Articles tagged with Fungal Pathogens
A team of researchers, led by Jason Ladner, conducted a genetic study to determine the origin of snake fungal disease in the US. The study revealed that there were likely multiple introductions of the fungus from other countries, shedding light on the emergence of the disease.
Researchers found that Candida auris can reproduce through sexual activity, enabling it to generate new genetic variants. This process could lead to the creation of more drug-resistant and virulent strains.
A new biodegradable food packaging system reduces microbial contamination and extends shelf life, reducing waste and foodborne illness. The system uses pullulan-based fibers with natural antimicrobial agents, demonstrating a significant reduction in contamination and an increase in avocado shelf life.
Researchers have identified glycans in mucus that can prevent Candida albicans from causing infection. These molecules can be used to develop new antifungal medicines or make disease-causing fungus more susceptible to existing drugs.
Researchers from Arizona State University investigate autoantibodies in healthy individuals, revealing their pervasiveness and role in human health and disease. The findings aim to improve diagnostics and therapeutics for a range of illnesses.
Researchers found that salicylic acid and jasmonic acid increase in response to fungal infection, increasing plant resistance without negatively affecting growth. High levels of both hormones make trees more resistant to fungal attack.
A team of scientists has identified a protein called SsPINE1 that allows the fungus Sclerotinia sclerotiorum to overcome plant defenses. This discovery could lead to new avenues for controlling white mold stem rot pathogens and potentially even more effective, targeted breeding to make plants naturally resistant.
Scientists from around the world gather to discuss various amphibian and reptile diseases, with a focus on conservation and management strategies. The conference aims to identify solutions to mitigate the impact of these diseases on herpetofauna populations, which are currently experiencing alarming extinction rates.
A study found that apples and other fruits can host drug-resistant, pathogenic yeasts on surfaces, including Candida auris. The fungicides used to prolong shelf life may select for these resistant strains, increasing the risk of transmission.
Research reveals extracellular vesicles facilitate coordinated responses among pathogenic fungal cells, enabling them to overcome host defenses. The discovery could lead to the development of more effective therapies to combat fungal infections.
Illinois researchers identified two tropical corn germplasm lines showing promising levels of tar spot resistance, regardless of location. The study developed a new method for scoring tar spot incidence and severity, which will aid breeding programs. The findings suggest resistant hybrids are key to managing the disease long-term.
A new UMaine study shows that a specific combination of pathogens and drugs can effectively treat fungal lung infections. Researchers found that Pseudomonas aeruginosa works with fluconazole to eliminate drug tolerance and clear Candida albicans infection, suggesting that nutrient availability can impact treatment efficacy.
Researchers have sequenced the genome of Candida glabrata, a deadly yeast infection that's resistant to antifungal drugs. The study found genes associated with virulence and drug resistance, shedding light on how the pathogen spreads and evolves.
A study discovered that fungus Cyanodermella asteris synthesizes valuable compounds in plant Aster tataricus, influencing its growth. The interaction reveals a two-way dialogue between the microbe and host, with the fungus producing beneficial compounds while also being influenced by plant hormones.
Research reveals that approximately 3 out of 4 Fusarium infections of northern Vietnamese bananas are caused by F. tardichlamydosporum and F. odoratissimum, with wild bananas potentially acting as a sink for the disease. The study's findings suggest that concrete measures can be taken to control the future spreading of the disease.
Researchers have discovered a spray-induced gene silencing technique that effectively controls late blight, a devastating disease affecting potatoes and tomatoes. This environmentally friendly method has potential to reduce the usage of chemical pesticides and can be quickly adapted for new targets.
Three University of Exeter researchers Dr Jasmine Ono, Dr Luis Yanez Guerra and Dr Jane Usher have been awarded BBSRC Discovery Fellowships for innovative research in biotechnology and biological sciences. They will focus on improving scientific knowledge to develop better treatments for human fungal pathogens and understanding the ori...
A recent study by the University of Florida-led team found that common Southeastern US trees are not threatened by exotic fungi carried by wood-boring beetles. The 10-week experiment involved 55 species of Eurasian beetles and over 100 fungi samples, with none causing significant damage to saplings.
A new study reveals that the fungus Rhizopus partners with a bacteria called Ralstonia to evade immune cells and predators in soil. This partnership strategy is also used by humans' own immune cells, allowing Rhizopus to cause disease in humans.
Scientists at UC Berkeley developed a new structure prediction method that modeled 500 secreted proteins in fungal pathogen Magnaporthe oryzae. The method revealed novel sequence-unrelated effectors and common folds among plant pathogens.
