoln Taiz conclude that plants don't possess the threshold brain structure for consciousness. They argue that plants' responses to stimuli are genetically encoded and not indicative of intentional choice or learning.
SourceCell Press·JournalTrends in Plant Science·DateJul 3, 2019
A study published in the New England Journal of Medicine found that nearly 1 in 7 brain-injured ICU patients show evidence of hidden consciousness just days after injury. Patients with such signs are more likely to recover, according to researchers at Columbia University and NewYork-Presbyterian. The technique used to detect hidden con...
SourceColumbia University Irving Medical Center·JournalNew England Journal of Medicine·DateJun 26, 2019
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Researchers at Columbia's Data Science Institute used cellular resolution imaging to investigate changes in neuronal microstates during anesthesia. They found that anesthesia disrupts local network dynamics, leading to breakdowns in macroscale connectivity.
SourceData Science Institute at Columbia·JournalCell Systems·DateMay 1, 2019
A new study found that having Black female role models in STEM is crucial for black women college students to feel a sense of belonging. The research, led by Indiana University-Purdue University Indianapolis School of Science, also discovered that seeing a Black male scientist can signal more belonging, while high stigma consciousness ...
SourceIndiana University-Purdue University Indianapolis School of Science·JournalPsychology of Women Quarterly·DateApr 16, 2019
A study found that consciousness is characterized by a complex configuration of interareal coordination, deviating from anatomical connections. In contrast, unconscious states are marked by positive patterns of interareal coherence dominated by brain region anatomy. The researchers suggest that transient brain signal coordination patte...
SourceUniversitat Pompeu Fabra - Barcelona·JournalScience Advances·DateFeb 12, 2019
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Scientists have identified four distinct brain pattern profiles associated with conscious and unconscious states, shedding light on the neural dynamics underlying human consciousness. The findings hold potential for developing reliable biomarkers of consciousness and externally induced manipulations to restore awareness.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience Advances·DateFeb 6, 2019
A study published in Current Biology found that participants could reactivate associations formed between foreign words and their translations during a midday nap. The brain's active states supported the retrieval of these sleep-formed associations, suggesting that learning can occur independently of consciousness.
SourceUniversity of Bern·JournalCurrent Biology·DateJan 31, 2019
Researchers found that even extensive thalamus damage does not severely impair consciousness, challenging decades-old medical dogma. The study identifies a new pathway from the brainstem through the hypothalamus and basal forebrain into the cortex as critical for maintaining wakefulness.
SourceUniversity of Iowa Health Care·JournalAnnals of Neurology·DateNov 28, 2018
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Finnish research reveals that bodily sensations play a crucial role in shaping conscious feelings, with emotions influencing both physical and mental states. The study identifies five major categories of subjective feelings, including positive emotions, negative emotions, cognitive functions, somatic states, and illnesses.
SourceUniversity of Turku·JournalProceedings of the National Academy of Sciences·DateAug 31, 2018
A new guideline provides recommendations for improving diagnosis, health outcomes, and care of people with prolonged disorders of consciousness. The guideline emphasizes the importance of early and accurate diagnosis to avoid misdiagnosis and premature treatment withdrawal.
SourceAmerican Academy of Neurology·JournalNeurology·DateAug 8, 2018
A novel study by Michigan Medicine researchers suggests that the prefrontal cortex has a crucial switchboard-like relationship with other brain areas, helping to ignite awareness of visual information. This finding could lead to new approaches in treating individuals with disorders of consciousness, such as coma or vegetative states.
SourceMichigan Medicine - University of Michigan·JournalCurrent Biology·DateJun 21, 2018
Researchers recorded neuronal activity in patients with epilepsy using implanted electrodes, revealing that frontal lobe neurons change before a new conscious experience emerges and that medial temporal lobe neurons change one second prior to perception. This study sheds light on the origin of consciousness.
SourceAmerican Friends of Tel Aviv University·JournalNature Communications·DateJun 13, 2018
A study of over 350,000 US veterans found that even mild traumatic brain injuries (TBI) without a loss of consciousness were associated with increased dementia risk. The risk was also elevated for patients with moderate to severe TBIs.
SourceJAMA Network·JournalJAMA Neurology·DateMay 7, 2018
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Researchers tracked over 350,000 veterans and found a significant link between concussion and dementia, with concussion alone doubling the risk. The study suggests that traumatic brain injury may hasten neurodegenerative conditions by inducing or accelerating abnormal protein accumulation.
SourceUniversity of California - San Francisco·JournalJAMA Neurology·DateMay 7, 2018
A large population of U.S. veterans with mild, moderate, or severe traumatic brain injury were found to have a higher risk of developing Parkinson's disease. Those with mild traumatic brain injury had a 56% increased risk, while those with moderate to severe injuries had an 83% and 71% increased risk respectively.
SourceAmerican Academy of Neurology·JournalNeurology·DateApr 18, 2018
Researchers at New York University have found that strong signals can be transmitted across many areas of the brain using a balanced large-scale neural circuit mechanism. This discovery may help explain how conscious information processing is achieved.
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Studies analyzing brain activity during sedation, surgical anesthesia, and vegetative states reveal fragmented networks and decreased information integration. Researchers hope to develop better methods for quantifying anesthesia depth and assessing consciousness in patients.
SourceMichigan Medicine - University of Michigan·JournalTrends in Neurosciences·DateFeb 28, 2018
Research reveals sleepwalkers have improved automation in movement control compared to non-sleepwalkers. They maintain speed and accuracy during tasks requiring conscious attention, indicating potential daytime markers for sleepwalking diagnosis.
SourceEcole Polytechnique Fédérale de Lausanne·JournalCurrent Biology·DateOct 23, 2017
Researchers successfully restored consciousness in a 35-year-old man who had been in a vegetative state for 15 years after implanting a vagus nerve stimulator. The study reveals major changes in brain activity and connectivity, suggesting that right intervention can yield changes in consciousness even in severe clinical cases.
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Researchers found that neurons fire in both cases of noticing and non-noticing, but differently, supporting a nuanced view of consciousness. The study used brain electrodes to record individual neuron activity in awake patients.
A mathematical model of embodied consciousness predicts states of consciousness and behavior, analyzing free energy and projective geometry. The model, developed by an international team of experts, has potential industrial applications in robotics, AI, and healthcare.
SourceUniversité de Genève·JournalJournal of Theoretical Biology·DateAug 16, 2017
Researchers identify critical level at which unconscious information becomes conscious, revealing shared underlying mechanisms with simpler decisions. The study offers new hope for understanding the biological foundations of consciousness.
SourceThe Zuckerman Institute at Columbia University·JournalCurrent Biology·DateJul 27, 2017
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A Massachusetts General Hospital study found that fMRI and EEG can identify covert consciousness in ICU patients, allowing families to make informed decisions about care. The tests detected activity in higher-order cortex areas of the brain, which could have implications for patient recovery.
SourceMassachusetts General Hospital·JournalBrain·DateJul 20, 2017
A study from the University of Waterloo found that just 10 minutes of daily meditation can help prevent mind wandering and repetitive, anxious thoughts. This mindfulness training may have protective effects on mind wandering for anxious individuals.
SourceUniversity of Waterloo·JournalConsciousness and Cognition·DateMay 1, 2017