Researchers found that firms with stronger positions in supply chains provide more trade credit to customers, while those with weaker positions receive less. This contradicts the financing advantage theory and supports the recursive moral hazard theory of trade credit.
Panayiotis 'Panos' Diplas, a Lehigh University professor, has been awarded the 2021 Hunter Rouse Hydraulic Engineering Award for his fundamental contributions to turbulence in sediment transport and ecohydraulics. The award is presented by ASCE's Environmental and Water Resources Institute.
Researchers have discovered that depleting macrophages in tumors activates tumor-specific cytotoxic T cells, eliminating large, RT-resistant colorectal and pancreatic cancers. SIRPalpha-depletion transforms the tumor microenvironment into a potent tumoricidal niche.
Researchers from the University of Tsukuba have demonstrated the direct conversion of scar tissue cells to heart muscle cells in mice after a heart attack. This breakthrough finding suggests that fibroblasts can be directly reprogrammed into cardiomyocytes, potentially preventing heart failure and death.
A new study suggests that using a brain-training app can help people reduce their junk food consumption and lose weight. The app trains users to associate healthy foods with stopping and unhealthy snacks with avoiding, resulting in an average weight loss of half a kilogram and a small increase in healthy food eaten.
A study published in the Journal of Comparative Economics found that bribery in public healthcare not only fails to improve services but also exacerbates health problems and reduces nutrition quality. Post-communist countries, including Russia, reported high rates of corruption, with many patients experiencing bribes for medical services.
Researchers found that elephants can store up to nine liters of water by dilating their nostrils, allowing them to suck up three liters per second. This unique ability has inspired the development of more efficient robots using air motion, and may also help conservation efforts for endangered elephant species.
A Mendelian randomization study found no evidence that vitamin D levels are associated with reduced COVID-19 susceptibility, hospitalization, or severe disease outcomes. The study's results suggest that raising circulating vitamin D levels through supplementation may not improve COVID-19 outcomes in the general population.
Researchers used environmental DNA (eDNA) to detect the presence of invasive New Zealand mud snails in waters they inhabited incognito, revealing a new population in central Pennsylvania. The eDNA technique allowed for early detection of the snail's invasion, even when traditional methods would not have found them.
Researchers at Tokyo Institute of Technology develop a 3D functional interposer containing an embedded capacitor, saving up to 50% package area and reducing wiring resistance. This compact design enables less noise and power consumption, paving the way for new semiconductor package structures with greater miniaturization.
Researchers have found that targeting the FK506-binding protein 51 (FKBP51) promotes autophagy and reduces toxic Huntingtin protein levels, potentially providing a new treatment option for Huntington's disease. This new mechanism avoids worrisome side effects associated with rapamycin.
Researchers found that training health workers to promote healthy feeding practices in pregnant women resulted in children consuming less fat and carbohydrates at 3 years of age and having lower measures of body fat at 6 years. The study suggests that early intervention can have a significant impact on childhood obesity risk.
Researchers developed a robotic mechanism for picking and trimming button mushrooms, achieving a 90% success rate in initial tests. The system's performance was improved after multiple picks, demonstrating its potential for automated harvesting.
A new study suggests a return-on-investment approach to focus taxonomic research on species in need of conservation. Researchers used this method to identify 24 Australian lizard and snake species that require better classification, highlighting the critical importance of accurate taxonomy for effective conservation.
Scientists have created a miniature 3D bone marrow model that can predict patient responses to Eltrombopag therapy for platelet disorders. The model uses silk protein scaffolding and patient-derived cells to recreate human bone marrow conditions.
The Treatabolome project is an EU initiative that seeks to deliver rare disease and gene-specific treatment information to healthcare professionals. Systematic reviews on various rare neurological disorders are now available, providing a foundation for the platform's database.
Researchers have discovered a potential way to prevent Ewing sarcoma tumours from spreading by understanding how they develop a protective shield against the harsh environment of the bloodstream. This breakthrough may lead to the development of a clinical-grade immunotherapeutic treatment for Ewing sarcoma.
A recent review in Genome Biology and Evolution discusses the evolutionary fates of supergenes, revealing new findings that challenge classical models. The genomic architecture of a supergene is inextricably tied to its evolutionary fate, with empirical studies yielding surprises about their origin and genetic architecture.
