The LEEP program has enabled the success of over 51 startups, with nearly $100 million in sales revenue and $326.8 million in follow-on funding. The program's translational success is mirrored in the success rate of LEEP-supported startups, which have experienced a 92% success rate.
Researchers have discovered a new, previously unknown biofluorescent trait in the fire salamander, which may facilitate communication among individuals and influence mating behavior. The phenomenon is thought to be linked to toxic secretions on the animal's skin.
A small study of 100 Italian college students reveals that discussing fake news in a group enhances its identification, thanks to collective critical thinking and social cues. The research suggests that shared discussions can improve fake news detection, making it easier for individuals to distinguish between true and false information.
Researchers identified strong Brønsted acid sites in fluorinated γ-Al₂O₃ using state-of-the-art NMR techniques. These sites enhance catalytic activity and aromatization performance, directly linking atomic-scale structure to macroscopic behavior.
Researchers at NC State University developed a morpho-interlocking protective module (MIPM) that responds to external threats and curls into a protective ball. The structure, inspired by armadillos' natural defense mechanisms, consists of multiple layers and can be tuned to respond to various levels of strain.
A new study reveals that maternal infection during pregnancy can lead to severe heart dysfunction in offspring, primarily due to oxidative stress and lipid peroxidation. Administering antioxidants or specific lipid peroxidation inhibitors can rescue mitochondrial function and restore healthy metabolic signaling.
The team developed the world's first gas-solid hydride ion prototype battery (g-HIB), which uses hydrogen gas and a metal as electrodes. The battery can store hydrogen under ambient temperature and pressure through an innovative mechanism, offering high efficiency and practicality.
Researchers from Zhejiang University present a comprehensive overview of stem cell-based strategies for treating traumatic brain injury. The study explores the therapeutic effects of stem cells, exosomes, and biomaterial scaffolds in promoting brain repair and functional recovery.
Scientists have successfully created perfect randomness using quantum physics, a breakthrough that could revolutionize digital security. By amplifying imperfect randomness, they can generate perfectly random numbers for encryption and other applications, rendering existing systems vulnerable to attacks.
Researchers found a clear divide in how gay and mainstream dating apps shape behavior and body image among Australian men. Gay dating apps encourage users to focus heavily on their bodies, leading to overwhelming pressure and negative self-talk.
UPL3 E3 ubiquitin ligase promotes light-induced seed germination by degrading PIF1. The study reveals a critical role for UPL3 in mediating PIF1 degradation through the 26S proteasome pathway.
A study published in Nature Communications has identified sialylation as a key mechanism by which breast tumours evade the immune system, leading to limited effectiveness of immunotherapies. Targeting this process may improve the efficacy of these therapies, providing new hope for patients with breast cancer.
Researchers developed PANDORA-seq to detect sncRNAs in human sperm, revealing strong correlations between specific molecular species and clinical indicators of sperm quality. The study established novel molecular frameworks for diagnosing male infertility.
Research reveals Neandertal ancestry affects immune system to multiple DNA viruses, including Epstein-Barr virus and human herpesvirus 7. Archaic DNA variants were disproportionately associated with higher viral loads in modern humans.
Researchers studied Chang'e-5 lunar regolith, identifying nanoscale evolution of surface materials through impact-induced silicate phase separation and formation of metallic iron. The findings provide new insights into spectral evolution of the Moon and processes responsible for forming lunar impact glass.
Researchers have developed an on-chip platform using ferroelectric spherulites to generate stable, broadband optical skyrmions across the entire visible spectrum. This breakthrough merges high-capacity data transmission with topological protection, opening new avenues for classical and quantum communication technologies.
A new Finnish study found that a healthy lipid profile is associated with better cognitive function in adolescents. Higher blood concentrations of markers indicating lipid dysfunction were linked to slower processing speed and poorer performance on tasks requiring fast information processing.
Scientists at KIT have discovered a way to control and manipulate superconducting vortices, which can be used as qubits in quantum technologies. The researchers found that these vortices can form stable low-loss states, allowing for the development of novel quantum systems.
Researchers have discovered that inflammation plays a dual role in atherosclerosis, both driving the disease's progression and limiting it. Macrophages, often seen as solely harmful, also clear cellular debris and attack endothelial cells, while microRNA miR-147 helps regulate this balance.
Researchers propose a new conceptual framework called Health Elements, which integrates technological factors alongside traditional domains as core drivers of health. The framework highlights the increasingly important role of digital infrastructures in shaping health behaviors and outcomes.
