Articles tagged with Pregnancy Complications
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Elevated sFLT1 levels in mice predict preeclampsia-like symptoms, including increased angiotensin II sensitivity and decreased nitric oxide production. Treating preeclamptic mice with sildenafil reversed symptoms and improved fetal health.
The Society for Maternal-Fetal Medicine recommends the use of antenatal corticosteroids to improve outcomes for babies at risk of preterm birth in the late preterm period. The recommendations are based on a randomized trial that found significant benefits in reducing neonatal respiratory complications and other adverse outcomes.
A new study has identified pre-pregnancy heart abnormalities as a potential predictor of recurrent preeclampsia. Women who had early pregnancy-related high blood pressure were found to have abnormal changes in the size and function of their left ventricle, which pumps blood throughout the body.
Researchers found that antenatal betamethasone reduced respiratory complications, prolonged ICU stays, and bronchopulmonary dysplasia in late-preterm babies. The study enrolled 2,831 women at high risk for preterm delivery and showed a significant decrease in neonatal respiratory morbidities.
A new Tel Aviv University study found that infants born past 42 weeks have twice the risk of contracting infections, experiencing respiratory difficulties, and being admitted to NICUs compared to those born at 39-40 weeks. This is the first time the isolated effect of post-term delivery on neonatal outcomes has been determined.
Researchers have developed a blood test to predict the development of preeclampsia, enabling early diagnosis and prevention of complications. The test measures the ratio of serum sFlt-1 to PlGF proteins, allowing for reliable prediction within one week.
A recent study published in CMAJ found that planned home births among low-risk pregnant women do not increase the risk of stillbirth, neonatal death, or serious events. In fact, these women were more likely to have spontaneous vaginal births and breastfeed exclusively after delivery.
A recent study published by Hospital for Special Surgery has identified complement activation as a strong predictor of adverse pregnancy outcomes in women with lupus. Elevated levels of Bb and sC5b-9 were found to be associated with an over 50% increase in the rate of pregnancy complications.
A new treatment involving the removal of a protein called sFlt-1 from the blood has shown promise in prolonging pregnancy in women with preeclampsia. Pregnancy continued for an average of 8 days and 15 days in treated women, compared to just 3 days in untreated women.
Researchers found that women with pre-eclampsia, pre-term delivery, and small-for-gestational-age delivery are at increased risk of CVD death. High blood pressure, glycosuria, and hemoglobin decline during pregnancy also predict CVD risk. Early detection and preventive care can help prevent heart disease deaths.
A large international randomized clinical trial found that cervical pessary insertion did not reduce spontaneous preterm births or neonatal complications in women with twins. The study, published in the American Journal of Obstetrics and Gynecology, included 1,180 twin pregnancies and showed no significant differences between groups.
A new study by Montefiore and Einstein researchers recommends referring pregnant women with severe headaches and elevated blood pressure immediately for neuroimaging and monitoring. The study found that high blood pressure is a major indicator of preeclampsia, which can lead to pregnancy complications.
Researchers found that genetically distinct cells in pregnant mothers, known as microchimeric cells, promote reproductive health and prevent pregnancy complications like prematurity and stillbirth. These cells help the immune system recognize and accept non-inherited maternal antigens, suppressing an immune system attack on the fetus.
A nationwide analysis of 14,655 women found that those with endometriosis have a higher risk of early pregnancy loss and later complications. Women with a history of endometriosis are also at a higher risk of haemorrhage, preterm birth, and other issues.
A recent study published in JAMA Surgery found that pregnant women who undergo general surgical procedures do not have a higher risk of postoperative complications. The research analyzed data from over 2,700 pregnant women and 516,000 non-pregnant women, revealing no significant differences in mortality rates, overall morbidity, or pos...
Research reveals pregnant women with severe sickle cell disease are six times more likely to die during or after pregnancy. Women with the most severe form of SCD face increased risks of high blood pressure, stillbirth, preterm delivery, and smaller-than-average infants.
A cross-sectional study of 1,309 children found a significant association between low birth weight and the development of enamel defects. The study suggests that prenatal hypertension and prematurity may also contribute to the severity of these defects.
Researchers found that restricting maternal immune cells from the placenta can protect against pregnancy complications during maternal infection and complications not triggered by prenatal infection. Blocking CXCR3 effectively eliminated fetal resorption and restored healthy live offspring to Listeria infected mice.
Pregnant women after bariatric surgery are at higher risk for complications like preterm birth and small babies, but lower risk of gestational diabetes. Maternal health services should provide extra care to these women.
A recent study found that pregnant women with non-complex congenital heart disease had very low risks of arrhythmias and other heart-related complications during labor and delivery. However, these women were more likely to undergo cesarean section and remain in the hospital longer than expected.
