Articles tagged with Alcoholism
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A new study found that injury crashes were more frequent in areas with more retail alcohol outlets, including bars. The research also showed that crash risks are associated with local outlet density and alcohol availability across neighboring areas.
A new study published in Journal of the American Heart Association found that young adults who frequently binge drink are more likely to have risk factors for cardiovascular disease. The research revealed that young men who reported repeated binge drinking had higher systolic blood pressure and cholesterol levels than non-binge drinker...
A new study by Scripps Research scientists found that activating GPR139, a receptor linked to alcohol addiction, can significantly decrease drinking in alcohol-addicted rats. The researchers also discovered that the drug helps mediate physical pain associated with withdrawal in severe cases of alcohol addiction.
Researchers found that rats who chose alcohol showed similarities to human alcohol addiction diagnostic criteria, including continued use despite negative consequences. The study identified a gene expression change in the amygdala region of the brain as key to understanding this behavior.
Young adults who use alcohol and/or marijuana are more likely to engage in condomless sex, with women being at greater risk on days with substance use. The study found that women's risk of condomless sex increased by a factor of 2.12 on alcohol use days, while men's risk was only slightly higher on dual use days.
A recent rat model study found that preconception binge drinking can negatively affect future offspring's growth, social interactions, and pubertal development. The study also discovered that these effects can be passed down through generations, highlighting the importance of parental behavior in shaping offspring's traits.
A single episode of binge drinking can alter a key gene that regulates sleep, leading to increased non-rapid eye movement sleep and reduced sleep in subsequent periods. This finding may shed light on the link between sleep disturbances and alcoholism in humans.
A study published in the Journal of Studies on Alcohol and Drugs found that teenage girls who binge drink regularly have lower bone mass, even when accounting for other factors. The researchers suggest that avoiding binge drinking may help young women reach their peak bone mass and reduce their risk of osteoporosis.
Researchers found that binding to MUNC 13-1 reduces tolerance to alcohol, making it harder to become addicted. By inhibiting this protein, a pill could be developed to reduce the formation of tolerance and alleviate alcoholism.
Researchers at the University of Texas at Austin have developed a new drug, JVW-1034, that targets the sigma 2 receptor to block alcohol withdrawal symptoms and cravings. In animal models, the drug has shown no obvious side effects and has been shown to reduce alcohol consumption in rats.
A recent study found that maternal binge drinking during pregnancy and lactation can impair the mental health of their offspring, leading to mood disturbances and increased vulnerability to alcohol abuse as adolescents. The research suggests that even occasional heavy drinking can have a depressive effect on the mother and pass on chan...
Texas A&M researchers discovered that inducing persistent changes in drinking behavior by manipulating neural connections may hold the key to understanding and treating alcoholism. The study found that reversing these changes could potentially lead to a decrease in alcohol consumption.
A IU-led study found that the neurotransmitter glutamate plays a role in some alcohol cravings and relapses. Glutamate levels decreased in the brains of individuals with alcohol abuse disorder after viewing cues associated with drinking.
A recent study published in the Journal of the American Medical Association found that approximately one to five percent of first-grade children in the US have fetal alcohol spectrum disorders, rates comparable to those of autism spectrum disorders. Researchers evaluated over 6,000 children across four regions and estimated prevalence ...
A new study found that binge drinkers have higher levels of microRNA-21, which may contribute to poor vascular function and increased cardiovascular disease risk. The researchers suggest that measuring microRNA-21 could help identify patients at risk of developing cardiovascular disease.
A Baylor University study found that combining biological and non-biological beliefs about mental illness causes can lead to increased stigma. The researchers suggest that addressing these complex views in public campaigns and policy initiatives could help reduce stigma, particularly for conditions like depression and schizophrenia.
The National Institutes of Health has awarded $8 million to establish a new center for research into alcohol addiction. The Wake Forest Translational Alcohol Research Center will study behavioral and neurobiological factors associated with vulnerability and resilience to alcohol use disorder.
A simple blood test for phosphatidylethanol (PEth) can accurately identify critically ill hospital patients who misuse alcohol. The test has been found to be 88.7% accurate in identifying participants with alcohol misuse, with a level of at least 250 ng/ml being a useful cut-point.
A recent study has discovered a potential treatment for adult alcohol dependence caused by teenage binge drinking behavior. Researchers found that a specific drug can prevent the detrimental effects of adolescent binge drinking on brain development and reduce alcohol consumption in adulthood.
The study aims to determine whether evening binge drinking causes sleep apnea, neural disregulation and abnormal rhythms in blood pressure. Researchers will also examine how menstrual phases affect women's bodies and explore the impact of CPAP on negative effects.
