Researchers at Tufts University successfully regrow a functional, nearly complete limb on adult frogs using a five-drug cocktail and silicone wearable bioreactor dome. The treatment sets in motion an 18-month period of growth restoring a fully functional leg.
Regular physical activity significantly changes metabolite profiles, associated with a lower risk of type 2 diabetes. The study found improved insulin secretion and reduced fasting glucose levels in physically active men.
A clinical trial shows that an automated insulin delivery system using an Android app is safe and effective for young children with type 1 diabetes. The system, CamAPS FX, improved metabolic control and reduced blood glucose levels in children aged one to seven years.
A team of scientists at Brookhaven National Laboratory has identified a molecule with significant potential to disable the COVID-19 virus. The molecule was discovered using high-throughput virtual screening and laboratory experiments, and its ability to bind to the virus's main protease was confirmed through structural studies.
Natural supplements taken by athletes may pose serious health risks, including cardiovascular effects and contravention of anti-doping rules. Athletes often have limited knowledge about supplement effects on sports performance and overall health.
Researchers at HKUMed have discovered a stepwise upregulation of polymeric immunoglobulin receptor (pIgR) in circulating extracellular vesicles from liver cancer patients, suggesting its potential as a non-invasive diagnostic marker. The study also found that pIgR-enriched EVs promote cancer stemness and tumorigenesis in mouse models, ...
Researchers have designed a novel thermal armour that successfully inhibits the Leidenfrost effect up to 1,150°C and achieves efficient liquid cooling across a wide temperature range. The breakthrough has significant implications for applications in aerospace, space engineering, and next-generation nuclear reactors.
A review of 392 clinical trials found increased representation of diverse groups in dermatology trials for common skin conditions. The study also highlighted persistent disparities in clinical trial participation among underrepresented populations.
Samuel Galgano and Pankaj Gupta have been named the 2022 Melvin M. Figley Fellow in Radiology Journalism and the 2022 Lee F. Rogers International Fellow in Radiology Journalism, respectively. They will attend the 2022 ARRS Annual Meeting and participate in the Editor’s Forum.
A recent study found that individuals with Parkinson's disease who consume three or more servings per week of flavonoid-rich foods like berries, red wine, and tea have a lower chance of dying during the study period. Higher flavonoid consumption is associated with better survival rates in both men and women.
Scientists at Huazhong University of Science and Technology have created a new type of fiber optical tweezers that can trap particles using transverse electromagnetic modes. This breakthrough enables the manipulation of single biomolecules like DNA and proteins, opening up new possibilities for bioparticle research.
The COVID-19 pandemic has significantly increased the generation of medical waste, with daily output surging from 200 tons to over 29,000 tons in September 2020. The study also highlights the need to update emergency medical waste treatment strategies and manage personal protective equipment waste effectively.
A retrospective study found that dual-energy CT examinations performed in 2019 had a significantly lower frequency of equivocal interpretations compared to those in 2013. Joint aspirations were also less likely to be performed after negative DECT interpretations in 2019.
A study analyzing US SEER data from 2000-2016 found that younger age groups experienced the steepest increase in distant-stage early-onset colorectal adenocarcinoma incidence. Younger non-Hispanic Black and Hispanic populations showed greater proportions of distant-stage disease.
Researchers at UMass Amherst developed a gear-shaped photonic crystal microring that increases light-matter interactions without sacrificing optical quality. The device boasts an optical quality factor 50 times better than previous records.
Physicists at MIT have discovered a new type of qubit, where vibrating pairs of fermions can exist in two states at the same time. The qubits can maintain this state for up to 10 seconds, making them a promising foundation for quantum computers.
A new dataset examines publication patterns across 170 academic disciplines to provide more nuanced comparisons. The data reveals significant variation in publishing activity and venue preferences among scholars.
Researchers found that mitochondria can respire away harmful substances to protect protein folding, revealing an unexpected 'patron saint' role. This mechanism is triggered by reductive stress and protects proteins destined for export, showcasing the flexibility of plant mitochondria.
A study by Michigan Medicine reveals that 25% of young American men experience both delivering and receiving technology-facilitated abuse. Healthcare providers should consider addressing this issue, as men who have mental health care visits are more likely to be involved in abusive relationships.
The National Science Foundation's CyberCorps Scholarship for Service program will provide training and scholarships to the next generation of information technology experts and security managers. The Binghamton University partnership aims to diversify the workforce with a focus on attracting underrepresented minorities.