A recent FDA and EPA guideline update suggests pregnant and breastfeeding women consume at least eight ounces to 12 ounces of fish per week. Omega-3 acids EPA and DHA found in some fish support fetal brain development and maternal health, while mercury levels in other fish pose risks.
Researchers found that DNA Methyltransferase 3b enzyme prevents Pax3 gene from turning on, leading to neural tube defects. Dr. Loeken's discovery sheds light on a biochemical pathway and may lead to better stem cell therapy.
Seroprevalence of HSV-1 remains stable, while HSV-2 decreases significantly among all races, with a greater decline for white women than black women. The study found no association between the decline in HSV-2 prevalence and a decrease in neonatal herpes cases.
A new study from China finds that obese pregnant women who adhere to an intensive nutritional and exercise program starting in the first trimester gain less weight and have fewer pregnancy complications compared to peers who receive standard prenatal care. The results show a significant reduction in gestational diabetes, pre-eclampsia,...
A study published in the FASEB Journal found that resveratrol supplements caused significant developmental abnormalities in the pancreas of offspring from pregnant monkeys, raising concerns about their safety during pregnancy. Researchers recommend that pregnant women and those planning to become pregnant avoid taking the supplement.
The US has seen a disturbing trend of increasing maternal mortality, ranking 60th globally with 796 maternal deaths in 2013. The largest increase occurred among women aged 20-24, and possible explanations include lack of prenatal care access and high caesarian section rates.
After delivering a baby, women's blood clot risk remains higher than normal for at least 12 weeks due to increased platelets and other blood-clotting factors during pregnancy. Researchers found the risk decreased over time.
Researchers at Yale University found that a combination of hydroxychloroquine may partially reverse the detrimental effects of antiphospholipid antibodies on human placental cell function, potentially benefiting pregnant women with lupus and/or antiphospholipid syndrome. This could lead to improved pregnancy outcomes for these patients.
A study at Hospital for Special Surgery identified an imbalance of angiogenic factors as a predictor of poor pregnancy outcomes in lupus patients. Elevated levels of anti-angiogenic protein sFlt1 and lower levels of placental growth factor (PIGF) were associated with increased risk of preeclampsia and other complications.
A clinical trial aims to determine the optimal timing of delivery for preterm pregnancies complicated by poor fetal growth. The study compares three groups and shows better-than-expected health outcomes for the babies, with low mortality rates and minimal severe health issues.
Research from the University of Adelaide found that pregnant women with asthma who smoke are at greater risk of complications, including preterm birth and low birth weight. The study suggests that quitting smoking during pregnancy can lead to some improvement in risks to the child.
Researchers identified two genes, HKDC1 and BACE2, associated with glucose and insulin levels in pregnant women but not in the general population. This study suggests that genetic risk profiles could one day identify individuals at elevated risk for developing gestational diabetes.
A recent study by Chinese Academy of Sciences and University of Calgary reveals a molecular feedback loop that governs the earliest steps of placenta formation, which is crucial for diagnosing and treating related pregnancy complications. The research found that this feedback loop involves Gcm1 and Fzd5 signaling cascades.
A recent study found that exercise can alleviate high blood pressure in pregnant rats by restoring balance between vascular growth factors. Exercise also improved endothelial cell function and reduced oxidative stress without compromising fetal weight.
A Loyola Medicine study reveals that breech births significantly increase the risk of complications for mothers and babies when the amniotic sac ruptures early. The study found that breech pregnancies were more likely to result in low amniotic fluid, premature birth, and serious neonatal outcomes.
Women born preterm are at higher risk of pregnancy complications, including gestational diabetes and hypertension. The risk almost doubles for mothers born before 32 weeks' gestation, according to a study published in the Canadian Medical Association Journal.
Women born preterm face a significant increase in pregnancy complications, with risks rising for more premature births. The study, led by Dr. Anne Monique Nuyt, analyzed data from 7,405 women and found that one in five pregnancies involve complications for women born before 32 weeks of gestation.
Researchers developed a method to predict if pregnant women with preterm contractions will give birth within seven days. The new blood test combines two specific proteins with an ultrasound examination of the cervix, offering possibilities to delay delivery and prepare care for premature babies.
Researchers at The Ottawa Hospital have found a protein in the blood of pregnant women that can predict if they are likely to have a fetus with growth restrictions, leading to stillbirth and long-term health complications. A widely available blood test could help develop ways to improve outcomes for women and their children.
A study of 450 pregnancies among 306 liver transplant recipients found lower miscarriage risk, higher live birth rates, and better delivery outcomes than the general population.