Research suggests that binge drinking habits, rather than the amount consumed, can negatively impact a college graduate's chances of landing a job. The study found that heavy drinkers had a 10% lower probability of finding employment compared to non-binge drinkers.
Researchers found distinctive changes in brain activity of young binge-drinking college students, which may indicate early signs of brain damage. The study suggests that bingeing has tangible effects on the young brain, comparable with those seen in chronic alcoholics.
A study by Georgia State University and Purdue University found that acute alcohol intoxication amplifies the link between heavy drinking patterns and intimate partner aggression. Impulsive individuals are more likely to commit violence when intoxicated, as they focus on emotional cues in the situation.
Research found binge drinking rates decrease among college students from 42% to 37% between 1999 and 2014. However, rates increase in non-college young adults from 36% to 40% during the same period. Interventions and policy changes may contribute to the decline in college students' binge drinking rates.
A new study reveals that college students with disabilities are more likely to engage in binge drinking, with 70% reporting binge drinking at least once in the previous year. The study's findings highlight the need for targeted prevention efforts for this underserved population.
A study found that substance use, particularly binge drinking and cocaine, is associated with cognitive impairments such as attention deficits and executive functioning issues. Cognitive impairments were also linked to daily life difficulties, impeding treatment utilization, and decreased effectiveness of treatment.
A new study provides further evidence for the genetic factors underlying addictions, linking dysfunction of the CSNK1E gene to increased opioid addiction susceptibility and binge eating vulnerability. The findings suggest that shared genetic factors may underlie behavioral traits associated with addictions and eating disorders.
A new IUPUI study found that African-Americans in lower-income brackets have a lower risk of binge drinking during adolescence, but a higher risk at older ages. Higher incomes show comparable risks across racial groups.
A study published in BMC Public Health found that high alcohol consumption from age 16 to 43 is linked to higher blood glucose levels in women, while men's consumption did not show the same association. The long-term study of over 900 participants revealed an important risk factor for type 2 diabetes.
A new study published in Biological Psychiatry suggests that the MMP-9 enzyme plays a crucial role in motivation for alcohol consumption. Researchers found that mice lacking this enzyme were less motivated to drink and exhibited reduced craving during withdrawal. This discovery may lead to the development of novel treatments targeting ...
The position paper advocates for 'alternative-to-discipline' approaches, incorporating specialized treatment and return-to-practice programs. ATD strategies aim to retain, rehabilitate, and reintegrate nurses into safe professional practice.
A study published in Psychiatry Research Neuroimaging found that the reward system in women's brains is larger than in nonalcoholic women and smaller in alcoholic women than in nonalcoholic men. The study also showed a negative association between sobriety time and ventricle size, suggesting recovery from alcoholism.
A study by Laurie de Grace found that the culture of sport, particularly team sports like hockey, can increase the risk of substance addiction in elite athletes. The study revealed patterns of social acceptance, normalization of drugs and alcohol, and pressure to perform, which contribute to the development of addiction.
Researchers found that ibudilast significantly reduced craving for alcohol and improved mood in participants. The medication also showed promise in reducing the pleasurable effects of alcohol.
A new UCSF study reveals that binge drinking can cause fatty liver, inflammation and enzyme changes within seven weeks. The researchers found that even a short period of excessive drinking resulted in liver dysfunction.
A new systematic review of long-term studies found that young people exposed to more alcohol marketing are more likely to start drinking early and engage in binge drinking. The study, published in the journal Addiction, analyzed data from over 35,000 participants across seven countries.
Scientists found that Modafinil, a narcolepsy drug, reduces impulsivity in people with food addiction. The study tested 60 men and found that those who took Modafinil had significantly reduced impulsive behavior, which can lead to weight loss.
A new study suggests that male students' likelihood of becoming a perpetrator increases when they attend parties or bars more than usual. Researchers found that almost 18% admitted to sexually assaulting a woman during the study period, with frequent bar-goers being more likely to be perpetrators.
Andrew Holmes receives the ACNP Daniel H. Efron Research Award for his work on understanding the causes of alcoholism and comorbid neuropsychiatric conditions. His research has been published over 170 times, with more than 13,000 citations.
A Case Western Reserve University researcher has found that addiction treatment results improved when teens in a residential program stopped smoking. Teens who quit smoking showed lower cravings for alcohol and drugs, similar to their peers who smoked, but with better treatment duration and global functioning.
