Researchers from the University of Bath screened over 20,000 molecules to find compounds that inhibit α-methylacyl-CoA racemase (AMACR) protein, increasing its levels in prostate cancer cells. This approach identified novel small-molecule inhibitors with potential therapeutic applications.
Scientists at University of Bath have developed a new family of drugs that inhibit the AMACR protein, increasing effectiveness by 20-fold. The research provides promising avenues for treating prostate and other cancers.
Scientists developed a nanomaterial that can detect the twist direction of molecules with ultra-sensitivity, removing a major roadblock in research. The material's unique symmetry properties allow for sensitive detection of molecular chirality, which is crucial in pharmaceuticals and materials science.
A new study reveals that prioritizing a subset of the United Nations Sustainable Development Goals (SDGs) would lead to greater overall progress. Focusing efforts on Life below Water, Life on Land, and Gender Equality goals reinforces virtuous circles and achieves better outcomes.
A South African study found a strong link between low language ability and ADHD-type attention problems, as well as depressive symptoms in adolescents. The research highlights the need for better support for children with reduced language ability to prevent long-term mental health issues.
A new study shows people appreciate beauty in mathematical arguments similarly to art and music, suggesting a universal aesthetic. This finding may make abstract maths more accessible to children and has implications for maths education.
A new £11.2 million research consortium led by Professor Saiful Islam at the University of Bath aims to develop next-generation lithium batteries for electric vehicles with improved cost, performance, and range.
A new report highlights how top fashion companies' irresponsible sourcing practices are undermining efforts to end worker exploitation in South India's garment industry. Despite some improvements, social audits are often manipulated by suppliers to retain business with brands.
A study published in Nature Sustainability found that people understand sustainability in four distinct ways, but most see environmental and social outcomes as trade-offs. This suggests that effective communication is key to overcoming public scepticism about achieving a sustainable world.
Research from the University of Bath finds that negative interest rate policies are backfiring, curbing loan growth and damaging banking profits. Bank margins were being squeezed, eroding capital bases and limiting credit growth, thereby stifling domestic demand.
The University of Bath's Naturbeads technology uses cellulose to create biodegradable microbeads that can replace plastic microbeads in personal care products, reducing ocean pollution. The company will receive funding to commercialize the technology and test its use in cosmetic and personal care industries.
Researchers have achieved a major breakthrough in developing a thermally stable TB vaccine using a technique called ensilication, which protects vaccine components from heat damage. This innovation has the potential to improve the effectiveness and accessibility of vaccines globally, particularly in remote areas.
A new study suggests that digital games can be an effective way to unwind and recuperate after work. Participants who played shape-fitting games reported feeling more energized and relaxed compared to those using mindfulness apps.
Researchers found that cigarette smoke can change the DNA and characteristics of pathogenic microbes like MRSA, making them more resistant to antibiotics. This stress response sparks an emergency mutation, resulting in hardy variants that are better equipped to resist drugs.
African women often want more children than they have, challenging common misconceptions about the reasons for population change on the continent. The study highlights the importance of addressing cultural factors impacting family planning decisions.
A new study finds that patients with mental health conditions are less likely to be prescribed the most effective drug, varenicline, for quitting smoking. However, research suggests that varenicline is associated with better mental health outcomes and higher quit rates compared to nicotine replacement therapy.
Researchers have developed a satellite-based early warning system that can spot tiny movements in bridges indicating potential collapse. The technique combines data from satellites with advanced algorithms to provide near-real-time monitoring of entire structures.
A new study found that jobseekers are more likely to want to work for a company where the CEO takes a principled stance on political issues. The effect is true regardless of age, education, gender, or political orientation. Employees value humanistic values and expect goodwill from companies run by CEOs who engage in such activism.
Researchers from the University of Bath have conducted double-blind experiments showing that healthy mice pups can be born from sperm without acquired short RNA chains, challenging a proposed mechanism of epigenetic inheritance. The study undermines claims made by two 2018 papers that reported RNA addition was necessary for fertility.
Conduct Disorder is associated with an exceptionally high individual, societal, and economic burden, seven times greater than attention-deficit/hyperactivity disorder. If left untreated, CD can lead to negative consequences, including adult outcomes of antisocial or borderline personality disorder, criminal behavior, and gang involvement.
A new study has found a stark contrast between the evidence available for adult chronic pain and that conducted in children, with only six trials involving 393 participants. The lack of high-quality evidence hampers treatment options for children with chronic pain, leading to increased anxiety, depression, and isolation.
Researchers at the University of Bath have created a new way to design and manufacture personalized prosthetic liners in under a day. This innovative approach uses computer science and 3D scanning to create affordable, comfortable liners that reduce pressure on the residual limb, promoting healthy walking habits.
Scientists have detected the first polarized radio waves from a gamma ray burst jet, revealing that magnetic fields are more patchy and tangled than previously thought. The discovery was made possible by advanced radio telescopes and allows researchers to test theories about the structure of magnetic fields within jets.
A new study published in the journal Behavior Therapy found that people with hoarding problems associate objects with positive memories, making it difficult to discard them. The researchers suggest that training individuals to respond differently to these memories could enhance cognitive-behavioral therapy for hoarding.
A University of Bath researcher has created an algorithm that consistently outperforms conventional methods and other developed tools in financial trading, resulting in a 3% higher return than the benchmark U.S. Federal Reserve Funds rate. The tool's potential impact on employment at the highest banking levels is also significant.
