Researchers identified three master regulator genes on chromosome 21 that disrupt normal brain activity in individuals with Down syndrome. Overactivating these genes was linked to disruptions in hundreds of other genes involved in learning and memory, providing new insights into the condition.
Daily aspirin use offers no quick or reliable way to prevent bowel cancer in the general population, increasing risk of serious bleeding. However, it may have potential long-term benefits for people at high genetic risk of colorectal cancer.
Researchers at Kobe University found that liverwort's hair-like rhizoids take in and transport phosphorus to its tissues, contrary to initial assumptions. This discovery sheds light on the evolution of nutrient acquisition mechanisms in simple land plants like mosses and liverworts.
Research at Flinders University found that a thinking style known as systemising, which seeks patterns and consistency, can lead individuals to believe in conspiracy theories despite good scientific reasoning skills. This cognitive style can make it difficult for people to update their beliefs when faced with new evidence.
The Baskerville National Compute Resource (NCR) will benefit researchers in various disciplines with advanced data processing capabilities. The facility harnesses accelerator technology to process vast amounts of data at incredible speed, helping researchers achieve breakthroughs faster than ever before.
A new study by Harvard T.H. Chan School of Public Health and the Department of Veterans Affairs Boston Healthcare System found that using GLP-1 receptor agonists in combination with adhering to healthy lifestyle habits significantly reduces cardiovascular risk among individuals with type 2 diabetes. The study showed that these two stra...
As climates become more extreme, traditional building designs are failing to keep people safe and comfortable. A new generation of architects is creating climate-ready buildings that can maintain comfortable temperatures independently from the grid, using local natural resources like sun, wind, and ground-sourced energy.
Researchers from the University of Oxford have resolved a long-standing debate about the Moon's magnetic field, finding that it had an extremely strong field at times but was mostly weak. The new analysis suggests that the Apollo samples were biased to record rare events, leading scientists to overestimate the field's strength.
Only 6 of every 10 finalised post-authorisation studies uploaded protocols and less than 7% had results available for EMA's database. This lack of transparency hinders scientific review and research credibility.
Researchers found that children who aren't friends connect better through play when given a task to complete, especially during goal-directed activities. The study, which involved 148 children aged six to eight, shows that connected communication is crucial for social coordination and teamwork.
A new study published in Global Ecology and Conservation found that released animals, like Bengal slow lorises, are at risk of being attacked by territorial peers. Only two out of nine released animals survived, with the others dying due to fatal attacks.
A nationwide study in Sweden found that HPV vaccination significantly reduces the risk of invasive cervical cancer, with sustained protection observed for 13-15 years after vaccination. The study also showed a population-level decline in cervical cancer cases over time.
A new study published in Cardiovascular Research found that a single night of road traffic noise can cause stress to the heart and blood vessels, impairing blood vessel function and raising heart rate. The study also showed changes in inflammation and stress responses linked to nighttime noise exposure.
Scientists have discovered how engineered biochar and microbes work together to enhance phytoremediation by improving soil conditions and stimulating beneficial microbes. The study found that modified biochar substantially increased plant growth, boosted photosynthesis, and promoted the transfer of cadmium from roots to stems and leaves.
A randomised control trial conducted on 587 gay and bisexual men found no effect of the meningococcal B vaccine (4CMenB) on preventing gonorrhoea. The study's results suggest that alternative prevention methods, such as condoms and regular testing, are necessary to combat the rise in antibiotic-resistant gonorrhoea strains.
Mayo Clinic has been ranked as the No. 1 hospital in the world for its eighth consecutive year by Newsweek, based on patient survey results and key performance metrics. The organization is transforming healthcare through its Bold. Forward. strategy, which combines deep clinical expertise with responsible digital innovation.
A new review highlights how engineering biochar with magnetic and mineral modifications can expand its environmental applications while overcoming practical limitations. Engineered biochars combine adsorption with reactive processes to trap pollutants, transform or degrade them, reducing the risk of secondary contamination.
The AAO-HNSF is developing evidence-based tools to address hearing loss, vestibular dysfunction, and fall risk in older adults. The project aims to equip otolaryngologists with specialty-specific tools to improve care quality and empower patients to have more meaningful conversations.
A team of environmental chemists developed a new catalyst made from discarded coffee grounds that efficiently removes hydrogen sulfide, a highly toxic industrial gas, while producing elemental sulfur. The material was produced through a two-step process and demonstrated outstanding performance during laboratory testing.
A global team of scientists, led by University of Houston microbiologist Madhan Tirumalai, has identified the critical role of biofilms in human space exploration. Biofilms could influence astronaut health, drug delivery and space agriculture, while also posing risks to astronaut health.
