Astronomers observed a galaxy protocluster at 1.2 billion years after the Universe's birth, finding it was already shaped by its environment. The Loktak Protocluster had larger, redder galaxies with more rounded shapes than isolated galaxies.
The study reveals that PFESA exposure significantly increases antibiotic resistance gene proliferation by restructuring extracellular polymeric substances and triggering cellular stress responses. This enhances the persistence of resistant taxa in microbial communities, posing a risk to human health.
Researchers have developed a breakthrough nanoscale circuit that can generate, direct, and read light-based information on a single chip. The device overcomes long-standing challenges in valleytronics, an emerging field that could underpin faster, more energy-efficient computing and quantum technologies.
Researchers developed S-NiFe-LDH catalysts with sulfur doping to optimize active sites for efficient urea oxidation. The incorporation of sulfur lowers the thermodynamic barrier, enhancing activity and kinetics. This work presents a cost-effective strategy for advancing sustainable hydrogen production.
A team of researchers identified multiple defects in macrophages that leave people with CF vulnerable to MABS infections. The study found that even the most effective CF drug doesn't boost macrophage's ability to kill MABS.
Two studies suggest that weight loss after bariatric surgery reduces cancer risk in women, with insulin levels and genetic background playing key roles. Women carrying a specific FTO genetic variant showed significant breast cancer risk reduction.
A nationwide study found 65% of China's freshwater is stored in remote western lakes, creating a severe spatial imbalance between water and population distribution. The Tibetan Plateau holds significantly more freshwater than the densely populated eastern plains.
A novel chromosomal instability-based signature, CIN score, guides survival prediction and immunotherapy response in breast cancer. High-CIN scores indicate poorer overall survival and unfavorable clinicopathological features.
A global meta-analysis of 8509 field observations found that plant-based and animal-based carbon inputs significantly improve agroecosystem multifunctionality. Soil biota abundance was strongly linked to multifunctionality and showed more frequent win-win relationships with other functions than species richness.
Researchers have overcome key safety and durability barriers in sodium-ion batteries by using a simple additive of graphitic carbon nitride. The additive promotes flexible, disordered zones where sodium ions move more freely and reduces polarisation, improving battery efficiency and stability. This breakthrough opens a scalable pathway...
Scientists have successfully decoded the polarization cipher of high-energy electrons, demonstrating a new pathway to creating highly polarized gamma-ray sources. The study's findings confirm key predictions of quantum electrodynamics and open up new design options for mid- to high-energy gamma-ray sources.
Researchers developed a chemo-mechanical switch that consumes virtually no power until detecting gas leaks, offering a clean alternative to traditional sensors. The device can detect hydrogen concentrations as low as 0.3% and achieves an on/off current ratio exceeding 135,000.
Researchers found that different types of tea create kombuchas with distinct chemical profiles, flavors, and aromas. Green and oolong teas produced kombuchas with high antioxidant activity, while black and pu-erh teas resulted in earthier flavors.
Researchers developed a senolytic therapy using dasatinib and quercetin, which preserved disc structure and reduced inflammation, highlighting JUN signaling as a key pathway. This preclinical study provides evidence for a potential therapeutic strategy to slow disease progression in individuals with genetic susceptibility.
A study reveals that TREM2+ macrophages directly recognize candidalysin, a toxin secreted by Candida albicans, to initiate an immune response. This recognition leads to the activation of key immune cells and the production of pro-inflammatory cytokines, ultimately protecting against fungal infection.
A report by the European Society of Cardiology advocates for dedicated women's heart centers to improve diagnosis and treatment of cardiovascular disease in women. These centers can enhance quality of life, reduce symptoms, and increase survival rates for women with cardiovascular disease.
Chronic liver disease is a significant burden in Europe, with millions affected by premature illness and death. The Series calls for coordinated prevention, earlier detection, care pathways, and non-judgemental approaches to connect liver health with other chronic conditions.
Patients with employer-sponsored insurance may benefit from using direct-to-consumer pharmacies for high-cost generics, with savings ranging from 80% to nearly 100%. This strategy is particularly recommended for disease areas with high cost sharing, such as oncology and psychiatry.
A team of researchers at Kyoto University has reconstructed the family tree of blood cells over a 700-million-year span, revealing their evolutionary history. They found that early blood cells emerged around the same time as multicellular animals and were macrophage-like.
Researchers found that smaller tetraploid cancer cells are more aggressive and tumorigenic, associated with worse prognosis and lower survival rates in several cancer types. This discovery challenges the conventional understanding of tetraploidy's role in cancer progression.
A new international psychology study found that people frequently fail to notice the absence of women, colleagues of color, or men in various settings. Participants were more likely to notice the presence of a single minority group member than the complete absence of any group.
