A new study found that a single toxic fungicide exposure during pregnancy can increase the risk of disease for 20 subsequent generations, with inherited health problems worsening over time. The study suggests that epigenetic disease inheritance could help explain rising chronic disease rates in humans.
A new study has found that astrocytes are crucial for aversive memory, including learning what to fear and recalling memories. The findings challenge long-held assumptions about fear memory and suggest new treatment approaches for disorders like post-traumatic stress disorder.
A new study found that social media use, particularly exposure to muscularity-focused content and body comparisons, is strongly associated with increased intentions to use anabolic-androgenic steroids. Young men who frequently view muscular bodies or advertisements promoting muscle-building supplements also report stronger intentions.
The Milken Institute and Ann Theodore Foundation have launched a new funding program, ATF-SIM, to support a Phase 2 clinical trial assessing the effectiveness of mTOR inhibitors in treating cutaneous sarcoidosis. The grant will award up to $575,000 to researchers to design and conduct the trial.
A new study suggests that switching to a second treatment while a tumor is still responding to the first may improve cure rates. The 'kick it while it's down' approach targets small tumors and has been shown to be successful in other contexts, such as combatting antibiotic resistance.
Scientists at Cincinnati Children's Hospital Medical Center have discovered a way to reduce the risk of a lethal side effect in cancer patients treated with immune checkpoint inhibitors. By targeting CD8 T cell-derived tumor necrosis factor, they found that blocking TNF signaling can prevent inflammatory cycle in the heart.
A large new study published in JAMA Health Forum found that past-year cannabis use during adolescence is associated with a significantly higher risk of incident psychotic, bipolar, depressive, and anxiety disorders. Cannabis use preceded psychiatric diagnoses by an average of 1.7 to 2.3 years.
A study analyzing data from 44,000 adults found that those with intellectual and developmental disabilities experience substantially higher rates of anxiety and depression. The study also highlights significant healthcare treatment and access barriers facing this population.
Researchers have made significant advancements in nuclear medicine by developing a new reporting framework for PET/CT scans, using targeted radiation therapy to treat sarcoma, and investigating how genetic mutations affect prostate cancer treatment outcomes. These studies aim to improve diagnosis and treatment for various cancers.
Researchers at the Center for Cell-Based Therapy developed a new approach to enhance CAR-NK cell cytotoxicity, combining optimized co-stimulation with reversible pharmacological control. The study showed increased tumor control in animal models, paving the way for improved cancer treatment.
Researchers found a significant association between tropical cyclone exposure and psychoactive drug-related deaths, with the effect more pronounced in wealthy, White communities. Younger populations, especially those aged 15 to 29 years, were also disproportionately affected.
A cohort study found that adolescent cannabis use is associated with an increased risk of developing psychiatric disorders, particularly psychotic and bipolar conditions. The study's results inform the development of interventions and policies to prevent or delay adolescent cannabis use.
A UT Health San Antonio researcher will study how microglia contribute to the spread of toxic tau protein in Alzheimer's disease. The study aims to clarify whether microglia act as barriers or accelerators in the cascade of the disease, potentially leading to new treatments.
Researchers at Goethe University used X-ray radiation to determine the spatial structure of formic acid, finding that its atoms oscillate slightly back and forth. This 'quantum trembling' causes the molecule to lose its symmetry and become effectively three-dimensional at almost every moment.
Researchers have identified a field of tektites in Brazilian territory, which may have been formed by a single cosmic collision event. The geraisites, named after the Brazilian state of Minas Gerais where they were first discovered, have distinct geochemical signatures and date back approximately 6.3 million years.
This cross-sectional study highlights critical gaps in accessible mental health services for adults with intellectual and developmental disabilities. The findings underscore the need for policy reforms to address systemic inequities and provide disability-informed care.
The Massage Therapy Foundation has awarded a $300,000 research grant to the University of Denver to investigate the benefits of incorporating prenatal massage into the MotherWise program. The study aims to assess potential benefits, including reduced rates of postpartum depression and improved anxiety, pain, and sleep scores.
Researchers at NTNU believe they've discovered a potential superconductor, NbRe, that can enable spin-based computing with near-zero resistance. This breakthrough has significant implications for the future of quantum technology and could lead to faster, more energy-efficient computers.
The study provides detailed information on NrdR, a master regulator of ribonucleotide reductases in bacteria. It reveals how NrdR senses nucleotide levels and controls RNR expression, providing a new strategic entry point for antimicrobial development.