A study identified alterations in the endocannabinoid system associated with severe acute pancreatitis, including decreased circulating levels of 2-AG. Restoring 2-AG levels reduced inflammation and lung damage, highlighting the system's role in the disease's pathophysiology.
A new analysis argues that current scientific methods may not be capable of reliably answering questions about AI consciousness. The study highlights the importance of developing more precise methods to investigate subjective experience, crucial for evaluating claims about animal welfare, AI ethics, or bioethics.
Researchers successfully created a novel, stably inheritable grass carp germplasm without intermuscular bones using the runx2b gene. The absence of IBs did not affect the fish's quality or nutritional profile, but improved gel strength and resilience were observed.
The Salk Institute has promoted Julie Law to full professor and appointed Talmo Pereira as assistant professor, highlighting their innovative approaches to gene regulation and computational neuroscience. Their research focuses on epigenetics and artificial intelligence techniques, respectively.
A new simulation- and AI-based approach reduces the time and data needed for brain MRI scans, achieving a high level of accuracy with only 10% of the data required. This breakthrough could translate to a significant reduction in scan time, enabling more patients to be treated in the same amount of time.
The Max Planck Institute for Polymer Research has launched a new international visiting student program with Virginia Tech, providing six graduate and undergraduate students from the US with three-month research opportunities in Mainz. The Poly-ABROAD Program aims to strengthen international scientific exchange in polymer and materials...
A new study links amino acid-driven oxidative stress to therapeutic vulnerability in Acute Myeloid Leukemia (AML) by targeting the UCP2-BCAA-PI3K/AKT/mTOR signaling axis. Suppressing UCP2 impairs leukemic cell proliferation and triggers apoptosis, while BCAA-induced oxidative stress activates this pathway.
A new AI model developed by researchers at the University of Witwatersrand has successfully simulated human-like language development in children. The model, which uses deep linear neural networks, demonstrates how language structures and becomes more complex over time, mirroring how humans learn and transmit knowledge.
Research highlights the dual role of eosinophils in cancer, with higher counts associated with reduced risk and improved treatment response to immunotherapy. The immune-activating effects of eosinophils may help predict treatment outcomes and anticipate complications.
Researchers summarize how AI is accelerating inorganic biomaterial development for various biomedical applications. AI-powered property prediction and inverse design tools are being used to discover effective materials with unique properties.
A national analysis found that robotic-assisted cholecystectomy remained linked to increased bile duct injury risks despite growing use. The study suggests small differences in overall complication rates between approaches.
Scientists have developed a new method to manipulate heat transfer using carefully engineered metamaterials, boosting it by up to four times. This breakthrough could lead to more efficient cooling strategies for electronic devices, improved thermophotovoltaic systems, and enhanced sensing technologies.
Researchers at Duke University School of Medicine identified a new mechanism by which G protein-coupled receptors (GPCRs) control signaling in cells. They found that β-arrestin proteins can assemble into liquid-like clusters known as condensates, acting as hubs to organize signaling molecules.
Dr. Sharon Giordano and Dr. Eduardo Vilar-Sanchez receive ASCO Special Awards for their transformative work in breast cancer research and prevention, respectively. Their contributions advance understanding of cancer and improve patient outcomes.
A recent study published in JAMA examines the effectiveness of hearing aids for adults with mild to moderate hearing loss, highlighting the benefits and limitations of both prescription and over-the-counter devices. The research suggests that personalized fitting and follow-up care are crucial for optimal outcomes.
Researchers reconstructed the most detailed map of molecular machines that carried out life's functions in an ancient ancestor, revealing hundreds of new genes associated with human diseases. The study confirmed links between three rare disorders and identified potential targets for treating other diseases.
A new study projects that climate change will significantly increase the risk of heat-related cardiovascular disease in the US by 2050. The Pacific Northwest and Southern/Midwestern states are expected to experience the highest and steepest increases, respectively. Targeted interventions for vulnerable communities are crucial to mitiga...
Researchers have developed a cell-based delivery platform that uses encapsulated engineered cells to secrete cytokines directly within the wound environment, supporting accelerated wound healing in rodent and porcine excisional wound models. The approach is designed to maintain therapeutic levels of signaling molecules at the wound site.
A comprehensive long-term study has demonstrated the efficacy of molecular blood tests in influencing leukemia course. The study found that early intervention based on molecular markers can have a significant impact on disease progression.
A new study published in JAMA Network Open found that approximately 16% of patients with COVID-19 developed long COVID, translating to over 18 million Americans. The study used a novel AI algorithm to identify cases undetected by existing diagnostic systems.