A study by Jan Schmutz and Andrea Cantisani found that frequent contact didn't necessarily lead to positive social relationships. In fact, increased proximity was linked to conflict, mistrust, and reduced performance. The researchers also observed subgroups forming within the team based on language or nationality.
Researchers found that using transcutaneous auricular vagus nerve stimulation (taVNS) while moving activates specific brain areas involved in motor systems. This suggests that taVNS may be a useful treatment intervention for mobility issues, potentially leading to improved motor performance.
Scientists at the University of Edinburgh have developed a pioneering cell therapy that tackles scarred tissue and restores liver function. The treatment shows promise as a potential alternative to liver transplants for those in end-stage liver disease, with 70% of patients living without needing a transplant after four years.
This study investigates the role of YTHDF1 in nonalcoholic fatty liver disease (NAFLD) and its epitranscriptomic control of NUPR1. The researchers found that YTHDF1 promotes hepatic steatosis by enhancing NUPR1 mRNA stability, leading to elevated NUPR1 protein levels and exacerbating NAFLD progression.
Research reveals tropical cyclones contribute to ocean carbon outgassing but its role is decreasing due to global warming. If emissions remain high, they may reverse to enhancing ocean carbon uptake, accelerating ocean acidification.
Researchers analyzed 4,344 unpublished records from 1980 to 2025, identifying 302 amphipod species across the Adriatic, Tyrrhenian, and Ionian Seas. The study highlights the importance of amphipods in marine ecosystems, playing a key role in nutrient recycling and food webs.
A new study led by the University of Michigan found that drought conditions in the Southwest have reduced the suitable habitat for herbivores, omnivores, and carnivores by at least 10%. The analysis of 12 years of data from GPS collars on mule deer, black bears, and cougars showed that drought is negatively impacting life across Utah a...
A recent study led by UCL researchers found that cooperative societies of tropical paper wasps can survive fierce leadership battles due to individual wasps that pick up the slack. These compensators avoid conflict and increase their investment in essential tasks like foraging and brood care, maintaining societal function.
A recent study has identified five distinct species of pit vipers in the Himalayan region, including three new to science. The research combined fresh and historical DNA data with morphological and skeletal analysis, revealing deep evolutionary lineages and distinct ecological characteristics.
A newly-discovered blue octopus from the Galapagos Islands has been identified as Microeledone galapagensis, and its unique features were revealed through micro CT scans. The species is the first new octopus species led by curator emerita Janet Voight in her four-decade career.
Dr. Harding's research shows that laughter can help children handle stress, develop emotional intelligence, and improve memory. Laughter also fosters social skills and strengthens the immune system, making it an essential component of early childhood development.
A study has mapped the development of lung damage in young children with cystic fibrosis, revealing that immune abnormalities begin early in life and persist despite current treatments. The research found that targeted anti-inflammatory therapies may be necessary alongside existing medications to prevent permanent lung damage.
Researchers at Tokyo Metropolitan University have identified a unique type of heat wave in Japan, known as 'moist heat waves,' which are accompanied by tropical cyclones and high humidity. These heat waves account for a quarter of the days surveyed and pose significant hazards due to extreme temperatures and torrential rain.
New research reveals a recent increase in sightings of blue and fin whales in the southeastern Atlantic, suggesting resilience after decades of commercial whaling. However, both species remain vulnerable to human pressures such as climate change and pollution, highlighting the need for continued conservation efforts.
A new framework maps Europe's climate-smart rewilding potential, highlighting regional strengths in Eastern and Southern Europe. The approach balances ecosystem restoration with climate mitigation and adaptation, offering opportunities for diverse regions to contribute.
Researchers used DNA metabarcoding to analyze benthic macroinvertebrates across 18 Ontario streams, detecting far greater biodiversity than traditional methods. The study found that DNA-based biomonitoring can reveal ecological patterns and changes linked to agriculture, water quality, and land use.
Researchers at Worcester Polytechnic Institute develop a one-step molten salt upcycling process to transform spent nickel cathodes into high-performance materials for next-generation lithium-ion batteries. This approach reduces recycling costs and energy demands while increasing the value of recovered materials.
A new study by the University of Ottawa suggests that a tiny molecule, methylglyoxal, plays a major role in triggering neurological disorders after a heart attack. The molecule accumulates in the brain following a heart attack and is linked to depression, anxiety, and cognitive decline.
Scientists discovered a molecular switch that enables plants to form partnerships with soil fungi even when sufficient phosphate is available, offering a potential solution to reducing fertilizer use. The discovery could enable targeted manipulation of mycorrhization in crop plants using modern breeding methods.