A new study examines the mechanisms, clinicopathological features, and management strategies of GI toxicity induced by targeted cancer therapies. The authors highlight the importance of close collaboration between oncologists, gastroenterologists, and pathologists to ensure accurate diagnosis.
Researchers identify delirium as a common but underestimated complication in cardiac medicine, associated with longer stays, increased mortality, and cognitive decline. Prevention strategies, including non-pharmacological measures, can reduce the incidence of delirium by up to 40%.
Researchers conducted the SANAT flight campaign to study aerosols' role in cloud formation in Antarctica. They collected extensive data on aerosol frequency, transport processes, and chemical composition, revealing an unexpectedly high aerosol concentration in the interior.
The Bial Award in Biomedicine 2025 will announce its winner on February 24, 2026, with a €350,000 prize. The award recognizes outstanding biomedical discoveries published within the last 10 years.
A new international study presents a comprehensive framework for understanding and managing cross-scale socioeconomic and environmental interconnections. The metacoupling framework helps connect the dots across systems, scales, and borders to accelerate progress toward Sustainable Development Goals (SDGs) by 2030.
Epic Games has acquired Meshcapade, a Max Planck startup that develops solutions for creating and animating digital humans. The technology, based on the SMPL body model, enables realistic human movement and expression in 3D.
Researchers at the University of Gothenburg have found that tirzepatide, the active ingredient in Mounjaro, reduces voluntary alcohol consumption by more than half in animals. The study also shows that the drug prevents relapse-like drinking and decreases drinking levels after a period without alcohol.
A team of CDI scientists has identified the genetic basis of Acinetobacter baumannii's resistance to Cefiderocol, a last-line antibiotic. The study provides insights into the evolution of resistance and highlights the need for integrated surveillance strategies to prevent further resistance.
Researchers found NfL levels increase with age in various animals, including mammals, birds, and reptiles. The protein can help assess biological age and predict life expectancy across species.
The study reveals that psychosis does not follow a single trajectory but is influenced by individual differences and treatment. It shows that cortical volume reduction, particularly in regions with high serotonin and dopamine receptor density, is a hallmark of the disease.
Researchers from Insilico Medicine and Lilly outline a comprehensive framework for fully autonomous, AI-orchestrated drug discovery. The vision integrates AI-driven target discovery, generative chemistry, automated synthesis, biological validation, and clinical planning into a single workflow.
Researchers tracked 17 bird species crossing Sahara Desert and Mediterranean Sea using miniature tracking devices. Birds flew at varying altitudes depending on wing morphology and plumage color, with some species flying extremely close to the water surface.
A recent study found that 81% of hikers rely on mobile phones for navigation, increasing the risk of getting lost or ending up in dangerous situations. Researchers emphasize the need for alternative strategies, such as using paper maps, marked trails, and asking other hikers, to ensure safe travel.
A novel wireless origami-inspired smart cushioning device has been developed to monitor deformation and detect damage to transported goods. The self-folded origami honeycomb device, integrated with passive wireless sensors, can provide real-time information on load conditions and impact.
Despite increased procedures, mortality rates remain high due to varying levels of care across Europe. Higher GDP per capita is associated with lower MI mortality rates, while greater CVD prevalence increases rates.
Researchers developed a winged composite pile foundation system to enhance wind resistance and utilize surplus excavated soil. The study found that larger expanded base wing diameters significantly increased uplift resistance, while soil density and surface characteristics of the steel components also played crucial roles.
Researchers developed a new model to predict long-term survival after heart failure in elderly Japanese patients. The Top-20 XGBoost model incorporates physical function metrics, rivaling the importance of traditional cardiovascular risk factors, and provides a more accurate estimation of mortality risk.
A large registry study identifies a specific genetic mismatch linked to severe acute graft-versus-host disease (aGVHD) after cord blood transplantation, tripling the risk of life-threatening complications. Researchers found that a particular HLA combination in donors and recipients increased aGVHD risk by threefold.
Researchers found that both screening methods lead to more cases of early-stage cancer being detected, especially in the first two years. The study suggests that screening may have a preventive effect by removing precursors to cancer.
Researchers have uncovered a previously unknown genomic structure that emerges in developing germ cells, crucial for successful meiosis. This discovery may help create functional sperm and eggs outside the body, paving the way for new treatments for infertility.
Researchers have deciphered the signalling chain that stimulates plant root growth in response to nitrate. A key gene called MEKK14 determines the strength of this process, with more active variants leading to improved growth.
A new analysis of the Serbian SCAD Registry found that SCAD is most common in non-pregnant young women and menopausal women, often resolving fully without stent implantation. Careful observation alongside beta-blockers and psychological support may improve outcomes, but further studies are needed.