A team of researchers has created a prototype 'smart saddle' that utilizes self-powered triboelectric nanogenerators to analyze equestrian biomechanics. The device can detect subtle cues from the rider's posture, seat, and legs, as well as alert others in case of a fall.
A groundbreaking study published in the Journal of Nutrition found that a 'food-as-medicine' approach can significantly lower LDL cholesterol levels, with participants experiencing an average 9% decrease within 30 days. This innovative intervention expands treatment options for high-risk patients unable or unwilling to take statin drugs.
A joint project by Paderborn, Rostock, and Mainz universities aims to develop new iron compounds that can convert sunlight into chemically usable energy. The researchers hope to reduce greenhouse gas emissions and create a more sustainable future.
A new überreview provides a comprehensive introduction to solar resource assessment and forecasting, helping bridge the gap between atmospheric scientists and solar engineers. The review compiles recent studies on critical parameters like cloud and aerosol, aiming to facilitate interdisciplinary collaboration for carbon neutrality.
Research found that preschoolers' melatonin levels are suppressed by even dim light before bedtime, with suppression rates ranging from 70% to 99%.
Two observational studies provide reassuring data on menstrual changes after COVID-19 vaccination, finding that any changes are short-lived and small. The studies, which drew from US and Norwegian data, suggest that cycle lengths return to normal by two cycles after vaccination.
Researchers at Boston Children's Hospital have developed an organoid platform that identifies drugs that enhance enteroendocrine cell action, potentially reversing diabetes, obesity and gastrointestinal conditions. The system identified three chemicals that drive the formation of EE cells and hormone production.
New research in Marketing Science reveals that banning tobacco products can result in a 4% decline in gross sales for retailers. The study also suggests that the impact of such bans can be felt across other unhealthy product categories, affecting overall store revenue.
Researchers at Durham University have identified a medieval text written by Benedictine monk Gervase of Christ Church Cathedral Priory as the earliest known account of ball lightning in England. The description, composed around 1200, matches historical and modern reports of the phenomenon.
Researchers have created a new solid electrolyte that enables fast hydrogen conductivity in the intermediate temperature range of 200-400°C. This breakthrough could lead to more efficient fuel cells and electrochemical reactors for sustainable energy.
A team of researchers from Lund University analyzed ice cores from Greenland and Antarctica to discover a massive solar storm occurring during a quiet phase about 9,200 years ago. The study challenges the current understanding that solar storms are more likely to occur during active phases of the sun.
A new study suggests that music therapy can significantly decrease depression scores and help reduce menopause symptoms in postmenopausal women. This innovative approach has the potential to be used as a nonpharmacologic therapeutic option for managing menopause symptoms, particularly mood symptoms.
The research group developed a new method to test quantum gates with high efficiency and robustness, achieving optimal sample complexity without increasing with scale. Using this method, they tested CNOT and Toffoli gates, requiring significantly fewer measurements than traditional methods.
A new standardised test has been developed to accurately determine the transmission of VREfm, enabling rapid identification of potential outbreaks and early intervention. The framework uses genomic analysis to compare bacterial genomes and infer transmission links, facilitating global deployment for outbreak detection and investigation.
Physical activity monitors provide direct feedback, leading to small to moderate increases in daily steps (1,235 extra steps) and moderate to vigorous physical activity (50 extra minutes per week). The evidence suggests these devices may be useful for adults who don't meet recommended activity levels.
A new study found that diet can cause significant changes in the gut microbiota, leading to long-lasting genetic alterations. In mice, a low-fiber Western-style diet led to the emergence of adaptive mutations in a key species of bacteria, shaping its function and increasing host susceptibility to infection.
The COVID-19 pandemic significantly increased job demands on primary care teams, but new skill development opportunities and sense of purpose boosted staff morale. Management support played a crucial role in mitigating burnout, with participants reporting greater support and patience within their practices.
The University of West Virginia leads a global initiative to integrate behavioral and social sciences into oral health promotion, aiming to reduce dental disparities and inequities. The effort involves innovative technologies like apps and smartphones to increase access to dental care.
Researchers at University of Illinois Chicago identified changes in the gut microbiome that can lead to gestational diabetes. They found a specific metabolite, kynurenine, that is increased during pregnancy and contributes to insulin resistance.
A multilevel program improved the awareness and adoption of buprenorphine treatment for opioid use disorder in rural Colorado. The program increased the proportion of practices providing or referring patients for treatment from 18.8% to 74.4%, with a significant increase in buprenorphine prescriptions over four years.
