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New clues about how a high-salt diet contributes to cardiometabolic diseases found deep in the brain

A new study suggests that a high-salt diet can lead to the hyperactivity of brain cells, resulting in increased constriction of blood vessels and worsening of cardiometabolic diseases. The research also found that excessive salt consumption can trigger an unusual response in which neurons become more active despite reduced blood flow.

3D matrix ultrasound accurately identifies cardiovascular injury in healthy individuals

A new 3D matrix ultrasound method has been developed to assess cardiovascular risk in healthy individuals, offering a reliable and accurate alternative to traditional methods. The technique shows promise for personalized prevention and treatment strategies by detecting and quantifying an individual's accumulated cardiovascular damage.

SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalJACC Cardiovascular Imaging·TypeRandomized controlled/clinical trial·DateMar 16, 2022

PCORI Board of Governors approves $71.5 million to fund new research studies on topics including maternal health, autism, and urinary incontinence

The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors approved funding for 12 new comparative clinical effectiveness research studies focusing on maternal health, autism, and urinary incontinence. These studies will improve healthcare delivery and health outcomes in real-world settings.

Could a community-based approach to genetic testing help African Americans reduce risks of chronic kidney disease?

Researchers found that a community-based approach to reporting APOL1 genetic test results resulted in lower blood pressure readings among hypertensive patients. This trial suggests that involving communities in genetic testing could be beneficial for reducing the risks of chronic kidney disease.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateMar 4, 2022

Study highlights need for better education, support for patients with preeclampsia

A recent study published in BMJ Open found that many women with preeclampsia lack awareness about symptoms and long-term cardiovascular risks, underscoring the need for improved patient education and support. The research team surveyed over 800 pregnant women, revealing a significant gap in mental health support and preventive measures.

SourceBrigham and Women's Hospital·JournalBMJ Open·TypeSurvey·DateMar 3, 2022

Is blood pressure reading more accurate at home or clinic?

A new study led by Kaiser Permanente investigators found that home blood pressure monitoring is a better option for making new diagnoses of hypertension than clinic settings. This method allows for multiple readings to be collected and averaged, providing a more accurate representation of an individual's average blood pressure.

SourceKaiser Permanente·JournalJournal of General Internal Medicine·DateMar 3, 2022

A decade of women’s heart health, reexamined

A new collection of scientific articles reviews the past decade of research on women's cardiovascular health, identifying key differences between men and women. The studies highlight critical gaps in current knowledge and emphasize the need for a more tailored approach to diagnosing and treating heart disease and stroke risk in women.

SourceCedars-Sinai Medical Center·JournalCirculation Research·DateFeb 24, 2022

Salt in soluble paracetamol linked to increase risk of cardiovascular disease and death

A large study found a significant link between salt-containing paracetamol and an increased risk of heart attacks, stroke, and death. Patients with high blood pressure who took sodium-containing paracetamol had a higher risk of cardiovascular disease and death compared to those taking non-sodium-containing paracetamol.

SourceEuropean Society of Cardiology·JournalEuropean Heart Journal·TypeObservational study·DateFeb 23, 2022

Black heart disease: Two elevated biomarkers distinguish Blacks with resistant hypertension from Whites

Researchers found elevated plasma xanthine oxidase activity and more fragments of damaged mitochondrial DNA in Black adults with resistant hypertension compared to white adults. These findings suggest an important underlying cause of increased cardiovascular risk in Blacks with difficult-to-treat hypertension.

SourceUniversity of Alabama at Birmingham·JournalHypertension·TypeCase study·DateFeb 23, 2022

New health survey of indigenous Nepali people uncovers clues about the prevalence and determinants of non-communicable diseases

A recent study led by NYU Abu Dhabi researchers found that 23.8% of indigenous Nepali individuals were hypertensive, with nearly 14% having no association with identified lifestyle factors. The findings highlight the need for tailored medical research to address the unique health challenges of indigenous populations in Nepal.

SourceNew York University·JournalPLOS Global Public Health·DateFeb 18, 2022

First get your heart in shape then get pregnant

A new Northwestern Medicine study reveals that more than half of young women in the US have at least one risk factor for poor heart health before pregnancy. Optimizing heart health before and during pregnancy can prevent complications, deliver a healthy baby, and even reduce the risk of heart disease years later.

SourceNorthwestern University·JournalCirculation·DateFeb 14, 2022

Sleep apnea in pregnancy associated with increased post-delivery risk of metabolic syndrome, hypertension

Research found that pregnant women with sleep apnea are at a higher risk for developing hypertension and metabolic syndrome after delivery. A study of over 1,900 women found that those with persistent sleep apnea were three times more likely to develop hypertension and two times more likely to develop metabolic syndrome.

SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·TypeData/statistical analysis·DateFeb 11, 2022

CVIA journal publishes new issue

A new issue of the CVIA journal has been published, featuring research on the clinical significance of angiographically detectable neovascularity in patients with cardiac myxoma. Studies found that ADN was present in 42.4% of patients and was associated with higher levels of eosinophils and low-density lipoprotein cholesterol.

SourceCompuscript Ltd·JournalCardiovascular Innovations and Applications·TypeObservational study·DateJan 6, 2022

Mild autonomous cortisol secretion predominantly affects women, associated with risk for hypertension, diabetes

A cross-sectional study found that mild autonomous cortisol secretion (MACS) predominantly affects women, increasing the frequency and severity of hypertension and type 2 diabetes compared to nonfunctioning adrenal tumors. Patients with MACS carried an increased cardiometabolic burden similar to Cushing Syndrome, even without typical f...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeObservational study·DateJan 3, 2022

Disparities in blood pressure control

A study of 16,000 adults with high blood pressure found significant racial disparities in blood pressure control, linked to unequal treatment intensification and missed appointments. The research highlights the need for targeted interventions to address these inequities and improve outcomes for underserved populations.

SourceJAMA Network·JournalJAMA Cardiology·DateDec 8, 2021

Common blood pressure drug does not slow down the progression of more advanced Alzheimer’s, study finds

A phase 2 clinical trial found that losartan, commonly used to treat high blood pressure, did not significantly slow down the progression of Alzheimer's disease in people with mild-to-moderate symptoms. However, the drug may still be beneficial for those with early-stage disease if prescribed for longer periods.

SourceUniversity of Bristol·JournalThe Lancet Neurology·TypeRandomized controlled/clinical trial·DateNov 15, 2021

IU findings published in New England Journal of Medicine show effectiveness of low-cost medicine in treating high blood pressure in people with advanced kidney disease

A study published in the New England Journal of Medicine found that chlorthalidone significantly lowered blood pressure by 11mmHg in patients with stage 4 chronic kidney disease. The results also showed a 50% reduction in albuminuria, suggesting potential benefits for reducing kidney failure progression and hospitalizations.

SourceIndiana University School of Medicine·JournalNew England Journal of Medicine·DateNov 11, 2021