Rensselaer researchers will use a five-year grant to develop novel inhibitors of the SARS-CoV-2 virus's CLpro and PLpro proteases. The team aims to create an orally bioavailable drug that can be administered at home, with the potential for improved antiviral activity when combined with other drugs like remdesivir.
Researchers at Rensselaer Polytechnic Institute developed an accessible way to make N95 face masks that can kill viruses and bacteria on contact. The antiviral masks use a simple process with widely available tools, reducing plastic waste by allowing for longer wear.
A new theory of decision-making proposes that people often use relative thinking when they should use absolutes, and vice-versa. This theory, developed by Mina Mahmoudi, aims to capture the behavior of boundedly rational decision-makers who struggle with optimal choices.
A naturalistic study using eye-tracking technology found that intensive care unit nurses experience a higher level of mental workload, especially during the start of shifts, with shorter fixation and more sporadic gaze behavior in stressed nurses.
Researchers at Rensselaer Polytechnic Institute found that alternative delivery locations can help offset the negative impacts of increased home deliveries. The study suggests that these locations may be more appealing to underrepresented groups who don't receive many packages, increasing their willingness to use them.
Research found that IVF clinics offering money-back guarantees have a higher live-birth success rate and lower multiple birth risks compared to those without MBGs. The study suggests that these programs serve as signals of high-quality care in the field of IVF and other healthcare services.
Research from Rensselaer Polytechnic Institute found a significant drop in traffic accidents during the COVID-19 pandemic, with accidents involving males, nonwhite drivers, and individuals in the 25-64 age group showing smaller reductions.
Astrophysicists have calculated the original mass and size of a dwarf galaxy torn apart in a collision with the Milky Way billions of years ago. The reconstructed galaxy's stars now stream through the Milky Way, carrying information about its gravitational field.
Research at Rensselaer Polytechnic Institute found that the circadian system influences the immune cells' clearance of Amyloid-Beta 42, a key protein linked to Alzheimer's disease. Boosting daily oscillations could increase clearance and prevent brain damage.
Research from Thomas Shohfi at Rensselaer Polytechnic Institute found that sell-side analyst reports contain more activist-related language and quantitative information months before hedge fund activists announce their ownership. This is associated with greater stock returns for firm shareholders, highlighting the value of traditional ...
Research at Rensselaer Polytechnic Institute finds that over 90% of people who use online delivery services would likely revert back to their original way of shopping. Delivery service users access products in four categories: groceries, food, home goods, and other items, with grocery deliveries having the highest proportion of new ado...
A new model identifies a symptom of dangerously high levels of polarization: a group's inability to unite in the face of external threats. Researchers found that extreme polarization can lead to a tipping point, where even a shock fails to reverse the self-reinforcing dynamics of division.
A team of researchers, including those from Rensselaer Polytechnic Institute and the University of Washington, have developed a neural network that can predict protein shapes with high accuracy. The network was trained on random protein sequences and generated 2,000 new proteins, many of which were successfully produced in the lab.
A study using anonymized health data found that people with poorly managed long-term glycemic control are nearly 50% more likely to require ICU treatment if they contract COVID-19. Metformin, insulin, and corticosteroids may also reduce the risk of severe COVID-19.
Researchers aim to make drug purification more efficient and scalable by understanding unwanted element interactions. They explored ligand-surface interactions using NMR spectroscopy and simulations.
Researchers developed a holographic lens that can focus light onto a single point or disperse it into its constituent colors, producing a spectrum of pure colors. The new method uses two sources of light to create a super spectral resolution optical element for detecting exoplanets with high resolution.
Researcher Jennifer Hurley is using in-vivo experimentation and big data analytics to identify environmental cues that tune the circadian clock's control over metabolism. Her study aims to find genes responsive to environmental signals, such as nutrients, to understand how environment affects sleep-wake cycle.
The Imageomics Institute, led by The Ohio State University, aims to use machine learning methodologies to extract biological traits from images of living organisms. Experts like Chuck Stewart will utilize computer vision and artificial intelligence to help infer phylogenetic traits from images.
Researchers found that taxi drivers who smoked cigarettes were more likely to cheat riders after the federal excise tax on cigarettes was raised. This spillover effect occurs when targeted individuals defraud others due to perceived unfairness and reduced buying power.
Research by Jason Huh found that Medicaid expansion can increase the number of dentists per capita in low-income counties, with a 13% increase. This growth is driven by private practice dentists responding to financial incentives offered by expanded coverage.
Researchers developed a 3D platform to study therapeutic combinations against cancer cells, allowing for rapid optimization of personalized immunotherapies. The platform demonstrated significant differences in treatment efficacy between 2D cell cultures and the 3D spheroid design.
Physicist Trevor David Rhone is using artificial intelligence to accelerate materials discovery, exploring the vast number of potential materials candidates to identify those with novel properties. His approach aims to speed up the process and enable new applications for spintronics, data storage, and quantum computing.
Scientists from Rensselaer Polytechnic Institute have successfully created a novel optoelectronic phenomenon in MoS2 by breaking its inversion symmetry using strain gradients. This breakthrough demonstrates the potential for remote thermal sensing and opens up new possibilities for designing high-efficiency optoelectronics.
Researchers from Rensselaer Polytechnic Institute demonstrate a new structure of correlated insulating state in TMDC materials, enabling greater control over excitons. This breakthrough is crucial for developing quantum emitters needed for future quantum simulation and computing.
A new model developed by Rensselaer Polytechnic Institute found that coordinated travel restrictions could have reduced the spread of COVID-19, with some restrictions reducing arrival times by up to 10 days and global infections by 6 million.
