A lack of government action on NHS staffing undermines efforts to diagnose cancer early, with nearly half of all cancers diagnosed in England at stage 3 or 4. The health service needs an extra 1,700 radiologists and nearly 2,000 therapeutic radiographers to improve staff efficiency.
Research funded by Cancer Research UK found that average monthly cigarette consumption fell by 24.4% based on survey data and 24.1% based on sales data between 2011 and 2018. The decline suggests that stricter tobacco laws and quitting smoking initiatives are working, with current smoking rates at 16% of English adults.
Researchers discovered an antibody drug that can destroy immune cells surrounding solid tumours, allowing T-cells to attack and kill cancer cells more effectively. The approach could improve treatments for various types of cancer, including CAR-T therapy.
A Cancer Research UK-funded study found that less chemotherapy is as effective at controlling disease for elderly or frail patients with advanced stomach or oesophagus cancer. The study showed that lower doses of chemotherapy resulted in fewer side effects and improved quality of life.
A large study found that HER2 expression can predict DCIS recurrence and progression, enabling targeted treatments for high-risk patients. By screening DCIS patients for HER2, doctors can minimize the chance of recurrence or spread in lower-risk patients.
Researchers have developed a blood test that can identify genetic faults in cancer patients' blood, enabling clinicians to select targeted treatment options. The study showed that 11 out of 100 patients were successfully matched with molecularly matched clinical trials.
A recent study by Cancer Research UK reveals that African-American cancer patients with inherited red blood cell conditions are 20% more likely to experience serious adverse events. This disparity may be attributed to the rigors of therapy and the disproportionately higher incidence of these disorders in the African-American population.
Scientists have developed a statistical tool to predict breast cancer recurrence and progression, using molecular patterns from nearly 2000 women. The research identified distinct clinical trajectories for different breast cancer subtypes, highlighting the importance of personalized treatment options.
A study of over 675,000 cancer patients found that those with a psychiatric history were 73% more likely to die from their cancer. The risk increased with the level of psychiatric help, suggesting that stress may affect the body's biological systems.
A new study by Cancer Research UK found that smokers with melanoma are 40% less likely to survive than non-smokers. Researchers believe smoking may disrupt the immune system's ability to fight cancer.
A new study suggests that recurring infections could lead to delayed diagnoses of bladder or kidney cancer in women. Analysis of over 100,000 people found that many with blood in their urine had no check-up after initial UTI symptoms.
A study found that social stigmas surrounding HPV can make women anxious about their health and put them off cervical screening. The new HPV screening method aims to address these concerns by providing a more accurate diagnosis, reducing the risk of false positives, and improving patient confidence.
Cancer researchers have mapped oesophageal adenocarcinoma genes in unprecedented detail, unveiling more than half as potentially targetable by drugs already in trials for other cancers. This breakthrough could lead to personalized therapies and improved treatment options for patients.
Scientists have found that invasive skin cancer molecules reprogram healthy immune cells, allowing the cancer to spread. Researchers discovered that blocking certain chemicals can help prevent the aggressive skin cancer from coming back after treatment.
Researchers developed a new way to predict breast cancer risk by combining genetics, family history, weight, age at menopause, alcohol consumption, and hormone replacement therapy. The online calculator can identify different risk groups and inform tailored screening and preventative therapy.
Researchers are developing a breath test to detect cancer at an early stage by analyzing volatile organic compounds in the breath. The PAN Cancer trial aims to identify patterns of VOCs that could indicate the presence of different types of cancer.
Two new studies published in the British Journal of Cancer reveal alarming breast cancer risks for women with false-positive screening results. Women who experience a first false-positive result have a two-fold risk of developing screen-detected or interval breast cancer later in life, while those with a second false-positive result fa...
A recent study found that around 72% of women at higher risk of breast cancer are worried about the long-term effects of tamoxifen, while 57% believe it will give them unpleasant side-effects. Despite its proven ability to prevent breast cancer, fewer than 15% of women with discussed preventive therapy are taking tamoxifen.
Scientists have developed a new technique to extract biomolecules from blood samples, which could lead to early diagnosis, drug discovery and personalized medicines. The method uses liposomes to detect a wide variety of biomolecules, overcoming the challenge of amplifying cancer signals in the presence of noise.
A study found that restricting cancer cells' ability to metabolize sugar makes oncolytic viruses work better, multiplying faster and destroying cancer quicker. This approach may improve how potential cancer drugs are investigated in the lab.
Researchers have discovered that dasatinib sensitizes triple negative breast cancer cells to chemotherapy by targeting breast cancer stem cells. Additionally, a systematic review and meta-analysis found an increased risk of second cancers at sites associated with HPV after a prior HPV-associated malignancy.
Researchers found that it took a year or more from first spotting a symptom to beginning treatment for 10% of patients in England, Northern Ireland, and Wales. The time to diagnosis varied significantly across countries, with Denmark performing the best.
A lab study funded by Cancer Research UK and Worldwide Cancer Research found that mannose can slow tumour growth and enhance the effects of chemotherapy in mice with multiple types of cancer. The researchers discovered a dosage of mannose that could block enough glucose to slow tumour growth in mice without affecting normal tissues.
A recent study published in the British Journal of Cancer found a positive association between type 2 diabetes and an increased risk of colorectal cancer (CRC) in men, with a moderately higher risk observed. In contrast, the association was weaker and not statistically significant for women. The study followed up over 87,000 women and ...
Researchers have successfully detected brain tumor DNA in cerebrospinal fluid (CSF) using a cheap and widely available technique, opening up new possibilities for monitoring and treating brain tumors. The test has the potential to increase detection rates and provide more tailored treatment approaches for patients with brain tumors.
