A £4.7m Policy Research Unit will focus on improving cancer screening and diagnosis in the UK. The team from Peninsula College of Medicine and Dentistry aims to identify key symptoms that should prompt GPs to take action, with the goal of boosting survival rates and reducing mortality.
New research shows vitamin D can speed up antibiotic treatment of tuberculosis (TB), clearing bacteria from the lungs in just 5 weeks for certain patients. Vitamin D deficiency is a common problem among TB patients, and those with a specific genetic type of vitamin D receptor responded better to supplementation.
The Louis Stokes Alliances for Minority Participation (LSAMP) program at IUPUI is successfully encouraging minority students to select STEM majors and pursue careers. Students like Kathryn DelaCruz and Tomás Meijome are thriving in research projects, internships, and graduate programs.
During pregnancy, pregnant women can experience significant changes in their oral health, including gingivitis, pregnancy tumors, and mild to severe gingival enlargement. Regular dental check-ups and proper oral hygiene can help alleviate gum inflammation and prevent worsening of conditions.
The American Association for Dental Research (AADR) presented a record-breaking turnout of 22 scientific posters on cutting-edge salivary diagnostics research. Key findings included emerging technologies and translational applications in the field, marking a significant milestone for the organization.
Researchers at the University of Alberta have developed a new method to analyze biopsies from heart transplant patients by examining their genes, allowing for early prediction of treatment success. This approach uses software algorithms to reduce data to key numbers necessary for diagnosis and prognosis.
Researchers identify FOXM1 as a key player in initiating human cancer by exploiting the self-renewal property of stem cells, leading to excessive cell growth and pre-cancerous conditions. The study aims to translate these findings into molecular diagnostic tests and anti-tumour drugs.
A project led by Mr Hemant Kocher aims to target the stroma surrounding pancreatic cancer tumours, which is believed to drive tumour growth and prevent drug treatments from reaching the tumour. The research may lead to new drug targets for treating pancreatic cancer, a disease with poor survival rates.
A study by the University of Michigan found that teriparatide, a drug marketed for osteoporosis, can also heal bone wounds in gum disease patients. The treatment showed a 29% improvement in bone-level measurements on x-rays, compared to a 3% improvement in the placebo group.
Researchers are studying a rare form of Hepatitis E affecting middle-aged and elderly men in the UK. The two-year study will examine liver problems in hospital patients and explore transmission through contact with pigs and products.
Researchers found that majority of heart failure patients pass away in acute care hospital, resulting in significantly higher costs. The study examined data from over 30,000 elderly patients with heart failure who died between 2000 and 2006 in Alberta, highlighting the need for discussions about end-of-life care options.
A University of Alberta research team has found a mechanism underlying both addiction and obesity, which could lead to new treatments for these diseases. The study revealed that dopamine plays a key role in the formation of spatial memories in the brain, and its release is associated with feelings of reward.
A Purdue University-led research team has uncovered the chemical components of oyster adhesive, which could aid in boosting dwindling oyster populations and creating non-toxic materials to prevent marine fouling. The findings also have implications for dentistry and construction.
According to a study published in JADA, asthma and cavities are both prevalent childhood diseases in the US. However, researchers found little evidence suggesting that asthma causes tooth decay, with some studies showing children with asthma having fewer cavities.
Researchers at Mount Sinai School of Medicine found that BPA released from plastic resins used in pediatric dentistry is detectable in saliva after placement in children's mouths. The team recommends using alternative BPA derivatives and taking precautions to reduce exposure.
Researchers at the University of Alberta have discovered a crucial mechanism for fighting infections, revealing that an amino acid called arginine is essential for immune function. The study's findings could have significant implications for people in third world countries with limited access to nutrition.
NYU researchers found that periodontal inflammation increases cognitive dysfunction risk in healthy individuals and those with Alzheimer's. The study linked gum inflammation to brain inflammation, neurodegeneration, and Alzheimer's disease.
A pilot-dentist duo proposes adapting airline crew resource management principles to dental offices, aiming to reduce human errors and improve patient safety. By implementing standardized safety procedures and empowering team members with CRM checklists, dentists can significantly reduce complications and deaths in surgical settings.
Scientists have developed a multilayered, nano-sized film containing alpha melanocyte stimulating hormone to regenerate dental pulp, potentially revitalizing damaged teeth and reducing the need for root canal procedures. The film has anti-inflammatory properties and increased the number of fibroblasts in dental pulp.
Researchers at OHSU School of Dentistry use ATP-driven bioluminescence to assess children's oral bacteria and plaque, linking it to caries risk. The study finds a strong statistical association between ATP measurements and bacterial numbers in saliva and plaque specimens.
