Researchers propose a novel molecular system to address surface defects and suppress ion migration in perovskite solar cells. The dual-functional molecule, [12]-C-4POR, traps specific ions with its cyclic binding sites, enhancing device stability and performance.
A study from the Ragon Institute reveals how a live bacterial therapy works to prevent recurrent bacterial vaginosis (BV) and why it works better for some women than others. The therapy, LACTIN-V, was found to successfully colonize the beneficial bacterium Lactobacillus crispatus in 30% of women, leading to improved vaginal health.
Researchers developed an innovative colloidal chemistry strategy to enhance the performance of all-perovskite tandem solar cells, achieving a power conversion efficiency of 29.76%. The unified carboxylate-based modulator system regulates nucleation dynamics, suppressing phase segregation and promoting uniform crystal growth.
Researchers at Northumbria University used the James Webb Space Telescope to map Saturn's auroral region, revealing a complex pattern of heating and cooling. The findings show that Saturn's aurora is not just a visual display but actively heats its atmosphere, driving winds that generate electrical currents.
A York University-led study finds that higher education is strongly associated with cultural values typical of 'WEIRD' societies. The research analyzed data from nearly 270,000 people across 95 countries and found that highly-educated individuals were significantly closer to Western cultural norms.
The FDA has approved a gene therapy for severe leukocyte adhesion deficiency-I, a rare genetic condition that affects one in a million children globally. The therapy, Kresladi, has been shown to significantly reduce severe infections and improve immune function in treated patients.
A previously unknown harvestman species has been found in Eocene amber deposits in Ukraine and the Baltic region. The fossil, named Balticolasma wunderlichi, reveals a highly ornamented body with lattice-like appendages and complex mouthparts, challenging current knowledge of species distribution.
Researchers at Memorial Sloan Kettering Cancer Center discovered that skin stem cells possess a remarkable form of inflammatory memory that can last over a year. This finding has implications for understanding how repeated inflammation affects skin aging and disease susceptibility. The study used MSK-IMPACT, a tumor sequencing test, to...
Higher left atrial end-systolic dimension and left ventricular mass are associated with a higher risk of adverse health outcomes, including mortality, cardiovascular disease, dementia, hypertension, diabetes, and chronic kidney disease. Lifestyle changes and heart-healthy habits can help maintain optimal values of these measurements.
Researchers have developed a lead-free quantum dot glass that improves photoluminescent performance and stability, achieving a quantum yield of 43.45% after 450 days in hot and humid conditions. The material enables durable anti-counterfeiting optical codes and reliable solid-state lighting components.
A new study proposes a learning architecture that integrates educational philosophy with AI-driven design, aiming to transform assessment into an ongoing process of reflection. The system prioritizes human judgment and interpretation over standardized metrics, enabling educators to build adaptive and interpretable feedback systems.
Researchers have identified TIE2 as a crucial link between two signaling pathways that drive the growth of blood vessel abnormalities in the brain. Inhibiting TIE2 with a small drug called rebastinib may provide an endothelial cell-centered approach to prevent CCMs, which can cause brain hemorrhages and seizures.
The BiliSeq test detected approximately 82% of bile duct cancers, compared to 44% with pathology alone, and increased cancer detection to nearly 90% when combined with pathology. This improved accuracy enables physicians to provide more personalized medicine and treatment options for patients.
New research from the University of East London suggests that machine learning can improve the accuracy and nuance of personality tests like DISC assessment. Using over 1,000 participants, researchers achieved accuracy rates of over 93% in predicting personality types and identified four clear clusters with subtle overlaps.
A comparative study examines the effectiveness of guselkumab versus golimumab in treating moderately to severely active ulcerative colitis. The results indicate that guselkumab may improve morbidity and health-related quality of life, but there is no clinically relevant benefit compared to standard treatment.
The International Centre for UNESCO Associated Schools Network (ICUA) will host the UNESCO ASPnet Global Meeting in Sanya, Hainan Province, highlighting China's advances in education. The meeting focuses on peer learning and field-tested solutions to transform education globally.
A review highlights the importance of healthy lifestyles in reducing the risk of cardiovascular disease and type 2 diabetes. Adhering to optimal lifestyle factors, such as a heart-healthy diet, regular physical activity, and adequate sleep, can dramatically lower disease incidence.
A new study in China finds that onetime lowdose computed tomography (LDCT) screening can significantly reduce lung cancer mortality in a non–risk based population, including individuals with no smoking history. The findings support reconsideration of current eligibility criteria.
Researchers at Dalian Institute of Chemical Physics introduced a novel method to stabilize Fe oxide catalysts using ceria surface overlayers, promoting the formation of active Fe3O4 and suppressing over-reduction. This approach enhances stability compared to traditional industrial catalysts.