Research published in Nature found that oxygen levels in temperate freshwater lakes declined 5.5% at the surface and 18.6% in deep waters since 1980. Climate change is driving this decline, which threatens aquatic biodiversity and drinking water quality.
A recent study found that browning lakes in the northeast US are becoming increasingly light-limited, restricting algal growth and aquatic plant life. This reduction in productivity can affect fish food webs, particularly those relying on visual foraging like brook trout.
A Rensselaer-developed deep learning algorithm can identify patients at risk of cardiovascular disease using low-dose CT scans used for lung cancer screening, potentially expediting diagnoses and accelerating treatments.
George Slota, a computer scientist at Rensselaer Polytechnic Institute, has been granted a $490,000 grant to develop approaches for mapping complex petascale data to exascale hardware. His work aims to create scalable open-source software and frameworks to enable the broader scientific community to easily address these challenges.
Researchers found that combining hepatitis C drugs with remdesivir increases its effectiveness against SARS-CoV-2 in cell studies. The synergistic effect could lead to orally administered antiviral treatments, expanding COVID-19 treatment options.
Remote workers can benefit from setting clear boundaries between their personal and professional lives, according to Rensselaer Polytechnic Institute professor Timothy D. Golden. Effective communication with family members and managers is crucial for maintaining a healthy work-life balance while working from home.
A new study found that outsourcing routine tasks can be risky for vendors, particularly when it involves developing specific capabilities for the client. In contrast, well-defined tasks with trained workers and longer contracts are more beneficial for vendors.
Researchers at Rensselaer Polytechnic Institute have developed a polymerized estrogen biomaterial that shows promise as a treatment for spinal cord injuries. The study found enhanced neuroprotection in preclinical mouse models with implanted polymerized estrogen, suggesting a potential therapeutic approach.
A researcher is studying the connection between CO2 and dissolved oxygen in lakes to better understand lake carbon cycling and its impact on global carbon cycle. The study aims to develop a more accurate understanding of the relationship, which could lead to improved estimates of CO2 emissions from inland waters.
Researchers have developed a novel method for rapid and accurate glycan sequencing, reducing the time required from years to minutes. The technique utilizes a nanopore device and machine-learning software to identify sugar chains based on electrical signals generated as they pass through a tiny hole.
Researchers at Rensselaer Polytechnic Institute modified E. coli to produce chondroitin sulfate, a drug used to treat arthritis, in an animal-free fashion. The process allows for fast and efficient production of the drug, with potential applications in therapeutics and regenerative medicine.
Researchers from Rensselaer Polytechnic Institute developed a new testing strategy that effectively reduces collusion among students taking online tests. The 'distanced online testing' approach estimates each student's competence levels and assigns questions at varying times, reducing the incentive for students to receive help.
A study published in Nature Communications found that green tea compound epigallocatechin gallate (EGCG) preserves the tumor-suppressing protein p53 from degradation. This interaction increases p53 levels, which can aid in DNA repair and destroy cancerous cells.
Researchers at Rensselaer Polytechnic Institute are using a $233,776 NIH grant to study the gamma-secretase enzyme responsible for producing Amyloid-Beta 42 peptide in brain cells. The goal is to identify novel mechanisms and targets for future Alzheimer's therapeutics.
New research from Rensselaer Polytechnic Institute found that AI-driven interventions are effective in stopping the spread of misinformation when a news story first emerges. The guidance is most effective when it provides reasoning that aligns with a person's natural thought process.
A team of engineers at Rensselaer Polytechnic Institute developed an in vitro lymphatic vessel model to study tumor emboli growth. Researchers found that the model showed different growth behaviors based on cell type, linked to force generation capability, and has implications for therapeutic design.
Researchers found that mothers of children with autism spectrum disorder had significantly different metabolite levels, including lower folate and vitamin B12 levels, compared to mothers of typically developing children. These differences may be related to how carnitine is metabolized in some mothers' bodies.
Research reveals that macrophages, key immune cells, respond to pathogens and stress through circadian-controlled metabolism. The study showed an incredible amount of circadian timing in macrophage behavior, but the clock regulated immunity in unexpected ways.
A study published in Information and Organization found that employees who master technology can use everyday organizational IT to create new ideas. This increases the return on investment on existing technologies, saving organizations money by reducing the need for specialized technology.
Researchers are tracking black carbon from West Coast wildfires to study its impact on the global carbon cycle and global warming. The first flush of carbon and nutrients from burned land has been captured for the first time, revealing a previously unknown pathway in the chain that connects fire-derived black carbon to the deep ocean.
A new study from Rensselaer Polytechnic Institute found that irrelevant information and unavailable options often lead to poor choices. The researchers discovered that consumers carry cognitive costs when making decisions in environments with excess information.
A team of engineers demonstrated how a series of lunar images can provide key navigational data, allowing spacecraft to target specific locations with precision. The technique enables map-free visual odometry, gathering navigation information even when a complete map isn't available.
A new algorithm developed by Rensselaer Polytechnic Institute uses chest CT images and non-imaging data to predict COVID-19 patient outcomes. The algorithm was tested on 295 patients from three hospitals and showed promising results in determining the need for ICU intervention.
Research published in Journal of Banking and Finance found that stress tests reduce a bank's risk and increase lending capital, strengthening the entire banking industry. The study also found that investors perceive stress-tested banks as having a higher probability of earning expected gains.
Researchers at Rensselaer Polytechnic Institute developed a predictive model for an energy harvesting device that can convert mechanical vibrations into electrical energy. The model helps optimize the device to generate more power, paving the way for its potential use in wireless sensors and actuators.