This review highlights the potential of nanocarriers in cancer treatment, including liposomes, solid lipid nanoparticles, polymeric nanoparticles, dendrimers, and inorganic nanoparticles. The combination of these technologies with magnetic hyperthermia and viral nanoparticles offers a promising approach to treating malignant tumors.
Michigan State University scientists have pinpointed the molecular 'switch' that supercharges sperm for their final sprint to an egg. The discovery could reshape infertility treatments and pave the way for a new generation of male contraceptives.
Researchers from the University of Tokyo developed a method to use microwaves to heat specific areas in industrial processes, reducing energy costs and improving selectivity in chemical reactions. This technique has the potential to optimize catalyst design, improve durability, and scalability for eco-friendly industrial processes.
Scientists at Institut Pasteur and Inserm developed a triple-therapy approach to treat blood cancers like lymphomas and leukemias. They induced necroptosis in malignant B cells, which activates the immune system to eliminate tumor cells.
The National Association of School Nurses reaffirms its commitment to school immunization requirements, citing the life-saving role of vaccines. The updated position statement recommends eliminating vaccine exemptions except in medical contraindications, emphasizing the importance of timely and complete vaccinations.
SourceSAGE·JournalThe Journal of School Nursing·TypeCommentary/editorial·DateOct 10, 2025
A new study finds that glaciers will likely reach their peak of self-cooling power in the 2020s-2040s before near-surface temperatures spike up and melting accelerates. The research, led by Thomas Shaw, used an unprecedented dataset of on-glacier observations worldwide to demonstrate this trend.
Researchers at Drexel University have developed MXene current collectors that can improve the capacity of lithium-ion batteries while reducing their size and weight. The new components are also recyclable, which could help reduce battery waste and conserve limited material resources.
Researchers identify disease-associated radial glia-like cells that contribute to persistent inflammation and neurodegeneration in progressive multiple sclerosis. These cells exhibit characteristic features of radial glia and display hallmark features of premature aging, fuelling a toxic environment that accelerates neurodegeneration.
A Kinsey Institute study found that gaps in sex education can have lasting impacts on adult relationships, including relationship struggles, lack of confidence, and reduced quality of life. Most participants learned only a few topics in school, with many lacking information on healthy relationships, consent, and communication.
A new Cornell University study models impacts of different emissions trajectories, finding that delayed reductions substantially reduce chances of avoiding thresholds for sea-level rise. The study estimates a 50% probability of reaching a 0.4-meter sea-level rise threshold by 2050 if emissions aren't reduced by 2050.
Studies have found that men with advanced prostate cancer can benefit from continuing PSMA therapy despite early PSA rise, while a new PET/CT scan may improve surgery decisions in pancreatic cancer. Molecular imaging advancements also hold promise for distinguishing aggressive kidney cancers and guiding treatment decisions.
Researchers found that hosts harboring different microbial strains exhibited neurobehavioral differences. The study identified 34 significant associations between microbial single nucleotide variations and host plasma metabolites, primarily related to key physiological processes such as neuroactive regulation and oxidative stress.
Researchers found that females with ADHD are underdiagnosed and often receive a diagnosis five years later than males. They also exhibit greater emotional and functional difficulties.
A new study found that COVID-19 work absences have become a year-round phenomenon in the US labor market, similar to pre-pandemic influenza season conditions. Nationally representative data can help monitor public health crises and inform policy decisions.
Researchers engineered Escherichia coli to produce inosinic acid, a popular umami enhancer, with significantly increased yields. The engineered strain produced 562.0 mg/L of IMP, a 4.77-fold increase over the wild-type strain.
Ben Jones, UTA physics professor, receives $1.3 million grant to search for rare processes involving neutrinos. The grant supports his project on neutrinoless double electron capture in argon or krypton gases.
The study found that eliminating race-conscious admissions led to a decline in medical school diversity, threatening progress toward healthcare equity. Medical schools must explore alternative admissions strategies to address structural barriers and maintain diversity.
The ACMG has established a Newborn Screening Coalition to maintain national oversight and evaluation of genetic disorders, ensuring continuity in the nation's newborn screening system. The coalition will uphold standards of evidence-based review and transparency.
A study using respondent-driven sampling (RDS) found that factors like source of electoral information, education level, and trust in government influenced political participation. Undocumented immigrants were less likely to engage due to lack of information and distrust.
A team of Stanford investigators created a liquid biopsy using cell-free mRNA to diagnose ICI-related myocarditis, enabling tissue- and cell type-specific gene expression profiling. The study identifies a panel of genes associated with the immune response and heart tissue damage, allowing for early detection and treatment adjustment.
