A new imaging agent has been developed to identify cancer cells and their supporting compromised cells. The compound binds to activated annexin A2 protein present in many solid tumors, allowing for targeted imaging and potential dual targeting of the tumor and surrounding cells with chemotherapy drugs.
Researchers have created a device that uses sound waves to produce high-resolution images of the human brain, potentially revolutionizing brain imaging. The technology could be suitable for continuous monitoring of high-dependency patients and overcome obstacles with current MRI methods.
A team of researchers has created a novel photoacoustic imaging method that can penetrate up to 3.4 cm into deep tissues using a nickel-based nanoparticle contrast agent. This advancement enables the visualization of deep organs without causing harm or using ionizing radiation, paving the way for improved clinical diagnosis and practices.
A new study from the Joslin Diabetes Center reveals that ultra-wide field (UWF) fluorescein angiography detects over three times more microaneurysms than UWF color imaging, highlighting the need for cautious use of these techniques when evaluating and treating diabetic retinopathy. The research also suggests that AI can automate the gr...
COVID-19 imaging features exhibit variable and nonspecific characteristics, but also share similarities with those of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). Initial chest imaging abnormalities are common, affecting at least 85% of patients, often displaying bilateral lung involvement.
A new radiopharmaceutical, [55Co]Co-DOTATATE, has been developed to aid in the diagnosis of neuroendocrine tumor metastases. It resulted in superior image contrast and enhanced detection compared to commonly used imaging agents.
The Beckman Institute has developed imaging techniques that capture more information about a tissue compared to traditional methods, allowing for better visualization of extracellular vesicles. These vesicles are known to increase in number and be associated with cancer, particularly breast cancer cells.
A new form of imaging modality called coded light-sheet array microscopy (CLAM) allows for full 3D parallelized fluorescence imaging without scanning. CLAM reduces photobleaching and preserves biological specimen viability, enabling long-term volumetric imaging.
Researchers have identified several potentially useful breast cancer biomarkers that indicate the presence and risk of malignancy. PET/MRI imaging revealed differences in biomarkers between healthy contralateral breast tissue of patients with malignant and benign breast tumors.
Researchers developed a new laser-based system that can image around corners in real time, enabling applications such as detecting hazards or pedestrians in self-driving cars. The system uses deep learning to reconstruct hidden objects at high resolutions and speeds.
A recent study found that low back pain accounts for approximately one-third of new emergency department imaging in the US. Imaging utilization varies significantly by region, with patients in the southern US undergoing more imaging than those in the western US.
A Chinese research team has developed a new technique that enables super-resolution microscopy of living cells with unprecedented speeds and resolutions. The approach, which combines ghost imaging and compressive imaging, can capture processes in living cells on millisecond time-scales with spatial resolution of tens of nanometers.
Researchers used ghost imaging to enhance the speed of super-resolution microscopy, achieving nano-scale resolution in just 10 image frames. The new approach resolves structures with spatial and temporal resolutions at which biological processes take place.
Ghost imaging allows forming images with lower light levels but has been limited to stationary objects due to blurring from movement. Researchers developed a new method combining blurry image information with object location data to capture high-quality images of moving objects using ghost imaging.
Researchers developed a novel noninvasive imaging technique using multispectral optoacoustic tomography (MSOT) and ultrasound to diagnose thyroid disorders. MSOT/ultrasound images revealed significant biomarker changes in Graves' disease and malignant thyroid nodules, showing promise for improved diagnostics.
Researchers developed a machine learning method to enhance optoacoustic imaging quality without sacrificing it. The approach uses sparse data, allowing for reduced sensor numbers and improved diagnosis accuracy, facilitating clinical decision-making.
Researchers used state-of-the-art brain imaging techniques to study nonverbal children with autism, finding delayed responses to simple auditory tones. The study suggests that measuring brain activity in the auditory cortex could serve as important objective markers for response to sound.
Nonphysician providers, including nurse practitioners and physician assistants, rarely render diagnostic imaging services, with most being radiography and fluoroscopy. Despite growing involvement in imaging-guided procedures, NPPs still represent a small fraction of all diagnostic imaging interpretations.
Boston Children's Hospital scientists have received funding from the Chan Zuckerberg Initiative to support two projects focused on mapping specific tissues and improving imaging tools. The grants will help advance understanding of childhood diseases and develop better therapies.
The American Society of Nuclear Cardiology published expert consensus recommendations for multimodality imaging in cardiac amyloidosis, aiming to improve diagnosis and management. The guidelines unify standardized imaging methods, diagnostic criteria, and appropriate utilization across various imaging modalities.
