Researchers identified genes associated with breastfeeding disorders and postpartum breast cancer in the mammary gland, revealing potential new targets for investigation. The study provides a detailed atlas of genetic expression for the adult developmental cycle of the mammary gland.
Researchers have developed an artificial cartilage material that responds to pH changes in the body, releasing anti-inflammatory drugs precisely where and when needed. This approach could improve arthritis treatment outcomes by continuously delivering pain-relieving medication.
A study found that adolescents become highly motivated to seek rewards after just a few hours of social isolation, which can be beneficial in driving them towards social interaction. However, limited opportunities for connection may lead to pursuing less healthy rewards.
Researchers discovered that a 'Goldilocks zone' of speed exists where droplets can bounce, but only if they hit surfaces between certain speeds. The study also found that smaller droplets cannot bounce regardless of their speed due to viscosity limits.
Scientists have found a way to stop brain cancer cells from spreading by 'freezing' hyaluronic acid molecules in place. This approach could lead to a new type of treatment for glioblastoma, the most aggressive form of brain cancer.
Researchers found that chronic stress triggers the release of immune cells in the brain's protective layer, contributing to depression symptoms. Blocking these cells' signaling pathway shows promise for improving behavior and alleviating depressive symptoms.
A groundbreaking biography of Æthelstan highlights his overlooked achievements and the significance of his reign in shaping modern England. Woodman argues that Æthelstan created England in 927AD, citing evidence from original diplomas, literary records, and archaeological sites.
Researchers found that differences in tectonic plate thickness explain the extensive volcanism. Thinner lithosphere funneled hot plume material, causing uplift and volcanic activity. The study sheds light on global significance of the Iceland Plume.
A new study by University of Cambridge researchers found that social media engagement flips from hostility to solidarity after a major crisis, such as the attempted assassination of Donald Trump and Joe Biden's suspension of his re-election campaign. This 'ingroup love' effect is seen in Republican and Democrat posts expressing unity a...
Researchers found that brain maps of the hand and lips remained consistent even after amputation, contradicting previous views of reorganization. This study has implications for treating phantom limb pain and controlling robotic replacement limbs via neural interfaces.
Researchers discovered a new 'In and Out' mechanism where CO₂ briefly dips into the topmost layer of water, reacts, and then reemerges. This challenges previous assumptions about where and how CO₂ can turn into carbonic acid, suggesting faster ocean acidification.
A long-standing mystery of ENOD40, a pioneering gene in legume nodulation research, has been solved. ENOD40 acts as a natural microRNA sponge to regulate the legume nodulation pathway, enabling nitrogen-fixing nodule formation. The discovery sheds light on a new layer of control in plant-microbe symbiotic relationships.
Researchers have discovered that DNA twists around itself in a structure called plectonemes, not knots, when passing through nanopores. This twisting motion generates a distinctive fingerprint in the electrical signal, offering new insights into DNA organisation and genomic integrity.
Researchers at Cavendish Laboratory create ultra-small, tuneable capacitors from graphene to achieve high modulation depths and fast speeds in terahertz modulators. The devices surpass existing modulator technologies with unprecedented intensity modulation depth and speed.
A study using stalagmite analysis found eight wet season droughts lasting over three years between 871-1021 CE, contributing to the Maya civilization's decline. This climate data aligns with historical and archaeological evidence, providing a new framework for analyzing human-climate interactions.
Researchers at the University of Cambridge have found that common blood pressure readings are inaccurate, with as many as 30% of cases of high blood pressure being missed. The team developed an experimental model to explain the physics behind these inaccuracies and identified a previously unknown factor contributing to underestimation.
Researchers have found that cicadas begin their loud choruses when the sun is precisely 3.8 degrees below the horizon, corresponding to civil twilight. The team analyzed field recordings and developed a mathematical model inspired by magnetic materials to explain this precision.
Researchers found that users who continued to use the app were more active than before, with average increases in brisk and non-brisk walking over time. After 30 months, users still used the app were doing more physical activity than beforehand.
Cambridge scientists have developed a new drug that has the potential to reduce brain damage from stroke by blocking ischaemia-reperfusion injury. The treatment, acidified disodium malonate (aDSM), was shown to decrease brain damage by as much as 60% in mice with stroke-induced brain damage.
Researchers found that INSL5 levels are high in patients with bile acid diarrhoea, leading to more watery stool. The hormone could aid development of a blood test and points towards a potential new treatment for the condition.
Scientists have developed organic molecules that can detect and manipulate electron spins using light, opening pathways for quantum sensing and molecular-based quantum information technology. The molecules' optical properties are linked to their electron's spin state, allowing for controlled interaction between the two spin radical units.
Research analysis of over 29 million people reveals a positive association between three types of air pollutant and dementia. The study found that long-term exposure to PM2.5, NO2, and soot increases the relative risk of dementia by 17%, 3% and 13%, respectively.
The discovery of exceptionally preserved early animals in the Grand Canyon sheds new light on the evolution of life during the Cambrian period. The fossils, dating back 507-502 million years, reveal complex feeding styles and unique adaptations, including hair-like extensions on crustacean bodies.
Researchers conducted the world's biggest bird survey in Colombia, recording 971 species and finding that clearing rainforest for cattle pasture causes a 60% greater biodiversity loss than previously thought. The study highlights the need for policymakers to consider the larger-scale impact of deforestation on biodiversity.
A new study reveals the personal diaries of teenage boys in Stalin's Russia, offering insights into their daily lives, family struggles, and experiences under Soviet rule. The diaries, written between 1930 and 1941, provide a unique perspective on life during this tumultuous period.
Researchers used an AI model to reassess a completed clinical trial for an Alzheimer's disease drug, finding it slowed cognitive decline by 46% in early-stage patients. The AI model predicts patient progression and allows for more precise selection of trial participants, potentially reducing the cost of developing new medicines.
