Articles tagged with Pregnancy Complications
A new study found significant variation in preterm birth rates among Black parents by region, country of origin, and nativity. Despite adjusting for socioeconomic, health, and behavior factors, the researchers suggest that racism and discrimination may be key drivers of these inequities.
A new Northwestern Medicine study reveals that more than half of young women in the US have at least one risk factor for poor heart health before pregnancy. Optimizing heart health before and during pregnancy can prevent complications, deliver a healthy baby, and even reduce the risk of heart disease years later.
A study found that risks of preterm birth, infant sepsis, and other adverse outcomes associated with CIN-3 treatment have decreased over time. Pregnancies after CIN-3 treatment should be managed as 'high risk' to reduce these risks.
A nationwide study led by University of Utah Health found that pregnant individuals infected with COVID-19 are about 40% more likely to develop serious complications or die during pregnancy than those who aren't infected. The severity of COVID-19 symptoms was a key indicator of heightened risk of pregnancy complications.
A recent NIH-funded study found that pregnant women with COVID-19 are at a greater risk for common pregnancy complications, including cesarean delivery and preterm birth. The study also highlighted the importance of vaccination to protect pregnant women and their babies.
Researchers at University of Illinois Chicago identified changes in the gut microbiome that can lead to gestational diabetes. They found a specific metabolite, kynurenine, that is increased during pregnancy and contributes to insulin resistance.
Researchers have detected the Delta variant of SARS-CoV-2 in the blood and placentas of women who experienced stillbirths and serious pregnancy complications. The study found that the virus was widely disseminated, causing severe inflammation of the placenta and leading to stillbirths.
A study led by the Institute for Systems Biology found that unvaccinated pregnant people with COVID-19 are more likely to have poor birth outcomes, including preterm birth and stillbirth. The risk of these outcomes is particularly high for infections during the first or second trimester.
A Rutgers study found that phthalates, commonly found in consumer products, can alter the production of essential placental hormones during pregnancy. Higher levels of phthalates have been linked to increased risk of preterm birth, gestational diabetes, and high blood pressure.
Researchers at Boston Medical Center created a new resource to manage long-term heart disease risk after specific pregnancy complications. The review synthesizes recommendations for primary care clinicians to assess and manage risk, focusing on preeclampsia, gestational diabetes, and preterm delivery.
A study published in Nature has developed a new tool to predict pre-eclampsia by analyzing genetic material in a single blood sample. The test uses machine learning and sequencing approaches to identify molecular profiles that signal fetal development and pregnancy progression, allowing for earlier detection of complications.
Researchers have developed a technique that analyzes cell-free RNA in a mother's blood to predict healthy pregnancy outcomes and detect potential complications like preeclampsia. The approach showed promise in identifying patterns of gene expression associated with a healthy pregnancy and predicting preeclampsia risk with high accuracy.
Researchers have discovered a pattern of immune activity in normal pregnancies that can detect abnormalities and predict complications. The study found elevated immune activation in the first three months, followed by a calmer phase, and higher activity in the last three months, especially when childbirth is imminent.
A recent NIH study found that pregnant women with disabilities have a significantly higher risk of severe pregnancy- and birth-related complications and death. Women with physical, sensory, or intellectual disabilities are more likely to experience preterm birth, hypertensive disorders, gestational diabetes, and cesarean delivery.
A survey of 121 fertility specialists in Australia, UK, and New Zealand found that endometrial scratching is still offered by 34% of clinics despite lack of evidence, primarily for psychological benefits. Many respondents considered the procedure's drawbacks, including pain and cost.
A study published in the British Journal of Obstetrics and Gynaecology found that women who experienced pre-eclampsia in both pregnancies were 17 times more likely to have another preterm birth. The research also showed a three-fold higher risk of subsequent pre-eclampsia after a preterm birth.
A study published in PLOS Medicine found that pregnant women with COVID-19 are more likely to experience complications during pregnancy and childbirth, including ICU admission, preeclampsia, and cesarean section. Vaccination may help protect these women, especially those at higher risk of severe COVID-19 infections.
Researchers found that COVID-19 infection in mothers leads to distinct immune changes in babies, including altered cytokine profiles and T cell responses. The study also identified potential correlations with clinical complications such as preeclampsia and fetal growth restriction.
Researchers at CNIC have identified the essential role of GPR126 in placental development, revealing its critical function in fetal growth and viability. The study also highlights a possible link between GPR126 dysfunction and pregnancy complications such as preeclampsia.
