A qualitative study found that family physicians in Ontario left comprehensive care due to unsustainable finances, heavy workloads and lack of support. Policymakers must address these concerns to retain practicing family physicians and improve access to primary care.
A study compared four approaches to supporting opioid deprescribing in primary care clinics, finding that clinics with both clinic workflow support and prescriber coaching had the largest reduction in average opioid dose. Clinics that received education alone showed significant increases in urine drug testing and treatment agreements.
A randomized controlled trial found that contingent discount financial incentives on medication expenses can improve glycemic control and encourage engagement with ongoing monitoring among patients with poorly controlled type 2 diabetes. After six months, the intervention group showed greater improvements in long-term blood sugar level...
In Ontario, primary care home visits for adults aged 65 years and older decreased by nearly 30% after a 2019 policy change and the COVID-19 pandemic. Nonpalliative visits declined more than palliative ones, which showed growth after 2020.
Alcohol screening increased from 61% to 81%, and intervention among positive screens rose from 22% to 67%. Practices improved documentation of pregnancy intention, using the AUDIT-C tool more frequently. This approach empowers local staff to lead care improvement efforts.
A new study has created a comprehensive atlas of lysosomal proteins in the brain, shedding light on the functions and dysfunctions of these cellular components. The data, which includes 790 proteins associated with lysosomes, could help scientists better understand neurodegenerative diseases such as Alzheimer's and Parkinson's.
A study found that chronic stress and inflammation contribute to elevated mortality risk among Black Americans, with approximately half of the disparity attributed to these factors. The research suggests policy efforts to address structural racism and stress exposure can help minimize health risks.
A family medicine interdisciplinary team improved hepatitis C virus treatment outcomes by streamlining medication access and reducing administrative burdens. The team's strategy, implemented at an urban clinic in Ohio, resulted in a significant reduction of treatment delays from over 6 months to under 2 months.
A new set of guidelines provides veterinarians and pet owners with a clear approach to diagnose and monitor canine cognitive dysfunction syndrome (CCDS), also known as canine dementia. The guidelines outline key signs, diagnostic levels, and stages of disease severity to support care decisions.
A new produce prescription program improved nutrition security and household food security for Medicaid patients with diabetes or prediabetes. Meanwhile, contingent discounts on medication expenses were found to support better glycemic control in socioeconomically disadvantaged patients with uncontrolled type 2 diabetes.
The study confirms that ancient lichens played a key role in forming the first soils and structuring terrestrial ecosystems. Researchers identified the presence of chitin, nitrogen compounds, and calcium microparticles compatible with modern lichen minerals.
A UCLA-led team has discovered a novel mechanism of kidney stone formation involving bacteria, challenging the long-held assumption that stones develop solely through chemical and physical processes.
Researchers found that people experiencing everyday discrimination have elevated levels of "exhausted" white blood cells, indicating chronic stress may hamper the immune system. This study suggests social experiences like discrimination shape immune health at the cellular level and contribute to biological aging.
A WVU research team is working to restore vision in people with inherited blindness due to genetic mutations in the Prominin1 gene. The team has observed encouraging early results using a mouse model and plans to investigate the therapy's effectiveness beyond initial restoration.
A new study reveals that cougars' dietary changes to smaller prey help them avoid wolf encounters and reduce competition. Researchers found that cougars tend to avoid areas where wolves have made kills and stay close to escape terrain.
A new AI-powered app, DinoTracker, uses advanced algorithms to analyze dinosaur footprints and predict their makers. The system achieved 90% agreement with human expert classifications, revealing surprising similarities between ancient dinosaur tracks and modern birds.
A new study from Harvard found that North Atlantic pilot whales have 60% lower concentrations of per- and polyfluoroalkyl substances (PFAS) in their bodies since the phaseout of these chemicals. The researchers measured bulk organofluorine levels as a proxy for total PFAS concentrations, including newer types of PFAS.
A survey of 438 adults who used cannabis in the past year found that nearly 56% also drank alcoholic beverages, with users more likely to substitute cannabis for alcohol. Respondents reported consuming fewer alcoholic drinks and binge drinking less frequently after starting cannabis beverages.
A new remote sensing model, developed by SERIDA, identifies areas where fossorial water voles are present or could expand with high accuracy (97%). The tool helps public administrations plan early warning systems and resource management for pest vole populations.
The State of Open Data report shows open data has become embedded into research practice with FAIR awareness widely recognized. Researchers need systems that reward openness and workflows that make sharing effortless to sustain progress.
A new study from the University of Victoria found that higher insulin levels at age 47 predicted younger onsets of hot flashes and night sweats. Insulin may be a stronger predictor of hot flashes when taking other metabolic variables into account, while body mass index (BMI) appeared more closely associated with estrogen level changes.
