A recent UA study found that Arizona EMTs have a 39% greater risk of suicide compared to the general public. The study's authors aim to address this issue by developing educational resources and resiliency training programs for EMTs. Their efforts hope to minimize the risks associated with EMS service and support community heroes in need.
Researchers found that hospitalized infants with both conditions were four times more likely to die than those with only congenital heart disease. Infants with central sleep apnea and a heart abnormality stayed twice as long and had double the hospital bills at discharge.
Researchers found that EVL protein helps contain cancer cells within the original tumor site by regulating actin cytoskeleton, which may lead to combination treatments for patients with ER-positive tumors.
Researchers at the University of Arizona College of Medicine - Tucson are studying two potential drug candidates to stop and reverse excessive scar tissue growth in the lungs. The compounds target the enzyme Nox4, which is believed to be the cause of excessive scar tissue growth.
A new four-year study aims to decrease psychological distress in cancer patients and their family caregivers during treatment using a sequential multiple assignment randomized trial. The study will employ two interventions: a printed symptom management handbook and a telephone counseling intervention.
The project aims to improve patient safety by increasing the specificity of warnings about dangerous drug combinations and identifying shared experiences to refine algorithms. It will be implemented in over 50 health-care facilities across the US.
The Southwest Environmental Health Sciences Center has been awarded a five-year grant to continue studying the effects of environmental factors on human health in arid climates. The center will expand collaboration with communities, identify potential health effects from environmental exposures, and reduce hazardous exposures.
Researchers at the University of Arizona College of Medicine - Phoenix are developing a quick and accurate diagnostic test for radiation exposure in case of a nuclear disaster. The test uses gene expression biomarkers to calculate the amount of radiation absorbed by the human body, potentially saving thousands of lives.
A study by Drs. Smithey and Nikolich-Žugich found that mice infected with cytomegalovirus had a more robust immune response to subsequent infections. This suggests that the virus may be able to harness the immune system's existing capacity, rather than weakening it as previously thought.
Researchers found that PARP inhibitors, such as rucaparib, showed promise in treating pancreatic cancer in patients with BRCA mutations. In a small study, 32% of patients experienced disease control after treatment.
A study by the University of Arizona Cancer Center found that women with cervical cancer have different communities of vaginal bacteria than those without. The 'good' bacteria, such as lactobacilli, promote a healthy environment and protect against HPV infection and cancer, while 'bad' bacteria like Sneathia increase cancer risk. Hispa...
A nationwide survey of 3,105 adults found that poor sleep quality was associated with increased likelihood of nighttime snacking and junk food cravings. Junk food cravings were linked to higher risks of obesity, diabetes, and other health problems.
Researchers have created a model to capture subtle differences in urine flow patterns using high-speed photography, which can help diagnose urethral strictures. The team plans to develop an app that allows patients to record and analyze their own urine flow images.
The University of Arizona Sleep and Health Research Program has been awarded a $3.6 million grant to study sleep health along the US-Mexico border. The Nogales Cardiometabolic Health and Sleep Study aims to investigate the relationship between sleep disturbances and cardiometabolic disease risk factors.
Researchers are studying how stress produces pain and developing a potential treatment for stress-related chronic pain conditions. The team, led by Dr. Frank Porreca, will analyze neurons in the amygdala that respond to stress through signaling at the kappa opioid receptor.
Researchers developed a computer algorithm called ALPACA to analyze gene networks in diseased cells, providing clues for cancer treatment. The approach could lead to novel strategies for preventing or curing disease, particularly for cancers that fail to respond to current treatments.
A new $1.9 million grant will help researchers discover ways to prevent Necrotizing Enterocolitis (NEC) in premature infants, a deadly disease affecting thousands annually. The study aims to create the first predictive test for NEC using fecal bile acid levels and intestinal microbiome analysis.
Theresa Currier Thomas has received a $1.65 million grant to study traumatic brain injury and develop more effective treatments. The research aims to understand how communication in the brain changes after an injury, with implications for cognition, sensory processing, and mental health.
Researchers with UAHS and ASU are studying the effect of two Medicaid enrollment freezes and subsequent expansions on healthcare utilization and expenditures among adults and children in Arizona. The study aims to inform policymakers about Medicaid funding and administration.
Researchers at the University of Arizona have discovered that brain liquefaction after a stroke can be toxic, slowly leaking into the remaining healthy portion of the brain and potentially causing harm. The study suggests that this toxic fluid may contribute to dementia after stroke.
Researchers have found that the loss of a tumor suppressor in triple-negative breast cancer provides clues for novel treatments. Drugs targeting PLK1, AURK and CHK1 may be effective for 20-30% of patients with RB-deficient tumors.
The UA-led international research consortium aims to determine the role of CC16 in persistent childhood asthma and its potential as a therapeutic intervention. The study will analyze thousands of participants followed from birth into adulthood, providing unique data on asthma persistence.
Researchers, led by Dr. Felicia Goodrum, aim to understand the virus-host interaction of human cytomegalovirus (HCMV), a member of the herpesvirus family. HCMV poses life-threatening risks in individuals with compromised immune systems and is the leading cause of infectious disease-related birth defects.
Dr. Amelia Gallitano, a UA College of Medicine - Phoenix faculty member, has received a $175,000 grant to develop the first diagnostic test for schizophrenia. The test aims to determine whether an individual has schizophrenia or a specific subtype by leveraging genes activated in response to environmental events.
A University of Arizona researcher is using a $2.3 million NIH grant to explore the role of SIRT1 in anxiety and depression. The study aims to develop novel antidepressants that target this protein, which has shown promise in reducing stress-induced anxiety.
