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Science News Archive September 2011 - Page 26


Page 26 of 29

Virtual reality may help adults recover from stroke

Early results suggest that virtual reality (VR) human-computer interfaces can improve arm function and daily activities in adult stroke patients compared to traditional therapy. VR training has been found to have positive effects on these outcomes, but more data is needed to assess the long-lasting benefits of this approach.

SourceWiley·JournalCochrane Database of Systematic Reviews·DateSep 6, 2011

Researchers identify new drug target that stimulates

JDRF-funded researchers identify a protein and chemical compound that stimulate beta cell growth, providing a new drug target for diabetes treatment. The discovery may lead to the development of tests to measure beta cell number using Tmem27 fragments as a biomarker.

SourceJDRF·JournalCell Metabolism·DateSep 6, 2011

Pain relief can now be based on solid evidence

A Cochrane Review analyzed 35 Cochrane Reviews of randomized trials to evaluate the effectiveness of 46 different drug/dose combinations against acute pain. The review found that no single drug provides high levels of pain relief for all patients, but some options have a solid evidence base

SourceWiley·JournalCochrane Database of Systematic Reviews·DateSep 6, 2011

Recycling fat might help worms live longer

Researchers found that increased autophagy in germline-less worms led to higher activity of a fat-digesting enzyme, extending their lifespan. The study suggests that recycling fat is beneficial for worms, and may have implications for human diseases such as cancer and Alzheimer's.

SourceSanford Burnham Prebys·JournalCurrent Biology·DateSep 6, 2011

Prenatal exposure to phthalates linked to decreased mental and motor development

A new study found that prenatal exposure to phthalates is associated with decreased mental and motor development in preschoolers, as well as increased behavioral problems. The researchers measured metabolites of four phthalates in maternal urine and evaluated associations between prenatal exposures and child development at age 3.

SourceColumbia University's Mailman School of Public Health·JournalEnvironmental Health Perspectives·DateSep 6, 2011

Circadian clocks in a blind fish

Researchers found that a species of cavefish, Phreatichthys andruzzii, has an unusual circadian clock that ticks at an extremely long period, unaffected by eye loss. The study suggests that the fish's clocks can be regulated by feeding behaviour, but not light exposure.

SourcePLOS·JournalPLOS Biology·DateSep 6, 2011

Violence remains in top 10 causes of death

The National Center for Injury Prevention and Control and the American Journal of Lifestyle Medicine have developed a special issue to examine violence prevention. The issue highlights the complexities of violence and its deep impact on society, with significant monetary effects estimated at over $70 billion annually.

SourceSAGE·JournalAmerican Journal of Lifestyle Medicine·DateSep 6, 2011

Major advance in sleeping sickness drug made by Glasgow scientists

Researchers at the University of Glasgow have created a safer oral version of the sleeping sickness drug melarsoprol, increasing its solubility and releasing it slowly in the gut. The new treatment retained its ability to kill the infection and cured mice infected with the parasite after a seven-day daily dosing schedule.

SourcePLOS·JournalPLOS Neglected Tropical Diseases·DateSep 6, 2011

'White-coat effect' elevates greyhounds' blood pressure

A new study has found that retired racing greyhounds' blood pressure increases significantly when taken to a veterinary clinic, but returns to normal at home. The 'white-coat effect' was observed in 22 greyhounds, with systolic pressures averaging 30 points higher in the hospital than at home.

SourceOhio State University·JournalJournal of Veterinary Internal Medicine·DateSep 6, 2011

Stomach bacterium damages human DNA

Research reveals that Helicobacter pylori causes DNA breaks in gastric mucosa cells, triggering genetic mutations and cell death. The study's findings suggest that prolonged infections can lead to exhaustion of the cell's repair response, exacerbating gastric carcinogenesis.

SourceUniversity of Zurich·JournalProceedings of the National Academy of Sciences·DateSep 5, 2011

Key protein reveals secret of stem cell pluripotency

Researchers identified a protein that helps maintain mouse stem cell pluripotency by activating signal pathways via CC chemokine ligand 2 (CCL2). This finding offers insights into cultivating human iPS/ES cells without feeder cells, reducing the risk of contamination and health risks.

SourceRIKEN·JournalStem Cells·DateSep 5, 2011

Ancient humans were mixing it up

A team of researchers led by Michael Hammer found evidence of hybridization between modern humans and archaic forms in Africa. Contemporary African populations contain small proportions of genetic material brought in by an archaic population that split from the ancestors of anatomically modern humans about 700,000 years ago.

SourceUniversity of Arizona·JournalProceedings of the National Academy of Sciences·DateSep 5, 2011

Even mild cognitive impairment appears to substantially increase risk for death

A long-term study found that even mild cognitive impairment substantially increases the risk of death, with a strong impact comparable to other chronic diseases. The study, which followed nearly 4,000 patients over 13 years, suggests that recognition of cognitive impairment in primary care practices should be given higher priority.

SourceIndiana University School of Medicine·JournalAnnals of Internal Medicine·DateSep 5, 2011

Male-female ring finger proportions tied to sex hormones in embryo; may offer health insights

Biologists found that male and female digit proportions are determined by the balance of sex hormones during early embryonic development. The study provides a genetic explanation for links between finger proportions and traits such as sperm counts, aggression, and health problems like autism and breast cancer.

SourceUniversity of Florida·JournalProceedings of the National Academy of Sciences·DateSep 5, 2011

Novel method for increasing antibiotic yields

Researchers have identified a system for targeted amplification of gene clusters in bacteria, which can significantly increase the production of antibiotics. This discovery has the potential to revolutionize the commercial production of antibiotics and may also uncover new, undiscovered antibiotics.

SourceNorwich BioScience Institutes·JournalProceedings of the National Academy of Sciences·DateSep 5, 2011

The search for predictors of risk for PTSD

A study found a link between a serotonin transporter gene variant and PTSD risk, suggesting the gene may predict symptom development after trauma. The researchers also discovered that this gene is associated with depression following life stress, highlighting its potential role in mental health.

Crowd-sourcing the E. coli O104:H4 outbreak

Crowd-sourcing efforts identified key disease-causing genes in the E. coli O104:H4 strain, which carries a high number of genes involved in disease. The outbreak, affecting over 16 countries, has been linked to contaminated beansprouts and resulted in thousands of cases and multiple deaths.

New mutations in leukemia: Researchers found mechanism that can help design future therapies

A group of mutations in the interleukin-7 receptor gene have been identified in T-cell acute lymphoblastic leukemia patients, leading to uncontrolled cell proliferation. Researchers found that certain pharmaceutical drugs already in clinical use can eliminate these cells, providing a potential therapeutic approach against leukemia.

SourceInstituto de Medicina Molecular·JournalNature Genetics·DateSep 4, 2011