A team of Chinese researchers found that façade-integrated photovoltaics can generate substantial electricity while reducing cooling demand, thereby reducing carbon emissions and improving urban climate adaptation. FIPV adoption could lead to meaningful economic and climate gains worldwide.
The UNESCO ASPnet Global National Coordinators Meeting will bring together educators and experts to discuss pressing global education priorities. The meeting aims to enhance national coordinators' operational capacity and scale effective education innovations through peer learning and practical empowerment.
A team of researchers has proposed an integrated detection system for high-precision atmospheric characterization and resource utilization on Venus. The system combines gas filtration, enrichment, and spectroscopic analysis to detect trace gases and their isotopic signatures, overcoming the challenges posed by sulfuric acid clouds.
Researchers found that two species of ticks, Gulf Coast and lone star, can live at least one week and up to three weeks on hard-surface and carpeted floors. The study emphasizes the importance of taking protective measures to prevent tick bites.
Research finds global hotspots of plant invasion risk will shift geographically, with temperate regions facing increasing risks, while subtropical areas may see declining risks. The study projects significant changes in alien species composition and expected impacts on native biota and human well-being.
A study found significant CD39 expression on CD4+ T-cells in HIV/HCV coinfected patients, with a negative correlation between CD39 positivity and pro-inflammatory chemokines. This suggests that CD39-positive T-cells play a role in controlling purinergic signaling in these patients.
Researchers developed a machine learning model to predict 28-day mortality in patients with sepsis complicated by acute respiratory failure. The model demonstrated strong discrimination for predicting mortality, with key variables including oxygenation indices, serum albumin levels, and disease severity scores.
The new guideline focuses on lowering elevated LDL cholesterol levels and emphasizes the importance of earlier screenings, especially for those with a family history of heart disease. It also encourages more personalized risk estimations to support shared decision-making between clinicians and patients.
Researchers at Kobe University have discovered a region beneath the Kikai caldera in Japan that is filled with magma, which they believe is newly injected magma. This finding allows them to propose a general model for how magma reservoirs under caldera volcanoes refill, potentially improving our ability to predict future giant eruptions.
A new tool developed by UCL researchers can identify diet and nutrition misinformation, as well as its risk for potential harm. The tool assesses the content's risk based on factors like inaccuracy, hazardous omissions, and manipulative framing.
A major population study found that delirium during hospital admission is associated with a markedly increased likelihood of future dementia across all levels of pre-existing health. In individuals with few long-term conditions, delirium was linked to a three-fold higher risk of developing dementia and substantially increased mortality.
Researchers at Nagoya University found that a brief spike in testosterone after birth causes muscle-wasting disease to develop decades later. Treating the disease at birth significantly reduced nerve cell breakdown in adult mice.
The BMW Group Change Maker Fellowship supports future leaders in shaping digital transformation, combining technology with leadership skills. Candidates from countries with BMW IT hubs are eligible, with a focus on quantitative or tech-focused backgrounds.
TUM researchers have identified the microscopic causes of instability in perovskite solar cells and developed a strategy to prevent degradation through temperature swings. They discovered that a 'burn-in' phase triggers early loss of relative performance, but using special organic molecules as spacers can stabilize the material.
Researchers surveyed schoolchildren about play and identified universal elements that contribute to 'good' play. High levels of accessibility and a sense of 'play feeling' were often present in enjoyable experiences, while factors like social inclusion, imagination, and transgression also played a role.
A team of researchers, led by Felicity Newell, tracked over 8,000 birds in Peru's cloud forests and found that breeding times vary significantly due to changing environmental conditions. The results suggest a more complex response to climate change than previously thought.
Researchers at Singapore Management University have developed VISTA, an AI system that embeds socially grounded values into the decision-making process of large language models. The system aims to ensure AI trustworthiness and accountability by monitoring and regulating AI behavior in real-time.
MIT researchers create an implantable device containing insulin-producing cells that survive in the body for at least 90 days, producing enough insulin to regulate blood sugar levels. The device's improved oxygen generator and electronics enable longer cell lifespan and increased insulin production.
Researchers at Curtin University discovered how ancient ichthyosaur fossils formed in oxygen-free ocean floor settings. Anaerobic microbes triggered chemical reactions that caused minerals to form inside the bones, preserving them three-dimensionally.
A transcription factor phosphorylation switch, OsAHL23, dynamically balances immune responses and growth in rice. The switch is precisely controlled by the kinase OsMPK5 and phosphatase PP2A-A.