Researchers decode a 800-year-old document, correcting misunderstandings of 'wolves' instead of 'elves', to reveal a medieval preacher weaving pop culture into sermons. The study sheds new light on Chaucer's references and the legend's impact on courtly romance.
A pilot clinical trial has been initiated to test the efficacy of alpelisib in treating Dent disease 2, a rare genetic disorder affecting kidney function. The trial aims to improve abnormal kidney function and potentially provide a breakthrough treatment for patients with life-threatening complications.
A team of astronomers detected a large gas giant between three and ten times the size of Jupiter hiding in the swirling disc of gas and dust surrounding a young star called MP Mus. The discovery was made using a combination of results from the Atacama Large Millimeter/submillimeter Array (ALMA) and the European Space Agency’s Gaia miss...
A new study by the University of Cambridge found that seaside and blue-colored places are more likely to evoke feelings of nostalgia in people. The research suggests that these environments have visual properties that contribute to positive emotions, including 'fractal property' and high contrast.
A new report from the University of Cambridge's Minderoo Centre for Technology and Democracy highlights the alarming trajectory of energy use by big tech companies, driven by AI growth. The report predicts that data centres could consume up to 8% of global greenhouse gas emissions by 2040, far exceeding current emissions from air travel.
Researchers at the University of Cambridge have made a groundbreaking discovery on how neural stem cell grafts can restore myelin in MS lesions in mice. The study provides critical evidence supporting the safety and efficacy of human induced neural stem cell transplantation as a potential new treatment for progressive multiple sclerosis.
Scientists have discovered that certain species of gut bacteria can absorb PFAS, potentially protecting against its harmful effects. The researchers plan to develop probiotic dietary supplements to boost the levels of these helpful microbes in our gut.
A new study has found that the capsule sponge test, a less invasive alternative to endoscopies, can accurately stratify patients with Barrett's oesophagus into high, moderate, and low risk categories. This allows for tailored monitoring, reducing unnecessary procedures and improving patient outcomes.
A new study reveals six 'closed loop' barriers that prevent doctors from using point-of-care ultrasound, leading to missed opportunities for life-saving interventions. The researchers propose practical steps to address these cultural and practical challenges, aiming to increase POCUS uptake and benefit patients.
A team of researchers has discovered that a specific radio signal can reveal the masses of the earliest stars, crucial for understanding the Cosmic Dawn. The study utilizes the 21-centimetre signal, created by hydrogen atoms filling gaps between star-forming regions, to inform predictions about future radio telescopes like REACH and SKA.
A new hypothesis suggests that prenatal sex steroid hormones and placental function played a crucial role in shaping the human brain and its cognitive traits. This may have led to increased brain size and reduced competition among males, allowing for the emergence of large social groups.
Scientists created a low-cost, durable, highly-sensitive robotic 'skin' that can detect various types of touch and pressure. The technology senses multiple physical inputs simultaneously, allowing robots to interact with their environment in a more human-like way.
A University of Cambridge report argues that menstrual tracking app data is a valuable resource for advertisers but poses significant privacy and safety risks to users. The report calls for better governance of the industry to protect user data and urges public health bodies to launch alternative apps.
A Cambridge criminologist has uncovered evidence suggesting a vengeful noblewoman, Ela Fitzpayne, had a priest, John Forde, assassinated in 1337. The records, published for the first time, reveal a complex web of relationships and motives that may have led to the murder.
A team of Cambridge chemists has developed a powerful new method for adding single carbon atoms to molecules more easily, offering a simple one-step approach. This technique targets alkenes, common in everyday products, and allows for the introduction of functional groups, enabling further versatility in molecule design.
A team of researchers used AI and human collaboration to identify six promising drug pairs against breast cancer cells. The combinations, including simvastatin and disulfiram, showed potential for further research in therapeutic repurposing.
A study by the University of Cambridge found that two-thirds of UK gig economy riders and drivers experience anxiety over ratings and pay, with over half risking health and safety while working. The study also revealed that local workers spend an average of ten hours a week waiting for jobs to come through on the app.
A team of physicists has developed a new quantum sensor that can detect vectorial magnetic fields with large dynamic range and multi-axis capabilities. The sensor is based on spin defects in hexagonal boron nitride, a two-dimensional material that offers new degrees of freedom compared to existing nanoscale sensors.
The study discovered that closely related SCAR proteins have distinct functions in plant cells, with specific regions impacting protein stability. This knowledge could improve understanding of plant-microbe interactions and develop strategies for improved plant growth.
A study by University of Cambridge scientists reveals how genetic changes in Hibiscus flowers led to the loss of visually striking bullseye patterns. The research identifies a key gene regulator and demonstrates how similar floral changes can evolve independently through changes in a single genetic element.
A new study by researchers from Cambridge Judge Business School found that CivicaScript's HCU model can reliably supply essential generic medicines at a price that saves patients over 64% and public and private insurers over 92%. The model aims to make generic drugs accessible and affordable for all.
Researchers have developed a new treatment combining venetoclax and inobrodib that shows promising results in killing B-ALL cells, potentially reducing toxic chemotherapy needs. The approach could be less toxic than current treatments and effective in all age groups.
The study highlights key findings that British poets have long explored the relationship between humans and nature through lawnmower poetry. Key examples include Andrew Marvell's 'Upon Appleton House' and Philip Larkin's 'The Mower', which reflect on cycles of violence, pastoralism, and societal problems.
A new treatment approach significantly improves survival rates for patients with aggressive, inherited breast cancers. In a trial where cancers were treated with chemotherapy followed by a targeted cancer drug before surgery, 100% of patients survived the critical three-year period post-surgery.