Researchers found that regular cycles of a fasting-mimicking diet in mice helped counteract the negative effects of a high-fat, high-calorie diet. The study suggests that this diet may have potential as 'medicine' to prevent obesity and heart disease.
A HKUST research team found a nearly doubled Diatom/Dino ratio in the Pearl River Estuary over two decades, challenging the notion that higher ratios indicate better water quality. The study also reveals temperature and nutrient concentration play significant roles in diatom blooms.
Researchers identified a wide divergence of sex chromosomes in jojoba plants, which could lead to the development of a DNA test to identify male and female plants. The study reveals that male and female jojoba plants have diverged genetically due to environmental stress, with differing reproductive resource allocation requirements.
A large population-based cohort study found that combined oral contraceptives reduce the risk of type 2 diabetes and pre-diabetes in women with PCOS by 26%. Women with PCOS have twice the risk of developing type 2 diabetes or pre-diabetes, highlighting the need for treatments to reduce this risk.
Researchers found that tuning the interface and twist angle of layered 2D materials enhances key properties, leading to stronger interlayer coupling and improved electronic and optical device performance. This discovery has great importance for various applications in optoelectronics, electronics, batteries, lighting, and appliances.
A retrospective study demonstrates that AI-powered Fabric GEM algorithm can detect over 90% of disease-causing variants in infants with rare diseases using whole-genome and whole-exome data. The algorithm also ranks specific genes associated with these variants, assisting clinicians in diagnosis.
Researchers at the University of Oklahoma have contributed to a study on a new antibiotic that may cure Lyme disease and eradicate its occurrence from the environment. The antibiotic, hygromycin A, targets the ribosomes of the bacteria Borrelia burgdorferi and shows promise in treating the disease.
Scientists from Stellenbosch University found that phytoplankton are active during winter in the Southern Ocean, contradicting previous assumptions. This discovery improves predictive global climate models and sheds light on adaptation strategies of phytoplankton under adverse growth conditions.
Scientists have found that adding a single atom to rutile titanium dioxide can create oxygen vacancies, leading to more stable local structures and controlling reaction stability. This discovery could lead to new ways of understanding the relationship between material structure and function.
A review by Washington University and Duke experts exposes mass incarceration's harm on families, particularly low-income communities of color. Family member incarceration has negative effects on well-being, including increased behavioral problems in children and burdens on grandparents.
University of Illinois Chicago researchers discovered a function of mammalian target of rapamycin complex 2 in an antiviral defense mechanism, limiting HSV-1 virus infection through rapid activation of antiviral immunity. The protein complex protects the host by preventing encephalitis and possible death due to HSV-1 infection.
The study analyzed SARS-CoV-2 genomic surveillance data from England, identifying key variants like Alpha and Delta that changed the course of the epidemic. These variants led to significant growth advantages, with Delta's growth rate being 59% higher than Alpha's, more than doubling the average growth rate of the virus.
A team of researchers has identified the KDM1A gene as responsible for a rare form of Cushing's Syndrome caused by abnormal expression of the GIP hormone. The discovery provides an early diagnosis tool and personalized medicine options, improving patient outcomes.
Researchers analysed publicly available comments in response to nature video content on Facebook during the UK's first national Covid-19 lockdown. The study found that engaging with this virtual nature content helped people cope with stress and mental fatigue, and increased feelings of connectedness to nature and others.
Scientists harness light to alter solid properties and create new applications for high-speed information processing, lossless energy transfer, and quantum technologies. The team reviews the latest developments in ultrafast materials science and explores unifying themes for controlling materials with light.
Scientists have improved understanding of a key protein that makes the stomach acidic, shedding light on potential applications in drug development. The study found an unusual feature in the protein, which needs to bind to only one potassium ion to trigger its pump mechanism.
Researchers created noninfectious SARS-CoV-2 replicons that mimic the viral life cycle and can be used to test drugs and neutralizing antibodies. The replicons can also identify human proteins necessary for viral replication and screen chemical libraries for antiviral compounds.
Scientists confirm a link between planetary and stellar compositions, with some planets exhibiting higher iron content than their host stars. This study provides insights into planetary formation and evolution, shedding light on potential habitability and constraining possible compositions.
Infection with measles virus triggers the activation of both RNA and DNA virus immune responses. The virus affects mitochondrial growth and division, causing their fusion and release of mitochondrial DNA into the cytoplasm. This leads to the activation of the cGAS immune response, which is also triggered by DNA viruses.
A significant proportion of US adults consider the use of facial image data in healthcare unacceptable, particularly when used to monitor emotions or symptoms. Many respondents (30-50%) expressed concern over facial recognition technologies in various scenarios.