A new study estimates that banning abortion would result in a 21% increase in pregnancy-related deaths overall and a 33% increase among Black women. The study suggests that staying pregnant is more dangerous to a woman than having an abortion, with carrying a pregnancy to term being 33 times riskier than having an abortion.
A national study in Sweden suggests that the risk of adverse pregnancy outcomes from SARS-CoV-2 is likely lower than previously feared. The study found that infants born to test-positive mothers had a higher risk of neonatal care and preterm birth, but no significant difference in stillbirths or low Apgar scores.
A recent study found a significant increase in maternal deaths in the US, with drug and alcohol poisoning and homicides being major contributors. The mortality rate for all causes increased by 4.4% per year from 2015-2019.
A new study published in The New England Journal of Medicine has found no correlation between COVID-19 vaccinations and risk of first-trimester miscarriages. Vaccination during pregnancy is safe and provides protection to the newborn infant against COVID-19 infection.
The study found a significant increase in pregnancy complications during the COVID-19 pandemic, affecting approximately 1.4 million women in the US. Researchers attributed these changes to various factors, including social distancing measures, delayed prenatal care, and increased risk of maternal mortality.
A study of 7,512 pregnancies in women with congenital heart disease found no maternal deaths, but more health complications for mothers and babies compared to a control group. Babies born to CHD mothers had an increased risk of stillbirths, low birthweight, and major visible abnormalities.
A new study found a significant increase in adverse outcomes for COVID-19 positive pregnant women, including gestational diabetes, low white blood cell counts, and heavier bleeding during delivery. Respiratory complications were also witnessed in their babies, highlighting the importance of vaccinating all pregnant women against COVID-19.
A recent study published in JAMA Network investigated the potential link between epidural analgesia during labor and autism spectrum disorder in children. The research found that administration of epidural analgesia during labor was not significantly associated with autism spectrum disorder in offspring.
The USPSTF updates its recommendation to include low-dose aspirin use, which demonstrates reduced risks of perinatal death, and is consistent with its previous 2014 recommendation. Preeclampsia affects approximately 4% of pregnancies in the US and is a serious health complication.
A new study has identified unique genetic codes in the placenta that could detect pregnancy complications earlier than current tests. The researchers found specific biomarkers in maternal blood that indicate placental health and fetal well-being, allowing for real-time assessment throughout pregnancy.
A study of over 20,000 medical records found pregnant women with regurgitant or 'leaky' heart valves are up to 100 times more likely to experience cardiac complications during delivery. Women with any type of valve disease should receive increased screening and attention before and during pregnancy.
A Mount Sinai study found significant inequalities among low-risk births, with Black and Hispanic infants experiencing higher rates of unexpected complications. Hospital quality was identified as a key contributor to these disparities, with lower-quality hospitals serving more Black and Hispanic women.
This observational study found no association between prenatal antipsychotic exposure and increased risk of preterm birth, attention-deficit/hyperactivity disorder (ADHD), and autism spectrum disorder in children. The study's findings suggest that antipsychotics during pregnancy do not pose a significant risk to fetal development.
A new proposal aims to enable parents to participate in decision-making about life-saving treatment for premature infants. This balance is crucial as treatment can do great harm, while without it, the infant dies. Guidelines vary between countries, with some allowing treatment up to gestational week 23.
The US Preventive Services Task Force (USPSTF) has made a recommendation to screen for gestational diabetes in asymptomatic pregnant women at 24 weeks or later. The organization concludes that the current evidence is insufficient to make a recommendation about screening before this time frame.
Researchers from UNC School of Medicine, MAHEC, and community partners will address racial disparities in maternal care by improving data accountability and providing community-based doula support. The study aims to decrease pregnancy complications for Black women and improve outcomes in maternal care.
A study of 692 female surgeons found that nearly half experienced major pregnancy complications, including miscarriages and preterm birth. The researchers call for policy changes to support pregnant surgeons and change the culture surrounding childbearing.
Researchers from the University of Malta applied genomics to identify genetic variants causing pregnancy-induced diabetes, highlighting the disorder's genetic heterogeneity. The study provides new insights into the aetiology of complex traits and reinforces precision medicine research.
A new study from Northwestern University found that each additional pre-pregnancy cardiovascular risk factor increases the likelihood of pregnancy complications. Women with multiple risk factors are more likely to experience adverse outcomes such as maternal ICU admission, preterm birth, low birthweight, and fetal death.
A new study has found that pregnant women with migraines are at a higher risk of obstetric and postnatal complications. Migraine pregnant women had increased risks of gestational diagnosis of diabetes, hyperlipidemia, and blood clots.