A new study by Cancer Research UK has found that immune cells in urine samples can accurately reflect the tumor environment, offering a non-invasive window into bladder cancer. This discovery could help monitor response to immunotherapy and identify patients most likely to benefit from treatment.
Cancer Research UK has partnered with Italian and Spanish charities to invest in six international collaborations worth approximately £30 million. The projects aim to accelerate progress in translational research by investigating immunotherapies, CAR-T cell production, and developing blood tests for advanced prostate cancer.
Despite the risk of a 25% lower mortality rate, many people aged 60 and above are missing out on lifesaving bowel cancer screening. Inequalities in the system have widened, with those from deprived areas and ethnically diverse neighbourhoods being less likely to participate.
Research reveals up to 13% higher proportions of emergency hospital visits among bowel cancer patients living in the most deprived areas, with nearly half experiencing an emergency visit compared to a third of those from less deprived backgrounds. Improved access to healthcare and screening programs may help reduce these disparities.
Researchers have identified a blood biomarker called KIM-1 that can predict the risk of developing kidney cancer over the next 5 years. Measuring levels of KIM-1 in the blood may help detect kidney cancer earlier, potentially improving survival rates.
Scientists have found that internal mammary chain irradiation and anthracycline-based chemotherapy increase cardiovascular disease risks, while a new test may detect colorectal cancer in primary care. Researchers also discovered circulating tumor cell clusters in human glioblastoma, suggesting a new target for treatment
Researchers discovered that cancerous cells in an aggressive type of childhood brain tumour work together to infiltrate the brain. The study found that DIPG cells can exert a profound influence on each other, leading to tumour growth and spread.
Researchers have found that giving sodium thiosulphate after chemotherapy reduces hearing loss in children treated for hepatoblastoma, a childhood liver cancer, by nearly 50%. The treatment is a major step forward in minimizing long-term side effects and offers hope to families affected by the debilitating condition.
New research funded by Cancer Research UK found that people using high nicotine e-liquid puffed less deeply and often than those using low nicotine liquid. The study also showed that high nicotine vapers had lower levels of toxic chemicals in their vapour compared to low nicotine users.
Breast cancer patients aged 70 and over in England have a higher risk of mortality due to reduced surgical intervention compared to other countries. Patients with stage three breast cancer in England are also more likely to not receive surgery, which has been linked to poorer survival rates.
Researchers found that an antifungal medication can halt the growth of dormant cells within bowel tumours in mice. The study suggests that this drug could be effective in treating advanced bowel cancer by targeting drug-resistant cells.
A study published in the British Journal of Cancer found that men with testicular cancer who underwent vigorous exercise improved their energy levels and self-esteem. High-intensity interval training was particularly effective in reducing tiredness and improving overall vitality.
The £18 million Brain Tumour Awards aim to advance understanding of brain tumours and develop new treatments. The awards focus on six major themes, including unlocking insights into brain tumour biology, developing more accurate diagnostic methods, and improving treatment approaches for patients.
A survey found that over 40% of people in England believe stress, food additives, and electromagnetic frequencies cause cancer despite a lack of scientific evidence. Those with better knowledge of proven cancer causes were more likely to make healthier lifestyle choices.
A study found that only one in seven high-risk women take tamoxifen for breast cancer prevention, with social class, education, and ethnicity not affecting uptake. Women chose not to start taking the drug due to fears about its impact on their family and health.
A Cancer Research UK landmark study found that smoking remains a major preventable cause of cancer, accounting for 32,200 cases in men and 22,000 in women. Excess weight is also a significant risk factor, with over 22,800 cases attributed to being overweight or obese annually.
A recent trial found that a one-off PSA test does not save lives in asymptomatic men, highlighting the need for more accurate ways to diagnose aggressive prostate cancers. The study of over 400,000 men aged 50-69 showed no significant difference in mortality rates between those who were screened and those who were not.
Researchers found that restricting asparagine production in mice greatly reduced breast cancer's ability to spread, suggesting a potential new treatment approach. The study also suggests that dietary changes may help stop cancer from spreading and improve outcomes for patients.
A study by Cancer Research UK found that teens who watch TV with adverts are more likely to eat unhealthy foods like crisps, biscuits, and fizzy drinks, consuming up to 500 extra snacks a year. The report suggests that reducing junk food TV marketing could help halt the obesity crisis.
The NHS bowel scope screening programme saw a significant increase in uptake when patients were sent additional reminders addressing common concerns, highlighting the importance of patient information and support., Bowel cancer is the 4th most common cancer in the UK, with over half of cases diagnosed at a late stage.
New research reveals how alcohol causes permanent genetic damage to blood stem cells, leading to cancer. The study found that acetaldehyde breaks and damages DNA within these cells, altering chromosome sequences and increasing the risk of certain cancers.
A Cancer Research UK study found that health warnings on cigarette packaging can significantly reduce the likelihood of young people trying cigarettes. The study revealed that young people were around three times less likely to want to try cigarettes with a health warning compared to standard cigarettes.
Researchers found that a blood test for tumour DNA can predict the likelihood of aggressive skin cancer returning, with 33% of patients who tested positive being alive after five years compared to 65% of those who didn't. The study also revealed that patients with faults in genes BRAF and NRAS are more likely to experience a return wit...
A Cancer Research UK-funded study found that combining anti-CD27 and anti-CD20 antibodies increases life expectancy in mice with cancer by nearly doubling the median survival time. The combination recruits more immune cells and enhances their ability to destroy cancer cells, offering a promising new approach to treating lymphoma.
A new study suggests that HPV vaccination can reduce the number of cervical screens needed from 12 to just three for vaccinated women. The research also recommends seven lifetime screens for unvaccinated women.