Research on autism and neurodevelopment. Covers screening and diagnosis gaps, rising diagnoses among girls, prenatal risks, and genomics.
A new study by MIT scholars found that voters in the US heavily rely on their pre-existing views when deciding if politicians' statements are true or not. The study used Trump's statements during the 2016 presidential primaries to examine how partisanship and prior beliefs interact with evaluations of objective fact.
Researchers found that genetic variants linked to autism spectrum disorders are also associated with enhanced cognition and intellectual achievement, suggesting positive selection during human evolution. The study analyzed over 5,000 cases of ASD and identified common variants that contribute to both conditions.
In South Carolina, a two-tiered screening process identified children with autism spectrum disorder eligible for early intensive behavioral therapy, leading to a significant increase in treatment. This policy change demonstrates the importance of early intervention in improving social interaction and communication among children with ASD.
Researchers uncovered 91 genes linked to neurodevelopmental disorders, including 38 previously unknown risk factors. The study found overlap between conditions like autism and intellectual impairments, with some genes associated with both. Additional findings suggest less severe mutations may cause autism without intellectual disability.
A study by Columbia University's Mailman School of Public Health and the Norwegian Institute of Public Health found that women infected with genital herpes during early pregnancy had twice the odds of giving birth to a child later diagnosed with autism spectrum disorder. The researchers suggested that the mother's immune response to HS...
Recent immune research advances the understanding of autism spectrum disorder (ASD), highlighting the role of immune dysregulation in its development. Therapies targeting the immune system may also have benefits beyond ASD, such as preventing attention-deficit/hyperactivity disorder.
Researchers used MRI to identify differences in brain development among high-risk infants, finding that those with autism showed faster brain growth rates between 6-12 months. These early brain changes can help predict autism diagnosis at age 2 years.
A study published in Nature used MRI scans to identify infants at high risk of developing autism as toddlers. The researchers found that brain overgrowth in the first year of life was linked to increased growth rate of overall brain volume in the second year, and this was associated with emerging autistic social deficits.
A study published in Nature found that brain imaging biomarkers at 6 and 12 months can accurately predict which infants will develop autism spectrum disorder by 24 months. The predictive power of the findings may inform the development of a diagnostic tool for ASD, potentially intervening earlier to improve outcomes.
A new study uses magnetic resonance imaging to identify infants at high risk for developing autism by age two, with over 90% accuracy. The research found that rapid growth of the brain's surface area is a key indicator of autism risk.
A new study found significant improvements in social cognition and autistic mannerisms of young subjects after outdoor adventure activities. The research suggests a promising treatment for autism spectrum disorder, with potential benefits for children's social communication skills.
A new study published in Research in Autism Spectrum Disorders found an inverse correlation between brain stem volume and aggression in children with autism. The researchers discovered that a smaller brain stem is associated with greater aggression, suggesting a potential target for treatment.
Research suggests that characteristically male brain anatomy is associated with a higher probability of autism spectrum disorder (ASD) in males. The study found that biological females with more typical male brain anatomy were about three times more likely to have ASD than those with characteristically female brain anatomy.
A study by Rosalind Franklin University of Medicine and Science identifies a specific brain circuit in the amygdala as crucial for empathy, providing hope for new treatments of social difficulties in autism. The findings suggest that targeting this region may help individuals with autism spectrum disorder develop social abilities.
A federal law aimed at ensuring equal insurance benefits for physical and mental health care has led to modest increases in healthcare utilization among children with autism spectrum disorder. Despite these gains, researchers highlight the need for stronger enforcement of the parity law to ensure adequate access to services.
Neuroscientist David Heeger proposes a new theory that explains how the brain uses prediction and inference to make decisions. The brain's neural network can process sensory input in a feedforward manner, but also runs in a feedback mode to generate predictions, and combines both modes for optimal performance.
Research from Penn State College of Medicine found that Medicaid waivers improving access to home and community-based services for children with autism also support parental employment. Waiver programs with increased cost limits and enrollment limits helped lower-income households, while those with higher limits benefited higher-income...
A study by NYU's Steinhardt School found that adults with autism view their interests positively, believing they should be encouraged. These interests also alleviate anxiety in 92% of respondents and are used as strengths in career paths and educational settings.
Researchers suggest that universal screening at 18 months and 24 months can help diagnose ASD earlier, reducing disparities among disadvantaged communities. The new policies aim to improve outcomes for relationships and careers.
