A WVU engineer has developed a technology that can treat urine on site rather than at a centralized wastewater treatment facility, allowing for the recovery of nitrogen as a valuable fertilizer. The approach enables quick treatment and promotes the reduction of nutrient discharge into lakes and rivers.
A team of scientists, led by Marco Fraaije from the University of Groningen, has developed an enzyme that can convert lignin monomers into useful chemical building blocks. The enzyme has been engineered to be stable, selective, and faster in conversion, offering a promising solution for the valorization of biomass.
The scientists emphasize the need for urgent course correction due to inconsistent chemical frameworks. They highlight the importance of comprehensive chemical regulation from production stages to product use and disposal.
Researchers develop CRISPR-Cas systems associated with transposons to rewrite large chunks of DNA in organisms like E. coli. This expands the CRISPR toolbox for flexible genome editing and has significant implications for therapeutics, biotechnology, and agriculture.
Researchers in Singapore, Saudi Arabia, and Finland achieved first insights into engineering crystal growth by atomically precise metal nanoclusters. They synthesized gold clusters consisting of 25 atoms, regulating their size and concentration to form well-defined crystals with unique morphology.
Researchers at Argonne National Laboratory have identified promising new biofuels that can reduce greenhouse gas emissions by up to 60% while improving fuel efficiency or reducing tailpipe emissions. The biofuels, developed using advanced engine design, can be blended with conventional fuels to improve engine performance and meet more ...
Researchers develop two-stage approach converting mixed plastic waste into polyhydroxyalkanoates, a family of bioplastics suitable for medical materials. The hybrid process combines metal ion-promoted oxidation and bioconversion via genetically modified soil bacterium, enabling efficient recycling of commonly used plastics.
The Rutgers team developed an analytical toolkit to measure protein-carbohydrate interactions with single-molecule precision. By adjusting the 'stickiness' of enzymes, they aim to enhance cellulose decomposition for biofuels production and improve healthcare targeting protein-based drugs.
A WVU biomedical engineer is working on a rapid diagnostic tool that can detect tick-borne infections such as Lyme disease via a blood sample on a single chip. The tool uses dielectrophoresis and machine-learning to detect diseases within one to two weeks after onset, reducing the risk of hospitalization and chronic conditions.
Researchers at Penn State and the University of Arizona are developing biotechnology foundations that employ synthetic anaerobic bacteria to capture and convert methane. The goal is to create scalable biological reactors that can harness methane before it escapes to the atmosphere, producing electricity or valuable chemicals.
Researchers have developed a new framework using high-throughput 'omics' technologies to detect the effects of ambient chemical mixtures on living organisms, including water fleas. The approach enables water fleas to detect bioactive components and predict toxicity in other species.
Researchers at POSTECH have developed a method to engineer organs at scale using bioprinting, overcoming previous limitations of small tissue size and functional complexity. This innovation holds promise for personalized treatment of patients with the potential to create more realistic engineered organs.
A University of Houston engineer has developed a sprayable ice-shedding material that is 100 times stronger than any others. The new durable coating material controls interfacial fractures and can accelerate crack formation and growth.
Researchers analyzed the knowledge of chemical space between 1800 and 1869 to discover how well the periodic table corresponds to the chemical data at its formulation. They found that the periodic table's basic structure was already encoded in space by the 1840s, two decades before its creation.
A Rutgers team designed a synthetic protein that quickly detects molecules of VX, a deadly nerve agent classified as a weapon of mass destruction. The protein can detect VX at levels a thousand times more sensitive than current technologies, with no false positives.
Researchers developed a strain-promoted alkyne-azide cycloaddition strategy to engineer circular bivalent aptamers, improving their stability, recognition, and binding abilities. This method enables the design of new aptamer-based targeted drug delivery strategies and cell behavior regulation techniques.
Researchers at Gladstone Institutes and UCSF have developed a new approach to introduce long DNA sequences into cells with remarkable efficiency. The technology, which uses single-stranded DNA templates, overcomes the limitations of traditional viral vectors and has the potential to make cell therapies faster, better, and less expensive.
A University of Houston engineer has developed technology to determine which patients are likely to respond to CAR T-cell therapy for lymphoma, saving time and increasing success rates. The TIMING method analyzes interactions between T cells and tumor cells, identifying a key ligand molecule that predicts patient response.
A Purdue University chemical engineer has improved upon traditional methods to produce off-the-shelf human immune cells that show strong antitumor activity. The new method, developed by Xiaoping Bao, mass-produces CAR-neutrophils from human pluripotent stem cells with superior and specific antitumor activities against glioblastoma.