Children with special health care needs are at higher risk of developing oral disease. Poor diets, frequent use of sugary syrups, and inadequate oral hygiene can exacerbate the issue.
The Journal of Dental Research (JDR) has maintained its number one ranking in the 'Dentistry, Oral Surgery & Medicine' category, according to the new 2009 Five-Year Scientific Impact Factor (SIF) rankings. The JDR's SIF increased from 3.966 to 4.195, demonstrating its continued importance and relevance in the field.
Providing oral health education to mothers and families is essential for teaching children healthy habits and preventing early childhood tooth decay. A general dentist can provide families with oral health literature designed to educate both the parent and child, promoting a positive self-image and improving their quality of life.
Good oral health during pregnancy combats adverse effects of oral disease, preventing pain, infections, and nutrient deficiencies. Regular dental treatment can be safely performed at any time during pregnancy.
Researchers have developed a new model to investigate the link between tobacco use and oral cancer, using carcinogens found in tobacco smoke. The study shows that this approach can lead to better understanding of oral cancer initiation, progression, and prevention.
A study by the Academy of General Dentistry found that triclosan/copolymer toothpaste is more effective at killing harmful germs in the mouth than regular fluoride toothpastes. This can help minimize cavities, gum disease, and bad breath.
A recent study published in the Academy of General Dentistry's peer-reviewed journal found that drinking fluoridated tap water can significantly reduce cavities and promote remineralization. The controlled addition of fluoride to public water supplies is considered a cost-effective way to prevent tooth decay.
Chronic mouth breathing can lead to abnormal facial and dental development, poor sleeping habits and academic performance. Treatment options are available, including surgical removal of tonsils and adenoids, and orthodontic intervention.
Researchers will measure BPA levels in over 1,000 people with heart disease undergoing bypass surgery and thousands of individuals from Norfolk studied for over 10 years. The study aims to clarify whether BPA is linked to heart disease, which could impact public health by leading to controls on its use.
Researchers at OHSU School of Dentistry have discovered that inflammation boosts the production of a protein involved in pain signaling, which could lead to new treatments for craniofacial pain conditions. The findings provide a crucial understanding of the molecular mechanisms underlying trigeminal pain.
A research team at Oregon Health & Science University has discovered that nitric oxide is a powerful regulator of brain-derived neurotrophic factor (BDNF), a molecule involved in the development and function of the nervous system. This finding could play a significant role in preventing and treating high blood pressure.
The American Association for Dental Research (AADR) has awarded David C. Johnsen, dean of the University of Iowa College of Dentistry, with the 2010 Jack Hein Public Service Award. Johnsen is recognized for his tireless advocacy for oral health research funding and training.
Irwin D. Mandel, a renowned researcher and mentor, received the inaugural AADR Distinguished Mentoring Award in 2010. The award recognizes his long-term dedication to fostering and promoting research training and career development among students, trainees, and junior faculty.
Dolphus Dawson, III, receives the 2010 AADR Neal W. Chilton Fellowship for biostatistical analysis of a dataset from the Effects of Periodontal Therapy on Preterm Birth (OPT) study. The analysis will investigate associations between clinical measures and preeclampsia in the OPT study population.
The University of Plymouth is investing £500,000 in joint research with the Peninsula Dental School to tackle key areas in oral health. The research will focus on statistical epidemiology, virtual reality, and nanotechnology, aiming to ease dental anxiety and develop more aesthetically pleasing materials.
Research finds that African-American patients with type 1 diabetes who consume more calories and sodium are more likely to develop vision-threatening retinopathy. Low caloric and sodium intakes may have a beneficial effect on the progression of diabetic retinopathy in this population.
A study led by Dr. Shiela Strauss found that 93% of individuals with periodontal disease are at high risk for diabetes, compared to 63% without the disease. This suggests that dental offices could serve as a valuable platform for initial diabetes screening.
Researchers at USC School of Dentistry have successfully reversed a cleft palate in fetal mice by regulating signaling molecules. The study's findings suggest that close monitoring and regulation of the protein Shh during palate formation may one day allow for non-surgical reversal before birth.
The Canadian Cardiovascular Society recognizes Dr. Gavin Y. Oudit's groundbreaking research on a new class of drugs for treating heart failure, with the potential to also treat kidney and lung diseases. Oudit's innovative program has yielded major discoveries and established him as a world leader in this exciting area of research.
A study published in the Journal of Dental Research found that dental plaque accumulation led to increased neutrophil activity in black males, but not in other groups. This response may indicate a higher risk for infections and heart disease in these individuals.