A recent study analyzed over 135 million imaging exams across the US and Ontario, finding that medical imaging rates have continued to increase despite campaigns to reduce their use. The study found a reacceleration in imaging use for CT and MRI scans in adults, with ongoing growth in both countries.
A new study found that medical imaging rates have continued to increase in the US and Ontario, Canada, despite a campaign to reduce their use. The study analyzed over 135 million imaging exams and found that CT and MRI use have grown in most age groups, with a notable decline in children.
The study analyzed 135 million imaging examinations among 16-21 million patients in the US and Canada, finding increased medical imaging rates among adults but declining nuclear medicine use. Imaging rates continued to rise among children except for CT, which declined since 2006.
Researchers have developed a way to enhance the imaging speed of two-photon microscopy up to five times without sacrificing resolution. By combining compressive sensing with a faster scanning method, scientists can now observe biological phenomena that were previously too fleeting to image with current state-of-the-art microscopy.
A network of national imaging centers is proposed to facilitate collaboration and innovation in biological imaging. The centers will provide spaces for interdisciplinary interactions, enabling the development, application, and teaching of advanced biological imaging techniques.
Researchers developed a new method using frequency domain measurement in functional near infrared spectroscopy (fNIRS), improving image quality and spatial resolution. This innovation enables enhanced brain imaging with greater depth sensitivity, paving the way for more accurate neuroimaging applications.
Researchers at Macquarie University have created a simple method to bypass diffraction limitations using standard optical imaging tools, enabling everyday bio-imaging techniques. The uSEE approach improves resolution by reducing illumination intensity, making it suitable for any biological lab with minimal extra cost.
A Belgian team developed a two-in-one contrast agent for medical imaging, combining MRI and photoacoustic imaging techniques. The bimodal probe enhances sensitivity while minimizing risks for patients.
A multidisciplinary team at Kaiser Permanente developed a complete imaging history definition, including four prompts for date, location, pain, and concern. This led to a significant increase in orders containing all four components, from 16% to 52%, and improved mean character count of entered histories.
Researchers from the University of Wisconsin-Madison and Universidad de Zaragoza have successfully developed a method to image complex hidden scenes using a projected virtual camera. This technology can overcome current limitations in non-line-of-sight imaging, including varying material qualities and large variations in brightness. Th...
A new imaging technique uses magnetic properties of the heart muscle to quantify changes in blood flow, identifying areas impacted by coronary atherosclerosis. This method eliminates the need for contrast agents or pharmacological stress tests, offering a faster and potentially safer diagnostic option for CAD patients.
A new international consensus document provides guidelines for the conduct of magnetic resonance imaging studies after a myocardial infarction. The main outcome measure recommended is absolute infarct size, with scanning timing between 3 and 7 days post-infarction.
A study published in JAMA Oncology found that introducing a default physician order into electronic health records reduced daily imaging for cancer patients with advanced cancer by half. This change also saved an average of two minutes per session, resulting in faster treatment courses.
The Journal of Nuclear Medicine has seen a significant increase in its impact factor, with a jump of 25% compared to the previous year. The journal's immediacy index also increased, indicating a faster pace of citation activity.
The Society of Nuclear Medicine and Molecular Imaging announced 13 new SNMMI Fellows, recognizing their outstanding contributions to the field. The recipients include past SNMMI presidents and experts in various areas of nuclear medicine and molecular imaging.
A new class of radiopharmaceuticals, named radiohybrids (rh), has been developed for cancer imaging and radioligand therapy (theranostics). These rhPSMA-ligands have a unique feature that both fluorine and the metal are always present, but only one of them is present as a radioactive isotope.
A first-in-human Phase 1/Phase II study demonstrates the safety and efficacy of intravenous administration of technetium-99m tilmanocept for monitoring rheumatoid arthritis disease activity. The imaging agent binds to activated macrophages, providing joint-specific information on RA disease involvement.
Jason S. Lewis, PhD, has received the 2019 Paul C. Aebersold Award from the Society of Nuclear Medicine and Molecular Imaging (SNMMI) for his outstanding contributions to basic nuclear medicine science. His research focuses on developing radiopharmaceuticals for targeted diagnosis and treatment of cancer.
Researchers at UNC Lineberger Comprehensive Cancer Center discovered a new way to attach Fluorine-18, a widely used PET imaging isotope, to existing compounds. This breakthrough enables the creation of novel PET agents from existing drugs, opening up possibilities for tracking pharmaceuticals and diagnosing diseases like cancer.
Researchers have demonstrated a new imaging modality that accurately evaluates plaque-based cholesterol, allowing for more timely treatment of atherosclerosis. The technology combines laser photoacoustics and frequency-domain signal processing to detect cholesterol in arterial plaque.