Researchers at Gladstone Institutes developed a tool called Retro-Cascorder, which logs a cell's genetic activity for days at a time. This allows scientists to create living biosensors that can record changes to their environment.
Indiana University researchers have discovered the world's brightest-known fluorescent solid materials, called SMILES, which can transform liquid materials into stable crystalline solids with unprecedented brightness. The grant will help advance research on SMILES to improve existing technologies and create new ones.
Researchers demonstrated how heterogeneous photocatalysis can improve selectivity in organic transformations, breaking down lignin and producing high-quality products. The technique offers mild conditions for chemical reactions, using air as the oxidant and ambient pressure, reducing energy consumption and environmental cost.
Wind-dominant electric grids face challenges in recovering from blackouts. Researchers at Iowa State University have developed grid-forming controllers and stall-prevention systems to enable certain wind turbines to blackstart a power grid. This critical step enhances the resilience of wind farms to blackouts.
A WVU engineer is collecting large-scale biometric data using images and videos of faces, gait, body shape, and type. The goal is to improve human recognition performance in challenging conditions.
Researchers at Gladstone Institutes and UC San Francisco have developed a comprehensive rule book for designing therapeutic cells with improved specificity and safety. The new receptor system, dubbed SNIPRs, is small enough for cost-effective engineering into human cells and can detect and respond to even small amounts of its target. T...
Seismologists have developed methods to take wave signals from seismometers and reverse engineer features of the medium they pass through, known as seismic tomography. A new full-waveform inversion model uses 3D wave simulations and data sensitivities at the global scale to improve the resolution of current seismic models.
Researchers found that high-speed shearing enhances chemical reactions by accelerating collisions among reactant molecules. The study suggests using a narrow gap between the stator and rotor to eliminate backflow phenomena, improving mixing conditions.
Researchers found blow flies can be used to detect chemical warfare agents and pollutants, providing a safer alternative for investigating environmental contamination. The insects' guts store information about the environment, which can be analyzed using mass spectrometry.
Engineer Thomas Senftle at Rice University has won a prestigious NSF CAREER Award to improve catalysts through machine learning. He will develop open-source models to speed up the development of catalysts with optimized particle/support combinations, aiming to reduce unwanted molecules in water.
Researchers have found direct evidence of strong electron correlation in ABC trilayer graphene, a two-dimensional material that can switch between metal, insulator, and superconductor states. The discovery provides insight into the underlying physics driving these switchable materials.
Scientists have developed a genetic screening platform to identify genes that enhance immune cells' persistence and ability to eradicate tumor cells. By combining these genes with existing CAR-T cell therapy, researchers were able to engineer T cells that are more effective at eliminating tumor cells.
The Texas cold snap highlighted the critical role of electricity in society and the need for improved power system planning to withstand extreme weather events. The event showed that traditional planning based on historical weather patterns is not sufficient, and new information from climate projection models is needed.
Researchers at UMass Amherst developed a new theory that allows for precise prediction of soft material failure. The breakthrough has major implications for polymer engineering and manufacturing, enabling the design of more efficient products.
A chemical used in electric vehicle batteries can also power rockets and satellites, reducing CO2 emissions and requiring less storage. The new fuel, ammonia borane, releases more energy than traditional hydrocarbon fuels and has no environmental impact.
Rice University physicists have developed a technique to engineer Rydberg states of ultracold strontium atoms, creating 'synthetic dimensions' that simulate real materials. This breakthrough enables the creation of interacting particles in a controlled environment, paving the way for new physics and material properties.
Xue Sherry Gao has won a prestigious CAREER Award to create versatile toolkits for controlling gene expression. Her research aims to develop broadly applicable platforms for gene regulation, with a focus on precision dosing and safety features.
Stanford researchers have made a breakthrough in developing protein circuits that can enable cell-to-cell communication, mimicking the natural process of cells interacting with neighboring cells. The new platform, RELEASE, allows proteins to be secreted and displayed on the cell surface, enabling cells to respond to these signals.
Harris Wang, a synthetic and systems biologist at Columbia University, received the Vilcek Prize for Creative Promise in Biomedical Science for his development of tools to track and engineer microbes. His research aims to improve diagnostic and therapeutic applications using genomic technologies.
Researchers developed Inducible Directed Evolution (IDE), a new technique for controlling directed evolution in bacteria, allowing up to 30 gene modifications at a time. This approach enables finely tuned changes to bacteria, making it suitable for biopharmaceutical and chemical manufacturing industries.
The study reveals that particles can behave as bosons in one region and fermions in another, leading to striking phenomena like particle trapping or fragmentation. This discovery opens up a window to engineer and control new kinds of collective motion in the quantum world.
