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Columbia University School of Engineering and Applied Science


Precipitation will be essential for plants to counteract global warming

A new study from Columbia University reveals that the balance between soil water and energy availability determines whether plant growth is limited by precipitation or temperature. This finding highlights the crucial role of precipitation in supporting plant photosynthesis, particularly during the late growing season.

SourceColumbia University School of Engineering and Applied Science·JournalProceedings of the National Academy of Sciences·DateApr 13, 2020

Compact beam steering studies to revolutionize autonomous navigation, AR, neuroscience

Researchers have developed a low-power beam steering platform that enables scalable optical systems for ultra-small LiDAR on autonomous vehicles, AR/VR displays, trapped-ion quantum computers, and optogenetics. The technology reduces power consumption while maintaining operation speed and broadband low loss.

Columbia researchers develop new method to isolate atomic sheets and create new materials

Researchers at Columbia University have developed a new method to isolate atomic sheets from layered van der Waals crystals, producing large-area atomically thin layers with high quality. The monolayers can be stacked in any desired order and orientation to generate a whole new class of artificial materials.

Designer probiotic treatment for cancer immunotherapy

Researchers have designed a novel probiotic strain that can seek out solid tumors and safely deliver immune checkpoint inhibitors, leading to tumor regression. The probiotic platform can also be used to deliver multiple immunotherapies simultaneously, enabling effective therapeutic combinations for difficult-to-treat cancers.

SourceColumbia University School of Engineering and Applied Science·JournalScience Translational Medicine·DateFeb 12, 2020

Robotic trunk support assists those with spinal cord injury

A Columbia Engineering team has invented a robotic device called the Trunk-Support Trainer (TruST) that can help people with spinal cord injuries sit more stably. The study found that TruST enabled patients to expand their active sitting workspace by an average of 25%, improving their trunk control and balance limits.

SourceColumbia University School of Engineering and Applied Science·JournalSpinal Cord Series and Cases·DateJan 5, 2020

Breaking (and restoring) graphene's symmetry in a twistable electronics device

Researchers at Columbia University have developed a new way to control the properties of two-dimensional materials by adjusting the twist angle between them. By creating multiple moiré patterns in a graphene-boron nitride device, they were able to study the effects of coexisting moiré superlattices on a layer of graphene.

New clues as to why mutations in the MYH9 gene cause broad spectrum of disorders in humans

Researchers used in vivo imaging to observe how cells move and generate forces in living tissues, revealing new clues on why MYH9 gene mutations lead to various diseases. The study demonstrates that altered myosin activity results in defects in epithelial morphogenesis due to slower cell movements.

SourceColumbia University School of Engineering and Applied Science·JournalProceedings of the National Academy of Sciences·DateOct 28, 2019

New feedback phenomenon found to drive increasing drought and aridity

A new study found that concurrent soil drought and atmospheric aridity are driven by land-atmosphere processes and feedback loops, leading to increased frequency and intensity of extreme events. The researchers warn that future intensification of these events would be disastrous for ecosystems and human lives.

SourceColumbia University School of Engineering and Applied Science·JournalProceedings of the National Academy of Sciences·DateSep 2, 2019

Robotic cane shown to improve stability in walking

Researchers at Columbia University School of Engineering developed a robotic cane that provides light-touch assistance in walking, improving stability and balance. The device, called CANINE, acts as a mobile assistant to track a person's gait and provide support, resulting in narrower strides and increased gait stability.

SourceColumbia University School of Engineering and Applied Science·JournalIEEE Robotics and Automation Letters·DateAug 6, 2019

Ultrasound method restores dopaminergic pathway in brain at Parkinson's early stages

Researchers developed a novel technique using transcranial ultrasound and microbubbles to open the blood-brain barrier, enabling drugs to penetrate the brain and restore dopaminergic pathways. The method has been approved by FDA for clinical trials in Alzheimer's patients and shows promise for treating Parkinson's disease at early stages.

SourceColumbia University School of Engineering and Applied Science·JournalJournal of Controlled Release·DateJun 6, 2019

New approach shows regeneration of severely damaged lungs

A multidisciplinary team from Columbia Engineering and Vanderbilt University has demonstrated regeneration of severely damaged lungs in a clinically relevant model. The researchers developed a cross-circulation platform that maintained lung viability and function, enabling the recovery of lungs unsuitable for transplant due to injury.

Radical desalination approach may disrupt the water industry

Researchers at Columbia University have developed a novel desalination approach called temperature swing solvent extraction (TSSE) for treating high-salinity brines. TSSE can efficiently remove salt and recover water, with the potential to transform the water industry by reducing energy consumption and costs.

SourceColumbia University School of Engineering and Applied Science·JournalEnvironmental Science & Technology Letters·DateMay 6, 2019

Defying the laws of physics? Columbia engineers demonstrate bubbles of sand

Researchers at Columbia University have discovered a new family of gravitational instabilities in granular particles, where lighter grains rise through heavier grains like 'fingers' and 'bubbles'. This phenomenon sheds light on geological processes and has potential applications in pharmaceutical production and carbon capture.

SourceColumbia University School of Engineering and Applied Science·JournalProceedings of the National Academy of Sciences·DateApr 22, 2019

Bacterial therapy in a dish

Researchers at Columbia University School of Engineering and Applied Science have developed a system called BSCC, which enables rapid screening of engineered bacterial therapies in vitro. They successfully tested a potent therapy for colon cancer using a novel bacterial toxin combined with an optimal drug delivery genetic circuit.

SourceColumbia University School of Engineering and Applied Science·JournalProceedings of the National Academy of Sciences·DateApr 17, 2019