The study found that telemedicine patient visits were billed $400 less and resulted in fewer follow-up visits compared to in-person appointments. For respiratory symptoms, telemedicine appointments were cheaper by roughly $800 on average, highlighting its cost-efficiency.
A new study reveals that brain rhythms shift attention multiple times per second, affecting focus and increasing susceptibility to distractions. This rhythmic occurrence may help us avoid overfocus on one thing, but also make us more prone to digital alerts and visual stimuli.
A study found that COVID-19 infection significantly increases the risk of acute kidney injury, chronic kidney disease, and kidney failure in US adults. The research used machine learning models to analyze data from over three million patients, revealing a 2.3-times higher risk of acute kidney injury compared to influenza.
A new study published in Neurology found that currently smoking is associated with a lower risk of developing Parkinson’s disease, but quitting smoking was associated with a lower risk of death. Researchers also found that sustained quitters had a 17% lower risk of death compared to persistent smokers.
Researchers found that some membrane-less compartments are built from tiny filaments, revealing new possibilities for therapeutic intervention in diseases such as cancer and neurodegeneration. The discovery suggests that targeting these structures could be effective in treating conditions like ALS and tumors.
The semiconductor industry is shifting from compute to memory as ultra-large AI models demand higher performing chips. SK hynix is increasing bandwidth by a factor of 1.5x every two years, while GlobalFoundries uses AI to improve process control and manage diverse manufacturing processes.
Researchers demonstrated a breakthrough in microrobotics: swarms of magnetic microrobots can manipulate objects without physical contact by harnessing fluid-generated torque. The microrobots act as motors to move millimeter-sized passive objects, opening new pathways for precision manufacturing and biomedical applications.
Researchers found that trees with heart rot disease release more methane than healthy trees, regardless of disease severity. Methane emissions peak in the trunk's center, a finding that challenges previous assumptions about tree health and greenhouse gas cycling.
A study published by the American Academy of Neurology found that being an early bird and engaging in more physical activity are linked to a reduced risk of amyotrophic lateral sclerosis (ALS). After adjusting for various factors, researchers discovered that individuals who followed a sleep schedule that matched daylight hours and had ...
Researchers at UNLV have created a 3D-printed synthetic California sea lion pelvic region, enabling medical professionals to conduct blood collection training on anatomically authentic models. This innovation has the potential to improve veterinary procedures and benefit human lives in the long run.
Researchers identify nonsense-mediated mRNA decay (NMD) as a central mediator of neuronal migration and cortical lamination. The study reveals that UPF2, a core component of NMD machinery, is essential for proper neuron migration and brain development.
Medical care improvements in the U.S. have increased health spans by 1.3 years and reduced lifetime healthcare spending by $234,000 per person over their lifetime. For many diseases, investing early in prevention and treatment can lead to cost-effective gains later on.
Researchers found that less transparency in bond markets can lead to better economic outcomes, as it imposes discipline on players and makes institutions more selective about bonds they buy. This is in contrast to the 2008 global financial crisis, which was triggered by too much public information and looser credit.
Researchers have developed a new method for qualifying materials for use in advanced nuclear reactors, which uses ion beams to mimic radiation damage. This approach can be done at a fraction of the cost and time required by traditional test reactors.
A ketogenic diet causes physical changes in brain cells that affect how they send information to one another, dampening the strength of signals between them. This quieter neural landscape might explain how the diet calms overactive electrical signaling characteristic of epileptic seizures.
The Rubin Observatory has launched a real-time monitoring system, producing up to 7 million alerts per night, which will enable scientists to discover rare and unusual objects in the universe. The alerts will chronicle the treasure trove of scientific discoveries made through the observatory's time-lapse record of the universe.
A new study reveals that exposure to extreme heat during pregnancy significantly alters the human sex ratio at birth, leading to fewer male births. In sub-Saharan Africa, this is driven by biological factors, while in India, it is influenced by cultural practices and behavioral changes.
A recent study published in Science Translational Medicine found that infant immune systems respond very differently to RSV and SARS-CoV-2, with important treatment implications. Infants infected with RSV often develop severe symptoms due to low levels of systemic inflammation and a poorly coordinated early immune response.
Researchers at Michigan State University found that AI agents that mimic human behavior can lower the threshold to cooperation, producing larger pools of reciprocity. This study suggests that AI could be used to promote cooperation in self-driving vehicles and other real-world scenarios.
Researchers discovered higher levels of inflammation in football players were associated with worsened brain structure and related cognitive decline. The study, published in Neurology, also found associations between repeated head impacts and neurobehavioral dysregulation.