Repeated binge drinking during adolescence can alter gene expression in the brains of future generations, impacting neurological health. The study found 159 gene changes in offspring of binge-drinking mothers, 93 in offspring of binge-drinking fathers, and 244 in offspring of both parents.
Dr. Michael E. Charness has made significant contributions to understanding the effects of alcohol on the nervous system and has developed drugs that block alcohol toxicity. He is a leading expert in fetal alcohol spectrum disorders and has cared for patients with neurological disorders throughout his career.
A new study led by TSRI researchers found that a compound can specifically inactivate alcohol-linked neurons, reversing compulsive drinking behavior in rats. The findings suggest a potential new approach to treating alcohol dependence.
A study published in Molecular Psychiatry identified an enzyme whose production is turned off in nerve cells of the frontal lobe when alcohol dependence develops. This deficiency leads to continued use of alcohol despite adverse consequences. The research team hopes to develop effective medicines for treating alcoholism and contributin...
A study published in PLOS Genetics has identified hundreds of genes associated with alcohol preference in rats, suggesting a strong genetic component to alcoholism. The research found that critical regulatory pathways involving several genes were crucial in regulating the desire to drink alcohol.
Researchers identified 930 genes associated with excessive drinking behavior in genetically diverse rats, indicating a complex trait influenced by many genes and the environment. The study confirmed previously linked genes and uncovered new genetic pathways, some of which could be targets for treatment.
Scientists have pinpointed D2 neurons as key players in regulating drinking behavior, discovering they discourage action and inhibit excessive consumption. Activating these 'no-go' neurons could help prevent problem drinking behavior, paving the way for new treatments.
A new psychology study found that the ability to withhold a response to stimuli, or self-control, is a key factor in predicting binge drinking behavior. The study used regression model analysis to measure the impact of different inhibition subcomponents on binge drinking habits among young adults.
A recent study from the University of Vermont found that a simple IVR system can encourage primary care doctors to discuss patients' drinking habits. Over half of participants reported having the discussion, and those who did were more likely to receive an alcohol-related recommendation from their provider.
A recent study using PET/CT imaging found that the brains of recovering alcoholics have adapted to chemical dependency by significantly hindering metabotropic glutamate receptor subtype 5 (mGluR5) receptors, reducing cravings. This discovery could lead to new targeted drugs to limit receptor activity in patients at risk of relapse.
Long-term AA members who recited AA prayers after viewing drinking-related images reported less craving for alcohol than those who just read a newspaper. Brain activity increased in areas responsible for attention and emotion, suggesting an innate ability to minimize the effect of alcohol triggers.
Alcoholics' brains show changes in hormone and neurotransmitter levels, including increased dehydroepiandrosterone and decreased serotonin transporters. Type 1 and Type 2 alcoholics exhibit distinct differences in endocannabinoid and glutamatergic systems.
Researchers at UNC-Chapel Hill have identified a brain circuit controlling binge drinking, connecting two regions with corticotropin-releasing factor. Inhibiting this circuit in mice protects against binge alcohol drinking.
A study led by QUT researchers has shown that pindolol, a drug already approved by the FDA, can reduce ethanol consumption and is a promising treatment option for alcohol use disorders. The preclinical study suggests that pindolol could be an inexpensive and effective approach to treating alcohol dependence.
A study by Case Western Reserve University found a dose-response relationship between substance use severity and low-regard for others in adolescents. Adolescents with severe addiction were more likely to engage in riskier behaviors, such as unprotected sex and driving under the influence.
A study conducted by researchers at the University of Montreal Hospital Research Centre found that young adults who binge drink have higher blood pressure, increasing the risk of developing hypertension. The study reveals that over one in four young adults who binge drink meet the criterion for pre-hypertension.
A University of Washington study analyzed over 750 studies on marijuana and alcohol use, finding that legalization policies may lead to both substitution and complementary effects. The research highlights the difficulties in gauging the impact of a formerly illicit drug as it moves into the mainstream.
A recent study published in Biomolecules found that chronic alcohol use combined with repeated binge drinking causes significant liver damage, exceeding previous estimates. The research, conducted on mice, showed that mice exposed to both chronic and binge consumption exhibited the highest levels of liver injury.
A University of Pittsburgh-led trial found that a text message-based program successfully reduced binge drinking among 18-25 year olds. After 12 weeks, participants who received the full program reported an average of one less binge drinking day per month and a 12% reduction in binge drinking.
Researchers at the University of Missouri have found that nicotine weakens the sleep-inducing effects of alcohol by stimulating the basal forebrain. This discovery sheds light on the close link between alcohol and nicotine usage, which affects millions of people worldwide.