The new open-access reference guide emphasizes that breeding objectives must reflect farmer priorities and production realities. Local breeds are critical for climate adaptation and resilience in small-scale and low-input production systems, but many are at risk of extinction due to indiscriminate crossbreeding with exotic breeds.
A new study reveals the best- and worst-case scenarios for climate change in Antarctica, highlighting the urgent need to reduce emissions. Under high-emissions scenarios, Antarctica's ice shelves, glaciers, and iconic species could collapse, driving sea level rise and devastating ecosystems.
Researchers observed cleaner wrasse recognizing themselves in mirrors and experimenting with it, suggesting advanced intelligence known as 'contingency testing'. The fish also demonstrated flexible, self-referential processing, indicating widespread self-awareness across taxonomic groups, including fish.
Researchers at KIST developed an all-in-one single-atom water electrolysis catalyst that stably performs both hydrogen evolution and oxygen evolution reactions on a single electrode. This technology significantly reduces precious metal usage while achieving outstanding performance and durability.
A new multicenter study by Kumamoto University and National Cerebral and Cardiovascular Center found that working-age adults with shorter sleep durations are more likely to develop atrial fibrillation. In contrast, retirees showed no significant association between sleep duration and AF risk.
A new study from Timor-Leste shows that increasing fish supply alone is not enough to tackle malnutrition; targeted nutrition messaging and public awareness are also necessary. The study found that households exposed to both increased fish availability and nutrition campaign were nearly twice as likely to purchase fish.
Developed at Tohoku University's Advanced Institute for Materials Research, the new catalyst enables smoother hydrogen formation under alkaline conditions. The auxiliary-driving strategy improves both steps of the hydrogen evolution reaction, resulting in higher hydrogen evolution activity and efficient production with low energy loss.
A University of California - Riverside study has identified bed bugs' fear of water and wet surfaces, which affects their behavior and movement patterns. Researchers found that all bed bug ages and genders avoid wet surfaces, with younger insects being more sensitive to moisture.
A new study by the University of Cambridge found that many AI bots lack basic safety disclosures, including transparency about their abilities and potential risks. The 'AI Agent Index' revealed a significant transparency gap, with only four out of thirty agents publishing formal safety and evaluation documents.
Researchers found that Discord community Medimura functions as a 'third place,' providing a safe space for players to connect and share daily life. The study highlights the importance of digital platforms in promoting social wellbeing, particularly in Japan where casual social interactions can be limited.
A green and efficient photo-redox/hydrogen atom transfer synergistic catalytic strategy successfully synthesizes chiral α-aryl cyclic ketones. Thiophenols activate carbonyl compounds through Brønsted acid and HAT catalyst roles.
Researchers have developed a new way to generate acoustic frequency combs using phonon lasers, producing tunable comb teeth spanning from audible to ultrasonic frequencies. The breakthrough enables the creation of ultrabroadband acoustic frequency combs with thousands of evenly spaced frequencies.
A study published in the Journal of Apicultural Research found that combining a widely used mite-killing pesticide with an agent inhibiting its tolerance can effectively control varroa mites. The new treatment increases amitraz's killing power by 50% and shows promise for developing novel synergists to target these destructive mites.
A new study from the University of East Anglia found that babies with an increased likelihood of autism may struggle to settle into deep, restorative sleep. Those with high sensory sensitivity slept more lightly even in quiet environments.
The CU Anschutz School of Medicine has achieved the best ranking in NIH funding in 20 years, moving to No. 21 among all medical schools. This is attributed to the growth in NIH funding from $314 million, with nine clinical departments ranked in the top 15.
The Mayo Clinic Representative Office in the Cayman Islands will help patients make appointments at Mayo Clinic locations worldwide. The staff also assist with travel arrangements, billing, and insurance coordination, providing free services to patients and their families.
Researchers used high-resolution simulations to identify the impact of stellar rotation on element transport across a barrier layer in red giant stars. They found that rapid rotation amplifies wave mixing, resulting in observed chemical signatures.
The International Progressive MS Alliance has funded three global studies to address common symptoms of progressive MS, such as fatigue and cognitive impairment. These Well-Being Phase II Efficacy Awards aim to develop innovative approaches for improving well-being in people with progressive MS.
Researchers develop a new method to transform waste streams into a promising material for next-generation sodium-ion batteries. The study demonstrates how waste recycling can reduce environmental pollution and support the transition to sustainable energy storage technologies.