Researchers developed a predictive tool using %V bur (min) to categorize phosphine structures as active or inactive in many experimental datasets. This advancement will facilitate organometallic chemistry and catalysis, enabling easier computation and prediction of phosphine reactivity.
A new study reveals the devastating impact of COVID-19 on public health, with the workforce experiencing extreme exhaustion and burnout. The pandemic response has swamped healthcare workers, leaving critical services such as chronic disease prevention, maternal-child health, and environmental health on hold.
Researchers used stable isotopes and fatty acids to unlock the secrets of jellyfish feeding. They found that jellyfish diets could look quite different than expected, with some species not incorporating certain prey into their bodies.
A special collection of articles reviews the application of photobiomodulation therapy for dementia, Alzheimer's disease, and other brain conditions. The therapy has been shown to promote microcirculation, cellular proliferation, and regeneration, reducing pain, inflammation, and oxidative stress.
Researchers developed a program to target vaccinations using digital contact tracing technology, which can almost halve the number of vaccines required to bring the pandemic under control. The new program prioritizes individuals with the most contacts for vaccinations while keeping personal data private.
A new study documents the formation of a 3,000-square-kilometer rift in the oldest and thickest Arctic ice, indicating the Last Ice Area may not be as resilient to climate change as previously thought. The polynya is unusual due to its location off the coast of Ellesmere Island, where ice is up to five meters thick.
Researchers at UC Berkeley engineered bacteria to produce an unnatural molecule through a combination of synthetic chemistry and biology. This breakthrough enables the creation of previously impossible chemicals, paving the way for sustainable materials and innovative products.
A new paper from University of British Columbia expert Dr. Mary O'Connor emphasizes the need to consider feedbacks in biodiversity research and policy making to mitigate negative consequences for humans. The authors propose building national and global biodiversity observatories to monitor ecosystems and human activities, enabling data...
Rice University's Neuroengineering Initiative is working on developing noninvasive systems to monitor and control the brain. Jerzy Szablowski aims to achieve single-cell precision in 15-20 years through innovative receptor development and gene therapy.
The study found that early Homo sapiens had an omnivorous diet in the tropical rainforest of Southeast Asia, consuming both plants and animals. The zinc isotope analysis revealed a mix of specialized adaptations to this environment, differing from previous assumptions about human diet.
A study published in the Journal of Infectious Diseases found that children can carry high levels of live, replicating SARS-CoV-2 virus in their respiratory secretions, with no correlation between age and viral load. The researchers also noted that viral loads are highest early in the illness in both symptomatic and asymptomatic children.
Researchers have identified a new pathway for opioid-induced reward in the brain, paving the way for creating safer opioids. By altering the opioid peptide receptor MOPR, pharmaceutical companies can potentially create drugs that bypass the brain's reward system.
New research from WVU suggests that live music can reduce pain and anxiety in pediatric critical-care patients. In a study, babies who heard live music had lower heart rates and slower breathing rates compared to those who listened to recorded music.
Researchers discovered how neurons in a small area of the brain filter distracting signals to coordinate dexterous movements. The findings may hold lessons for building better prosthetics and robots that can fine-tune their movements based on sensory input.
Researchers have demonstrated a new wavelength-tunable, silicon photon-pair source integrated with a pump rejection filter in a single CMOS chip. The device represents an important step toward an entangled photon source that incorporates active photonic devices and feedback control circuits on the same CMOS chip.
A 13-year-long study finds that fiber-reinforced polymer (FRP) coatings can sustain concrete structures for extended periods. The study tested FRP and glass fiber reinforced polymer (GFRP) systems under various environmental conditions, revealing significant impact on bond behavior.
Rice materials scientists develop a method to print arbitrary 3D shapes, creating micro-scale electronic, mechanical and photonic devices. The process involves two-photon polymerization and doping with rare earth salts for photoluminescent properties.
A new methodology creates a watershed-scale flood model based on LiDAR data, providing precise elevation readings and riverbed depth information. The system can predict flood conditions and provide warnings to area residents, making it applicable to large rivers and smaller streams.
A team of scientists from Germany develops a novel all-fiber based endoscopic set-up for multimodal non-linear endoscopy, allowing for the reliable assessment of tissue and successful surgery. The probe enables label-free tissue diagnostics, including tumor margin detection, and has the potential to improve patient care and reduce costs.
Research by Karolinska Institutet suggests that longer breastfeeding and later introduction to gluten may reduce the risk of developing type 1 diabetes. The study analyzed 5,935 articles and found a significant protective effect against the disease.