A two-year randomized trial found that cannabis use significantly impaired driving ability, particularly in the first few hours after smoking. Despite varying levels of THC content and user history, participants displayed diminished skills on simulated driving tests.
A study found that subtle changes in heart structure and function between early adulthood and middle age are associated with declines in thinking and memory skills. The research, published by the American Academy of Neurology, suggests that a single echocardiogram may help identify people at higher risk of cognitive impairment.
A new study reveals anatomic differences in the inner ear structures of two major bat groups, influencing the evolution of diverse echolocation and foraging forms. The absence of Rosenthal's canal in Yangochiropterans allowed for unique behavioral adaptations.
Researchers at the University of Groningen have developed an AI system that can recognize indoor spaces with high accuracy by combining image and audio data. The system achieved a 70% accuracy rate in recognizing nine different types of indoor spaces, surpassing previous results.
Researchers analyzed over 60 million GitHub posts to find that developers who don't use emojis are three times more likely to drop off the platform. Emoji usage patterns varied among developers, but were associated with factors like work type and time management.
New insights into cloud behavior in the southern hemisphere reveal a stronger influence of updrafts, resulting in liquid water droplets and altered radiation balance. This study, led by Leibniz Institute for Tropospheric Research, uses long-term measurements to improve climate models.
A study published in PLOS ONE suggests that changing climate conditions 23,000 years ago expanded food options for humans in Israel's Sea of Galilee region. The research analyzed animal remains at the submerged archaeological site of Ohalo II, revealing a diverse diet with multiple prey sources.
A study by Politecnico di Milano reveals that large-scale land acquisitions for agriculture lead to increased water scarcity, impacting local users. The research analyzed 160 acquisitions and found that 105 resulted in competition for water, often at the expense of local communities.
Researchers have developed an ultrasensitive bioelectronic tongue that mimics human taste buds to measure sweetness. The device responds to sweet-tasting compounds at the 0.1 femtomolar level, making it a powerful tool for industries such as healthcare and food.
Researchers identified four metabolites that indicate adherence to a Mediterranean diet, while ultra-processed foods consumption was associated with lower levels of these metabolites. The study's findings support public health efforts to recommend increased Mediterranean diet adoption and limiting ultra-processed food intake in childhood.
Researchers have developed an entirely new paradigm to image objects through diffusive media. A deep learning-based approach uses diffractive surfaces to optically reconstruct distorted images without digital processing. This computer-free method has significant potential for advancements in fields such as biomedical imaging, astronomy...
A new study reveals a link between over-activity in the hippocampus and certain schizophrenia symptoms, including negative symptoms such as reduced motivation and disrupted emotional processing. The findings have important implications for developing more targeted treatments for these symptoms.
Technology-facilitated abuse is common among young men in the US, with 38% reporting experiences in the last year. Primary care doctors are urged to adapt intimate partner violence screening tools for male patients, including technology-facilitated abuse assessment.
A trial of older US adults found that vitamin D and omega-3 fish oil supplements reduced the risk of autoimmune diseases by 22-30% compared to placebo. The effects were more pronounced after two years of supplementation.
Decision-making tools, including a double-sided document and video training, were ineffective in reducing antibiotic prescription rates for acute respiratory infections. Despite this, general practitioners' knowledge of relevant evidence increased significantly after the intervention.
A team of researchers from Boston University School of Medicine has identified extracellular vimentin as an attachment factor facilitating SARS-CoV-2 entry into human endothelial cells. The study found that depletion of vimentin significantly reduces SARS-CoV-2 infection, while over-expression with ACE2 increases the infection rate.
A national analysis of lung transplantations performed in the US between August 2020 and September 2021 shows that 7% of lung transplants were performed to treat COVID-19-related lung damage. The study suggests that lung transplantation may be a safe option for select patients with severe, irreversible lung damage.
A new portable $51 testing kit can provide fast and reliable COVID-19 detection in resource-poor regions, refugee camps, and disaster zones. The non-invasive saliva sampling system uses a technique similar to PCR testing, with costs comparable to commercial tests.
A new study at Instituto Gulbenkian de Ciencia founds repulsive forces generated by microtubules scaffold keeping nuclei at a distance. These interactions reorient nuclear divisions towards unoccupied regions, maintaining uniform distribution of nuclei in developing embryos.
A recent study found that block periodization with either increased low-intensity training volume or high-intensity interval training improved endurance performance in recreational athletes. Both methods resulted in average time improvements of 11-13 seconds on a 3000m run.