A study by NYU's Steinhardt School of Culture, Education, and Human Development found that adults with autism view their interests positively and believe they should be encouraged. Many participants reported anxiety relief through engaging in their preferred interests, highlighting the potential benefits of utilizing these strengths.
A new study found that negative first impressions formed by potential social partners may reduce the quality of social experiences for people with autism. People with autism were rated similarly on trustworthiness and intelligence but less favorably on likeability and awkwardness.
Recent research from the University of Maryland found that autism-related neural defects begin early in mammalian development, when key neurons form their first circuits. This study could lead to a stronger understanding of autism and possible early intervention strategies.
Researchers created a genetically modified rat model of autism and intellectual disability to study Phelan-McDermid syndrome. The study found that oxytocin improved social memory, attention, and nerve cell activity in the rat model.
A Kaiser Permanente study found that children exposed to complications before or during birth were at a higher risk of developing autism spectrum disorder. Children with birth asphyxia and preeclampsia had a significantly increased risk, with a 10-44% greater risk compared to those without perinatal complications.
NAP, a fragment of activity-dependent neuroprotective protein, enhances Tau-microtubule interactions to block neurofibrillary tangles in Alzheimer's disease. This stabilizes microtubules and protects biological material transport in nerve cells.
A new study led by TSRI researchers discovered early brain changes in patients with Fragile X syndrome, a disorder affecting brain development. The study found that the mutation on the X chromosome triggers genome-wide DNA methylation changes, which may help explain similarities with autism spectrum disorder.
Researchers have discovered 30 genes as potential therapeutic targets for reversing Rett syndrome, a severe form of an autism spectrum disorder affecting approximately 15,000 girls and women globally. The study, led by Dr. Antonio Bedalov at Fred Hutchinson Cancer Center, aims to reactivate the silenced MeCP2 gene in affected individuals.
Reducing Pcdh10 function leads to impaired social behavior and altered amygdala circuitry, but treatment with d-cycloserine improves social interactions. The study suggests a possible target for autism treatment and parallels the male predominance of ASD in humans.
A new study by UC San Francisco researchers reveals that distinct sets of genetic defects in a single neuronal protein can cause either infantile epilepsy or autism spectrum disorders. The study identifies SCN2A as the human gene with the strongest evidence for a causal role in driving ASDs.
The 11th Annual Autism Conference will showcase notable research on sex education for teenagers with autism, promoting safety and understanding. The event will also feature studies on complex social play in children with autism and better approaches to measuring outcomes, aiming to improve the lives of individuals with autism.
A small group of children with autism and moderate to severe gastrointestinal problems showed significant improvements in behavioral and gastrointestinal symptoms after receiving a fecal transplant. Parents reported positive changes that lasted at least eight weeks after treatment, while doctor-reported symptoms decreased by 22-24%.
A study published in the journal Microbiome shows that fecal microbial transplants can improve gastrointestinal symptoms associated with autism spectrum disorders by 80%, while also improving social skills and sleep habits by 20-25%. The treatment, which involves transferring live gut bacteria from a healthy donor to a recipient, has s...
New studies by researchers at UCSF suggest that genetic variants affecting physical traits in men and women are linked to different disease risks. Autism risk is associated with genetic variants known to contribute differently to physical traits in boys and girls.
Researchers found an altered blood-brain barrier and increased intestinal permeability in individuals with autism, supporting the hypothesis that impaired barriers contribute to ASD. The study also revealed reduced expression of barrier-forming cellular components and higher expression of molecules increasing intestinal permeability in...
Researchers found a relationship between increased cortisol response to stress and gastrointestinal symptoms in children with autism. Individuals with autism who experienced frequent constipation and abdominal pain had greater cortisol levels in response to stress.
Research reveals that genes affecting social communication in children overlap with those for autism and schizophrenia, but influence risk differently at various stages of development. This study provides new insights into the genetic basis of psychiatric disorders and their relationship to social competence.
An international team of scientists has identified variants of the EBF3 gene causing a developmental disorder with features in common with autism. The discovery opens the possibility of diagnosing other patients with similar clinical disorders, providing relief to their parents and improving genetic diagnosis.
Adolescents with autism face significant stress as they transition to adulthood, with difficulties in accessing services and adapting to change being major concerns. Social workers can play a vital role in supporting families by coordinating essential services such as medical treatment and independent living.
Researchers induced autistic-like behavior in mice by lowering nSR100 protein levels, showing its causative role in autism. The study identifies nSR100 as a hub that channels molecular miscues contributing to the disorder.