A team of bioinformaticians at Friedrich Schiller University Jena developed a method to identify small active substance molecules using machine-learning methods. They successfully identified 11 new, previously unknown bile acids in mice using this approach.
A study found that snakes rapidly diversified their diets following the K-Pg mass extinction event, incorporating birds, fish, and small mammals into their diet. This diversification was triggered by ecological opportunities presented by the extinction, with some lineages experiencing further bursts of adaptive evolution.
Researchers found that tweets with negative valence and consumer orientation generate permanent price impacts, while those with positive valence and competitor orientation increase temporary price impacts. Firms can design social media content to improve firm value by incorporating attributes such as valence and subject matter.
The University of Missouri is developing an online certificate program for clinical engineers through a $2.6 million grant from the Missouri Department of Higher Education and Workforce Development. The program aims to increase the number of trained and qualified clinical engineers in the workforce, particularly in rural communities.
Researchers at Georgia State University found that singing and imagining improvised music elicits the same flow-like brain states as when musicians are actually performing. The study used fMRI data to identify how a musician's brain reconfigures connectivity depending on the degree of creativity required during jazz performances.
A new study identified thousands of protein connections to various human diseases, suggesting a common origin in the genome. This approach linked genetic variations to specific proteins, providing insights into disease mechanisms and potential treatment strategies.
A University of Queensland study found that people exposed to higher amounts of the insecticide Malathion have a 25% higher risk of kidney dysfunction. Chronic kidney disease is a permanent condition characterized by loss of renal function and is often associated with age, hypertension, and diabetes.
Researchers developed a computational method to estimate new infection rates from genomic sequences, revealing decreased case detection in Europe during summer 2020 due to relaxed testing criteria. The study also highlights the effects of non-pharmaceutical interventions on COVID-19 spread.
Researchers found that vitamin D supplementation with calcidiol increased the expression of genes related to cell adhesion and migration, pathogen recognition, and pathogen killing in dairy cows. This suggests a possible link between vitamin D and enhanced immune function, particularly during early lactation.
Researchers at VCU used fMRI to examine brain activity of couples experiencing intimate partner aggression, finding a unique brain signature in the medial prefrontal cortex. The study also found that blunted activity in this region predicted real-world acts of intimate partner violence.
A large population study found that statin treatment was associated with a slightly lower risk of dying from COVID-19. The results suggest a moderate prophylactic effect on mortality, supporting the continued use of statins for conditions like cardiovascular disease and high blood lipids.
Researchers at LMU have identified a new silencing factor for ERV genes, enabling the formation of condensed chromatin structures that inhibit activation. This discovery sheds light on the role of histone variants in regulating gene expression and may have implications for treating autoimmune diseases and cancers.
A new study aggregates evidence from experiments on performance incentives globally, finding that men and women respond similarly to rewards for achieving performance objectives. The study suggests that performance pay boosts productivity for both genders across various contexts and program designs.
Scientists from the University of Tsukuba have developed a new technique to preserve Drosophila primordial germ cells, which can be used to produce new offspring. The cryopreserved PGCs were found to be effective after up to 400 days of long-term storage.
A new composite ink composed of ceramic particles in polymer acrylonitrile-butadiene-styrene (ABS) has been developed to make foldable electronics easier and cheaper to manufacture. The ink enables the creation of flexible, large-area dielectric substrates suitable for millimeter-wave devices, including 5G antennas.
A high intake of alpha linolenic acid (ALA), found in nuts, seeds, and plant oils, is associated with a lower risk of death from all causes and diseases of the heart and blood vessels. However, further studies are needed to confirm the association with cancer mortality.
Researchers have developed chimeric exosomes that co-activate the immune system to combat tumors. The therapy targets solid tumors, where the immune cells are often compromised, and improves treatment outcomes for patients.
A new study by Carnegie Mellon University researchers found that Airbnb units cause a mild decrease in long-term rental supply, including affordable housing, while expanding the rental market. The study suggests a new tax to alleviate resulting inequities and maintain social equality.
A recent study published in PaleoAmerica journal challenges the long-held theory that Native Americans originated from Japan. The research, led by Professor Richard Scott, analyzed genetics and skeletal biology of teeth samples from multiple continents, finding little connection between the Jomon people and Native Americans.
A new OSU study reveals that sunscreen containing zinc oxide loses its effectiveness and becomes toxic after just two hours of exposure to ultraviolet radiation. The research used zebrafish to test the toxicity of photodegradation products, finding significant increases in defects in the fish.