The global chemical industry aims to recover from the pandemic while addressing consumer demand for sustainable products. Investments in carbon capture and clean technology will continue to rise, while companies rethink packaging and manufacturing methods to reduce waste.
A clinical trial will test a treatment strategy using a lightweight, wearable robotic device that provides neuromuscular training and makes walking easier for children with cerebral palsy. The study aims to establish fundamental knowledge on adaptive ankle interventions to treat walking impairment relative to standard of care.
A team of researchers demonstrates an adaptive optimization protocol that can engineer arbitrary high-dimensional quantum states, overcoming limitations due to noise and experimental imperfections. The protocol uses measured agreement between produced and target state to tune experimental parameters.
Marquette University has received a two-year, $3.8 million grant from the U.S. Department of Defense to develop novel technologies for protecting the environment and providing clean drinking water. The 'In Defense of Water' program will focus on four areas: water reuse, disinfection, PFAS removal, and water data fusion.
Engineered biofilms made of E. coli bacteria exhibit emergent drug resistance properties when printed using the new technique. This study provides valuable insights into harnessing the beneficial aspects of biofilms while combating their negative effects, potentially leading to breakthroughs in medicine and materials science.
A new report from Portland State University aims to improve mobility and quality of life for older adults by developing forms of assistance and educational strategies. The study found that low-income older adults faced significant barriers to transportation, including fear of public transit during the pandemic lockdowns.
Researchers developed a machine learning method to assign NMR spectra of organic crystals probabilistically from their 2D chemical structures. The approach uses a database of chemical shifts for organic solids, reducing computational cost by up to 10,000 times compared to current methods.
Physicists from Exeter and Zaragoza develop a theory to engineer non-reciprocal flows of quantum light and matter, paving the way for novel devices with directional character. This breakthrough may lead to the creation of quantum technologies requiring efficient, directional energy transfer.
A team at Sandia National Laboratories tested specially designed stainless-steel containers for fire safety and found they did not split open even when heated to 2000 degrees Fahrenheit. The containers developed small pinholes instead, allowing superheated gas to escape without pressurizing the container.
Researchers at Rice University developed a method to decontaminate disposable surgical masks by heating them to 70 degrees Celsius, eliminating 99.9% of the SARS-CoV-2 virus and preserving mask material. The study provides promise for adapting this protocol to future outbreaks.
Researchers at Aarhus University have discovered how plant receptors recognize specific carbohydrate signaling molecules from their bacterial symbionts. The ability allows plants to select and accommodate nitrogen-fixing bacteria inside their roots.
Researchers at UTA explore artificial ferroelectric materials to engineer smart mechanical behaviors using light and machine learning. They plan to create tunable free energy landscapes with varied materials and thicknesses, paving the way for various applications.
University of Delaware chemical engineer Catherine Fromen aims to improve the delivery of therapeutic medicines to the body by studying how they interact with mucosal interfaces. Her research focuses on designing medicines that can overcome natural defenses in the lungs and gut, with potential applications for diseases such as lung can...
A team of scientists at Brookhaven National Laboratory has identified a key component of the assembly line responsible for oil droplet formation. The study suggests new ways to engineer plant tissues for increased oil accumulation, which could lead to sustainable oils for biofuels and other commodity products.
Researchers have developed a new interface technology that can provide natural sensory feedback from robotic prosthetics to amputees, reducing abnormal sensations and cognitive burden. The innovation uses ultra-small recording sites and molecular guidance cues to stimulate sensory axons selectively, improving control of robotic limbs.
A chemical engineer is developing a novel biomaterial that can mimic the response of pediatric brain cancers to different approaches, allowing for customized treatment plans. The material will be designed to simulate the growth environment of cancer cells inside a tumor and can be used with patient-derived cells.
A new framework from Cornell University's Fengqi You and Xiang Zhao provides a comprehensive analysis of the environmental impacts of plastic waste chemical recycling. The framework quantifies climate change and human toxicity, offering insights into optimal technologies and market dynamics.
Researchers developed a theoretical model to predict the strength of millions of alloys at high temperatures. Experiments confirmed the predictions, highlighting the importance of edge dislocations in determining yield strength in complex high-entropy alloys.
The Center for Research on Programmable Plant Systems (CROPPS) aims to integrate plant sciences, engineering, and computer science to improve crop efficiency and sustainability. Researchers will engineer plants that can detect environmental changes and respond to digital signals, leading to more efficient water and nutrient delivery.
A compact CasMINI CRISPR system has been engineered for efficient gene regulation and editing in mammalian cells. The system, derived from the naturally occurring archaeal protein Cas12f, is highly specific and efficient, making it suitable for various therapeutic applications.