A new study from McGill University and the University of Antwerp has developed a PET imaging platform that allows simultaneous scanning of multiple awake animals. This breakthrough enables unprecedented experimental designs and opens up new avenues for research into brain function, neurochemistry, and behavior.
The expert consensus paper recommends using intracoronary imaging to guide treatment for acute coronary syndromes, including heart attacks. Imaging provides a more accurate diagnosis and helps tailor therapy, especially for younger patients with complex lesions or plaque erosion.
The EAPCI has generated consensus statements detailing the clinical utility of IC imaging, based on existing clinical evidence and contemporary best practice. IC imaging is beneficial for guiding percutaneous coronary interventions (PCI) and understanding stent failure mechanisms.
A novel imaging technique using scorpion venom-derived protein BLZ-100 has shown promise in detecting and removing brain tumors. The agent binds to tumor cells and glows under near-infrared laser stimulation, enhancing surgical visualization. Clinical trials demonstrate the imaging system's safety and effectiveness.
Imaging techniques like cardiac MRI and intravascular imaging can help diagnose the underlying cause of MI in women without obstructive CAD. These methods provide crucial information for treatment decisions.
The article discusses the importance of multimodality imaging training for general and advanced cardiology fellowships. The ideal training models remain undetermined, leaving uncertainties about manpower needs and cardiologist expertise.
A new imaging technique using subharmonic contrast-enhanced ultrasound may help detect prostate cancer in patients where MRI is negative. The study, to be presented at the ARRS Annual Meeting, found that the technique detected PCa in 9 of 31 patients with a prior negative MRI or biopsy.
A study found that clinicians over-order imaging for breast pain, despite a weak correlation with breast cancer. Most respondents (72%) believe there is no strong link between breast pain and breast cancer.
Researchers developed a capsule-shaped photoacoustic imaging endoscope to examine intestinal changes in Crohn's disease. The device can differentiate between inflammatory and fibrotic strictures, allowing for more targeted treatment and potentially reducing adverse effects. This technology could also provide real-time diagnostic inform...
Researchers at Caltech Optical Imaging Laboratory created a technique to break the acoustic diffraction limit in PACT by localizing single dyed droplets flowing in blood vessels, achieving six-fold finer resolution. The droplets provide excellent tracers for super-resolution imaging and enable tracking of blood flow speed.
A workshop published a roadmap for AI in medical imaging, highlighting key research themes and prioritizing foundational machine learning research. The report emphasizes the need for collaboration among professionals, funding agencies, and institutions to develop innovative imaging technologies.
Researchers at the University of Houston are developing a new imaging technology that can simultaneously capture structural and molecular changes in embryos during critical periods of development. This breakthrough could lead to improved early detection and prevention of birth defects with long-term chronic conditions.
Researchers have discovered a new PET imaging biomarker that can better predict the progression of Alzheimer's disease. Microglial activation levels, as measured by TSPO-PET imaging, showed a significant correlation with cognitive outcomes in an amyloid mouse model.
A new study found that patient factors, including distance from hospital, age, and health insurance status, significantly impact follow-up imaging rates. The study also showed disparities in follow-up rates among different age groups, with younger and older patients having lower completion rates.
A Northwestern University research team has developed tiny, fully reconfigurable metalenses made from silver nanoparticles that can adapt to different imaging applications. The new lenses have a thickness 100 times smaller than human hair and can form multiple images at various positions.
The Ryerson-led research team developed a technique called F-Mode, which enables selective enhancement of features in biological structures based on size. This breakthrough has significant potential in ophthalmology, neurosurgery, and disease detection.
Researchers developed a new 'multi-z' confocal microscopy system for imaging large groups of cells, enabling fast and detailed imaging across a wide field of view. The instrument captured cellular details at high speeds over a large 3D volume, providing unprecedented insights into how neurons interact during various behaviors.
Diattenuation Imaging enables precise investigation of brain tissue by measuring polarization-dependent attenuation of light. The method distinguishes between regions with thin and thick nerve fibers, aiding in the study of neurodegenerative diseases like multiple sclerosis.
The Marine Biological Laboratory (MBL) has received a $17 million award from the Chan Zuckerberg Initiative to fund a new imaging scientist. This funding will support the development of new imaging technologies and drive biological discoveries.
Researchers repurposed an algorithm from Netflix's movie preference prediction competition to create a method for acquiring classical Raman spectroscopy images of biological tissues at unprecedented speeds. This advance could make the simple, label-free imaging method practical for tumor detection or tissue analysis.