A new study shows that people who perceive artificial intelligence as replacing human labor are more dissatisfied with democracy and less politically engaged. This perception is linked to a causal decline in democratic legitimacy, even if AI has only had a limited impact on the jobs market.
Researchers have found that nanoplastics interact with environmental microbes, strengthening bacteria and antimicrobial-resistant pathogens. This can lead to challenges for water treatment and distribution systems. More research is needed to understand the molecular mechanisms underlying these interactions.
The University of Phoenix College of Doctoral Studies has released a new white paper highlighting the challenges faced by women who balance caregiving, work, and learning. The paper calls on institutions to build life-aligned learning models that reduce cognitive load and expand opportunity for 'sandwich generation' moms.
The new feature in Sage Policy Profiles matches researchers with live policy engagement opportunities based on their research, biography, and countries of interest. Over 26,000 researchers have used the tool to discover their policy impact since its launch.
Researchers propose a new design principle for QM/MM simulations, enabling the objective and automatic determination of the quantum-mechanical region based on electronic-state changes. This approach addresses long-standing challenges in multiscale molecular simulations, demonstrating consistent applicability across different systems.
Researchers developed a miniaturized solid oxide fuel cell microreactor to power edge devices like drones and AI hardware with high energy density. The device features an innovative structural design with thermal insulation and a multilayered insulation system, solving thermal stress and safety concerns.
Vertebral fractures are a devastating complication of advanced kidney disease, associated with increased risk of further fractures and cardiovascular events. The first global consensus statement offers practical recommendations for clinicians to identify and manage vertebral fractures in patients with chronic kidney disease stages G4–G5D.
A recent study by the MarPITIUS25 project reveals that Ibiza's coastline has lower biodiversity, biomass, and adult fish populations compared to other Mediterranean locations. The study highlights the impact of environmental pressures such as wastewater discharges, desalination plants, microplastics, and intense tourism on the ecosystem.
Researchers developed a novel tool, CytoTape, to record temporal cell activities in situ along a flexible intracellular protein fiber. This technology enables scientists to view interactions on a large scale and over long periods of time, breaking through the tradeoff between resolution and scale.
Researchers at the University of Cambridge have developed an energy-efficient reactor that captures and recycles methane to produce clean hydrogen and high-performance carbon nanotubes. The process uses a multi-pass floating catalyst chemical vapour deposition reactor with process gas recycling, significantly reducing energy requirements.
A new study from Nationwide Children's Hospital finds that similar to older children and adults, about one fourth of children under six years old who experience a concussion will develop prolonged symptoms. Younger children are more likely to sustain brain injuries due to their size differences and weaker muscles.
Scientists from the University of Malaga have optimized wastewater use for green hydrogen production through artificial intelligence, improving its efficiency and sustainability. The study used machine learning to fine-tune the process, reducing energy consumption and organic waste.
Researchers compared three methods to measure surface currents over large areas, identifying an ideal drone-based technique that uses short aerial videos and mathematical analysis of wave patterns to determine current speed and path. This approach offers several advantages, including reduced costs and ease of deployment.
Researchers have designed a prototype powder that activates to whiten and repair teeth, promoting oral health. The system uses the piezoelectric effect to generate ROS, killing bacteria and reducing inflammation in lab demonstrations.
Researchers developed a first-of-its-kind probe to track a fetus's vital signs in utero during surgery. The soft, flexible robotic probe provides accurate and precise measurements of heart rate, blood oxygen levels, and temperature, enabling faster interventions in case complications arise.
A newly uncovered Roman sanctuary in Frankfurt's Nida district will be studied for its significance in Roman Germania. The site features 11 stone buildings, 70 shafts, and 10 pits used for ritual depositions, yielding ceramic vessels and animal remains.
Researchers found that six species exhibited little to no evidence of phylosymbiosis, while five closely related bovids showed patterns consistent with the concept. Drier environments may reveal phylosymbiosis due to reduced microbial diversity.
Cardiac MRI offers comparable diagnostic accuracy to SPECT for coronary heart disease (CHD), but without exposing patients to radiation. This expansion of diagnostic options allows for more differentiated and less invasive testing.
The JAMA Editorial Fellowship Program has selected ten new fellows, including physicians and nurses from diverse backgrounds, to learn about editorial decision-making and enhance scientific communication skills. Fellows will observe the peer-review process firsthand and bring their unique expertise to the table.
Researchers at the University of Michigan developed a pair of sensors that can detect ice and freezing rain, alerting pilots to potential hazards and reducing crashes. The sensors use microwaves and lasers to detect ice on planes and roads, potentially saving lives by slowing down drivers and preventing accidents.