Researchers at Cleveland Clinic discovered that corin enzyme deficiency in the uterus may be an underlying cause of pre-eclampsia. The study found that many patients with pre-eclampsia had low levels of corin and identified corin gene mutations.
Researchers found that women with pregnancy-related hypertensive disorders or diabetes may be at increased risk of cardiovascular disease later in life. Complications such as preeclampsia and gestational diabetes were linked to higher CVD risk factors, including fasting glucose and insulin levels.
A study published in the American Journal of Perinatology found that women over 50 who undergo egg donation have similar rates of obstetrical complications as younger recipients. Despite concerns about increased risks, the research suggests thorough medical screening is essential for all pregnant women regardless of age.
Researchers at the University of Liverpool found that diabetic pregnant women experience weaker uterine contractions, increasing the risk of emergency caesarean births. Calcium levels in the uterus are also significantly reduced in these women, leading to poorly contracting muscles.
Dr. Robert Garfield, a researcher at St. Joseph's Hospital and Medical Center, has received a $100,000 phase 1 grant from the Bill and Melinda Gates Foundation to develop a device that can prevent post-partum hemorrhage, a major cause of mortality in pregnant women worldwide.
Researchers have developed a Pregnancy Viability Index (PVI) that can accurately predict the outcome of pregnancies threatening to miscarry. The PVI combines two key factors - bleeding and human chorionic gonadotrophin (hCG) levels - to provide a reliable means of predicting which pregnancies will continue and which will miscarry, ulti...
The $22.5 million study found that prenatal surgery greatly reduced the need to divert fluid away from the brain, increasing chances of children walking without crutches. Infants and mothers who underwent the procedure had better outcomes than those with post-birth surgery.
A Kaiser Permanente study found that women who developed gestational diabetes during their first and second pregnancies have a higher risk of developing it again. Hispanic and Asian Pacific Islander women are particularly at risk compared to white counterparts.
A study of 18 patients with H1N1 infection found increased risks of obstetrical complications, including fetal distress and premature delivery. The study suggests that early antiviral treatment may improve maternal outcomes and highlights the need for further research on the impact of H1N1 on pregnant women.
A global study indicates that uterine fibroid embolization has a comparable fertility rate to myomectomy, the gold standard surgical treatment, for women seeking to conceive. The procedure showed a 58.1% fertility rate, similar to myomectomy's 57% success rate.
Researchers at Yale School of Medicine have developed a simple urine test to rapidly predict and diagnose preeclampsia in pregnant women. The Congo Red Dot Test accurately predicted preeclampsia in a study of 347 pregnant women, allowing for better preventive care.
A study found that almost 1 in 5 pregnant women receive 4 or more ultrasounds, despite guidelines recommending only two. This increase is more pronounced in low-risk pregnancies, highlighting the need to review current practices.
A comprehensive review of flu seasons past reveals that pregnant women are at significant risk for serious flu-related illnesses and complications, which far surpass the risks associated with injectable vaccines. The study confirms existing CDC recommendations for prioritizing pregnant women in flu vaccination.
Research conducted by Yale University researchers found that women with preeclampsia in previous pregnancies are at higher risk of hypertension after pregnancy. Additionally, preterm delivery, preeclampsia, and low-birth weight tend to recur and increase the risk of complications in future pregnancies.
Expectant mothers who are obese are nearly 10 times more likely to suffer from chest infections and more than twice as likely to experience headaches and heartburn compared to women of a healthy weight. Obese pregnant women also face increased risks of carpal tunnel syndrome, symphysis-pubis dysfunction, and higher treatment costs.
A new study in CMAJ reports that oseltamivir and zanamivir are relatively safe for use in pregnant and breast-feeding women during the H1N1 pandemic. Pregnant women, especially those in the third trimester, are at high risk of serious complications from the flu virus.
A new study found that prenatal multivitamin supplements significantly reduce the risk of babies with a low birth weight compared to iron-folic acid supplementation. The study suggests that micronutrients supplementation could avoid approximately 1.5 million low birth weight babies globally each year.
Pregnant women undergoing thyroid and parathyroid surgery experience higher rates of complications, longer hospital stays, and increased economic costs compared to non-pregnant women. The study highlights the need for cautious approach and careful deliberation on benefits versus risks.
A study of over two million injured patients found pregnant women with seat belts had significantly fewer pregnancy-related complications than those without. Women wearing both a seat belt and air bag had the lowest rate of complications.
Women who undergo bariatric surgery experience reduced risk of medical and obstetric complications during pregnancy. The study showed a significant decrease in gestational diabetes, hypertensive disorders, and severe pre-eclampsia. However, there was a higher rate of cesarean births among women who had undergone bariatric surgery.