A comprehensive diagnostic guide for Volutella blight has been published by the American Phytopathological Society. The guide provides a detailed review of the three fungal pathogens causing Volutella blight and compares its diagnostic traits with other boxwood fungal diseases.
Researchers at Michigan Medicine have developed a new genetic tool to study Candida auris, revealing key factors behind its shape-shifting abilities and drug resistance. The study could aid in understanding the fungus's transmission on hospital surfaces.
Research reveals a lag of 5-10 years between reduced fungicide use and decrease in fungicide-resistant pathogens. The study's findings provide insights into the impact of fungicide resistance on global distributions of pathogens.
Researchers found that many beneficial fungi in plant roots retain ancestral pathogenic capabilities, with some strains causing detrimental effects. A key gene family encoding enzymes that degrade plant cell walls was identified as a driver of these negative effects.
A team of biologists identified the fungus Verticillium dahliae's effector molecule VdAMP3, which targets beneficial organisms in the plant's microbiome to promote infection. This discovery highlights the importance of considering the entire microbiome when understanding disease.
A new study explores how plants respond differently to useful and harmful microbes, revealing that accessory chromosomes from fungal strains dictate these responses. Most plant genes are expressed similarly in response to both beneficial and pathogenic fungi, but with key differences occurring just 12 hours after interaction.
A recent study has identified 18 species of the fungus associated with olive tree anthracnose, including the most widespread in Spain, Greece, Tunisia, Portugal, and California. The research found significant differences in virulence among species and geographic regions, paving the way for more effective control methods.
Researchers from Louisiana State University discovered the molecular architecture of fungal cell walls and how they respond to stresses, paving the way for new antifungal compounds. The study's findings reveal the structural role of each major carbohydrate in the cell wall and provide a revised model of fungal cell wall organization.
Researchers have identified compounds that interfere with fungal enzymes required for fatty acid synthesis, potentially overcoming resistance to current treatments. These compounds show promise as antifungal agents, effective even against drug-resistant strains of fungi.
Research shows that infection with a fungus decreases the thermal tolerance of aphids and their beetle predator, the common ladybeetle, by more than 40 degrees Fahrenheit. Infected insects are less likely to cross into zones that are too warm or too cold, altering predator-prey interactions as the climate changes.
To combat basil downy mildew, researchers recommend using resistant basil varieties, as well as environmental modifications like keeping leaves dry and dehumidifying the air. Fungicides are also effective in controlling the disease, but their use must be alternated to prevent resistance development.
Researchers studied bicyclic monoterpene alcohols' fungicidal activity against various fungi, finding (−)-myrtenol to be most promising. The compounds also showed antioxidant and membrane-protective activities, suggesting potential practical applications.
A new vaccine has shown significant protection against Valley fever in dogs, offering hope for a potential human vaccine. The study found that two doses provided high levels of protection against the fungal disease.
A study in the Atlantic Rainforest detected high mortality rates among tiny frogs known as pumpkin toadlets infected with the chytrid fungus. The infection causes a physiological imbalance leading to death from a heart attack. Climate change and drought may exacerbate the threat to terrestrial amphibians.
Researchers at INRAE found that drought conditions do not trigger esca leaf symptoms in vines. The scientists used controlled drought conditions to monitor the physiological state of 51 Sauvignon blanc vines, half under drought, and found no correlation between drought and disease development.
A study explores how human activities on land can affect aquatic animals, specifically the fungal pathogen Cryptococcus gattii. The research found that terrestrial hotspots were likely where spores settled before infecting marine mammals in the Salish Sea.
A recent study has revealed that Fusarium wilt of cotton is more aggressive and diverse than previously understood, affecting Pima and Upland varieties. The researchers identified a population shift towards FOV4, a fourth race of the fungus, which has overcome some resistance in commercial Pima varieties.
Researchers have successfully used double-stranded RNA (dsRNA) molecules as a bio-fungicide to suppress the production of a toxin in soybean plants. The study found that dsRNAs produced in bacterial cells can effectively manage fungal diseases, reducing the need for toxic chemicals and potentially mitigating fungicide resistance.
Researchers found that complex mixtures of microbes isolated from closely related plant species increased the resistance of endangered Hawaiian plant Eugenia koolauensis to myrtle rust. This microbial treatment may be an important tool for combating disease-driven declines of endangered plants.
Researchers discovered azole-resistant Aspergillus fumigatus strains isolated from a tulip bulb have genetic recombination and resistance to multiple fungicide classes. Plant bulbs serve as an ideal niche for the pathogens to evolve their resistance, posing a global health threat.