Researchers at WashU Medicine have found that disrupted lymphatic vessels may trigger chronic organ rejection in transplanted lungs and hearts. The study suggests that preventing hyaluronan buildup or restoring lymphatic drainage could prevent fibrosis and long-term damage.
Researchers from UC Irvine have discovered a critical security vulnerability in autonomous target-tracking drones that can be exploited using an ordinary umbrella. The team demonstrated how attackers could use the 'FlyTrap' attack framework to manipulate drones, drawing them close enough for capture or causing them to crash.
A new analysis across 45 years suggests that the disparity in firearm homicide deaths between Black and White Americans has grown, with many thousands of Black lives lost. The study found that Black males faced an eight to nine times higher likelihood of firearm homicide death than White males from 1988 to 2010.
Researchers have discovered a way to enhance awake brain mapping, allowing neurosurgeons to remove more cancerous tissue while minimizing disruptions to patients' quality of life. The new technique uses subtle changes in patient behavior to inform surgical decisions.
A new, daily oral tablet that combines two current HIV treatment medications has shown highly effective control of the HIV virus in a phase 3 clinical trial. Nearly 96% of participants maintained viral control with no new drug resistance reported.
A new daily oral tablet combining bictegravir and lenacapavir (BIC/LEN) was found to be highly effective in maintaining HIV suppression, with nearly 96% of participants who switched to this simplified regimen maintaining viral suppression. The treatment showed similar results compared to complex, multi-pill treatments.
Research finds that humpback whales face a higher risk of getting entangled in fishing equipment during years with lower availability of cool-water habitat. The Habitat Compression Index can predict ocean conditions up to a year in advance, suggesting its potential as an early warning system for fishery management decisions.
A study predicts that climate change will shift suitable habitat for monarch butterflies southwards, disrupting their mass migration. The results show a decline in suitable habitat of between 8% and 40% by 2070, fracturing existing migrating routes.
A study of over 8,000 tropical flowers found that their blooming periods have shifted by an average of two days per decade, with some species flowering up to 17 days earlier or later than they used to. This change could have significant ecological impacts on pollinators and herbivores.
A survey of 1,998 US adolescents aged 10-19 found nearly 1 in 3 have diabetes or prediabetes. Waist-to-height ratio emerged as the strongest independent predictor of these conditions.
A study published in PLOS One found that fetuses who yawned more frequently during pregnancy had a lower birth weight, suggesting mild fetal distress. The research observed healthy fetuses between 23-31 weeks and recorded their yawning behavior using ultrasound.
A new study published in Science Advances has shed light on how the body responds to energy demands from exercise, identifying a crucial cell signaling mechanism that could lead to a new treatment for diabetes. The research focuses on Adenosine Monophosphate-Activated Protein Kinase (AMPK), a regulator of energy production, and reveals...
An online experiment with 1,051 US adults suggests flagging potentially false cancer treatment claims on social media can help reduce the spread of misinformation. The study found that intervening and reducing sharing of false information on social media may have a positive impact on public health.
A new study from Ethiopia reveals that conservation agriculture methods like no-dig, crop-rotation, and mulching can significantly reduce water runoff and soil loss. These eco-friendly techniques have been shown to increase crop yields by as much as 122%.
Researchers have developed a new chemistry-based strategy to localize therapeutic drugs to tumors, reducing harm to healthy tissues. The 'lock-and-key' system uses biorthogonal supramolecular chemistry to release drugs in specific locations, offering a potential path to safer and more precise cancer treatment.
The report highlights the need for an agreed definition of healthy soil, scalable biological indicators, and collaborative transitions to sustainable land management practices. It emphasizes the importance of building trust and aligning diverse priorities among all soil stakeholders.
Scientists investigate how recycled sewage interacts with simulated lunar and Martian regolith to create a suitable medium for crop growth. The experiment reveals that the weathered simulants supply essential plant nutrients, paving the way for sustainable human colonies in outer space.
Researchers discovered that high-dose vitamin B3 can dramatically extend survival in mice with NAXD deficiency, a devastating genetic disease. The study identifies dozens of other genetic conditions potentially responsive to vitamin therapy.
Benzodiazepine use decreased across the US from 2018 to 2022, with the greatest decline among older adults. Nearly half of patients receiving benzodiazepines also took other central nervous system depressants, increasing the risk of adverse effects.
Researchers developed a method to produce durable lactate-based polyester with improved mechanical properties, comparable to traditional polymers. The new process resulted in a high molecular weight and balance of strength and elongation.