A new study found that people with autistic traits show less empathy and reduced understanding of others' feelings. However, the researchers suggest that this lower empathy may have unforeseen benefits, such as selective empathy, which can lead to positive outcomes.
Researchers from the University of Bath have patented a technique that allows electrons to be accessed for applications including quantum computing, atom cooling, and precision measurements. The innovation uses gold nanoparticles to stabilize alkali metal vapors, enabling fast and reproducible control over the vapor density.
A study from the University of Bath aims to address human error in cyberattacks by using technology inspired from exercise and fitness apps. Researchers plan to create a prototype that gently nudges users into changing their passwords, updating privacy settings, and locking screens.
A team of scientists has created a bowl-shaped electrode that efficiently converts CO2 from gas into carbon-based fuels and chemicals. The innovative design addresses two major obstacles in the conversion process, achieving higher conversion efficiency and sensitive detection of molecules.
Researchers at the University of Bath have successfully waterproofed perovskite solar cells using a graphite coating, enabling the direct generation of clean hydrogen fuels from sunlight. This breakthrough could lead to more affordable and sustainable solar energy solutions.
The ORC Layout software uses flexible principles to suggest intuitive layouts for various screen sizes and orientations, reducing time-consuming and error-prone manual design. By combining traditional constraint-based layout and flow layout methods, the software automates UI design, making it simpler and more efficient.
Researchers at the University of Bath have discovered that targeting fungal G-protein coupled receptors could be key to controlling Fusarium head blight, a devastating disease that affects wheat crops worldwide. By studying these receptors, scientists hope to develop new approaches to control the disease and reduce crop losses.
Physicists at the University of Bath have developed a flexible way to synthesize novel nanomaterials, including Tungsten Disulphide -TMDs. The process allows for tunable materials with potential applications in optics and sensors.
A study of over 1000 frog and toad species found that those living on land invested more time and effort in parental care, leading to increased survival rates and colonization of terrestrial habitats. The research also discovered diverse parenting behaviors, including male involvement in egg protection and female nourishment.
A clinical review provides interim advice on prescribing cannabis-based products and cannabinoids for certain conditions. The guidance highlights the importance of educating patients and clinicians about different products and their effects, particularly the difference between THC and CBD.
Researchers at University of Bath created a mouse model for Joubert Syndrome by deleting portions of the Talpid3 gene, reproducing physical abnormalities and progressive ataxia in mice. The study aims to accelerate research into the disease and develop new treatments.
The University of Bath's CAMERA research centre collaborated with Aardman on a BBC virtual reality documentary about twin sisters affected by a car accident. Researchers used facial animation and motion capture tech to create realistic character movements, making the viewer feel immersed in their story.
Researchers at the University of Bath use sound waves to levitate particles, discovering multiple shapes they can assemble into when brought together. The team found that changing sound-wave frequency can manipulate clusters and influence emergent shape.
Researchers identified a novel group of stem cells controlled by mutations in the parade gene, leading to abnormally positioned pigment cells. The study showed that blood vessels play a crucial role in regulating these stem cells.
Researchers have developed a molecule that could enhance sun cream's protective effect against UVA rays, potentially benefiting patients with Friedreich's Ataxia and other mitochondrial disorders. The study found that skin cells from FA patients are up to 10 times more sensitive to UVA damage.
A recent study conducted by researchers at the University of Bath and Manchester found that broad regional accents can be a barrier to social mobility in the UK. Many teachers reported feeling pressure to modify their accents to sound more professional, leading to a mismatch between speaker and listener regarding accent in the workplace.
Researchers at the University of Bath have successfully demonstrated a new physical effect that could lead to advancements in chemical manufacturing efficiency and quality control in personalized pharmaceuticals. The technique is 100,000 times more sensitive than standard methods used today, enabling precise measurements of chirality i...
The study found that major tobacco companies are paying significantly less in Corporation Tax than they should be, with Imperial Brands and BAT making losses in the UK. The authors call for improved reporting standards and a bank-focused corporation tax surcharge to cover tobacco companies.
A new AI-powered app will monitor patients' symptoms between medical appointments and predict flare-ups using video and thermal imaging technology. The Flare Profiler aims to provide earlier detection of issues, allow earlier clinical intervention, and reduce the need for costly acute treatments.
A recent study suggests that people from diverse backgrounds share more in common than previously thought, challenging divisive narratives. The research highlights the importance of highlighting similarities over differences to promote social cohesion.
Scientists from the University of Bath and Northwestern University have developed a new ultra-sensitive sensor using a gold nanoparticle array, detecting tiny amounts of material with great potential. The sensing mechanism is affected by molecules binding to the surface of nanoparticles, providing a means for detecting small molecules ...
A joint ESA-University of Bath project aims to estimate forces experienced by lower limbs in different gravity environments, mapping variation in external loads, muscle strength, and reduced gravity effect.
The study reveals that herbal cannabis THC concentrations increased by 5% annually from 2006 to 2016, while cannabis resin THC levels rose rapidly from 10% to 17% between 2011 and 2016. This shift may offset the potential therapeutic benefits of CBD.
Food bank users face financial hardship due to benefit penalties and precarious employment. The study found that benefits like under-occupancy penalty or Jobseeker's Allowance cuts cause short-term budgetary crises, often prompting food bank use.
A new study from the University of Bath and UK universities reveals that international academics in the UK contribute significantly to public engagement, policy, industry, and non-governmental organisations. Foreign-born academics record 40% more international engagement activities than native-born colleagues.