Researchers at CNIC identify mitochondrial complex I as a key checkpoint for dendritic cell activation. Restoring its function restores immune responses against viruses and tumors. The study paves the way for new strategies in vaccines and cancer immunotherapies.
Scientists have demonstrated that megalibraries can design materials with specific properties, accelerating the traditional trial-and-error approach to rapidly designing and testing materials. The platform generates vast datasets needed to train AI systems to discover next-generation materials.
A Tulane University study found that long-term antiretroviral treatments did not fully restore key immune functions to protect and repair the gut lining in nonhuman primates with SIV. The researchers discovered that diet-derived compounds from vegetables like broccoli and cabbage may support immune activity involved in gut repair.
A new oral antiviral drug candidate, GHP-88310, has been identified for the treatment of orthoparamyxovirus diseases such as measles and Croup syndrome. The compound is effective against a broad spectrum of viruses when taken once daily by mouth and has excellent tolerability.
Researchers at the University of Cincinnati's Center for Advanced Structural Biology have visualized the structure of iRhom1 bound to the ADAM17 enzyme, shedding light on its role in regulating cell surface protein targets. This breakthrough discovery may lead to new therapeutic strategies for treating chronic inflammatory diseases.
Researchers discover that kinases play a crucial role in moving cholesterol to activate a growth pathway in aggressive cancers. Without these enzymes, cancer cells are blocked from fueling tumor growth. The study highlights the importance of targeting lipid enzymes as a potential treatment strategy for cancers with TP53 mutations.
The 4th International Conference on Carbon Dioxide Removal will bring together global experts to share the latest research and foster cross-disciplinary collaboration. The conference aims to advance resilient CDR strategies grounded in robust scientific evidence.
A recent study combines quantum physics with a carefully designed metasurface to develop a compact terahertz detector that improves how THz radiation is captured and converted into an electrical signal. The device achieves significant sensitivity gains, up to 20-fold improvement over previously demonstrated photoelectric detectors.
A single dose of psilocybin reduces nerve pain for several weeks and makes gabapentin work more effectively. The study found that psilocybin resets the brain's pain networks, making existing treatments significantly more effective.
A new study by international researchers suggests that massive Atlantic seaweed blooms could be harnessed for climate solutions such as marine carbon dioxide removal and biofuel production. The vast blooms of Sargassum are not only likely to persist, but may be predictable, with predictive capability reducing uncertainty about the futu...
A Virginia Tech study found that AI image generators consistently produce more realistic and recognizable images of larger metropolitan areas than smaller towns. The research raises questions about how generative artificial intelligence tools portray places and whose communities are most visible online.
A new study reveals that metabolic dysfunction in offspring is caused by excess microRNA in sperm from obese fathers. After weight loss, these molecular marks disappear, and offspring develop normally. Research suggests that interventions promoting health and longevity may trigger an increase in this enzyme expression.
Scientists at Penn State and UChicago uncover the physical principles of superconductivity in diamond, enabling multiple functions on one quantum chip. The discovery offers a potential roadmap for improving the performance and temperature range of future quantum devices.
Research reveals that gay dating apps during travel can bring excitement and connection but also lead to emotional exhaustion and catfishing. Participants describe using apps to cope with boredom, insecurity, and the emotional intensity of unfamiliar places.
Kate Flewelling, director of the Alumni Medical Library at Boston University Medical Campus, has been honored with the President's Award from the Medical Library Association. The award recognizes her dedication to improving the lives and careers of health sciences librarians through service and leadership.
A new Frontiers in Science article explores how AI can accelerate scientific discovery in soil science by creating digital soil twins and trialing climate adaptation strategies. Researchers will discuss the potential of multi-agent AI systems to enable autonomous hypothesis generation, experimental design and data analysis during a fre...
Researchers have made significant breakthroughs in nuclear medicine, with studies revealing uneven radiation doses in tiny kidney structures, improving survival rates for prostate cancer patients through targeted radiation therapy, and developing a new PET imaging approach to detect abdominal cancer spread. These advancements aim to im...
Researchers established the first complete, exactly solvable framework that unifies all seven fundamental localization phases in quasiperiodic systems. The framework also points to a concrete route for realizing predicted physics with ultracold atoms, offering new opportunities for experimental realization.
A recent study analyzing nearly 800,000 fashion images reveals that while representation has broadened, the typical female model body has remained remarkably stable. Diversity is primarily concentrated in a small number of models at the extremes rather than through a shift in the norm itself.
A novel software-defined networks (SDN) intelligent routing architecture based on photonic spiking reinforcement learning is proposed, providing a low-latency, high-efficiency, and adaptive intelligent routing system. The system outperforms traditional routing algorithms in data centers, 6G, and satellite networks.