The Navajo Nation will receive a six-year, $8.5 million grant to improve asthma care, with two proven programs being implemented in Tuba City, Chinle, and Fort Defiance. The projects aim to reduce health disparities and lower asthma exacerbations.
Researchers at the University of Arizona Cancer Center are investigating the effects of selenium supplementation on colorectal cancer risk, particularly in individuals with advanced polyps. The study aims to unravel the mystery of why some participants experienced a reduction in recurrence while others saw an increase in diabetes risk.
The University of Arizona Health Sciences has been awarded a $943,000 grant to study the effects of simulated space radiation on the human gastrointestinal tract. The Human-Microbial Cross-Talk 'gut-on-a-chip' platform will provide insights into how solar events and cosmic rays affect humans in space.
A study by UAIPW and GSA found that real-time sensors monitor federal workers' heart activity, physical movement, and sleep quality, providing data to develop best practices for optimizing workplace design for health. The research has the potential to affect millions of office workers and reduce healthcare costs.
The UA Cancer Center research team has discovered that genistein, a compound found in soy foods, can protect BRCA1, a gene crucial in thwarting tumor development in breast tissue. This finding offers new hope for treating triple-negative breast cancers, which currently have no targeted chemotherapy available.
Researchers have developed a carbon monoxide-iron-based therapy that can inhibit the effects of rattlesnake and other venomous snakebites for up to an hour in animals. The therapy blocks hemotoxic venom enzymes, preventing destruction of blood's ability to clot and reducing the risk of internal bleeding and organ damage.
The Southwest Telehealth Resource Center, funded by a $975,000 grant, assists healthcare providers in Arizona, New Mexico, Colorado, Utah, and Nevada in connecting with rural patients. The center provides training, technical assistance, and business planning support to help start-up and existing telehealth programs expand their services.
A comprehensive review by Dr. Rubin Naiman reveals that dream loss is a significant contributor to various health issues, including depression and illness. The study recommends restoring healthy dreaming through lifestyle changes and behavioral interventions.
The UA Cancer Center's research may lead to ways to target metastatic tumors by altering the depth of quiescence in cancer cells. This could make it easier for chemotherapy drugs to target and kill these cells.
The University of Arizona Health Sciences has received a $4.8 million grant from the National Institute of Allergy and Infectious Diseases to develop a live vaccine for Valley fever. Scientists aim to test the vaccine in dogs, with potential next steps including human evaluation and approval.
The University of Arizona College of Medicine - Tucson is part of a team selected for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN), a new initiative by the National Institutes of Health. The SIREN grant aims to improve emergency care and clinical outcomes through large multi-site clinical trials.
The University of Arizona researchers will investigate NHE8's role in gastrointestinal diseases, including IBD and colon cancer. They aim to understand how this protein affects goblet cell function, gut microbiome balance, and epithelial cell proliferation.
Dr. McKay's research has shown that l-dopa can delay or prevent macular degeneration in individuals with Parkinson's disease. He will now investigate the role of dopamine signaling pathways in AMD prevention.
The UA Steele Children's Research Center is studying autoimmune disease triggers with a $1.73 million NIH grant, focusing on dendritic cells and immune tolerance. The research aims to identify new targets for therapeutic approaches to restore tolerance in patients with autoimmunity.
Researchers at the University of Arizona will lead a collaborative project to develop the framework for a larger long-term study of cancer in firefighters, focusing on measuring exposures and determining mechanisms. The goal is to reduce cancer risk in firefighters through improved occupational health and safety practices.
Researchers at the University of Arizona Health Sciences aim to unlock the mystery of Alzheimer's disease in women, who are disproportionately affected by the neurodegenerative brain disease. The five-year National Institute on Aging program project grant will investigate biological transformations during perimenopause that may increas...
A UA-led study found selenium supplementation significantly increased the risk of developing type 2 diabetes, casting doubt on its effectiveness for preventing colorectal cancer. The study suggests a reevaluation of selenium supplements' use due to this potential adverse effect.
A US study found significant reductions in cocaine and methamphetamine use following government restrictions on sodium permanganate and pseudoephedrine. The disruptions, implemented in 2006 and 2007, were associated with a 32% decrease in cocaine users and a 45% decrease in methamphetamine users.
A five-year program project grant will investigate the genetic basis of acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury (VILI). The research aims to develop a more personalized medicine approach to ARDS and VILI, enabling physicians to make informed medical decisions.
A new study by the University of Arizona suggests that physicians should not predict outcomes for comatose cardiac arrest patients too soon. The study found that many patients wake up longer than expected after being rewarmed from therapeutic hypothermia treatment, with some even regaining consciousness five or seven days after admission.
A study by University of Arizona Health Sciences reveals the existence of 'T memory cells with naive phenotype' that accumulate with aging and respond to persistent viruses. These cells may hold the key to understanding and boosting immunity in older adults, who are vulnerable to infections due to weakened immune systems.
A nationwide clinical study aims to prevent and cure asthma in children at high risk, using a bacterial extract as treatment. The study enrolls over 1,000 babies from 6 to 18 months old and documents whether they develop fewer asthma symptoms than those receiving a placebo.
A University of Arizona study found that implementing a Telephone Cardiopulmonary Resuscitation (TCPR) program significantly increases survival rates and favorable outcomes for patients who experienced out-of-hospital cardiac arrests. The program, which includes guidelines-based protocols, TCPR training, and quality improvement, result...
Researchers developed a method demonstrating that independent DNA variants linked to a disease share similar biological properties. This discovery provides a more comprehensive picture of disease biology and offers the opportunity to broaden our understanding of disease and identify new therapeutic targets.
Native Americans are more likely to abstain from alcohol use than whites, with comparable rates of binge and heavy drinking. The study challenges the enduring myth that Native Americans have a higher rate of alcohol misuse.