The book, 'The Nine Lives of Christopher Columbus,' examines the public perception of the Italian explorer's life and legacy. Restall separates fact from fiction to understand why Columbus continues to mean different things to different people.
A recent study published in Oncoscience found that lifestyle choices and hormonal imbalances significantly impact male fertility in Indian men. The research discovered a strong association between poor habits such as tobacco and alcohol use, heat exposure, and body weight with lower semen quality and higher DNA damage.
Researchers at the University of Cambridge have developed a hybrid device that combines light-harvesting organic polymers with bacterial enzymes to convert sunlight, water and carbon dioxide into formate, a fuel that can drive further chemical transformations. The new 'semi-artificial leaf' mimics photosynthesis and avoids toxic semico...
A 6-year cohort study found that people living in rental flats and owner-occupied detached houses face higher risks of cardiovascular death compared to those in owner-occupied flats. Improving housing quality to address colder indoor temperatures could lower cardiovascular mortality, particularly among men.
A study of 200 classrooms found that HEPA purifiers did not significantly reduce respiratory viral exposures, suggesting additional interventions are needed. Maintaining classroom humidity between 40% and 60% may help lower viral exposures and improve comfort for students and teachers.
Researchers have developed a new type of light-controlled non-volatile memory, leveraging circularly polarized terahertz light pulses to switch between two stable states. This breakthrough offers promising candidates for stable and robust data storage.
Researchers at Columbia University have identified the rules for creating perfect polaritons, which are hybrid quasiparticles combining light and matter. The guiding rules include large optical absorption, low disorder, and inherent exciton delocalization, enabling polaritons to preserve coherence despite strong interactions and disorder.
University of Michigan researchers propose a technique called Dynamic Sensor Selection to identify disease biomarkers. The approach, which applies control theory and observability principles to biological systems, has been shown to pinpoint biomarkers at each time point and reduce data complexity.
Researchers aim to determine if biomarkers can identify adults at risk of developing interstitial lung disease (ILD), a chronic condition that causes inflammation and scarring in the lung tissue. The approach could lead to the development of new, better treatments with more tolerable side effects.
The University of Michigan's Center for Sustainable Systems has released its 2025 collection of factsheets, covering topics like energy, water, climate change, and transportation. The new edition includes two all-new sheets on artificial intelligence and the Great Lakes, with information gathered from over 1,270 reputable sources.
Wiley has acquired Nanophotonics, a top-ranked open-access journal in Optics & Photonics. The acquisition enhances Wiley's impact portfolio covering physics, engineering, and materials science, focusing on emerging photonics applications.
Researchers developed a new technique combining physical laws with artificial intelligence to identify material properties even under data-scarce conditions. The approach enables rapid exploration of new materials and improves experimental efficiency while preserving reliability.
A meta-analysis of 100 studies across psychology, sociology, economics, and engineering found that positive attitudes toward conserving electricity are key to saving energy. Individuals who think others expect them to conserve power and have pro-environmental habits tend to save more energy.
Scientists have identified a new phase of warm ice, called ice XXI, which forms when water is rapidly compressed to supercompressed water at room temperature. The discovery offers insights into how high-pressure ice forms and may lead to new findings about the composition of icy moons.
The study found that the reduction in grain consumption was the primary reason for the decline in zinc intake. Zinc obtained from grains decreased significantly, while meat consumption only partially offset this impact. Regional differences were also observed, with certain provinces experiencing higher rates of insufficient zinc intake.
Geoffroy Hautier, a materials scientist at Rice University, has been elected a fellow of the American Physical Society for his groundbreaking research in high-throughput computational materials design and discovery. His work bridges quantum mechanics, computation, and artificial intelligence to accelerate the discovery of new materials...
The study presents a comprehensive review on electric-field-driven generative nanoimprinting for fabricating complex nanostructures. This technology has the potential to overcome limitations of traditional lithography and enable the creation of next-generation nanomanufacturing technologies.
Chapulines, a traditional Mexican food, have changed meaning over time from poor people's fare to tourist novelty. Locals consider them an essential source of protein, while women who sell chapulines are vital breadwinners for their families. The COVID-19 pandemic even saw innovative touchless sales during market closures.
A cohort study found that 40% of GLP-1RA orders were not filled, with lower rates among Non-Hispanic Black and Hispanic patients. These disparities may be attributed to differences in insurance coverage, GLP-1RA use, or cost thresholds.
New study reveals hippos inhabited Upper Rhine Graben in southwestern Germany between 47,000 and 31,000 years ago. The discovery challenges previous understanding of hippo extinction in central Europe during the last ice age.