Researchers developed a novel solar energy-driven method to produce ethylene glycol (EG) from methanol, offering a sustainable and clean alternative. The catalyst, nitrogen-doped tantalum oxide, demonstrated high activity and stability for EG production, making it an environmentally friendly candidate for industrial applications.
A UCI-led study has identified key molecular mechanisms underlying complex traits and diseases, providing new insights into the role of genetic variation and environmental factors. The research reveals that specific molecular features associated with phenotypic variations contribute substantially to disease risk.
Researchers found that transgenic mice with high levels of SIRT6 gene exhibit increased life expectancy and vigor, without frailty. The mechanism reveals enhanced energy generation capacity, facilitating healthy aging, and could lead to human lifespan prolongation methods.
Researchers have identified 'pocket factors' as new therapeutic targets for flaviviruses, including dengue virus. The chimeric viruses mimic infectious particles with unprecedented detail, providing a universal path to structure determination and potential vaccines or diagnostic tools.
Volunteers in a Central Oregon bat survey detected 25 Euderma maculatum bats in a 24,000-square-kilometer area, filling gaps in basic information about species abundance and distribution. The study's design suggests its potential for scaling up to larger areas, aiding conservation efforts.
A new study from the University of Kansas reveals that people flocked to Parler to discuss COVID-19 vaccines in an echo chamber-type environment, where they shared misinformation and reinforced conspiracy theories. The analysis shows that users followed themes and used hashtags to spread their content, highlighting the importance of ad...
Electrical engineers at UC San Diego developed a technology that converts low-resolution light to high-resolution light, enabling ordinary microscopes to image living cells with a resolution of up to 40 nanometers. The technology uses a specially engineered material that shortens the wavelength of light as it illuminates the sample.
A Phase 1/2 clinical trial has begun at the NIH to assess the safety and immunogenicity of different COVID-19 vaccine booster regimens. Participants will receive a single booster dose of the Moderna COVID-19 vaccine, followed by telephone check-ins and in-person follow-up visits for one year.
Researchers successfully created amorphous ice similar to interstellar space and on Jupiter's moon Europa, which could help interpret data from future NASA missions. They also developed an envelope system that diverts heat away from buildings and stores it for future use, reducing energy consumption by over 50%. Additionally, scientist...
A recent study on TB outbreak in an Irish prison highlights the need for increased testing and improved care. The study found that 50% of staff may have developed latent TB as a result of occupational exposure, posing a risk of progression to active TB.
Researchers found a connection between high inequality in subsistence societies and increased blood pressure, as well as respiratory diseases like pneumonia. However, chronic conditions like hypertension and cardiovascular disease were less prevalent in these communities.
Researchers at Tel Aviv University found that sick bats isolate themselves to prevent the spread of contagious diseases. By staying away from their colonies, bats conserve energy and reduce the likelihood of pathogens being transmitted to humans, suggesting a potential natural defense mechanism.
Researchers have developed an antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus, a highly lethal tick-borne disease. The therapy, called DVD-121-801, overcomes infection in mice with just one dose administered after virus exposure.
Researchers at University at Buffalo are working on ways to improve the WIC shopping experience, making it easier for customers to find eligible products and navigate checkout processes. The team has identified several key barriers, including restrictions on foods, identifying product sizes and types, and poor staff training.
Moffitt Cancer Center experts present phase 2 results from several clinical studies evaluating the efficacy of CAR T-cell therapy, ixazomib maintenance therapy, and immunotherapies for various types of cancer, including acute lymphoblastic leukemia, multiple myeloma, prostate cancer, and triple-negative breast cancer.
Scientists at the Cluster of Excellence ct.qmat have successfully created non-Hermitian topological states in topolectric circuits, exhibiting stable and robust features. This breakthrough has far-reaching implications for future quantum technologies and may establish a milestone towards developing light-controlled computers.
Researchers have discovered a new mechanism in magnetic compounds that couples multiple topological bands, significantly enhancing the effects of quantum phenomena. The coupling leads to an anomalous Hall effect, where spontaneous symmetry breaking causes a transverse acceleration of electron currents.
Researchers developed a non-Markov chain algorithm in a 2D mica-based RRAM device, exhibiting high on/off ratio and retention time. The device utilizes controllable ion transport to realize a multi-path non-Markov chain.
Researchers used structural brain imaging to detect developmental effects of linguistic and cognitive stimulation on infant brains. They found that high-quality educational experiences in early childhood were associated with increased brain size, particularly in males.