The UCLA School of Dentistry is building a state-of-the-art cancer research facility to consolidate and expand its oral cancer research. The Yip Center for Oral/Head & Neck Oncology Research will include cutting-edge laboratories for genomics, proteomics, and salivary diagnostics research.
Researchers at UCLA have confirmed the effectiveness of measuring microRNAs in saliva to detect oral squamous cell carcinoma. The study identifies two specific microRNAs, miR-125a and miR-200a, that are present at significantly different levels in the saliva of individuals with oral cancer.
Researchers developed a non-toxic method to synthesize zinc oxide nanorods using water and ultrasound. The approach produces uniform nanorods of 30-100 nm in diameter, suitable for large-scale production. It enables safe use in medical applications, food products, dentistry, and electronics.
Dr. Michael E. O'Brien has been recognized for his outstanding contributions to dental education, receiving the Daniel M. Laskin Award for Outstanding Predoctoral Educator in Oral and Maxillofacial Surgery. He is a respected educator, mentor, and clinician with over 25 years of experience at LSUHSC.
Janet Leigh, Chair of Oral Medicine and Radiology at LSUHSC New Orleans School of Dentistry, is a RWJF Health Policy Fellow. She will participate in the policy process at the federal level, accelerating her career as a leader in health policy.
The Peninsula College of Medicine and Dentistry has received a grant to study the role of brain tumors in deafness and develop non-invasive therapies. The research aims to identify how tumors grow and cause hearing damage, and test drug-based treatments.
Daily consumption of acidic beverages can lead to demineralization of hard dental tissues, causing tooth structure to wear away. To manage erosion, identify the culprit source, understand its effects on teeth, and stop or reduce consumption. Regular dental check-ups twice a year can help maintain healthy teeth.
Recent research published in the Academy of General Dentistry's clinical journal revealed that aloe vera tooth gel is as effective as commercial toothpaste in controlling cavity-causing organisms. The study found that aloe vera tooth gel was more effective than some commercially popular brands, making it a great alternative for people ...
Dry mouth, caused by decreased salivary function, affects one in four Americans and is linked to over 400 prescription and non-prescription drugs. Patients may experience symptoms like constant thirst, difficulty eating or speaking, and increased tooth decay risk.
Periodontal disease has been linked to an increased risk of cardiovascular disease, with as many as 75% of adults in the US affected by periodontal disease. The study suggests that addressing oral/body inflammatory connection can improve overall health and reduce CVD risks.
Dental CAD/CAM technology enables dentists to create porcelain restorations efficiently, eliminating multiple visits. This technology minimizes stress and strain on patients, saving them precious time and money.
Researchers develop nanotechnology process to prevent bonding failure in composite resin fillings. By feeding minerals back into the collagen network, they aim to create a delivery system that can repair cavities on their own.
Researchers at USC School of Dentistry and Viterbi School of Engineering developed a non-thermal plasma dental probe that destroys bacterial colonies and disinfects hard-to-reach areas. The tool uses pulsed power to create a room temperature plasma with antibacterial properties.
Alpesh Patel, a senior at MCG School of Dentistry, has identified proteins responsible for inhibiting oral cancer cell growth when exposed to blue curing light. He found that this phenomenon reduces tumor growth in mice, offering a promising alternative treatment.
Dr. Xu's research aims to develop novel dental materials that release fluoride, inhibit bacterial growth, and promote bioactivity, potentially reducing secondary cavities and improving oral health outcomes. The project has the potential to impact high-risk populations, such as children, the elderly, and those with compromised oral health.
Researchers have identified a protein responsible for regulating branched-chain amino acid catabolism, which may be linked to Maple Syrup Urine Disease. Additionally, immune cells called V-alpha-24-invariant NKT cells can indirectly affect neuroblastoma growth by killing tumor-associated cells that promote its growth.
Researchers identified CEACAM6 as a key factor blocking the effectiveness of adenovirus-based therapies in treating cancer. Knocking down CEACAM6 expression increased anticancer effects in mice with human tumor cells.
A new study by OHSU School of Dentistry found that patients with self-ligating orthodontic brackets retained significantly fewer oral bacteria in plaque compared to those with elastomeric brackets. The researchers also developed a rapid and reliable method for quantifying oral bacteria using ATP-driven bioluminescence.
A new study from Ohio State University found that home tooth bleaching products reduce enamel hardness by 1.2-2 nanometers, affecting its ability to bounce back after force. Researchers suggest reformulating products to minimize side effects.
Researchers found that drinking white wine can lead to darker tooth stains due to acids creating rough spots and grooves. Red wine still causes more severe staining than white wine, but a whitening toothpaste can help prevent both types of stains.