A macroscopic device has been designed to reduce eddy-current damping, allowing for precise measurements of physical phenomena like gravity. The system uses a graphite disk and rare earth magnets, enabling ultra-precise sensors that can be used in classical and quantum physics research.
A polymer 'Chinese lantern' structure can snap into multiple curved shapes, controlled by a magnetic field. Researchers developed a mathematical model to program the shape and energy release, enabling diverse applications such as non-invasive grippers and filter systems.
Researchers at Kyushu University have developed a new method to build more energy-efficient magnetic random-access memory (MRAM) using thulium iron garnet. The team successfully produced thin films of platinum on the TmIG material, enabling high-speed and low-power information rewriting at room temperature.
Coccolithophores are microscopic ocean organisms that regulate Earth's climate by drawing carbon out of seawater, producing oxygen, and creating chalk and limestone that preserve climate history. Climate change is altering their survival and the ecosystems they support, making International Coccolithophore Day a crucial awareness campa...
Scientists have discovered how to generate an electron gas by illuminating a material made of layers of oxides, enabling light-controlled electronic components. This breakthrough could lead to applications in spintronics and quantum computing, with potential energy savings of up to a third of electrical contacts on computer processors.
A longitudinal study of over 700 university students found that stress sensitivity increases the frequency, intensity, and variability of suicidal thoughts. Stress sensitivity was also found to intensify the frequency and variability of suicidal thoughts among students with intense, frequent, and persistent ideation.
A new study on Ascension Island's shark troubles has found that human attitudes towards interactions with sharks can drive global decline in shark numbers. The research, conducted by the University of Exeter and ZSL, interviewed islanders about their perceptions of sharks and human-shark conflict.
Researchers from the University of South Australia explore the connection between the gut and brain to decipher their role in mental health and wellbeing. The study found that changes in the gut microbiome can directly affect brain chemistry, suggesting a potential link between gut health and mental illness.
Scientists have discovered a surprising strategy plants use to thrive in sulphur-deficient conditions by releasing glutathione, which enhances plant growth but reduces bacterial growth. This 'trans-kingdom fitness trade-off' has implications for designing better microbial solutions for resilient crops.
Denis Evseenko and Toby Maher are developing a regenerative drug to block cells that promote fibrosis in the lungs, aiming to slow or reverse IPF damage. The team plans to test the safety and therapeutic potential of their drug-like molecules in animals and human cells.
A collaborative team at Scripps Research is creating the first atlas of interoception, a process by which the nervous system monitors physiological signals to maintain vital functions. The team aims to build a comprehensive framework for mapping internal sensory pathways using $14.2 million NIH funding.
A study analyzing S. macrophylla's natural populations in Kalimantan revealed distinct genetic structures among northeastern, central, and southwestern populations. The ancestral population shows highest genetic diversity and is recommended for conservation as a separate management unit.
The East Asian Summer Monsoon has shaped the genomic evolution of Engelhardia species through significant variations in genome size and gene number. Phylogenomic analyses reveal divergence between evergreen and deciduous lineages around 52 Mya, coinciding with EASM intensification.
The research emphasizes the importance of coordinating China's multi-level carbon markets in the context of global carbon pricing. Local pilot markets are seen as experimental fields for innovation, covering small enterprises and promoting regulatory experimentation.
Researchers developed a multiphysics model that couples electrochemical and mechanical dynamics in all-solid-state batteries. The model enhances interfacial stability and lithiation kinetics by regulating electrochemical potential gradients.
Researchers have developed a novel electrolyte design for potassium-ion batteries using fluorinated triethyl phosphate, enabling fire-retardant and high-performance electrodes. The electrolyte supports reversible potassium storage in graphite anodes and addresses key barriers in PIB commercialization.
Researchers developed DeMemSeg, an AI-driven pipeline that accurately segments overlapping membrane structures with accuracy comparable to expert manual analysis. The approach enables large-scale, objective, and quantitative analysis of morphological data, providing a foundational technology for advancing disease mechanisms.
Researchers analyze the 'dead Mn' dilemma in MnO2 chemistry, proposing strategies to enhance electrochemical reversibility and cycling stability. Mitigation approaches include optimizing deposition conditions, regulating proton supply, and reactivating inactive species using redox mediators.
Researchers at University of Tsukuba predicted the intensity of 21-cm radio signal in different dark matter models using numerical simulations. The results imply hydrogen gas produced a characteristic signal that could reveal dark matter mass and velocity if detected globally.
A recent study published in Medical Research Archives found that incorporating canned beans into a diet reduces shortfalls in essential nutrients and improves overall diet quality among U.S. adults. The research also highlighted the impact of replacing high-protein foods with canned beans on achieving optimal nutrient intake.