Kennesaw State University has joined the ORAU research consortium, partnering with government agencies, industry, and academia to connect researchers and students with scientific opportunities. This move reinforces KSU's commitment to advancing research productivity, innovation, and student support.
A comprehensive review of BNCT suggests it can precisely target and destroy cancer cells while sparing healthy tissue. The therapy has shown promising results in extending overall survival and improving quality of life for patients with various types of malignant tumors.
A new article by G. Williamson McDiarmid argues that the traditional model of teacher professional development is failing educators, pointing to micro-credentials as a compelling alternative. Micro-credentials offer teachers greater autonomy and control over their learning, which is associated with improved job satisfaction.
Researchers create electrochemical process that converts lignin into aromatics and cyclohexene-based compounds without external hydrogen, upgrading it into useful chemical precursors. The study demonstrates high selectivity and efficiency in the conversion of recalcitrant ether bonds in lignin.
A new zebrafish study sheds light on why haploid fish embryos often fail to survive normal development. Researchers identified 13 key genes associated with abnormal development, highlighting disruptions in FGF and Wnt signaling pathways, mitochondrial translation, ion transport, and cell-cycle regulation.
A study published in PNAS found that the human brain's resilience process doesn't peak immediately after a stressful event; instead, it manifests in a distinct 'resilience window' about an hour later. This delayed neural shift distinguishes resilient individuals and offers a new time-target for interventions.
The American Heart Association has awarded 32 financial grants to promote CPR training and education in 20 states. These grants will help create safer school environments and empower students to learn lifesaving skills. The long-term goal is to ensure anyone can perform CPR in the face of a cardiac emergency.
Global maternal deaths fell to 240,000 in 2023, but progress has slowed in recent years and remains uneven across countries. Improvements in access to quality care could substantially reduce mortality, particularly in high-burden regions.
The University of Chicago and IDefine are partnering to develop a potential therapeutic strategy for Kleefstra syndrome, a rare disorder caused by EHMT1 gene haploinsufficiency. The project aims to restore essential protein levels in the brain using programmable RNA therapy.
A new analysis of existing studies found that nicotine e-cigarettes consistently help adults quit smoking, with quit rates approximately 20-40% higher than traditional nicotine replacement therapies. However, the effectiveness of e-cigarettes may be linked to sensory cues beyond just nicotine delivery.
A new study reveals that excess weight can physically enlarge organs, creating more opportunities for cancer to take hold. The study found that organs grew larger as body weight increased, with the liver growing by 12%, kidneys by 9%, and pancreas by 7% for every 5-point increase in BMI.
A new overview of systematic reviews found that nicotine-containing e-cigarettes are more effective for smoking cessation than other interventions. The review also identified gaps in current evidence, including the need for high-quality studies on cytisine and bupropion.
A study found that tumor DNA in patients' blood can predict whether breast cancer will return, especially after neoadjuvant treatment. Patients with detectable DNA at the end of treatment were 3.5 times more likely to relapse during follow-up.
The US Nature Assessment Report documents human impact on nature, including resource extraction and habitat loss, but also shows restoration and Indigenous stewardship approaches can help turn things around. The report highlights the importance of farmer involvement in protecting ecosystems and preserving biodiversity.
Wild grey squirrels show a preference for almonds over pumpkin seeds, even when they require a longer climb to reach. This suggests that animals may benefit from waiting or working harder for a better outcome in natural decision-making scenarios.
A new study reveals that freeze-thaw cycles can dramatically improve biochar's ability to trap toxic arsenic in contaminated soils. The research found that freezing and thawing fundamentally reshapes how biochar interacts with soil at microscopic scales, creating stronger connections between biochar particles and soil minerals.
Researchers have reported early, reassuring results from the LORD trial on active surveillance for low-risk DCIS. The study found that patients with active surveillance did not experience worse early outcomes compared to those who underwent immediate surgery, and that many chose active surveillance over surgery.
The Critical Path Institute has launched a global, multi-stakeholder initiative to enable scalable development of advanced therapies for small patient populations. The 'One to Millions' program advances regulatory frameworks and leverages data platforms to support evidence generation and development pathways.
Researchers at UC Irvine have identified LENG8 as a crucial regulator of RNA quality control, enabling cells to retain or degrade specific RNAs. This discovery sheds light on the mechanisms underlying cellular processes such as gene expression and translation.
A new field study reveals that biochar can significantly restore soil health and nitrogen availability in forests affected by acid rain. Biochar triggers major biological changes in the soil, enhancing microbial biomass and increasing nitrogen use efficiency.
Researchers have developed experimental compounds that block flu viruses by locking onto their surface enzyme, potentially improving treatments and pandemic preparedness. The new approach shows promise in stopping common types of flu virus, including H3N2 and bird flu strains.