Researchers developed a prototype device that measures placental oxygen levels using near-infrared light, potentially diagnosing common pregnancy complications. The study found that women with anterior placenta and complications had lower placental oxygen levels compared to healthy pregnancies.
A healthy diet before and during pregnancy may reduce risks of gestational diabetes, high blood pressure disorders, and preterm birth. Women who followed healthier eating patterns had lower risks for these pregnancy complications.
A new study published in Annals of Internal Medicine found that pregnant women hospitalized with COVID-19 and pneumonia have a lower mortality rate compared to non-pregnant women. The study analyzed medical records from over 1,100 pregnant patients and more than 9,800 non-pregnant women, revealing less than 1% of pregnant patients died...
A study found that pregnancies among women with multiple sclerosis were just as healthy as those without the disease. However, mothers with MS were more likely to have elective cesarean sections and babies born small for their gestational age due to symptoms like muscle weakness and fatigue.
A large study found that pregnant women with severe COVID-19 are more likely to experience serious complications, such as cesarean delivery, postpartum hemorrhage, and preterm birth. These outcomes can have long-term health consequences for women and their infants.
A study published in Obstetrics & Gynecology found that women with serious pregnancy complications are twice as likely to die after childbirth. The research team identified cardiac complications, acute renal failure, and strokes as the main causes of mortality after 42 days.
A meta-analysis of breast cancer survivors found they are less likely to get pregnant due to higher risks of complications. However, when they do conceive, most deliver healthy babies with no adverse effects on their long-term survival or overall health.
Researchers found genetic variation related to placental biology is partly responsible for miscarriage etiopathogenesis. Miscarriage has been linked to health outcomes such as asthma, depression, and irritable bowel syndrome.
A nationwide analysis suggests that pregnant women who undergo immediate surgery for ruptured or abscessed appendix have significantly better outcomes than those managed without an operation. Immediate surgery reduces the risk of serious complications, including loss of the fetus and mother's death.
Researchers identified three antidepressant dispensing trajectories during pregnancy: continued treatment, interrupted and resumed, and stopped. Women on continuous treatment had more frequent complications and postpartum psychiatric disorders.
A nationwide analysis of data from over 6,300 pregnant women reveals that those who underwent surgery during pregnancy had better outcomes compared to those whose surgeries were delayed. The study found a significant increase in maternal-fetal complications among women who did not have gallbladder surgery.
A new study reveals that the immune system works differently between a woman's first and second pregnancy, with potential implications for preventing miscarriages and preterm births. The research found that the immune pathways promoting a healthy first pregnancy are distinct from those in later pregnancies.
Researchers found two single-miRNA and 29 two-miRNA biomarkers in serum plasma that can predict later onset of preeclampsia in asymptomatic pregnant women. Early identification could lead to prevention and better maternal and newborn outcomes.
A Norwegian study found that women who experience complications during their first full-term pregnancy are more likely to deliver preterm in subsequent pregnancies. The researchers analyzed data from over 300,000 women and discovered a significant link between term complications and increased preterm risk.
A study of 443 women with RA found that those who followed an ideal clinical pathway had a 40% lower risk of complicated birth or miscarriage. This suggests that simple interventions can positively impact pregnancy outcomes in women with rheumatoid arthritis.
A new study found that postpartum transfusions carry a greater risk of adverse events, particularly among women with preeclampsia. The number of postpartum transfusions increased by 40% over 20 years, and the risk was twice as high for pregnant women compared to non-pregnant women.
A Mediterranean-style diet has been shown to reduce the risk of gestational diabetes (by 35%) and weight gain (average 1.25 Kg) in pregnant women, particularly those with pre-existing obesity or metabolic risks. The study suggests that this intervention could be effective for high-risk pregnant women.
A nationwide cohort study reveals that pregnant women with migraines face a higher risk of miscarriage, cesarean sections, and low birth weight babies. Migraine medication may help mitigate some complications.
A prospective study of 18,481 pregnant women found obesity in early pregnancy associated with spontaneous abortion, preterm birth, and large birth weight. Being underweight during pregnancy was linked to early neonatal deaths and low birth weight.
A study has identified early changes in RNA molecules present in the blood that can predict the likelihood of preeclampsia in lupus patients. The researchers also found that failure to modulate immune pathways during healthy pregnancy is associated with complications in pregnant lupus patients.
Researchers found that modulation of immune system during pregnancy is similar in women with and without lupus. In healthy pregnancies, key immune genes are quieted after embryo implantation, while those with preeclampsia or complications show downregulation of these genes.