A recent study found that adding manganese to soil can lower plant-available nitrogen, reducing nitrous oxide emissions and nitrate leaching into waterways. Manganese also reduced the expression of genes involved in nitrogen cycling.
A Texas A&M University study has identified a mouse strain that responds to a viral infection in a way similar to humans with ALS. The researchers found that the initial viral infection triggers lasting damage to the spinal cord and its nerves and muscles, even after the virus is cleared.
A University of Oklahoma researcher has been awarded a competitive NIH grant to advance tribally defined genomic research approaches. The project, called Partnerships for Indigenous-led ELSI Research (PIER), will strengthen meaningful collaboration with Indigenous communities and promote Indigenous-driven approaches to genomic research.
A living biosensor made of bacteria detects acetic acid levels in wine, alerting wineries to potential spoilage. The sensor works in real-time and can detect volatile acetic acid in the air above wine bottles, enabling early intervention before damage is done.
A pilot study found that long-term exposure to higher pollen levels leads to worse symptoms and quality of life for patients with chronic rhinosinusitis. Higher ragweed pollen exposure correlated with worse Sino-Nasal Outcome Test scores.
A recent study found that the proposed 'Nutrition Info Box' label works best for consumers with higher nutrition literacy, but may not be effective for those with lower literacy levels. The study suggests that a different label design could help bridge this gap and support healthier eating habits.
Researchers from the University of Kansas discovered that taller, leaner athletes with improved jumping ability generate faster club head speeds. The study developed golf-specific load velocity profiles to help athletes and coaches develop plans for improvement, focusing on exercises like squats and building lean mass.
Researchers developed an AI approach that enables knowledge transfer across species boundaries, allowing AI to learn from animal image data and apply it to human tissue. The method, called xeno-learning, overcomes the need for large amounts of annotated human image data, making surgical procedures safer and more precise.
Researchers developed an English version of a Japanese oral health screening tool to identify age-related decline in oral and swallowing function among U.S. older adults. The adapted Oral Frailty Index-8 (OFI-8) assesses eight key areas, with a score of four or more indicating high risk of oral frailty and warrants further evaluation.
Pensoft has welcomed the Swiss Journal of Palaeontology (SJP) and Swiss Journal of Geosciences (SJG) to its portfolio. Both journals have transitioned to open-access models, leveraging Pensoft's ARPHA publishing platform for streamlined processes and increased visibility.
A study aboard the International Space Station reveals how microgravity affects microbial metabolism and limits the efficiency of biological manufacturing processes. Microbes produce less melanin due to impaired transport and utilization of tyrosine, a molecular precursor required for melanin synthesis.
Researchers at the University of Jena used advanced imaging techniques to examine two fossilized animal inclusions in Goethe's amber collection, revealing a previously unknown species of ant. The ant, named Ctenobethylus goepperti, is believed to have built large nests in trees and its lifestyle is compared to that of modern ants.
Researchers will create a new modality called Phase Change Ultrasound Lymphograph to super-resolution map lymphatic structures, providing quantitative information on anatomy and function. The device aims to screen for lymphatic abnormalities and guide treatment decisions.
A new study by IIASA and UN-Habitat finds that citizen science can strengthen urban sustainability monitoring, particularly for issues like air quality and community wellbeing. The analysis reveals that many indicators remain incomplete and are reported mainly at national level.
A study from Linköping University finds that locally produced green hydrogen is cheaper to produce at southern latitudes due to favorable solar energy conditions. The cost of green hydrogen production varies across European countries, with Nordic nations facing higher costs due to lack of sunlight.
A large-scale genetic study has identified 34 genetic regions associated with the risk of allergic conjunctivitis, revealing a complex interplay between genes and environmental factors. The study found that genes influence the severity and recurrence of symptoms, but do not cause the condition alone.
Researchers investigated the therapeutic potential and molecular mechanisms of oxytocin in metabolic dysfunction-associated steatotic liver disease (MASLD). Oxytocin attenuates lipid accumulation and accelerates lipid metabolism by regulating the AMPK/SREBP1c/FAS axis.
Researchers discovered that hibernating Syrian hamsters preserve muscle mass by suppressing the generation and regeneration of muscle tissue. The study found that skeletal muscle stem cells have altered gene expression during hibernation, which leads to their maintenance, but suppresses regenerative activity.
Researchers found that higher testosterone levels reduced risk, while increased estradiol levels increased cardiovascular risk in male participants. In contrast, women with diabetes showed no significant link between hormone levels and cardiovascular outcomes.