A Penn Medicine study found that elevated levels of mutations in essential genes are significantly associated with an increased risk for ASD and decreased social skills. Researchers identified high-priority essential genes that could serve as targets for future studies and treatments.
Researchers found that young paternal fathers produced offspring with impaired vocal communication, while older fathers resulted in hyperlocomotion. The study provides insight into the potential mechanisms underlying the rise of these disorders.
A new method devised by Drexel University professor Connor Kerns to diagnose anxiety symptoms in children with autism has been proven effective. The Autism Spectrum Addendum (ASA) adds new questions to the Anxiety Disorders Interview Schedule - Child/Parent, helping determine behaviors related to autism versus anxiety.
Researchers challenged a popular autism hypothesis by studying brain responses to repeated visual and tactile stimuli. The findings showed that brain responses were as stable as those of healthy controls, contradicting the idea that unreliable brain activity causes autism symptoms.
A new UCLA study confirms and extends earlier findings that the brains of people with autism have a distinctive pattern of unusual gene activity. This abnormality suggests possible targets for future autism drugs, and provides insights into brain development during the first decade of life.
Researchers identified a new genetic cause of syndromic autism linked to the SLC7A5 gene, which transports amino acids into the brain. The study found that treating neurological abnormalities in mice with this gene mutation improved behavioral symptoms.
A recent study by Duke University researchers has identified a crucial link between autism and pain sensation, suggesting that the SHANK3 protein plays a key role in transmitting pain signals. The findings have significant implications for understanding autism-related sensory problems and developing effective treatments.
A national study led by Baylor College of Medicine aims to understand the link between antibiotic use and improvements in autism symptoms in some children. The research, funded by N of One: Autism Research Foundation, will examine the gut microbiome and metabolome for two years to identify potential causes and effects.
Researchers at SDSU found that brain connections in individuals with autism are more symmetrical across hemispheres, impacting cognitive development. This asymmetry may contribute to difficulties in assembling information into a cohesive narrative.
A study analyzing brain region connectivity found that people with more flexible brain states perform better on executive-function tasks. The researchers discovered five general brain patterns, with those in the most flexible states excelling in high-level cognition.
A large study of over 196,000 children found no association between a mother having an influenza infection during pregnancy and an increased risk of autism spectrum disorders. While there was a suggestion of increased risk with maternal vaccination in the first trimester, this finding was not statistically significant after adjusting f...
A study found that musical training increases brain fiber connections in children, particularly in the minor forceps area of the frontal cortex, which is linked to cognitive abilities and disorders like autism and ADHD. This new understanding may lead to targeted strategies for intervention.
A recent trial suggests vitamin D3 supplementation improves symptoms of autism spectrum disorder in children, including hyperactivity and social withdrawal. The study found significant improvements after four months of treatment, but not with a placebo.
Researchers study how young children with autism pay attention to others' eyes and find they look less at the eyes due to missing social cues. They do not actively avoid eye contact like previously thought.
Research reveals that over 68% of individuals with different types of autism share a common set of epigenetic modifications in the brain. This finding suggests that a single global epigenetic pattern could underlie diverse manifestations of the psychiatric disease. Epigenetic drugs may hold potential as novel treatments for ASD.
A new study explores the experiences of undiagnosed adults with autism spectrum disorder (ASD), revealing key themes such as managing self-doubt and finding a sense of belonging. The research aims to help healthcare professionals identify undiagnosed adults with ASD, reducing their risk of depression and anxiety.
A study by Ohio State University researchers found significant changes in the brain makeup of fetuses and newborn rats exposed to allergens during pregnancy. Animals exposed before birth showed signs of hyperactivity, antisocial behavior, and decreased anxiety, similar to ADHD. The study could help explain the links between maternal al...
Researchers found microstructural brain alternations in autism spectrum disorder using Automated Fiber Quantification technique, which provides increased sensitivity to white matter changes. The study supports the hypothesis that autism is caused by large-scale disruptions in brain connectivity.
Researchers from Scripps Florida have identified a biochemical cascade called the mTOR pathway that regulates growth in the developing brain as a key factor in autism. Mutations in PTEN affect the assembly of connections between brain areas important for social cue processing, leading to abnormal activity and deficits.
Researchers used magnetoencephalography to discover that brain activity in both the child and mother is low during gazing, but increases with parental responses. This study provides new insights into social interactions and child development for children with autism spectrum disorder.
A recent study suggests that individuals with autism may have played an important role in their social groups due to their exceptional memory skills and heightened perception. Collaborative morality, which emerged around 100,000 years ago, allowed for the acceptance and respect of people with autistic traits.