A study by Harvard T.H. Chan School of Public Health found that gut microbiome alterations persist even after adenoma removal, increasing the risk of colorectal cancer. The researchers discovered that diet and physical activity were closely tied to CRC-associated gut microbes, suggesting lifestyle habits may contribute to sustained risk.
A recent study using motion-capture and particle image velocimetry reveals that the flutter kick generates three-dimensional vortex structures contributing to forward propulsion. The alternating leg movements also produce asymmetric vortices, generating rolling and yaw moments that stabilize body posture during swimming.
A new study published in Nutrition Research analyzed evidence from thousands of people and found that natural trans fats in dairy do not increase the risk of heart disease or type 2 diabetes. The research provides clarity on trans fat labelling policies, giving consumers reassurance about the safety of dairy foods.
Researchers highlight the promise of using human monoclonal antibodies to treat patients more effectively and tackle antimicrobial resistance. mAbs can be designed to target only the disease-causing bacteria, thereby protecting the microbiome.
A study published in Nature suggests that individuals at the extremes of certain traits, such as cholesterol and blood glucose, are more likely to have rare genetic variants with larger effects. This discovery may lead to better preventive care and treatments for those with extreme trait values.
Research using EEG reveals that caffeine can reduce slow-wave activity and shift brain patterns towards wakefulness, even if sleep duration appears normal. This can lead to a vicious cycle of fatigue and poorer sleep quality, highlighting the need for personalized approaches to caffeine consumption.
Children's Hospital Colorado has pioneered a groundbreaking approach to treating cystic fibrosis before birth, resulting in reduced NICU stays and improved pancreatic function. The pioneering care model uses ETI therapy to improve lung health and offers seamless continuation of treatment after birth through breast milk.
Researchers found a clear spike in fungal microfossils following the asteroid impact that wiped out the dinosaurs 66 million years ago. This global event, occurring tens of thousands of years before the extinction, suggests that volcanism may have contributed to the mass extinctions in that period.
A new antifungal aqueous suspension has been developed by Universitat Jaume I and GEA Biotechnology to prevent fungal infections in crops and fruit. The formulation, based on biodegradable chitosan microcapsules, offers a sustainable alternative to conventional synthetic fungicides.
Two projects, BOOST-HP and BIONIC, use machine learning to analyze large datasets of medication exposure and outcomes. The findings highlight the need for more data and cautious design of machine learning models to accurately assess potential links between medications and pregnant women.
Murnane recognized for pioneering ultrafast laser technology and XUV science, as well as exceptional mentorship and leadership. She has made seminal contributions to the field of optics with over 25 years of international leadership.
Researchers discovered that degrading mutant KRAS protein leads to greater lung cancer regression and more durable antitumor responses than conventional inhibitors. The study also identifies resistance mechanisms distinct from those previously described, offering new insights into targeted protein degradation therapies.
A research team found that tropical forest plants increase root carbon exudation to stimulate phosphatase activity, mineralize organic P, and release organic acids to dissolve mineral-bound P. This adaptation helps alleviate P limitation under long-term N enrichment, sustaining productivity.
Research from Washington State University found that graphic anti-smoking ads can lead smokers to vape instead of quit due to the lack of comparable health warnings on e-cigarettes. The study suggests that consumers may perceive e-cigarettes as a safer option when exposed to vivid images of smoking's health consequences.
A new viewpoint article highlights the risk of AI 'collusion' with unreliable human input in mental health settings. The author argues that clinical expertise should be included when designing training data and evaluating AI systems to strengthen safeguards.
Researchers at Binghamton University developed a system that enables users to monitor real plants in real-time using virtual reality. This technology makes farming more accessible for older adults and people with disabilities, allowing them to observe plants without physically being present.
Researchers at UC San Diego have identified a naturally occurring peptide that significantly slows melanoma growth, reduces tumor spread, and restores sensitivity in drug-resistant cells. The findings suggest CST could serve as the foundation for a new class of peptide-based therapies against advanced and therapy-resistant melanoma.
A team has developed a highly efficient glass screen that converts X-rays into visible light, capturing diagnostic images with less radiation. The new 'quantum glass' can be molded into curved shapes, enabling the creation of X-ray imaging systems that curve to fit a person's anatomy.
The National Comprehensive Cancer Network (NCCN) has launched a new free service providing weekly email updates on changes to evidence-based guidelines for cancer prevention, screening, treatment, and supportive care. The service aims to keep healthcare providers up-to-date with rapidly evolving evidence-based recommendations.
The American Cancer Society has updated its guidelines for colorectal cancer screening, introducing blood-based and at-home stool testing options to increase accessibility. The new recommendations aim to close the screening gap and detect more cancers at an earlier stage, with a focus on underserved populations.