Researchers have identified five Bacillus strains with antibiotic ability against the deadly Fusiarium wilt TR4 fungus, which is threatening global banana production. The study found that these strains can trigger direct or indirect antagonism on the fungus, providing a new biocontrol method to combat TR4.
Research from Utah State University finds that large trees in western forests benefit from mycorrhizal connections to fungi, which enhance nutrient uptake and provide defense against pathogens. Diverse forest networks offer greater protection for these giant trees.
A novel molecular assay has been developed to investigate how plant fungal pathogens circumvent the bioactivity of SDHIs. The study successfully validated known mechanisms of fungicide resistance in several agriculturally important fungal pathogens.
Plants use metabolites, chemical signals, and dual receptor recognition to distinguish beneficial microbes from pathogens. A plant cell follows a flowchart to determine the response needed based on microbe type and lifestyle.
A new disease called halo blight is threatening Michigan's hop production, causing yield losses and altering hop quality. Genetic testing revealed a novel fungal pathogen, Diaporthe sp. 1-MI, which can infect healthy hop plants and cause yellow margins on leaf lesions and browning of cones.
A new R-Gene Atlas would help identify genetic solutions to disease resistance in commercial wheat varieties, reducing global food security risks. The proposed platform would enable breeders to design gene stacks using computer modeling before starting breeding in the field, with a potential cost of £41 million.
Research finds that small chloroplasts in plant epidermal cells play a crucial role in controlling the entry of fungal pathogens. The study reveals that these chloroplasts migrate to the surface layer in response to fungal attacks, blocking their invasion into plant cells.
A complex of seven proteins is essential for Ustilago maydis to infect its host plant maize. The discovery could lead to developing new fungicides and understanding how effectors function in biotrophic fungi.
The first complete genome for the bacteria that causes bacterial spot disease in pumpkins has been assembled, providing valuable resources to understand its spread, host specificity, and potential resistance to chemical controls. The study identified key genes involved in infection and compared them with other Xanthomonas species.
Researchers have isolated multidrug-resistant Candida auris from a sandy beach and tidal swamp, revealing the fungus thrives in natural environments. Whole genome sequencing shows close relation to pathogenic strains in Southeast Asia, suggesting a possible connection between human activity and its emergence.
Researchers have identified chickpea varieties with natural resistance to Pythium ultimum, a soil-born water mold threatening the crop's production. These resistant varieties will be used to breed new kabuli chickpea varieties with improved disease resistance.
A study found that eastern newt populations in the northeastern US, Appalachian Mountains, and southeastern Canada are most vulnerable to Batrachochytrium salamandrivorans infection due to temperature fluctuations. Climate change may exacerbate this risk.
Scientists have developed a technology for obtaining magnetic nanoparticles using sweet flag extract, which exhibits antioxidant and antimicrobial properties. The new nanoparticles show antifungal activity against various species of fungi, demonstrating potential applications in agriculture and medicine.
Researchers found that common fungi in the gut teach the immune system to respond to more dangerous relatives, priming immunity against infection. The discovery offers a potential new therapy to combat deadly fungal infections.
A marine bacterium has yielded a potent new antifungal molecule, turbinmicin, effective against Candida auris and Aspergillus fumigatus resistant to major classes of drugs. Turbinmicin blocks vesicle trafficking in fungi, offering a potential solution to the growing threat of multidrug-resistant fungal infections.
Researchers have discovered that coinfection with cytomegalovirus and Aspergillus fumigatus triggers synergistic interactions between the two pathogens and human cells, leading to increased risk of complications.
Researchers at Charité and Tel Aviv University are investigating the causes of drug tolerance in invasive fungal pathogens. They aim to identify molecular pathways that explain this phenomenon and develop new treatments for life-threatening fungal infections.
A study has found fungal disease in snakes on military bases in 19 states and Puerto Rico, infecting 17% of the sampled snakes. The disease, known as ophidiomycosis, can cause a range of clinical signs, including skin lesions and death, and may threaten biodiversity across several habitats.
Researchers at University of Maryland Baltimore County identified three coordinated pathways in filamentous fungi responding to cell wall stress. By understanding how cells work and respond to stress, scientists can develop new processes for improving crop quality and creating pharmaceuticals.
Researchers discovered a fungal virus that converts a deadly fungal pathogen into a beneficial endophytic fungus in rapeseed plants. The transformed fungus boosts the plant's immune system, leading to increased weight, root growth, and resistance to diseases.