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DOE/Brookhaven National Laboratory


Structure of 'oil-eating' enzyme opens door to bioengineered catalysts

Researchers at Brookhaven National Laboratory have produced the first atomic-level structure of an enzyme that selectively breaks carbon-hydrogen bonds, suggesting ways to engineer it for producing desired products. The detailed structure reveals how the enzyme operates under ordinary conditions and produces few unwanted byproducts.

SourceDOE/Brookhaven National Laboratory·JournalNature Structural & Molecular Biology·DateMar 30, 2023

AI discovers new nanostructures

Researchers at Brookhaven National Laboratory have successfully discovered new materials using artificial intelligence and self-assembly. The AI-driven technique led to the discovery of three new nanostructures, expanding the scope of self-assembly's applications in microelectronics and catalysis.

SourceDOE/Brookhaven National Laboratory·JournalScience Advances·DateJan 13, 2023

A radical new approach in synthetic chemistry

Researchers use pulse radiolysis experiments to measure how unpaired electrons can drive chemical reactivity on a molecule's opposite side, enabling the creation of novel synthetic methodologies. The study demonstrates the potential for free radicals to influence reactivity beyond their site of origin.

SourceDOE/Brookhaven National Laboratory·JournalJournal of the American Chemical Society·TypeExperimental study·DateNov 23, 2022

Ultrafast 'camera' captures hidden behavior of potential 'neuromorphic' material

Researchers used a mega-electron-volt ultrafast electron diffraction instrument to study vanadium dioxide's insulator-metal transition. The 'stroboscopic camera' captured the hidden trajectory of atomic motion, showing two stages with non-linear atomic motions in the second stage, influenced by electron orbital forces.

SourceDOE/Brookhaven National Laboratory·JournalPhysical Review X·TypeExperimental study·DateMay 9, 2022

Evidence for exotic magnetic phase of matter

Researchers discovered a novel type of magnet, the antiferromagnetic excitonic insulator, which involves strong magnetic attraction between electrons in a layered material. The new state emerges when electrons form bound pairs with holes and trigger an antiferromagnetic alignment of adjacent electron spins.

SourceDOE/Brookhaven National Laboratory·JournalNature Communications·TypeExperimental study·DateFeb 22, 2022

Screening study IDs inhibitor of key COVID virus enzyme

A team of scientists at Brookhaven National Laboratory has identified a molecule with significant potential to disable the COVID-19 virus. The molecule was discovered using high-throughput virtual screening and laboratory experiments, and its ability to bind to the virus's main protease was confirmed through structural studies.

SourceDOE/Brookhaven National Laboratory·JournalJournal of Chemical Information and Modeling·TypeComputational simulation/modeling·DateJan 26, 2022